Nd:YAG激光治疗白内障术后囊袋阻滞综合征的临床疗效观察

目的:探讨Nd:YAG激光治疗白内障术后囊袋阻滞综合征的临床疗效。方法:通过对9例白内障术后出现囊袋阻滞综合征的患者,进行Nd:YAG激光治疗,对其疗效进行跟踪随访,其中有3例为白内障手术后早期晶状体囊袋阻滞综合征,我们采取常规术式:Nd:YAG激光前囊膜周边造孔术,6例患者为白内障手术后晚期晶状体囊袋阻滞综合征,但是其中有4例患者为后囊膜混浊、增厚的表现,我们采取术式为Nd:YAG激光后囊膜切除术,另外2例患者伴有人工晶状体前、后表面光学部纤维增殖膜,我们采用术式为Nd:YAG激光人工晶状体前后囊膜切除术后再行晶状体后囊膜切除术。结果:9例经Nd:YAG激光治疗后患者视力均有较好的提高,没有严重的并发症发生。结论:Nd:YAG激光治疗白内障术后囊袋阻滞综合征切实有效,无并发症,是一个安全有效的方法,值得临床推广应用。     

Nd：YAG激光治疗人工晶体前纤维膜的临床分析

目的：评价Nd：YAG激光治疗白内障术后人工晶状体前纤维膜的治疗效果。方法回顾性总结Nd：YAG激光治疗白内障术后人工晶状体前纤维膜35例（35眼）。激光参数：单次脉冲能量0.8～3.3 mJ，击发次数12～116次。结果其中29例（29眼）术后视力有不同程度地提高，6眼视力无明显提高。主要并发症包括虹膜出血、人工晶状体轻微损伤、前房炎性反应及眼压升高，但对术后视力无影响。结论 Nd：YAG激光是治疗白内障术后人工晶状体前纤维膜的安全有效的治疗方法。     

青光眼白内障三联术后早期人工晶体前膜的治疗

目的探讨超声乳化白内障吸除折叠式人工晶状体植入联合复合式小梁切除术（三联手术）后早期人工晶体前膜的治疗方法,并观察疗效。方法选择72例（72眼）行超声乳化白内障吸除折叠式人工晶状体植入联合复合式小梁切除术后形成人工晶体前膜的患者,随机分为二组：观察组35例（35眼）行YAG激光人工晶体前膜切除,对照组37例（37眼）,予以地塞米松3mg,妥布霉素20mg,球结膜下注射治疗1次／d,观察1周后二组视力、人工晶体前膜清除情况,并对数据进行统计学分析。结果观察组与对照组1周后视力、人工晶体前膜清除情况分别与术前比较差异有统计学意义（P〈0．05）;二组1周后视力、人工晶体前膜清除情况比较差异有统计学意义（P〈0．05）,观察组优于对照组。结论对三联手术后人工晶状体前膜早期实行YAG激光治疗是安全有效的,值得临床推广。     

吲哚青绿前囊膜染色在过熟期白内障手术中的应用

目的：探讨过熟期白内障手术中采用吲哚青绿前囊膜染色对连续环形撕囊的作用。方法：随机选取2010年1月至12月于我院进行过熟期白内障手术患者53例（64眼）,术中黏弹剂注入前房后吲哚青绿进行前囊膜染色,撕囊镊连续环形撕囊。随机选取2009年1月至12月行过熟期白内障手术未进行前囊膜染色的患者49例（61眼）作为对照组,比较两组患者撕囊成功率及术后3个月最佳矫正视力。结果：染色组连续环形撕囊成功62眼（96.9%）,对照组成功53眼（86.9%）（χ2=4.23,P〈0.05）,术后3个月最佳矫正视力比较差异无显著性。结论：吲哚青绿前囊膜染色使前囊清晰可辨,可提高过熟期白内障患者术中撕囊成功率。     

Nd：YAG激光治疗早期人工晶状体前膜

目的总结Nd：YAG激光治疗早期人工晶状体前膜的可行性及疗效。方法对本院5年来白内障人工晶状体术后，早期晶状体前膜形成患者47例，在药物治疗欠佳时，及时进行了Nd：YAG激光晶状体前膜切除。结果病例均一次治疗成功，渗出膜吸收好，视力不同程度提高，避免了并发症。结论人工晶状体前膜影响了白内障术后视功能的恢复，早期激光治疗安全，效果可靠，缩短了病程，可以推广。     

激光在白内障术中对眼前节组织的生物学效应

本文报告了白内障囊外摘除与后房人工晶体植入术中应用钇铝石榴石(Nd:YAG)激光辅助手术30例。其中16例成熟期白内障囊外摘除术前做激光前囊膜切开术;14例未成熟期白内障在做前囊膜切开术的同时做透明皮质乳化术。结果表明,激光辅助手术在缩短手术时间、减少合并症和提高疗效方面有显著效果,并就治疗中激光对眼前节组织的生物学效应及其机理进行了讨论。     

白内障超声乳化术后后囊膜混浊的Nd∶YAG激光治疗

目的探讨Nd∶YAG激光治疗白内障超声乳化及人工晶体植入术后后囊膜混浊的疗效。　方法对 5 0例 (5 0眼 )白内障超声乳化及后房型人工晶体植入术后后囊膜混浊的患者采用Nd∶YAG激光进行治疗。　结果所有患者经一次激光治疗后视力均恢复至白内障术后的最佳视力 ,其中 1眼因术中眼球转动 ,激光误伤人工晶体后表面产生一小凹。术后 1周、1月复查 ,均未见虹膜炎、眼压升高、玻璃体前界膜破裂、黄斑囊样水肿、视网膜脱离等并发症。　结论白内障超声乳化及人工晶体植入术后的后囊膜混浊行Nd∶YAG激光治疗是安全、简便、有效的     

自体晶状体前囊膜在青光眼伴白内障联合手术中的应用

目的探讨晶状体前囊膜在青光眼与白内障联合手术中的降压效果及对功能性滤过泡维持的作用。方法采用随机对照分组的方法 ,实验组:10例青光眼伴白内障患者行小梁切除联合白内障超声乳化加人工晶体植入术,术中将自体前囊膜衬垫于巩膜瓣下;对照组:10例青光眼伴白内障患者单纯行小梁切除联合白内障超声乳化加人工晶体植入术。术后实验组眼压明显低于对照组,术后实验组功能性滤过泡存留高于对照组。结论晶状体前囊膜应用于青光眼伴白内障联合手术能有效降低眼压,长期保留功能性滤过泡,无明显并发症。     

Nd:YAG激光手术治疗白内障术后囊袋收缩综合征疗效观察

目的 研究Nd:YAG激光前囊松解术治疗白内障术后囊袋收缩综合征(CCS)患者的疗效及安全性.方法 选择2019年1月至2020年12月宝鸡市人民医院收治的100例(150眼)白内障术后CCS患者为研究对象.所有患者均行Nd:YAG激光前囊松解术治疗,治疗后,比较患者治疗前后的屈光度、视力效果及并发症发生情况.结果 治...     

白内障超声乳化术中前囊膜抛光预防患者后囊膜混浊的运用价值评估

目的 分析应用前囊膜抛光对白内障超声乳化术后后囊膜混浊进行预防的作用。方法 随机选取2021年1月—2023年8月漳州市第三医院收治的190例白内障超声乳化术患者为研究对象,按照术中有无实施前囊膜抛光治疗将患者分为两组,研究组100例患者(100眼)术中进行前囊膜抛光治疗,对照组90例患者(90眼)经过常规后囊膜抛光处理后,将人工晶状体置入,并没有进行前囊膜抛光处理。比较两组对视力分布情况、后囊膜混浊发生情况。结果 术后,研究组的视力分布情况均明显优于对照组,差异有统计学意义(P均<0.05)。术后6、12个月,研究组后囊膜混浊发生率分别为10.0%、15.0%,对照组分别为22.22%、27.78%,两组比较,差异有统计学意义(χ²=5.322、4.653,P均<0.05)。结论 白内障患者在接受白内障超声乳化术治疗时,术后开展前囊膜抛光治疗不但显著改善患者视力,而且能有效预防术后囊膜混浊。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.