共查询到6条相似文献,搜索用时 15 毫秒
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T Krings K H Chiappa H Foltys M H Reinges G R Cosgrove A Thron 《Neurosurgical review》2001,24(4):171-179
A major intrinsic limitation of transcranial magnetic stimulation (TMS) to map the human brain lies in the unclear relationship between the position of the stimulating coil on the scalp and the underlying stimulated cortex. The relationship between structure and function as the major feature constituting a brain mapping modality can therefore not be established. Recent advances in image processing allowed us to refine TMS by combining magnetic resonance imaging (MRI) modalities with TMS using a neuronavigation system to measure the position of the stimulating coil and map this position onto a MRI data set. This technique has several advantages over recent TMS mapping strategies. The position of the coil on the scalp can be held constant as verified by real time visual guidance. When evaluating higher cortical functions, the relationship between underlying cortical anatomy and the scalp stimulation site can be accurately assessed. Cortical motor output maps can be easily obtained for preoperative planning and decision making for mass lesions near rolandic cortex in patients. In conclusion, navigated TMS is a reliable alternative for localizing cortical functions and therefore may be a useful adjunct or in selected patients even a helpful alternative to other functional neuroimaging methods. 相似文献
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Naoki Kato Sarah Schilt Heike Schneider Dietmar Frey Markus Kufeld Peter Vajkoczy Thomas Picht 《Acta neurochirurgica》2014,156(5):885-895
Background
Intracranial arteriovenous malformations (AVM) are known to be potent inductors of functional plasticity, and their vasculature makes standard functional imaging difficult. Here we conducted functional mapping of both primary motor cortex and speech related areas in patients with AVM using navigated transcranial magnetic stimulation (nTMS), which has been recently proven as a reliable noninvasive modality of preoperative functional brain mapping.Method
nTMS mapping was performed in ten patients with unruptured intracranial AVMs located in or near eloquent areas. Motor mapping was conducted for six patients with AVMs near the rolandic region, and speech mapping was performed for four patients with left perisylvian AVMs. After the examination, all patients were treated with surgery, radiosurgery or observed with best medical treatment on case-by-case basis.Results
Motor mapping allowed for delineation of the primary motor cortex, even if the anatomy was severely obscured by the AVM in all cases with rolandic AVMs. No plastic relocation of the primary motor cortex was observed. Repetitive stimulation of the left ventral precentral gyrus led to speech impairments in all four cases that underwent speech mapping. Right hemispheric involvement was observed in one out of four cases and potentially indicated plastic changes. No side effects were observed.Conclusion
nTMS allowed for detailed delineation of eloquent areas even within hypervascularized cortical areas. Our observations indicate that nTMS functional mapping is feasible not only in tumorous brain lesions, but also in AVMs. 相似文献4.
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Litscher G Rachbauer D Ropele S Wang L Schikora D Fazekas F Ebner F 《Lasers in medical science》2004,19(1):6-11
Acupuncture using laser needles is a new totally painless stimulation method which has been described for the first time. This paper presents an experimental double-blind study in acupuncture research in healthy volunteers using a new optical stimulation method. We investigated 18 healthy volunteers (mean age±SD: 25.4±4.3 years; range: 21–30 years; 11 female, 7 male) in a randomized controlled cross-over trial using functional multidirectional transcranial ultrasound Doppler sonography (fTCD; n=17) and performed functional magnetic resonance imaging (fMRI) in one volunteer. Stimulation of vision-related acupoints resulted in an increase of mean blood flow velocity in the posterior cerebral artery measured by fTCD [before stimulation (mean±SE): 42.2±2.5; during stimulation: 44.2±2.6; after stimulation: 42.3±2.4 cm/s, n.s.]. Mean blood flow velocity in the middle cerebral artery decreased insignificantly. Significant changes (p<0.05) of brain activity were demonstrated in the occipital and frontal gyrus by fMRI. Optical stimulation using properly adjusted laser needles has the advantage that the stimulation cannot be felt by the patient (painless and no tactile stimulation) and the operator may also be unaware of whether the stimulation system is active. Therefore true double-blind studies in acupuncture research can be performed. 相似文献
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目的 应用功能性磁共振成像技术定位机械性伤害性刺激诱发疼痛的脑区.方法 健康男性志愿者20名,年龄20 ~ 40岁,体重指数18 ~ 25 kg/m2,采用300 g von Frey纤维丝刺激志愿者左足心.1周后行功能性磁共振成像扫描,包括10 s的初始采集信号扫描及静息态(20 s)与刺激态(20s)交替循环6次扫描.采用SPM2软件进行图像分析.结果 300 g von Frey纤维丝机械性伤害性刺激诱发疼痛的脑区包括:双侧前扣带回、右侧岛叶和双侧初级体感皮层.结论 机械性伤害性刺激诱发疼痛的脑区包括双侧前扣带回、右侧岛叶和双侧初级体感皮层. 相似文献