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Purpose Anal electric stimulation has been described as effective for fecal incontinence in several case series, but no study has
addressed possible mechanism of benefit. We wished to examine whether anal electric stimulation, using an anal probe electrode,
used on a daily basis at home for eight weeks, in the absence of any adjunctive exercises or advice, would improve symptoms
of fecal incontinence and anal sphincter pressures when compared with “sham” electric stimulation.
Methods Ninety patients (9 males, 81 females), with median age of 55 (range, 30–77) years were randomized, 47 to active anal stimulation
at 35 Hz and 43 to “sham” stimulation at 1 Hz. Outcome measures included a one-week bowel diary, symptom questionnaire, manometry,
and patients' evaluation of outcome.
Results Seventy patients completed the study. On an intention-to-treat analysis, there was no difference between the two groups on
any of the outcome measures after eight weeks. Of those who completed stimulation, 44 (63 percent) felt the stimulation had
improved their continence. Those with intact anal sphincters were not likely to rate their change more positively than those
with sphincter disruption (P = 0.71). Median patient rating of bowel control increased from 3 of 10 before stimulation to 5 of 10 after stimulation (P = 0.001).
Conclusions Eight weeks of anal electric stimulation was rated by patients as having improved their bowel control to a modest extent.
There was no statistically significant difference detected between the groups, suggesting that 1 Hz was as effective as 35 Hz.
This raises the possibility that the main effect is not sphincter contraction but sensitization of the patient to the anal
area, or simply the effect of intervening per se. Home electric stimulation is a relatively cheap and generally well-tolerated therapy in the conservative treatment of fecal
incontinence.
Supported by Action Medical Research, a medical research charity. The charity had no role in design, data collection, analysis,
or interpretation of data, nor in the decision to submit for publication.
Presented at the Royal College of Nursing Gastroenterology Forum Annual Conference, Telford, United Kingdom, November 18 to
19, 2004.
Work was conducted at St Mark's Hospital, Harrow, United Kingdom.
Reprints are not available. 相似文献
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Madhusudan Grover MD Jan Busby‐Whitehead MD Mary H. Palmer RN PhD Steve Heymen PhD Olafur S. Palsson PhD Patricia S. Goode MD Marsha Turner MS William E. Whitehead PhD 《Journal of the American Geriatrics Society》2010,58(6):1058-1062
OBJECTIVES: Determine the effect of fecal incontinence (FI) on healthcare providers' decisions to refer patients for nursing home (NH) placement. DESIGN: Survey. SETTING: Questionnaires were e‐mailed to participants' homes or offices. Participants could also volunteer at the 2008 American Geriatric Society annual meeting in Washington, DC. PARTICIPANTS: Two thousand randomly selected physician members and all 181 nurse practitioner members of the American Geriatrics Society were surveyed. MEASUREMENTS: The survey presented a clinical scenario of a 70‐year‐old woman ready for discharge from a hospital and asked about the likelihood of making a NH referral if the patient had no incontinence, urinary incontinence (UI) alone, or FI. Subsequent questions modified the clinical situation to include other conditions that might affect the decision to refer. A second survey of respondents to Survey 1 addressed possible moderators of the decision to refer (e.g., family caregiver presence, diarrhea or constipation, other physical or psychiatric limitations). Significance of differences in the relative risk (RR) for NH referral was tested using the chi‐square test. RESULTS: Seven hundred sixteen members (24.7% response rate) completed the first survey, and 686 of the 716 (96%) completed the second. FI increased the likelihood of NH referral (RR=4.71, P<.001) more than UI did (RR=1.90, P<.001). Mobility restrictions, cognitive decline, and multiple chronic illnesses increased the likelihood of NH referral more than FI alone (P<.001 for each), but in all scenarios, adding FI further increased the likelihood of referral (P<.001). Having family caregivers willing to help with toileting attenuated the likelihood of referral. CONCLUSION: FI increases the probability that geriatricians will refer to a NH. More‐aggressive outpatient treatment of FI might delay or prevent NH referral, improve quality of life, and reduce healthcare costs. 相似文献
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Alayne D. Markland DO MSc Patricia S. Goode MSN MD Kathryn L. Burgio PhD David T. Redden PhD Holly E. Richter PhD MD Patricia Sawyer PhD Richard M. Allman MD 《Journal of the American Geriatrics Society》2010,58(7):1341-1346
OBJECTIVES: To determine the incidence of fecal incontinence (FI) in community‐dwelling older adults and identify risk factors associated with incident FI. DESIGN: Planned secondary analysis of a longitudinal, population‐based cohort study. SETTING: Three rural and two urban Alabama counties (in‐home assessments 2000–2005). PARTICIPANTS: Stratified random sample of 1,000 Medicare beneficiaries: 25% African‐American men, 25% white men, 25% African‐American women, 25% white women, aged 65 and older. Eligible participants for this analysis were continent at baseline and community‐dwelling 4 years later (n=557). MEASUREMENTS: FI was defined as any loss of control of bowels occurring during the previous year. Independent variables were sociodemographics, Charlson comorbidity counts, self‐reported bowel symptoms (chronic diarrhea and constipation), depression, and body mass index (BMI). Multivariable logistic regression models were constructed using incident FI as the dependent variable. RESULTS: The incidence rate of FI at 4 years was 17% (95% confidence interval (CI)=13.7–20.1), with 6% developing FI at least monthly (95% CI=4.0–8.3). White women were more likely to have incident FI (22%) than African‐American women (13%, P=.04); no racial differences were observed in men. Controlling for age, comorbidity count, and BMI, significant independent risk factors for incident FI in women were white race, depression, chronic diarrhea, and urinary incontinence (UI). UI was the only significant risk factor for incident FI in men. CONCLUSION: The occurrence of new FI is common in men and women aged 65 and older, with a 17% incidence rate over 4 years. FI and UI may share common pathophysiologic mechanisms and need regular assessment in older adults. 相似文献
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Hee-Kyung Joh MD MPH Moo-Kyung Seong MD PhD Seung-Won Oh MD MBA 《Journal of the American Geriatrics Society》2010,58(1):116-121
OBJECTIVES: To estimate the prevalence and correlates of fecal incontinence (FI) and its effect on quality of life in ambulatory elderly people in Korea.
DESIGN: Cross-sectional, convenience sample–based survey.
SETTING: Twenty-seven senior citizen centers and two health clinics in two cities of Korea.
PARTICIPANTS: Nine hundred eighty-one relatively healthy and ambulatory community-dwelling people aged 60 and older.
MEASUREMENTS: Data were collected through in-person interviews with a structured questionnaire. Multivariate logistic regression analysis was used to determine independent risk factors for FI.
RESULTS: The prevalence of FI was 15.5%. FI was significantly associated with lower quality of life (Medical Outcomes Study 36-item Short-Form Survey) for physical and mental health. In men, FI was significantly associated with urinary incontinence (odds ratio (OR)=4.89, 95% confidence interval (CI)=2.45–9.77), hemorrhoids (OR=4.66, 95% CI=1.67–12.97), and poor self-perceived health status ( P for trend=.02). In women, FI was associated with urinary incontinence (OR=2.91, 95% CI=1.76–4.81), diabetes mellitus (OR=2.04, 95% CI=1.24–3.37), hemorrhoids (OR=2.99, 95% CI=1.31–6.83), and infrequent dietary fiber intake ( P for trend=.02).
CONCLUSION: FI is prevalent in elderly Koreans and has a profound effect on quality of life. Physicians should closely screen for FI in elderly patients with certain risk factors and evaluate to control these potentially preventable or modifiable factors. 相似文献
DESIGN: Cross-sectional, convenience sample–based survey.
SETTING: Twenty-seven senior citizen centers and two health clinics in two cities of Korea.
PARTICIPANTS: Nine hundred eighty-one relatively healthy and ambulatory community-dwelling people aged 60 and older.
MEASUREMENTS: Data were collected through in-person interviews with a structured questionnaire. Multivariate logistic regression analysis was used to determine independent risk factors for FI.
RESULTS: The prevalence of FI was 15.5%. FI was significantly associated with lower quality of life (Medical Outcomes Study 36-item Short-Form Survey) for physical and mental health. In men, FI was significantly associated with urinary incontinence (odds ratio (OR)=4.89, 95% confidence interval (CI)=2.45–9.77), hemorrhoids (OR=4.66, 95% CI=1.67–12.97), and poor self-perceived health status ( P for trend=.02). In women, FI was associated with urinary incontinence (OR=2.91, 95% CI=1.76–4.81), diabetes mellitus (OR=2.04, 95% CI=1.24–3.37), hemorrhoids (OR=2.99, 95% CI=1.31–6.83), and infrequent dietary fiber intake ( P for trend=.02).
CONCLUSION: FI is prevalent in elderly Koreans and has a profound effect on quality of life. Physicians should closely screen for FI in elderly patients with certain risk factors and evaluate to control these potentially preventable or modifiable factors. 相似文献
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Rob J. Meinds Marjolijn E. W. Timmerman Maxime M. van Meegdenburg Monika Trzpis 《Scandinavian journal of gastroenterology》2018,53(7):790-796
Objectives: Current questionnaires on defecation disorders are often brief and fail to include questions considering causative factors. Furthermore, adult and pediatric questionnaires differ, which makes it impossible to monitor defecation disorders during the transition from childhood to adulthood. With these points in mind, we developed the Groningen Defecation and Fecal Continence (DeFeC) questionnaire and its pediatric equivalent, the P-DeFeC. The aim of this paper is to introduce the questionnaires and to assess their feasibility, reproducibility and validity.Materials and methods: Various Rome IV criteria and scoring tools for constipation and fecal incontinence were incorporated, resulting in nine categories. Feasibility and reproducibility were assessed by performing a test–retest survey in 100 adult participants. Concurrent validity was assessed in 27 patients and 18 healthy volunteers by comparing questionnaire-based diagnoses of constipation and fecal incontinence to final diagnoses based on anorectal function tests.Results: There were no remarks on the understandability of any questions. The Cohen’s kappa coefficient of all main questions ranged from 0.26 to 1.00, with an average of 0.57. All but one category showed moderate agreement or higher. The sensitivity of the questionnaire-based diagnosis of constipation was 75%; specificity was 100%. The sensitivity of the questionnaire-based diagnosis of fecal incontinence was 77%; specificity was 94%.Conclusions: Overall reproducibility of the Groningen DeFeC questionnaire is acceptable and its validity is good. This makes it a feasible screening tool for defecation disorders and, equally important, with these questionnaires defecation disorders can now be monitored during the transition from childhood to adulthood. 相似文献
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Scintigraphic Assessment of Retrograde Colonic Washout in Fecal Incontinence and Constipation 总被引:3,自引:0,他引:3
Christensen P Olsen N Krogh K Bacher T Laurberg S 《Diseases of the colon and rectum》2003,46(1):68-76
PURPOSE: This study aimed to evaluate the colorectal luminal transport obtained by retrograde colonic washout with a new scintigraphic technique.
METHODS: Nineteen patients (5 with spinal cord lesion, 6 with idiopathic fecal incontinence, and 8 with idiopathic constipation) treated with retrograde colonic washout took indium-111–labeled polystyrene pellets to label the bowel contents. Technetium-99m-diethylene-triamine-pentaacetic acid was mixed with the irrigation fluid to assess its extent within the colorectum. Scintigraphy was performed before and after a standardized washout procedure. The colorectum was divided into four segments: the cecum and ascending colon, the transverse colon, the descending colon, and the rectosigmoid. Assuming ordered evacuation of the colorectum, the contribution of each colonic segment to the total evacuation was expressed in percent of the original segmental counts. The contributions of each segment were summed to reach a total defecation score (range, 0–400), and directional segmental transports were estimated.
RESULTS: The defecation score in patients with idiopathic constipation (median, 59; range, 21–130) differed significantly (P < 0.05) from the scores in those with spinal cord lesions (median, 204; range, 108–323) and idiopathic fecal incontinence (median, 188; range, 155–234). Thus, patients with spinal cord lesion or idiopathic fecal incontinence were able to empty most of the rectosigmoid and most of the descending colon, but those with idiopathic constipation could only empty 59 percent of the rectosigmoid. The irrigation fluid on average reached a point just beyond the right colic flexure that correlated with the defecation score (r2 = 0.58, P < 0.001).
CONCLUSION: The effect of retrograde colonic washout was significantly better in spinal cord lesion and idiopathic fecal incontinence than in idiopathic constipation, and its effect correlated with the extent to which the irrigation fluid had entered the colorectum. 相似文献
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Jae Heon KIM Kwang Woo LEE Jun Mo KIM Min Eui KIM Young Ho KIM 《Lower urinary tract symptoms.》2013,5(3):154-158
Objectives: The aim of the present study was to investigate the risk factors for the development of de novo stress urinary incontinence (SUI) and mixed urinary incontinence (MUI) after surgical removal of a urethral diverticulum (UD). Methods: We identified 35 consecutive women that underwent surgical removal of a UD between November 2002 and December 2009, and we retrospectively reviewed their medical records, including patient demographics, pelvic magnetic resonance imaging (MRI), presenting symptoms related to voiding, and outcomes. Results: Among the 35 patients we identified, 28 were included in the study. After UD removal, five of the 28 patients (17.8%) developed de novo MUI, and four of the 28 patients (14.2%) developed de novo SUI. The incidences of SUI and MUI were significantly higher in patients who had a UD that measured over 3 cm in diameter and in patients in whom the UD was located in the proximal urethra. Of the seven patients with a diverticulum over 3 cm, SUI occurred in three (42.8%) (P = 0.038) and MUI occurred in five (45.4%) (P < 0.001). Of the 11 patients with a diverticulum located in the proximal urethra, SUI occurred in five (45.4%) (P = 0.011) and MUI occurred in four (36.4%) (P = 0.011). Conclusion: Significant risk factors for the development of SUI and MUI after transvaginal simple diverticulectomy include a UD measuring over 3 cm and a UD located in the proximal urethra. 相似文献
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Electrophysiologic Studies and Clinical Findings in Females With Combined Fecal and Urinary Incontinence: A Prospective Study 总被引:2,自引:0,他引:2
Lacima G Pera M Valls-Solé J González-Argenté X Puig-Clota M Espuña M 《Diseases of the colon and rectum》2006,49(3):353-359
Purpose Several clinical, urodynamic, and manometric findings suggest neurologic damage as a contributing factor in the development
of combined fecal and urinary incontinence. In this study, we wanted to test the hypothesis of pudendal nerve neuropathy being
a more frequent lesion in patients with double incontinence compared with patients with isolated fecal incontinence.
Patients Ninety-three females with combined fecal and urinary incontinence and 36 females with isolated fecal incontinence were investigated.
All patients underwent anal manometry, endoanal ultrasound, electromyography, and pudendal nerve terminal motor latency.
Results No statistically significant differences were found in the age, history of vaginal delivery, and chronic straining between
both groups. However, the rate of postmenopausal females was higher in the combined fecal and urinary incontinence group (85
vs. 67 percent; P = 0.02). Menopause was an independent risk factor of having double incontinence (odds ratio, 1.4; P = 0.02). Concentric needle electromyography of the external anal sphincter revealed increased duration of the motor unit
potentials in 43 and 53 percent of patients with combined fecal and urinary incontinence and isolated fecal incontinence,
respectively (P = 0.28). An increased number of polyphasic motor unit potentials was detected in 52 and 58 percent (P = 0.6). There was no statistically significant difference in the prevalence of bilateral (20 vs. 27 percent) or unilateral (23 vs. 14 percent) prolonged mean pudendal nerve terminal motor latency between both groups (P = 0.3).
Conclusions Pudendal neuropathy is not a distinct characteristic of patients with double incontinence. The prevalence of pudendal neuropathy
in these patients is similar to that observed in patients with isolated fecal incontinence. Others factors should be investigated
to explain the common association of both types of incontinence.
Presented at the meeting of The American Society of Colon and Rectal Surgeons, Philadelphia, Pennsylvania, April 30 to May
5, 2005, and the International Symposium Neurogastroenterology and Motility, Toulouse, France, July 3 to 6, 2005.
Reprints are not available. 相似文献
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Objectives: To investigate the association between dietary nutrients and urinary incontinence (UI) among Japanese adults. Methods: A total of 1017 adults (710 men and 307 women) were recruited from the community in central and southern Japan. A structured questionnaire, incorporating the International Consultation on Incontinence Questionnaire‐Short Form (ICIQ‐SF) and a validated food frequency questionnaire, was administered to participants by face‐to‐face interview. Information on dietary nutrients intake from each food item was obtained using the Japanese food composition tables. Logistic regression analyses were performed to determine the association between nutrients intake and the prevalence of UI. Results: The observed prevalence of UI was 8.7% (n = 62) for men (mean age 62.5 years) and 29% (n = 89) for women (mean age 62.0 years) based on the ICIQ‐SF criterion. Of the 50 dietary nutrients and micronutrients considered, soluble fiber (P = 0.03) and omega‐6 polyunsaturated fatty acids (P = 0.01) were found to be inversely associated with the UI prevalence for men, whereas increasing the intake of lutein/zeaxanthin appeared to be marginally associated (P = 0.04) with a reduced risk of UI for women. Conclusion: Three dietary nutrients have been identified to be associated with UI in middle‐aged and older Japanese adults. Further research and clinical trials are needed to ascertain the effects of dietary nutrients on UI. 相似文献
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Tannenbaum C Brouillette J Korner-Bitensky N Dumoulin C Corcos J Tu le M Lemieux MC Ouellet S Valiquette L 《Journal of the American Geriatrics Society》2008,56(3):542-547
OBJECTIVES: To report on the content development, construct validity, and reliability testing of the Geriatric Self-Efficacy Index for Urinary Incontinence (GSE-UI).
DESIGN: Prospective cohort study.
SETTING: Six UI outpatient clinics in Quebec, Canada.
PARTICIPANTS: Community-dwelling incontinent men and women aged 65 and older.
MEASUREMENTS: Thirty-eight items were generated using a literature search and interdisciplinary panel of experts. Item reduction was achieved through field-testing with 75 older men and women with UI attending an information session. The final 20-item draft, measuring older adults' level of confidence in preventing urine loss, was administered to a new group of consecutive patients 1 week before and at the time of their first visit to the UI clinic to enable evaluation of test–retest reliability. A 3-day voiding diary, quantifying the frequency of UI, and the Incontinence Quality of Life questionnaire were used to test construct validity.
RESULTS: One hundred sixteen of 300 eligible patients (39%) participated (mean age±standard deviation 74±6, range 65–87). The GSE-UI items showed normal distributions and no ceiling effects. Self-efficacy scores ranged from 16 to 193 (mean 104±41, possible range 0–200) and correlated positively with quality of life scores ( r =0.7, P <.001) and negatively with UI severity ( r =−0.4, P <.001). Internal consistency for the GSE-UI was 0.94 (Cronbach alpha). Initial test–retest reliability of the 20 items using intraclass correlations ranged from 0.50 to 0.86.
CONCLUSION: The GSE-UI will enable measurement of whether a person's confidence in their ability to prevent urine loss is an important mechanism contributing to improvements in UI. 相似文献
DESIGN: Prospective cohort study.
SETTING: Six UI outpatient clinics in Quebec, Canada.
PARTICIPANTS: Community-dwelling incontinent men and women aged 65 and older.
MEASUREMENTS: Thirty-eight items were generated using a literature search and interdisciplinary panel of experts. Item reduction was achieved through field-testing with 75 older men and women with UI attending an information session. The final 20-item draft, measuring older adults' level of confidence in preventing urine loss, was administered to a new group of consecutive patients 1 week before and at the time of their first visit to the UI clinic to enable evaluation of test–retest reliability. A 3-day voiding diary, quantifying the frequency of UI, and the Incontinence Quality of Life questionnaire were used to test construct validity.
RESULTS: One hundred sixteen of 300 eligible patients (39%) participated (mean age±standard deviation 74±6, range 65–87). The GSE-UI items showed normal distributions and no ceiling effects. Self-efficacy scores ranged from 16 to 193 (mean 104±41, possible range 0–200) and correlated positively with quality of life scores ( r =0.7, P <.001) and negatively with UI severity ( r =−0.4, P <.001). Internal consistency for the GSE-UI was 0.94 (Cronbach alpha). Initial test–retest reliability of the 20 items using intraclass correlations ranged from 0.50 to 0.86.
CONCLUSION: The GSE-UI will enable measurement of whether a person's confidence in their ability to prevent urine loss is an important mechanism contributing to improvements in UI. 相似文献
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Urinary Incontinence in Older Women: The Role of Body Composition and Muscle Strength: From the Health,Aging, and Body Composition Study
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Anne M. Suskind MD MS Peggy M. Cawthon PhD MPH Sanae Nakagawa MA Leslee L. Subak MD Ilse Reinders MsC Suzanne Satterfield MD DrPH Steve Cummings MD Jane A. Cauley DrPH Tamara Harris MD MS Alison J. Huang MD MAS Health ABC Study 《Journal of the American Geriatrics Society》2017,65(1):42-50