Tumour frequency in autopsy cases. V. The leucoses (author's transl)]

The analysis is based on the catalogue of neoplasms notifiable in the German Democratic Republic (ICD-Code Nrs. 140-209, 210.2, 211.3, 211.9, 225, 226.2, 226.3, 253.2, 702, 757.2). At the Medical Academy of Erfurt 22155 autopsies (12212 males, 9943 females) of adults (15 years and upwards) were registered in the period from 1950 to 1966. Among them 322 leucoses (1,5% of autopsies and 4,3% of malignant tumours) were observed. The cases are distributed among 175 males (1,4% of males) and 147 females (1,5% of females). There is no sex difference in frequency. Age and sex distribution are presented for all leucoses and for chronic lymphatic leucosis, chronic myeloic leucosis and acute leucoses.     

Tumor frequency in autopsy cases. I: frequency, age and sex distribution, primary localization (author's transl)]

The analysis is based on the catalogue of neoplasms notifiable in the German Democratic Republic (ICD-Code Nrs. 140-209, 210.2, 211.3, 211.9, 225, 226.2, 226.3, 253.0, 253.2, 702, 757.2). At the Medical Academy of Erfurt 22,155 autopsies (12,212 males, 9,943 females) of adults (15 years and upwards) were registrated in the period from 1950 to 1966. 7,533 malignant tumours (34.2%) were observed. 99 cases were eliminated because of an unknown localization of the primary tumour. The remaining 7,442 cases (33.6%) are distributed among 3,987 males (326% of males) and 3,455 females (34,7% of females). The frequency difference based on the autopsy frequency of males or females, is distinct. Malignant epithelial tumours were observed in 5,559 cases (253% of autopsies; 752% of malignant tumours); 2,945 males and 2,654 females. The frequency difference also is distinct. Malignant nonepithelial tumours were observed in 1,843 cases (83% of autopsies, 24.8% of malignant tumours); 1,042 males and 801 females. There is no difference in frequency. Age and sex distribution as well as the relative curve of age distribution (Dormanns 1933) are presented for all the tumours, epithelial and nonepithelial neoplasms. The frequency of primary tumour-localization is reported for males and females, too. In males the frequency is in the following order: lung, stomach, hemopoetic-lymphatic system, colon and central nervous system; in females: sex organs (without mamma), stomach, colon, hemopoetic-lymphatic system and central nervous system.     

Tumouer frequency in autopsy cases. III. The carcinoma of the lung (author's transl)]

The analysis is based on the catalogue of neoplasms notifiable in the German Democratic Republic (IDC-Code Nrs. 140-209, 210.2, 211.3, 211.9, 225, 226.2, 226.3, 253.0, 702, 757.2). At the Medical Academy of Erfurt 22 155 autopsies (12 212 males, 9 943 females) of adults (15 years and upwards were registrated in the period from 1950 to 1966. Among them 1 168 carcinomas of the lung (5.3% of autopsies and 15.2% of all tumours) were observed. The cases are distributed among 1010 males (8.3% of males) and 158 females (1.6% of females). The frequency difference is distinct. Age and sex distribution, frequency and localization of metastases are presented.     

Tumour frequency in autopsy cases. II. The malignant tumours of the stomach (author's transl)]

The analysis is based on the catalogue of neoplasms notifiable in the German Democratic Republic (ICD-Code Nrs. 140--209, 210.2, 211.3, 211.9, 225, 226.2, 226.3, 253.0, 253.2, 702, 757.2). At the Medical Academy of Erfurt 22255 autopsies (12212 males, 9943 females) of adults (15 years and upwards) were registrated in the period from 1950 to 1966. 1153 malignant tumors of the stomach (15.5% of autopsies and 5.2% of all tumors) were observed. The cases are distributed among 1129 epithelial and 24 mesenchymal malignant tumors. Malignant epithelial tumours of the stomach were observed in 1129 cases (5.1% of autopsies and 75.2% of all tumours); 713 males and 416 females. The frequency difference is distinct. Malignant mesenchymal tumours of the stomach were observed in 24 cases (0.1% of autopies and 0.3% of all tumours); 14 males and 10 females. Their is no difference in frequency. Age distribution, sex distribution, frequency and localization of metastases are presented. At least the agreement of clinical diagnoses and pathological findings is discussed.     

Tumour frequency in autopsy cases. IV. The malignant tumours of the kidney (author's transl)]

The analysis is based on the catalogue of neoplasms notifiable in the German Democratic Republic (ICD-Code Nrs. 140-209, 210.2, 211.3, 211.9, 225, 226.2, 226.3, 253.0, 253.2, 702, 757.2). At the Medical Academy of Erfurt 22,155 autopsies (12,212 males, 9,943 females) of adults (15 years and upwards) were performed in the period from 1950 to 1966. Among them 186 malignant tumours of the kidney (177 carcinomas, 9 sarcomas) were observed. The cases are distributed among 126 males (1% of males) and 60 females (0.6% of females). The frequency difference is not distinct. Age and sex distribution, frequency and localization of metastases as well as the histologic classification are presented.     

Production of advanced coronary atherosclerosis, myocardial infarction and "sudden death" in swine

The purpose of this study was to develop a model in swine for advanced coronary atherosclerosis and myocardial infarction. The approach was to combine a number of techniques that were thought to induce the development of atherosclerosis, including high-fat, high-cholesterol diets plus propylthiouracil and X-irradiation to the precordial region. The dose of X-irradiation that was used produced no significant changes by itself, but seemed only to enhance the effect of atherogenic diets.     

Pathological evaluation of coronary lesions in cases of cardiac rupture during acute myocardial infarction: An autopsy study of 148 out-of-hospital sudden death cases

We pathologically evaluated coronary artery lesions of left ventricular ruptures during acute myocardial infarctions (148 sudden out-of-hospital death cases; 93 men and 55 women; age range 42–94 years; mean age 68.9 years; 143 atherosclerotic and 5 non-atherosclerotic lesions). Among the 143 hearts with atherosclerotic coronary lesions, three-vessel disease was most frequent, and plaque rupture or erosion and occlusive thrombus were identified in most cases. Ages of the main component of the occlusive thrombus in the culprit coronary artery corresponded histopathologically to those of myocardial infarction. One of the most outstanding features in this pathological study is that acute thrombus in the culprit coronary artery was identified morphologically in most of the cases with advanced myocardial infarction (3 or more days). On the other hand, in cases of fresh myocardial infarction, a preceding mural non-occlusive organizing thrombus was observed mostly underneath the main component of the thrombus. It is suggested that, in most cases, cardiac rupture during acute myocardial infarction occurs at the time of a new ischemic event caused by a new thrombotic coronary lesion.