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1.
目的:对比丙泊酚单用及七氟醚复合丙泊酚维持麻醉在老年二尖瓣置换术中的价值,观察不同方案对患者心肌损伤的影响,指导老年二尖瓣置换手术麻醉维持药物的选择.方法:收集2018年3月 ~2019年12月本院接受二尖瓣置换术老年患者(76例)病历资料,进行回顾性分析.其中,单用丙泊酚[1.5~2μg/ml(血浆靶控浓度)输注]维...  相似文献   

2.
目的 观察七氟醚、丙泊酚两种药物分别用于老年患者全身麻醉诱导对血流动力学的影响.方法 选择期腹部手术患者80例(2008年4月至2009年9月).年龄:65~80岁,ASA Ⅰ- Ⅱ级,男、女不限.随机分为两组:A组40例采用芬太尼、七氟醚、琥珀胆碱诱导、气管插管全身麻醉;B组40例采用芬太尼、丙泊酚、琥珀胆碱诱导、气管插管全身麻醉.术中监测并记录诱导前(T0)、气管插管即刻(T1)、气管插管后1 min(T2)各时间点的心率(HR)、平均上肢动脉压(NBP).结果 血流动力学:A组T0点与T1、T2、各点相比HR、NBP变化较小.B组:T0点与T1、T2、各点相比HR、NBP变化较大.两组相比:P<0.05,差异有统计学意义.结论 七氟醚用于老年患者的全身麻醉诱导具有血流动力学稳定,可控性强等优点,值得在临床推广应用.  相似文献   

3.
目的 通过对七氟醚复合丙泊酚麻醉在小儿手术应用中的临床观察,探讨适合小儿手术的麻醉方式.方法 30例择期手术的患儿随机分为Ⅰ、Ⅱ两组,Ⅰ组以七氟醚吸入诱导并维持麻醉,Ⅱ组行氯胺酮基础麻醉并在术中间断静脉推注氯胺酮1~2mg/kg来维持和加深麻醉.两组患儿术中给予丙泊酚1mg/(kg·h)静脉输注.记录诱导后(T1),手术切皮时(T2)和手术结束时(T3)的spO2、HR,Bp值和惠儿的苏醒时间,并观察术后恶心、呕吐、尿潴留、谵妄躁动等不良反应的发生率.结果 两组患儿各时点的spO2、HR和Bp值的差异均无统计学意义(P>O.O5),Ⅰ组患儿术后苏醒时间较Ⅱ组明显缩短(P〈O.0 5),谵妄发生率显著低于Ⅱ组(P〈O.05).结论 七氟醚复合丙泊酚麻醉缩短了苏醒时间,降低了术中躁动和术后谵妄的发生率,从安全性和有效性上都不失为一种适合小儿手术的麻醉方式.  相似文献   

4.
目的:观察不同麻醉方案对风湿性心脏病患者进行二尖瓣置换手术的影响.方法:选择2019年3月—2020年10月我院收治的98例风湿性心脏病患者作为研究对象,所有患者均行二尖瓣置换术,随机将所有患者分为丙泊酚组和七氟醚组,各49例,七氟醚组患者全程吸入七氟醚进行麻醉,丙泊酚组患者采用丙泊酚全程把控输注麻醉,比较两组患者麻醉...  相似文献   

5.
目的 探析老年冠心病患者胃癌根治术中七氟醚与丙泊酚麻醉的心肌保护作用.方法 入选2013年3月至2014年3月我院冠心病合并胃癌老年患者86例,所有患者均进行胃癌根治术,按麻醉方式的不同分为实验组和对照组,实验组进行七氟醚复合瑞芬太尼麻醉,对照组进行丙泊酚复合瑞芬太尼麻醉,比较两组患者不同时间点的血清肌酸激酶同工酶(CK-MB)及血清心肌肌钙蛋白Ⅰ(cTnⅠ)水平.结果 实验组患者术后6、12、24 h的CK-MB、cTnⅠ水平显著低于对照组,差异有统计学意义(P<0.01).结论 老年冠心病患者胃癌根治术进行七氟醚与瑞芬太尼复合麻醉保护心肌效果更强,值得临床推广.  相似文献   

6.
目的:探讨七氟醚复合丙泊酚用于无痛肠镜检查的麻醉效果及安全性。方法120例ASAⅠ~Ⅱ级在门诊做无痛肠镜检查的患者随机分成两组,每组均为60例, A组为芬太尼+丙泊酚组, B组为七氟醚+丙泊酚组,记录两组受检者的心率(HR)、平均动脉压(MAP)、脉搏血氧饱和度(SpO2)以及肠镜操作时间、苏醒时间和丙泊酚的总量等并进行统计学比较。结果两组患者在无痛肠镜检查前后,其HR、MAP、SpO2指标的差异不具有统计学意义(P〉0.05),A组患者由于在检测过程中持续性的使用丙泊酚,其丙泊酚用量为269.56 mg,明显高于B组患者丙泊酚用量(P〈0.05),另外, A组患者的平均手术时间为(8.26±2.05)min,明显低于对照组数据结果(P〈0.05)。结论七氟醚复合丙泊酚用于无痛肠镜检查具有满意的麻醉效果及较高的用药安全性。  相似文献   

7.
目的:探讨七氟醚与丙泊酚复合麻醉对老年骨科患者术后认知功能的影响。方法:选择在某院接受骨科手术治疗的老年患者90例,按麻醉给药方式不同分为P组(丙泊酚复合麻醉组)和S组(七氟醚复合麻醉组),每组各45例,手术过程中记录患者手术时间、麻醉时间、出血量、术后睁眼时间、拔管时间等一般手术情况,并采用简易精神状态量表(MMSE)对两组患者术前1d、术后1d,2d,3d的认知功能进行比较。结果:两组患者一般手术情况(手术时间、麻醉时间、出血量、睁眼时间、拔管时间)比较差异不显著(P>0.05),术后两组患者MMSE评分均出现先下降后上升的趋势,术后第2dS组患者MMSE评分显著高于P组,组间比较差异显著(P<0.05)。结论:七氟醚与丙泊酚复合麻醉可降低患者的认知功能,但术后均可逐步恢复,其中七氟醚复合麻醉恢复患者认知功能的时间短于丙泊酚复合麻醉,效果明显,值得临床推广使用。  相似文献   

8.
杜秋 《现代临床医学》2012,38(3):190-191
目的:探讨丙泊酚复合七氟醚麻醉在纤维支气管镜检术中的应用.方法:将40例纤维支气管镜检查患者随机分为2组,对照组采用全静脉麻醉,观察组采用丙泊酚复合七氟醚麻醉.观察2组血压、心率和SpO2的变化情况.结果:观察组SBP明显降低而术后SpO2没有明显下降.结论:丙泊酚复合七氟醚麻醉用于纤维支气管镜检查临床效果良好,不良反应少,值得临床推广.  相似文献   

9.
七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果   总被引:2,自引:0,他引:2  
目的观察七氟醚复合丙泊酚在小儿气道异物取出术中的麻醉效果。方法选择符合美国麻醉学会制定的Ⅰ-Ⅱ级标准、年龄1—4岁、行气管异物取出术小儿60例,随机数字表法分为七氟醚组和氯胺酮组,每组30例。七氟醚组采用吸入七氟醚诱导麻醉,术中维持药物选用丙泊酚1.5mg/(kg·h)微泵持续注入。间断吸入七氟醚;氯胺酮组静脉注射咪达唑仑0.1mg/kg和氯胺酮1.5mg/kg诱导麻醉,术中麻醉深度不足时分次静脉注射氯胺酮1.5mg/kg至麻醉满意。记录诱导前(T0)、麻醉诱导后术前1min(T2)、插入支气管镜时(T2)、拔支气管镜时(T3)、清醒时(T4)血压、心率及血氧饱和度。记录手术时间、苏醒时间和术中医生满意度,观察术中和术后患儿是否有支气管痉挛、呕吐、呼吸道梗阻、舌后坠等并发症。结果2组患儿T2时收缩压、心率较T0时明显升高。七氟醚组患儿T1时收缩压、心率较T0时明显降低;2组患儿血氧饱和度T1-T4各时段均较T0时明显升高;七氟醚组患儿苏醒时间显著快于氯胺酮组;七氟醚组患儿医生满意度较氯胺酮组高;术后氯胺酮组患儿舌后坠发生率明显高于七氟醚组,差异有统计学意义(P〈0.05)。2组患儿T0~T4各时段舒张压、血氧饱和度差异均无统计学意义(P〉0.05)。结论七氟醚复合丙泊酚在小儿气道异物取出术中能提供良好的手术条件,术中麻醉平稳,术后患儿苏醒快且苏醒质量较高。  相似文献   

10.
目的:探讨丙泊酚复合七氟醚麻醉在小儿纤维支气管镜检术中的应用效果。方法选取本院2010年1月-2013年6月184例应用纤维支气管镜检查患儿,按照数字抽取原则分为研究组与对照组,对照组应用静脉全身性麻醉,研究组患儿则应用丙泊酚联合七氟醚麻醉,分析比较两组患者麻醉效果及检测指标变化情况。结果研究组患儿手术后SBP显著下降,手术前后差异有统计学意义(P〈0.05);对照组术后SpO2减少,手术前后差异有统计学意义(P〈0.05)。结论丙泊酚复合七氟醚麻醉用于小儿纤维支气管镜检查效果良好,具有较高安全性,临床推广应用价值较高。  相似文献   

11.
孙鼐 《中国实用医药》2011,6(31):182-183
目的探讨丙泊酚复合七氟醚麻醉在纤维支气管镜检术中的应用及临床效果。方法 2010年05月至2011年05月期间,我院诊治的40例纤维支气管镜检查患者,随机分为观察组(丙泊酚复合七氟醚麻醉)和对照组(全静脉麻醉),每组各20例,对其病例进行回顾性分析。结果与对照组SBP(111.1±20.5)相比,观察组的SBP(96.5±15.7)明显降低,P<0.05,差异具有统计学意义;观察组术后SpO2与术前SpO2(98.5±0.7)相比,没有明显下降(98.1±0.4),P>0.05。结论对于纤维支气管镜检查,丙泊酚复合七氟醚麻醉的临床效果良好,而且不良反应少,值得临床广泛推广。  相似文献   

12.
目的分析丙泊酚复合七氟醚与全凭七氟醚对小儿苏醒期躁动的效果。方法选取我院2015年6月至2016年6月收治的手术患者42例,随机分为实验组和对照组,每组21例。对照组患者实施七氟醚进行麻醉,实验组患者实施丙泊酚复合七氟醚进行麻醉,对比分析两组患者苏醒期躁动情况。结果实验组患者清醒时间(23.2±4.7)min、躁动4例,躁动时间15min以上者3例、平均躁动评分(1.56±0.22)分;对照组患者清醒时间(15.6±3.9)min、躁动12例,躁动时间15 min以上者10例、平均躁动评分(2.65±0.43)分,差异具有统计学意义(P<0.05)。结论丙泊酚复合七氟醚可以有效降低小儿苏醒期的躁动情况,提升患者的清醒时间,值得临床广泛推广和应用。  相似文献   

13.
Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.  相似文献   

14.
Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.  相似文献   

15.
Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.  相似文献   

16.
Objective To observe the anesthetic effect of sevoflurane combined with propofol total general anaesthesia in children undergoing tracheal foreign body removal. Methods Sixty patients aged from 1 to 4 years admitted for tracheal foreign body removal were randomly divided into two groups : sevoflurane group (n = 30) and ketamine group (n = 30). In the sevoflurane group, anaesthesia was induced and maintained with inhalation of sevoflurane and propofol [1.5 mg/(kg · h)] was administered continuously for anesthesia maintenance by micro-pump during operation. The ketamine group were pre-medicated with ketamine 6 mg/kg i. m for sedation, then an-aesthesia was induced with midazolam 0.1 mg/kg and ketamine 1.5 mg/kg i. v and was maintained with intravenous bolus of ketamine. Systolic blood pressure(SBP), Diastolic blood pressure(DBP) ,heart rate(HR) and saturation of percutaneous oxygen(SPO2) were monitored in both groups before anaesthesia inducation (T0) , after anaesthesia inducation and before operation (T1), at the time point of bronchial endoscopy(T2) ,endoscope remoral (T3) ,con-sciousness recovery(T4). The operation condition was evaluated by surgeons, and the incidence of bronchial spasm, glossal drop, nausea and vomiting were recorded both during operation and after operation. Results The SBP and HR increased at the time point of bronchial endoscopy in two groups and decreased after anaesthesia inducation in aevoflurane group. The SPO2 increased in two group after anaesthesia inducation. Compared with ketamine group, the time of consciousness recovery was shorter markedly in sevoflurane group. The occurrence of postoperative glossal drop was higher in ketamine group. Conclusion Sevoflurane combined with propofol is safe and effective during general anaesthesia of children undergoing tracheal foreign body removal.  相似文献   

17.
丙泊酚复合七氟醚麻醉在小儿纤维支气管镜检术中的应用   总被引:2,自引:0,他引:2  
陈明  金利民  余凌 《医药导报》2010,29(2):212-213
目的探讨丙泊酚静脉复合七氟醚吸入麻醉在小儿纤维支气管镜检术中的应用。方法将符合入选标准的需行纤维支气管镜检患儿49例随机分为A组22例和B组27例。所有患儿术前6 h禁食水,术前静脉给予盐酸戊乙奎醚0.01 mg&#8226;kg 1。进入手术室后监测患儿血氧饱和度(SpO2)、心电图及血压。A组给予丙泊酚静脉复合七氟醚吸入麻醉,静脉注射地塞米松0.3 mg&#8226;kg 1,丙泊酚2 mg&#8226;kg 1诱导,然后吸入8%七氟醚,氧流量2 L&#8226;min 1,4~5 min后患儿下颌及四肢松弛,利用鼻给氧长塑料管与气管导管接头接到麻醉机螺纹管开口端,另一端接一个用7号头皮针自制吸氧管放入患儿鼻孔内给氧并给予七氟醚开放吸入维持麻醉,七氟醚8%,氧流量根据年龄调整为2~3 L&#8226;min 1;B组采用全凭静脉麻醉,静脉注射地塞米松0.3 mg&#8226;kg 1,丙泊酚1~2 mg&#8226;kg 1,咪达唑仑0.1~0.2 mg&#8226;kg 1,氯胺酮1~2 mg&#8226;kg 1诱导。静脉泵给予丙泊酚6 mg&#8226;kg 1&#8226;h 1输注维持。两组患儿均在诱导入睡后用1%利多卡因喷雾咽喉进行表面麻醉,纤支镜从另外一侧鼻腔插入。入室至苏醒期间连续观察SpO2、心率(HR)、收缩压(SBP)、舒张压(DBP)变化及声门开放,术中窒息、呛咳、术后恶心呕吐及苏醒时间。结果B 组置镜后1 min(M1)、置镜后5 min(M2)、退镜前(M3)、苏醒时(M4)SpO2与给药前(M0)比较有所下降(P<0.05),A组无明显变化。A 组SBP在置镜后均有不同程度下降,与B组比较,差异有显著性(P<0.05)。A组苏醒时间较B组有所缩短(P<0.05)。结论丙泊酚静脉复合七氟醚吸入麻醉安全,不良反应少,是小儿纤维支气管镜检查的一种理想的麻醉方法。  相似文献   

18.
七氟醚与丙泊酚在神经外科麻醉恢复期效果比较   总被引:5,自引:1,他引:5  
目的 研究七氟醚、丙泊酚对神经外科长时间麻醉维持后苏醒时间等的影响.方法 将50例神经外科择期手术患者随机分为七氟醚组和丙泊酚组各25例,麻醉维持首先根据BIS监测来调节七氟醚的吸入浓度或丙泊酚的静脉靶控浓度,使BIS维持在45~55之间,然后根据平均动脉压调节瑞芬太尼的输注速率,手术结束后停止麻醉药.观察两组的拔管时间、苏醒时间、定向力恢复时间、简单神经病学评估恢复时间等.结果 七氟醚麻醉后拔管时间、苏醒时间、简单神经病学评估恢复时间均明显小于丙泊酚组(均P<0.05),而定向力恢复时间,术后呕吐、寒战发生率差异无显著性.结论 七氟醚和丙泊酚都适合于需要快速苏醒的神经外科麻醉,其中七氟醚苏醒更迅速.  相似文献   

19.
目的探究七氟醚或丙泊酚复合瑞芬太尼麻醉在腹腔镜胆囊切除术患者中的麻醉效果。方法从我院2016年4月至2017年4月的行腹腔镜胆囊切除术患者中选取90例,分为观察组47例和对照组43例,予对照组丙泊酚和瑞芬太尼麻醉,观察组使用七氟醚和瑞芬太尼麻醉,对两组麻醉效果进行观察。结果观察组T_1收缩压、舒张压低于T_0,对照组T_1收缩压、舒张压及心率高于T_0,观察组T_1收缩压、心率低于对照组(P <0.05);观察组恢复自主呼吸时间、拔管时间及睁眼时间均短于对照组(P <0.05)。结论使用七氟醚或丙泊酚复合瑞芬太尼麻醉效果均较佳,但七氟醚复合瑞芬太尼的应激反应较小,血流动力学影响小。  相似文献   

20.
钟成跃  王灿  魏海利 《安徽医药》2019,40(10):1146-1148
目的 探讨七氟醚对风湿性心脏病患者心内直视瓣膜置换术后认知功能的影响及作用机制。方法 选取中国人民解放军联勤保障部队第988医院2017年7月至2019年1月手术治疗的风湿性心脏病患者108例,根据麻醉方案不同分为两组(S组56例、P组52例)。P组给予丙泊酚全程靶控输注,S组给予七氟醚全程吸入麻醉。观察并比较两组患者术前1 d、术后3 d的认知功能(MMSE评分)及两组不同时间点[术前(T1)、体外循环前(T2)、体外循环后(T3)、术毕(T4)]血流动力学指标[平均动脉压(MAP)、中心静脉压(CVP)、心率(HR)]及不同时间点[麻醉诱导前(t1)及主动脉开放2 h(t2)、6 h(t3)、12 h(t4)、24 h(t5)]心肌酶谱指标[心肌肌钙蛋白I(cTnI)、丙二醛(MDA)、肌酸磷酸激酶同工酶(CK-MB)、超氧化物歧化酶(SOD)]和术后导管拔除时间、心脏自主复跳情况、心肌收缩力情况。结果 两组术前MMSE评分差异无统计学意义;S组手术前后MMSE评分差值低于P组,差异有统计学意义(P<0.05);两组患者T1、T2、T3、T4时间点MAP、HR、CVP比较,差异均无统计学意义(P>0.05);S组t2、t3、t4、t5时间点cTnI水平低于P组,t3、t4、t5时间点CK-MB水平低于P组,t2、t3、t4时间点SOD水平高于P组,MDA水平低于P组,差异均有统计学意义(P<0.05);S组导管拔除时间短于P组,心脏自主复跳率高于P组,心肌收缩力评分低于P组,差异均无统计学意义(P>0.05)。结论 七氟醚全程吸入麻醉有助于改善风湿性心脏病患者认知功能,其作用可能与抑制cTnI、CK-MB、MDA水平及升高SOD水平有关。  相似文献   

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