INFECTION VERSUS DISEASE IN SOUTH AMERICAN BLASTOMYCOSIS

ABSTRACT: The mechanism of infection in South American blastomycosis is discussed, and the probability of a mild or asymptomatic form of the disease, regressing spontaneously with subsequent immunity, in persons living in endemic areas. Primary lesions in the oral mucosa or in the skin have not been convincingly shown to occur in paracoccidioidomycosis. Several reports of systemic involvement of many organs with no evidence of skin and mucosal lesions support the theory of pulmonary entry.     

健康人和病人各型舌苔真菌带菌情况调查初报

本文报告对262例病人和102名健康人舌苔真菌带菌情况的调查,其结果显示:舌苔的真菌带菌率分别为白苔70.1%和29.1%,黄苔60.5%和29.7%。在病人中黑苔为83.3%,灰苔为33.3%,其中按菌种计白念珠菌的带菌率为8.4%和2.9%,其他,念球菌为28.2%与6.9%,酵母菌18.3%与11.8%,曲菌7.6%与4.9%,青霉菌2.7%与1.9%,毛霉菌1.2%与1.0%,地丝菌0.4%与0,总带菌率为66.8%与29.4%,两组的差异具有非常明显的统计学意义(P<0.001)。白念珠菌带菌率白苔高于黄苔,这与口腔内的pH值及病人的年龄相关。     

INVASION OF THE SKIN BY FILAMENTOUS NON-DERMATOPHYTE FUNGI

SUMMARY. —Four cases of invasion of the glabrous skin by filamentous, non-dermatophyte fungi are described. Aspergillus niger was found in the toewebs of 1 patient and Allescheria boydii in those of another. Fusarium solani and F. oxysporum var. redolens were colonising necrotic skin in 2 diabetic patients.
It was concluded that in all these cases the fungal invasion was purely saprophytic in nature. The difficulty of discriminating between contamination and saprophytic invasion of the skin by non-dermatophytes is discussed and criteria for making the distinction are suggested.     

GEOGRAPHICAL PATTERN OF PEMPHIGUS IN NORTH INDIA

A clinical analysis of 70 patients suffering from various types of pemphigus is presented. It revealed a characteristic morphology, and occurrence in a relatively younger age group. Sex had hardly any impact on the disease. Pemphigus vulgaris constituted the largest group. Corticosteroids were the mainstay of its treatment although both lower initial and maintenance dosages were needed in our patients in contrast to those of the standard literature.