重度妊娠高血压综合征67例临床分析

目的探讨重度妊娠高血压综合征终止妊娠时机和方式。方法对67例重度妊高征进行回顾性分析,观察重度妊高征及终止妊娠的时机和方式对母婴的影响。结果重度子痫前期54例,产前子痫10例,产时子痫2例,产后子痫1例,母亲全部存活,剖宫产率74．63％,新生儿窒息率34．33％,围产儿死亡率11．69％。结论重度妊高征除药物治疗外,适时剖宫产是抢救重度妊高症的一种有效手段。     

重度妊娠高血压疾病终止妊娠时机及分娩方式的探讨

目的：探讨重度妊娠高血压疾病终止妊娠的时机和分娩方式。方法：对86例重度妊娠高血压疾病进行了回顾性分析,比较不同孕周终止妊娠及不同分娩方式的孕产妇并发症发生率,新生儿的窒息率和死亡率。结果：重度妊娠高血压疾病剖宫产围生儿死亡率（4．44％）、孕产妇并发症发生率（17．78％）明显降低（P〈0．05）;≤33周分娩的新生儿窒息率（62．50％）、围生儿死亡率（50．00％）明显升高（P〈0．05）,34-36周与≥37周差异无显著性（P〉0．OS）。结论：重度妊娠高血压疾病患者,在促胎肺成熟治疗后于孕34周终止妊娠,终止妊娠的方式首选剖宫产。     

30例重度妊娠高血压综合征临床分析

目的 探讨重度妊娠高血压综合征患者终止妊娠的时机与方式.方法 回顾性分析重度妊高征终止妊娠的时机与方式及其对母婴结局的影响.结果 30例产妇中先兆子痫11例,产前子痫2例,产后子痫1例,HELLP综合征3例,弥散性血管内凝血（DIC）并产后出血4例.早产12例,1例因胎盘早剥胎死宫内,新生儿窒息4例.结论 在解痉与镇静的基础上,及时终止妊娠,可减少母婴并发症.     

重度妊娠高血压综合征终止妊娠时机及方式的探讨

重度妊娠高血压综合征（妊高征）除药物治疗外,适时终止妊娠是抢救重度妊高征的一种手段,选择最佳方式适时终止妊娠,降低围生病率及母婴死亡率是当前学者们关注的问题,现将我们收治的25例患者临床资料总结如下,以探讨终止妊娠的时机和方法.     

妊娠高血压综合征的产科治疗

目的探讨妊娠高血压综合征终止妊娠的时机、方式和对母婴的影响。方法选择76例妊娠高血压征为研究对象，观察新生儿体重、剖宫产率、孕产妇并发症和母婴预后情况。结果总剖宫产率为78．9％。无一例死亡；低体重儿发生率为24．4％，重度妊高征伴有低体重儿发生率为25．4％，明显高于轻、中度妊高征；孕产妇并发症中，胎盘早剥2例，心衰2例，肾衰3例，产后出血11例；母婴预后良好。结论适时终止妊娠是产科治疗妊娠高血压综合征的主要手段，终止妊娠的方式首选剖宫产。     

妊娠高血压综合征130例分娩时机和结局临床分析

目的探讨妊娠高血压综合征终止妊娠的时机和分娩结局。方法对130例妊娠高血压综合征进行回顾性分析和研究，观察妊娠高血压综合征对母儿的影响。结果产妇死亡2例，围产儿死亡8例，早产儿及低体重儿发病率高。结论应加强孕期保健，及早治疗妊娠高血压综合征，选择适当的时机和方式终止妊娠．降低母婴各种并发症的发生率。     

妊娠高血压综合征64例产科处理临床分析

目的探讨妊娠高血压综合征终止妊娠的时机和方式，对母婴的影响。方法对64例妊娠高血压综合征进行了回顾性分析，观察新生儿的窒息率和死亡率、剖宫产率。结果轻度妊高征26例，先兆子痫21例，产前子痫8例，产时子痫9例。母亲全部存活。剖宫产率72％，新生机窒息率32％，围产儿死亡率1.6％。结论产科治疗妊娠高血压综合征适时终止妊娠是极主要的手段，终止妊娠的方式首先剖宫产。     

重度妊娠高血压综合征的临床分析

目的:探讨重度妊娠高血压综合征的临床特点和有效治疗方案.方法:通过对45例重度妊娠高血压综合征病例进行回顾分析,总结重度妊高征的药物治疗方法及观察终止妊娠时机和方式对母儿的影响.结果:先兆子痫15例,产前子痫3例,产后子痫1例,母亲全部存活,均为剖宫产,新生儿窒息2例,围生儿死亡1例.结论:妊娠高血压综合征患者应认真做好产前检查,在解痉、降压、镇静为原则积极的治疗基础上,适时采用剖宫产终止妊娠是抢救重度妊娠高血压综合征的有效手段.     

妊娠高血压疾病患者终止妊娠时机及分娩方式的临床研究

目的探析妊娠高血压疾病患者终止妊娠时机及分娩方式。方法选取我院于2014年1月至2016年8月收治75例妊娠期高血压患者为研究对象,对所有患者的各项临床资料、妊娠终止时间、分娩方式进行回顾性分析。结果 <34周终止妊娠的产妇并发症、围生儿病死率、新生儿窒息发生率均明显高于34~36周及36周以上(P<0.05);阴道分娩的产妇并发症、围生儿病死率、新生儿窒息发生率均明显高于剖宫产分娩(P<0.05)。结论对于妊娠高血压疾病患者而言,在34周以后终止妊娠可降低新生儿病死率和窒息发生率,给予患者有效治疗可延长其妊娠时间。在分娩方式的选择上,要根据妊娠期高血压患者的具体情况,尽可能选择剖宫产分娩,更有利于降低各项并发症发生率,改善母婴结局。     

妊高征81例临床诊疗分析

目的探讨妊娠高血压综合征(简称妊高征)终止妊娠的时机、方式和对母婴的影响。方法选择81例妊高征患者为研究对象,观察新生儿体重、剖宫产率、孕产妇并发症和母婴预后情况。结果总剖宫产率75.31%;无一例死亡;低体重儿发生率为25.93%,重度妊高征伴有低体重儿发生率为26.3%,明显高于轻、中度妊高征;孕产妇并发症中,胎盘早剥1例,心衰3例,肾衰4例,产后出血9例;母婴预后良好。结论适时终止妊娠是产科治疗妊娠高血压综合征的主要手段,终止妊娠的方式首选剖宫产。     

重度子痫前期终止妊娠时机的研究

目的:为了降低围产期母婴并发症,探讨重度子痫前期终止妊娠的时机。方法:回顾分析重度子痫前期302例临床资料。结果:①早发型及晚发型两型重度子痫前期的孕妇年龄、孕产次、收缩压、舒张压比较,型间无显著性差异,两型间终止妊娠时间比较有极显著性差异,两型间保守治疗时间比较型间有极显著性差异,两型间围产儿死亡率比较有极显著性差异;②随着终止妊娠时孕周的增加早期新生儿死亡率下降,但死胎发生率增加;③随着终止妊娠时孕周的增加孕产妇发生严重并发症的比率增加,且并发症累及孕妇脏器个数的增加,围产儿死亡率随之增加。结论:无严重并发症的早发型重度子痫前期患者宜在期待治疗至32~32+6W时终止妊娠。接近孕足月的晚发型重度子痫前期患者经药物治疗控制病情后应立即终止妊娠。重度子痫前期并发严重并发症者无论胎儿成熟与否均需在积极治疗并发症同时立即剖宫产终止妊娠。     

自然分娩与干预性分娩对妊高征围产儿的影响

妊高症(PIH)是孕产妇及围产儿死亡的主要原因。恰当的分娩方式与围产儿的预后关系密切。对62例PIH及围产儿进行回顾性分析。结果:1.适时干预性终止妊娠能使孕妇病情迅速好转,并使胎儿尽早脱离宫内不良环境,减少胎死宫内的发生。2.在重度PIH。干预性分娩者明显高于自然分娩组,围产儿预后明显优于自然分娩组。3.重度PIH宜选用剖宫产终止妊娠。4.轻、中度PIH患者孕37周后,应采取干预性分娩,可提高围产儿成活率及生存质量。     

孕晚期孕妇钙元素含量对新生儿出生状况的影响

目的：探讨微量元素钙含量对新生儿出生状况的影响。方法：采用原子吸收光谱法测定816例孕晚期孕妇血清中钙元素的含量．并对所有新生儿进行体重、身长的测量及Apgar评分。结果：孕晚期孕妇钙元素缺乏者占59．80％．母钙元素正常者其新生儿出生时的体重高于母钙元素缺乏者新生儿出生时的体重,两者间差异有统计学意义。钙元素缺乏者其新生儿出生时的Apgar评分中,〈8分的人数构成高于钙元素正常者的新生儿人数．两者间差异有统计学意义。结论：孕晚期孕妇钙元素含量对新生儿出生状况有一定影响。孕妇在妊娠期间应加强营养,增加体内钙元素的含量和活性．以保证母婴健康。     

社区1124例高危孕妇管理及结局分析

目的分析社区常见高危因素及后果,为进一步提高高危妊娠管理水平积累经验。方法对社区2008年1月1日～2010年12月31日分娩的1124例高危妊娠产妇资料统计分析。结果社区高危妊娠发生率34.18%,剖宫产率64.02%,前3位高危因素分别为怀孕≥3次、年龄≥35岁、瘢痕子宫,两种以上高危因素占43.24%,动态高危妊娠转归率67.76%。高危妊娠早产率、新生儿窒息、死胎死产、新生儿死亡率明显高于正常妊娠,出生缺陷控制在较低水平。结论高危妊娠对妊娠结局有不良影响。重视高危因素的筛查和处理,加强高危妊娠的跟踪管理是保证母婴安全、减少不良结局的有效措施。     

Drug use in pregnancy at a referral and district hospital in northern India

This is the Indian counterpart of the co-operative study on drug use in pregnancy carried out under the auspices of WHO–EURO and co-ordinated by the Mario Negri Institute, Milan (Italy). In all 1497 pregnant women were interviewed (1000 from the referral hospital and 497 from the city hospital) to collect the information. The mean age of the mothers was 25 years; 50% were hospitalized on the day of delivery; 50% of the deliveries were normal and the other 50% were assisted or operative. Congential malformations were seen in 2.0% of the newborns. The drugs taken throughout pregnancy were tetanus toxoid (TT) and nutritional supplements (iron, folic acid, calcium and multivitamins) and constituted the largest group (35%). Women on chronic therapy for medical or obstetrical problems related to the pregnancy were 1%. Overall 30.5% of the women received drugs during hospitalization for delivery. Local and general anaesthetics and oxytocics were the most used during this period. As the rate of operative deliveries was high 33% of the women received antimicrobials, analgesics and sedatives during puerperium. Nutritional supplements were used extensively during current or planned breast-feeding. The routine use of iron supplements in pregnancy and the high rate of operative deliveries seemed to contrast to other countries which participated in this study.     

妊娠中晚期高危妊娠胎心率电子监护异常分析

目的 评价妊娠中晚期实施胎心监护的临床效果和意义.方法 对福建省妇幼保健院收治的596例实施中晚期胎心监护的高危孕妇其胎心电子监护结果进行分析,并与121例外院转入未实施中晚期胎心监护的高危妊娠孕妇比较其妊娠结局.结果 两组人群基本人群社会资料构成一致,中晚期妊娠胎心率从32周到36周逐渐下降趋势.胎心监护异常的高危妊娠孕妇平均胎心率低于胎心监护正常的高危孕妇(P<0.05).实施中晚期胎心监护的高危妊娠产妇其顺娩率和阴道助产率显著高于未实施中晚期胎心监护者(P<0.05).结论 对高危妊娠产妇实施中晚期胎心监护有积极的意义,能够更好保障高危妊娠孕妇的母婴健康,值得推广.     

Ergotamine treatment during pregnancy and a higher rate of low birthweight and preterm birth

AIMS: Previously the association between oral ergotamine treatment during pregnancy and gestational age at delivery, birthweight, the rate of preterm birth and low birthweight has not been studied. METHODS: Newborn infants without congenital abnormalities born to mothers with or without ergotamine treatment during pregnancy were evaluated in the population-based data set of the Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996. RESULTS: Of 38,151 newborn infants with medically recorded gestational age and birth weight, 77 were born to mothers who had received ergotamine treatment during pregnancy. A statistically significant decrease was found in the mean gestational age (0.7 weeks) and birth weight (196 g) among exposed relative to unexposed infants, though these differences were not obstetrically significant. However, there was a significant increase in the proportion of low birthweight newborns (16.4% vs. 5.7%) and preterm births (16.4% vs. 9.2%) after the use of ergotamine during pregnancy. The effect of ergotamine was more obvious in male newborn infants, particularly after treatment in the third trimester. CONCLUSIONS: The association between low birthweight and/or preterm birth and ergotamine treatment may be connected with the effect of ergotamine on the placenta of pregnant women.     

No association between vulvovaginitis-bacterial vaginosis,related drug treatments of pregnant women,and congenital abnormalities in their offspring — A population-based case-control study

The possible association between prospectively and medically recorded vulvovaginitis-bacterial vaginosis (VV-BV) and different congenital abnormalities (CA) has not been studied. The data set of the population-based Hungarian Case-Control Surveillance of Congenital Abnormalities between 1980 and 1996 were evaluated, i.e. 22,843 pregnant women who had newborns or fetuses with congenital abnormality (cases) and 38,151 pregnant women who delivered newborn babies without any congenital abnormality (controls). The main outcome measures were different congenital abnormalities. Of 22,843 cases with CA, 1,536 (6.7%) had mothers with VV-BV, while of 38,151 matched controls without CA, 2,698 (7.1%) had mothers with VV-BV in the second and/or third gestational month of pregnancy. Nearly all pregnant women with VV-BV were treated during pregnancy, but a higher risk for the total group of CAs (adjusted POR with 95% CI: 0.95, 0.89–1.02) or any CA group was not found. In addition, the risk for total CAs was significantly lower in cases born to mothers with VV-BV and appropriate treatment than born to mothers with VV-BV but without treatment. Thus maternal VV-BV needs treatment during pregnancy as well, because it helps reduce the rate of preterm birth without a risk for CAs.     

孕晚期营养素摄入对新生儿出生体重的影响

目的探讨孕晚期营养素摄入状况对新生儿出生体重的影响。方法 1263例孕产妇及其新生儿,对其孕晚期营养摄入情况进行调查,分析孕晚期营养素摄入对新生儿出生体重的影响。结果 1263例孕妇年龄23~34岁,平均年龄(27.1±3.2)岁;孕周38~40周,平均孕周(39.3±0.5)周;分娩方式:阴道分娩1076例,剖宫产187例;共娩出1263例新生儿,均为活胎,男637例,女626例;体重2163~4118 g,平均体重(3233.8±357.0)g;未发生产科并发症及新生儿合并症;低出生体重(LBW)65例(5.15%)、正常体重(NW) 1105例(87.49%)、巨大儿(LBG) 93例(7.36%)。LBW新生儿、NW新生儿、LBG碳水化合物、脂肪、蛋白质、纤维、维生素C(VC)、铁、锌摄入量比较差异具有统计学意义(P<0.05);LBW新生儿、NW新生儿、LBG总热量、维生素A(VA)、维生素B1(VB1)、叶酸、钙摄入量比较差异无统计学意义(P>0.05)。Logistic回归分析显示:孕晚期碳水化合物、蛋白质、铁、锌摄入不足是LBW发生的危险因素,孕晚期碳水化合物、脂肪、锌摄入过多是LBG发生的危险因素。结论孕晚期碳水化合物、脂肪、蛋白质、铁、锌的摄入与新生儿体重密切相关,孕晚期应依据胎儿具体发育情况指导孕妇依据自身情况合理膳食,减少LBW及LBG的发生。     

子痫前期与子痫终止妊娠时机及方式的探讨

目的探讨子痫前期与子痫终止妊娠的时机和方式对母婴的影响。方法对42例患者进行了回顾性分析，观察新生儿的窒息率和死亡率。结果产前子痫5例，产时子痫4例，产后子痫2例，子痫前期30例，母亲全部存活，剖官产率86．70％，新生儿窒息率92．85％，围生儿死亡率5．8％。结论治疗子痫前期与子痫适时终止妊娠是极重要的方法，终止妊娠的方式首选剖宫产。