Heart cardiovascula, vascular disorder

Analysis of surgical treatment for Standford type A aortic dissection; Surgical repair of complex mitral valve regurgitation with the comprehensive application of multiple technique; One stage repair of interrupted aortic arch in 10 patients with associacted cardiac anomalies;The results of surgical treatment of 14 patients underwent repeated tricuspid valve operations; The value of HFABP in the early detection of myocardial injury following open-heart surgery with cardiopulmonary bypass……     

Heart cardiovascula,vascular disorder

<正>209247 Analysis of mortality risk factors in children complicated acute renal dysfunction after congenital cardiac surgery/Huang Jihong(Dept Thorac Cardiovasc Srug,Shanghai Children’s Med Center,Shanghai Jiaotong Univ Med Col,Shanghai 200127)…∥Chin J Thorac Cardiovasc Surg.-2009,25(1).-32~34Objective Peritoneal dialysis offers one of effective methods for treating acute renal dyfunction after congenital cardiac surgery,however the mortality of these patients are still relatively high.The aim of this study was trying to predict the risk factors of mortality risk at initiation of peritoneal dialysis using clinical and laboratory data.Methods From Jun.2006 to Jan.2007,1312 patients with congenital heart disease were treated with cardiac surgery.Twenty seven patients accepted dialysis due to acute renal dysfunction.We analyzed retrospectively the clinical and experimental data obtained befroe starting peritoneal dialysis.Results In 27 children with peritoneal dialysis,there were 13 nonsurvivors(48.1%),14 survivors,there was a significant difference between survivors and nonsurvivors with regard to the viriables parameters such as cardiac troponin I(cTnI),pH,PIP,colloid osmotic pressure(COP),base excess(BE),lactate(Lact),arterial-venous oxygen saturation difference(ΔSO2),and inotropic score(InS).The stepwise regression analysis indicates a multivariate influence of cTnI(P=0.01),pH(P=0.04),PIP(P=0.02),COP(P=0.05) on mortality.Conclusion The variables of cTnI,pH,PIP and COP can help to predict mortality as risk factors at the initiation of peritoneal dialysis.8 refs.     

Heart, cardiovascula, vascular disorder

Experience on surgical treatment of severe aortic valve stenosis： a report of 171 cases,Double-Switch operation in corrected transposition and double outlet right ventricle with atrioventricular discordance,Optimal surgical management for transposition of great arteries with intact ventricular septum in infant older than 21 days,Follow-up of valve operation： a report of 917 cases,Valve replacement and coronary artery bypass grafting on beating heart     

Heart, cardiovascula, vascular disorder

Double switch operation for corrected transposition of the great arteries;Half-turned truncal switch operation for com. plete transposition of the great arteries with ventricular septal defect and pulmonary stenosis and double outlet of right ventricle with pulmonary stenosis;Outcomes after complete repair of tetralogy of fallot in children： a comparison between different age groups;Arterial switch operation for complete transposition of the great arteries with coronary artery from single sinus     

Heart, cardiovascula, vascular disorder

207638 Cli mical study of off-pump plication for left ventricular aneurysm/Sun Hansong(孙寒松,Dept Car- diovasc Surg Cardiovasc Inst Fuwai Hosp,CAMS,Beijing 100037)…∥Chin J Thorac Cardiovasc Surg.-2007 ,23 (3) .-147 ~149 Objective To evaluate the surgical results of off- pumpfor plicationforleft ventricular aneurysm.Methods The study included 34 patients withleft ventricular a- neurysm,who underwentleft ventricular aneurysmectomy and plication on pumpin groupⅠ(17 cases ) andsi mply …     

Heart,cardiovascula,vascular disorder

<正>210307 Early death causes in 2349 patients who receiving heart valve replacement/Chen Haisheng(陈海生,Dept Cardiothorac Surg,Guangzhou Univ Tradit Chin Med 1st Hosp,Guangzhou 525200)…Chin J Thorac Cardiovasc Surg.-2010,26(3).-151～155     

Heart, cardiovascula, vascular disorder

Immune properties of decellular human tissueengineering aortic valves conduits; VEGF165 and angiopoietin-1 synergistically improve cardiac function of the infarcted rats; The research of surgical approach of right ventricular outflow tract construction for pulmonary atresia with ventricular septal defect in infant and young children;Double switch operation for congenital corrected transposition of great arteries with heart anomaly; Surgical treatment of cardiac valve disease in the elderly; Comparison of decellularizative procedures of bovine pericardium tissueengineering heart valve scaffold;……     

Heart, cardiovascula, vascular disorder

C-myc antisense oligodeoxynucleotides transferred by soluble stent preventing vein graft stenosis, Surgical indication for treatment of congenital heart disease with severe pulmonary hypertension,Inhibition effects of complement depletion with CVF on cardiac allografts rejection in inbred strain rats,Bentall procedure with composite tissue valve conduit, Long-term follow-up of tricuspid valve function by color Doppler echocardiography after mitral valve replacement[第一段]     

Heart,cardiovascula,vascular disorder

<正>209409 Mechanical ventilation affects inflammatory mediators in patients undergoing coronary artery bypass grafting/Yan Hengyu(闫恒宇,Dept Cardiaovasc Surg,Gen Hosp Anshan Iron Steal Company,Anshan 114010)…∥Chin J Thorac Cardiovasc Surg.-2009,25(2).-118～120Objective Not only the systemic inflammation and acute organ injury are all caused by inflammatory mediators but also the intension of them are closely related to the levels of inflammatory mediators.Through observation on the content of Interleukin 6,Interleukin 8 in two different mechanical ventilation groups(high tidal volumes/low positive end-expiratory pressure,low tidal volumes/high positive end-expiratory pressure)to find which is the better ventilatory method to the patients undergoing coronary artery bypass grafting.Methods Forty patients undergoing elective coronary artery bypass were randomized to be ventilated after cardiaopulmonary bypass disconnection with high tidal volumes/low positive end-expiratory pressure(10-12 ml/kg and 2-4 cm H2O)or low tidal volumes/high positive end-expiratory pressure(6-8 ml/kg and 8-10 cm H2O).Interleukin 6 and Interleukin 8 levels were measured in the bronchoalveolar lavage fluid and plasma.Samples were taken before sternotomy(T0),immeditately after cardiaopulmonary bypass separation(T1),and after 6 hours of mechanical ventilation(T2).Results Interleukin 6 and Interleukin 8 levels in the bronchoalveolar lavage fluid and plasma significantly increased at T1 in both groups but further increased sighificantly at T2 only in patients ventilated with high tidal volumes/low positive end-expiratory pressure.Conclusion Ventilation with low tital volumes/high positive end-expiratory pressure does not increased the level of inflammatory mediators,protects the systemic function to patients,avoids acute organ injury,is the better ventilatory method for patients undergoing coronary artery bypass grafting from cardiaopulmonary bypass.6 refs,3 tabs.     

Heart, cardiovalvula, vascular disorder

Diagnosis of interventricular septmn dissection aneurysm with echocardiogram, Midterm follow-up of surgical treatment for is - chemic mitral regurgitation , A preliminary research to evaluate the effects of Dor procedure on left ventricular three-dimensional shape and funetion , An early stage morphologic analysis for nonre. strictive external stent to prevent vein graft failure,Study of EPO pretreatment＇s effect on expression of TNF-α gene in cultured cardiac myocytes with hypoxia/reoxygenation injury and the possible mechanism     

Heart, cardiovascnla, vascular disorder

The clinical study of circmnferentlal ablation around orifice of pulmonary vein by radiofrequeacy energy with chronic atrial fibrillation undergoing rheumatic valvular heart surgery,Coronary endarterectomy and bypass grafting without cardiopulmonary bypass for patients with dlf. fused coronary artery disease,Intracoronary transfection of transforming growth factor β1 gene attenuates acute rejection of cardiae allograft in rats     

Heart, cardiovalvula, vascular disorder

Pathological changes of radial artery used for coronary artery bypass grafting and its related risk factors for intimal hyperplasia; Clinical experience of simultaneous aortic operation and coronary artery bypass grafting; Pulsatile-flow-cultivation recellularization of homograft bioprosthetic valve;Assessment of antegrade/retrograde cardioplegia by magnetic resonance technique; Ventricular performance changes of functional single ventricle in various stages of operation assessed by magnetic resonance imaging;……     

Heart, cardiovalvula, vascular disorder

Experimental study on mechanical properties of decellularized porcine aortic valve and effects of precoating methods of biological scaffold on histocmpatibility; New preparation of acellular aortic valve conduit scaffold by using sodium n-lauroyl sarcosine and function analysis; Effects of ischemic postconditioning on myocardial cell during ischemia/reperfusion period in rabbits     

Heart cardiovalvula vascular disorder

<正>209555 Extracorporeal membrane oxyenation support in acute cardiorespiratory function failure patients after cardiac surgery/Jia Ming(贾明,Dept Post-opera ICU Cardiac Surg,Cap Univ Med Sci Affil Beijing Anzhen Hosp,Beijing 100029)…∥Chin J Surg. -2009,47(18). -1397 ～1399     

Cerebral vascular disorder

<正>209527 Transvenous embolization of cavernous sinus dural arteriovenous fistulaes/Liu Lian(刘恋, Beijing Neurosurg Inst,Cap Univ Med Sci,Beijing 100050)…∥Chin J Neurosurg. -2009,25(8). -695 ～698     

急性脑血管病与代谢紊乱的关系

目的　探讨急性脑血管病与代谢紊乱的关系。方法　对 2 72名上海地区正常人及 92 3例急性脑血管病 (5 0 3例脑梗死、4 2 0例脑出血 )患者住院的基线资料进行分析。结果　① 5 0 3例脑梗死、4 2 0例脑出血患者的年龄、体重指数 (BMI)、血压、血糖、低密度脂蛋白 (LDL)值均高于对照组 (P <0 .0 5 )。②脑梗死、脑出血患者中 ,伴高血压者分别为 95 .0 %、97.1% ;伴高血糖者分别为 4 4 .0 %、39.7% ;伴高三酰甘油 (TG) /低高密度脂蛋白 (HDL)分别为 34.8%、38.1% ;③脑梗死、脑出血患者中 ,合并代谢综合征者分别占 14 .7%、16 .7% ;合并 2种代谢紊乱者分别占 4 6 .9%、4 3.1% ;合并 1种代谢紊乱者分别占 36 .0 %、38.8% ;无代谢紊乱者仅分别占2 .4 %、1.4 %。④脑梗死、脑出血患者中 ,除代谢紊乱者血压均显著高于对照组及无代谢紊乱者外 ,合并 2种以上代谢紊乱患者中BMI、血糖、TG均高于对照组及无代谢紊乱者 (P <0 .0 5 )。结论　急性脑血管病患者多伴有多种代谢紊乱 ,因而 ,有效控制代谢紊乱与预防脑血管病的发生、发展及其预后有关     

氨溴索、酚妥拉明、多巴酚丁胺治疗肺心病顽固性心衰疗效观察

目的:探讨氨溴索,酚妥拉明,多巴酚丁胺联合治疗肺心病顽固性心衰的临床疗效。方法:选择综合治疗加合理应用强心剂利尿剂为对照组与综合治疗加用氨溴索,酚妥拉明,多巴酚丁胺为治疗组的对比治疗。结果:治疗组对缓解临床症状,改善肺心功能明显优于对照组。结论:此方案对治疗肺心病顽固性心衰是一种较为有效的方案,较好地改善患者的生活质量,降低死亡率。     

代谢紊乱患者脂联素水平和血管内皮细胞功能的变化

目的探讨代谢紊乱患者脂联素水平和内皮依赖性血管舒张功能(EDF)的关系。方法100例患者根据代谢紊乱的数目,分为无代谢紊乱组(对照组,M0)、1项代谢紊乱组(M1)、2项代谢紊乱组(M2)和代谢综合征组(M3)。采用高分辨率血管外彩色超声测定肱动脉内径,以肱动脉反应性充血前后血管内径变化百分比反映EDF,并测定脂联素、一氧化氮(NO)、一氧化氮合成酶(NOS)、内皮素-1(ET-1)的水平。结果随着代谢紊乱数目的增多,BMI、SBP、TG、FINS、HOMA-IR呈增高趋势,HDL-C呈降低趋势,各组间比较差异有显著意义(P<0.05或P<0.01)。M2组和M3组EDF、NO、NOS下降,ET-1升高,与M0组比较差异有显著意义(P<0.05或P<0.01);M3组ET-1与M2组比较差异有显著意义(P<0.05);M3组NO、NOS、ET-1与M1组比较差异有显著意义(P<0.05);M3组脂联素水平与HOMA-IR呈负相关(r=-0.516,P<0.05)。结论脂联素可能通过影响内皮细胞NOS活性、NO和ET-1的分泌,维持正常内皮细胞的功能。     

川芎嗪拮抗激素所致兔血管内皮细胞功能失调

目的：探讨川芎嗪拮抗糖皮质激素引起的血管内皮细胞功能失调。方法：健康雄性家兔40只，随机分为A组（注射生理盐水），B组（短期注射地塞米松）及C组（短期注射地塞米松＋川芎嗪）。在实验前及实验15，30，60d，观察3组家兔血小板数量、血浆血栓素、前列环素、组织纤溶酶原激活物及纤溶酶原激活物抑制物的变化。结果：实验前3组的各项检测指标均无显著差异。用药后，3组的血小板数量未发生有意义的变化。B组tPA/PAI比值显著降低。TXB2／PGI2含量比值长期升高。C组tPA/PAI比值各阶段均显著高于B组，而TXB2／PGI2比值各阶段均显著低于A、B组。结论：川芎嗪能够有效拮抗大剂量地塞米松造成的兔血管内皮细胞功能失调，可能对某些糖皮质激素并发症的临床防治有一定效果。