20例女性乳腺结核患者的CT特征分析

目的 分析女性乳腺结核的CT征象,探讨CT扫描对此类患者的诊断价值。方法 收集重庆市公共卫生医疗救治中心2015年8月至2019年5月行胸部CT检查时发现乳腺病变并经手术病理证实的20例女性乳腺结核患者,分析其CT表现及邻近组织及器官受累情况。结果 20例乳腺结核中12例发生于右乳,8例发生于左乳;13例为单发,7例为多发;16例呈结节状,1例呈团块状,3例呈片状;病灶大小1.0cm×1.5cm~5.1cm×3.2cm。CT平扫显示,11例病灶呈等密度,9例呈稍低密度,4例病灶内见结节状钙化,17例显示边界模糊;12例邻近皮肤呈均匀性增厚。CT增强扫描显示,15例病灶表现为环形强化,3例表现为不均匀强化,2例表现为均匀强化,2例伴窦道形成;其中13例并发同侧或双侧腋窝淋巴结结核,伴环形强化;5例并发同侧胸壁结核,伴边缘强化;10例并发肺结核。结论 乳腺结核的特征性CT表现为环形强化,同时常并发同侧腋窝淋巴结结核、胸壁结核及肺结核。     

肾上腺肿瘤的CT表现及其鉴别

目的 分析肾上腺肿瘤的CT表现及特征,以提高诊断水平.方法 回顾性分析经手术病理证实和随访证实的各类肾上腺肿瘤53例,分析其CT征象.结果 53例中,皮质腺瘤23例,多数较小,密度低而均匀,强化轻;嗜铬细胞瘤8例,肿块较大,密度不均匀,强化明显;皮质腺癌5例,为＞7.3 cm的肿物,密度不均匀;转移瘤12例,表现多样,肿块大小不等,密度不均匀;髓质脂肪瘤4例,低密度的脂肪密度区是其特征性CT表现;平滑肌瘤1例,定性诊断较难.结论 综合分析肾上腺肿瘤的各种CT征象,结合临床表现及生化检查多数能作出正确的诊断.     

肺结核患者的不典型CT表现

目的 探讨和分析肺结核患者的不典型CT表现特点。 方法 回顾性分析我院2010年1月至2012年9月CT表现不典型的肺结核患者73例,根据其图像特点进行分类并分析。 结果 所有患者按图像特点分为6型,其中多空洞型7例,表现为肺内多发空洞,无结核播散灶;肺间质型20例,表现为肺内大片细网织样密度增高影,与周围正常肺组织分界清晰,病变区内部分病灶融合实变,并可见多发垂直于胸膜的小叶间隔增厚影;雪花型16例,4例合并间质型,表现为多发腺泡样结节沿小支气管及其分支周围分布,受累各级支气管管腔充盈,内形成多发“小树芽征”及小叶性实变;肿块型29例,病灶边缘可见光滑、深分叶、长毛刺及胸膜凹陷征,未见短毛刺征,病灶平扫为等密度,其中3例肿块呈薄壁或厚环形强化,7例有不同程度的强化;肺门及纵隔淋巴结结核并假性动脉瘤型1例,表现为环形强化的淋巴结内出现假性动脉瘤;实变型4例,为多发段、叶实变,段、叶支气管腔内无异常改变。 结论6种肺结核的不典型CT表现中,肺间质型、雪花型和肺门及纵隔淋巴结结核并假性动脉瘤型有一定特异性,但所有类型需结合临床、化验检查等做出诊断。     

肾上腺结核CT诊断

目的分析肾上腺结核的CT表现并探讨其影像学特征。方法分析21例肾上腺结核的CT检查,其中男16例,女5例,年龄20~80岁。均行CT扫描。所有病例均经临床诊断。结果肾上腺结核依病期不同而有2种不同的影像学表现:双肾上腺增大,内含低密度区,增强扫描呈环形或分隔状强化;双肾上腺腺体萎缩及钙化。结论当全身多脏器结核同时伴有肾上腺的影像变化时,应考虑肾上腺结核的诊断。     

37例卵巢及输卵管结核的CT特征分析

目的探讨卵巢及输卵管结核的CT表现及诊断价值。方法收集滨州市结核病防治院2009年5月至2016年3月收治的37例卵巢及输卵管结核患者,其中11例通过腹腔镜手术一病理检查确诊,其余26例经临床病史、影像学及实验室检查、治疗随访确诊。37例患者均进行了CT平扫和增强扫描。对患者子宫附件区病变的形态、密度、与周围结构的关系及强化特点等进行观察。结果37例患者CT平扫表现为子宫附件区囊性（3例）、囊实性（20例）、实性（14例）肿块;27例患者病变与子宫及周围结构粘连;37例患者伴盆腔或腹盆腔积液23例,其中少量积液19例（呈包裹性积液15例）,中等量积液3例（呈包裹性积液2例）,大量积液1例;附件区钙化灶4例。37例患者CT增强扫描显示子宫附件区囊性肿块边缘强化23例,囊壁均匀;实性部分轻度强化3例,环状强化及蜂窝状强化31例,其余3例为囊性肿块;腹膜均匀增厚20例,网膜污迹样增厚4例,呈饼状网膜1例,肠系膜污迹样增厚12例;腹、盆腔淋巴结环状强化5例。结论CT检查对卵巢及输卵管结核有重要的诊断价值,子宫附件区对称性软组织块呈多发环状、蜂窝状强化可能是相对特异的CT特征。     

胸壁结核的CT诊断

目的探讨胸壁结核的CT表现及诊断。方法收集滨州市结核病防治院2002年11月—2009年3月期间的87例胸壁结核,全部病例经CT检查并手术病理确诊,15例做了增强扫描。结果(1)CT平扫表现为胸壁半圆形或扁平状软组织肿块影,边缘密度较高,中央密度较低,"哑铃状"中央低密度肿块较具有特征性CT表现。骨和关节破坏15例,肋骨局部皮质缺损样破坏9例,膨胀性溶骨性破坏3例;(2)增强扫描14例边缘强化,1例肿块内见多发低密度区,较平扫时显示更清晰。结论CT对胸壁结核的诊断及鉴别诊断有重要价值。     

肾上腺结核CT诊断

目的 分析肾上腺结核的CT表现并探讨其影像学特征。方法分析21例肾上腺结核的CT检查所见，其中男16例，女5例，年龄20～80岁。均行CT扫描。所有病例均经临床诊断。结果肾上腺结核依病期不同而有两种不同的影像学表现：双肾上腺增大，内含低密度区，增强扫描呈环形或分隔状强化；双肾上腺腺体萎缩及钙化。结论当全身多脏器结核，同时伴有肾上腺上述影像变化，应考虑肾上腺结核的诊断。     

多层螺旋CT检查在睾丸原发肿瘤诊断中的应用

目的观察睾丸原发肿瘤的多层螺旋CT表现,探讨多层螺旋CT检查对睾丸原发肿瘤的诊断价值。方法回顾性分析25例经手术病理证实的睾丸肿瘤患者的多层螺旋CT特点。结果 25例CT图像均表现为单侧睾丸不同程度的增大,边界清楚。呈密度均匀或不均匀软组织密度肿块的13例为精原细胞瘤,其中囊变坏死6例,增强扫描为不均匀轻度强化,有分隔样强化4例。畸胎瘤4例,其中良性畸胎瘤3例,呈点状或弧形钙化,成熟型畸胎瘤1例见脂肪成分,2例良性畸胎瘤增强后囊壁、分隔及实性成分呈轻度强化;恶性畸胎瘤1例,呈不均匀等低密度类圆形肿块,内见囊变坏死。混合性生殖细胞瘤3例、胚胎癌2例、内胚窦瘤1例,均呈囊实性肿块,增强后不均匀,较明显强化。间质细胞瘤1例,CT显示睾丸内略高密度结节,内有点状钙化,增强扫描结节呈明显强化。含有生殖细胞和性索/性间质成分混合性肿瘤1例,平扫为均匀等密度类圆形肿块。结论睾丸肿瘤的多层螺旋CT表现有一定特征性,亦存在相似和重叠现象,结合患者年龄、临床资料及血清学检查可提高术前诊断的准确性。     

16例肾上腺结核的临床分析

目的:探讨肾上腺结核患者的临床特征,以期提高临床医师对肾上腺结核的认知。方法:收集我院自2003年1月1日至2013年12月31日临床诊断为肾上腺结核的16例患者,对其临床表现、影像学检查及治疗进行分析。结果:15例(88%)患者有肾上腺皮质功能减退症状,如皮肤黏膜颜色加深伴色素沉着(14例),纳差、消瘦(12例),乏力、易疲劳(12例),性欲减退及性功能下降(3例)等。肾上腺结核CT表现为肾上腺增粗(14例)或缩小(1例)、病灶内出现斑片样钙化影(7例),病灶可强化(11例)。诊断后行抗结核及激素治疗等对症治疗,临床症状得到改善,但促肾上腺皮质激素(ACTH)[(1 286.0±947.7)ng/L]、血氢化可的松[(70.27±26.40)μg/L]及24 h尿氢化可的松[(311.88±243.13)μg/24 h]未得以恢复。1例患者表现为肾上腺脓肿,经手术治疗后痊愈。结论:肾上腺结核可引起肾上腺分泌功能紊乱,可根据CT表现进行初步诊断,规律抗结核辅以激素治疗等对症治疗可以改善临床症状,不能改善肾上腺功能。     

33例肺结核不典型CT征象分析

目的 分析肺结核的不典型CT影像特点,提高诊断正确率。 方法 回顾性分析33例肺结核不典型CT影像特点,并与50例周围型肺癌、33例浸润性肺癌、62例肺部非特异性炎症（球形肺炎33例,表现为片状影的炎症29例）的CT征象进行比较分析。肺结核及对照病例按照病变形态分为两个小组并分别进行比较分析,计数资料采用χ^2验,P〈0.01为差异有统计学意义。 结果 33例影像表现不典型的肺结核患者中,第1小组15例结核球中9例（60.0%）CT平扫显示病变实质出现1个或多个小片状低密度区,境界模糊;CT增强扫描结核球以不均匀强化为主,占66.7%（10/15）,实质内有多个小点片状且境界模糊的低密度灶。球形肺炎及周围型肺癌以均匀强化为主,占75.8%（25/33）和66.0%（33/50）,增强后CT值测量结果,10例结核球增强后CT值增加值范围在16～20 HU之间,31例球形肺炎及42例周围型肺癌增强后CT值增加值＞21 HU,结核球与球形肺炎、周围型肺癌CT值增加值比较差异具有统计学意义（χ^220.202、20.872,P值均〈0.01）。第2小组CT表现形态均一的继发性肺结核18例CT平扫仅2例（11.1%,2/18）病灶实质显示多少不等略低密度区、境界模糊,与肺炎（2/29）及肺癌（0/33）之间比较差异无统计学意义。增强扫描12例肺结核患者中10例（83.3%）病灶显示不均匀强化,病灶实质表现为多少不等的小片状无强化区,且境界模糊;肺炎患者仅2例（10.5%,2/19）出现小片状坏死液化区,且境界清楚,肺癌患者增强后均未出现坏死区,肺结核组与对照组间比较差异有统计学意义（χ^216.433、27.692, P值均〈0.01）。 结论 肺结核不典型CT表现多种多样,片状及球形病灶密度不均匀及轻度强化对诊断具有一定价值,对难以鉴别的患者应密切结合临床表现及穿刺活检进行诊断。     

Adrenal tuberculosis in Cushing's disease with bilateral macronodular adrenocortical hyperplasia

Cushing's disease is a disorder of hypercortisolism caused by a pituitary micro- or macro-adenoma. Most patients with Cushing's disease have a bilateral adrenal enlargement, which depends on the duration of the disease, as a result of the long standing ACTH stimulation of both adrenal glands. However, in macronodular adrenocortical hyperplasia (MNH) that is caused by Cushing's disease, if the MNH gains autonomy, a bilateral adrenalectomy, as well as the removal of pituitary adenoma, is often essential. We encountered a patient diagnosed with Cushing's disease with bilateral adrenal tuberculosis simulating MNH. She had taken anti-tuberculosis medications one year prior to admission due to spinal tuberculosis. Sellar MRI revealed a pituitary macroadenoma, but adrenal CT showed enlargement in both adrenal glands that appeared to be MNH. A hormonal study and bilateral inferior petrosal sinus sampling revealed Cushing's disease. Therefore, she underwent trans-sphenoidal surgery of the pituitary mass. The pituitary surgery was successful and the serum cortisol returned to normal range. However, the adrenal mass rapidly enlarged after removing the pituitary tumor without showing evidence of a recurrence or adrenal autonomy of hypercortisolism. Accordingly, a laparoscopic left adrenalectomy was performed to examine the nature of the mass. The resected left adrenal gland was pathologically determined to have a lesion of tuberculosis with some part of the intact cortex. So we assumed that the cause of rapid adrenal enlargement might be due to adrenal tuberculosis. In summary, to the best of our knowledge, this is the first case of Cushing's disease coexisting with both adrenal tuberculosis simulating a bilateral MNH.     

56例结核性腹膜炎患者CT影像分析

目的 探讨结核性腹膜炎（TBP）特征性CT影像表现及治疗中影像动态变化的特点。方法 回顾性分析56例临床及病理确诊的TBP患者,观察分析CT影像特征,包括腹腔积液、腹膜（壁腹膜、肝包膜、大网膜及肠系膜）及腹腔淋巴结。56例均行CT平扫+增强扫描。治疗过程中收集动态复查CT影像。结果 腹腔积液45例,大量1例,中少量44例,限制性38例,CT值>20 HU者34例。壁腹膜增厚46例,肝脏边缘部腹膜均有受累,均匀增厚17例,扁丘状凸起或腹膜结核瘤29例,增强扫描结核瘤边缘强化,肝包膜或肝脏受累15例;网膜增厚35例,结节及斑片34例,网膜饼1例,增强扫描网膜饼呈轻度不均匀强化;肠系膜增厚41例,表现为斑片、结节及线状、星芒状条索状高密度影,与肠袢粘连,增强扫描肠系膜血管包埋其内,走形扭曲。腹腔及腹膜后淋巴结增大19例,伴钙化5例,簇集状排列,增强扫描环状或蜂窝状强化。17例完整的动态CT图像,腹腔积液吸收最快,网膜及肠系膜病变吸收稍慢,腹膜结核瘤缩小速度最慢。结论 TBP的CT诊断为多种征象的综合,中少量腹腔积液伴壁腹膜、网膜及肠系膜的增厚粘连是最为常见的影像表现;CT影像动态变化对临床评价疗效具有重要意义。     

Primary adrenal lymphoma presenting as Addison's disease. Case report and review of the literature

Primary Adrenal Lymphoma (PAL) is a very rare clinical entity. Adrenal insufficiency is a common complication of this pathology. Most patients present with clinical and laboratory findings of adrenal insufficiency and bilateral enlargement of the adrenal glands. We present a 78-year-old woman admitted to our institution with typical clinical and laboratory findings of adrenal insufficiency. Computerized tomography (CT) of the abdomen revealed bilateral enlargement of the adrenal glands. The patient was eventually diagnosed with a diffuse large B-cell lymphoma after a CT-guided needle adrenal biopsy and treated with combined immuno-chemotherapy (R-LPD-COP). Twenty months after the initial evaluation, she is in good condition, with no signs of adrenal insufficiency.     

A case of adrenal tuberculosis complicated with acute exacerbation of adrenal insufficiency during the initial phase of anti-tuberculosis therapy for pulmonary tuberculosis

A 36-year-old male was admitted to our hospital because of adrenal insufficiency. About one month before admission, he was diagnosed as pulmonary tuberculosis and started anti-tuberculosis therapy with isoniazid, rifampicin, ethambutol, and pyrazinamide. On the tenth day, general fatigue, abdominal pain, nausea and diarrhea developed, and laboratory examination showed hyponatremia [126 mEq/l]. Enhanced CT on admission revealed bilateral adrenal mass-like enlargement, and further examination showed high level of plasma ACTH, and low level of cortisol. These findings led to a diagnosis of adrenal insufficiency caused by adrenal tuberculosis. He was treated with hydrocortisone and his signs and symptoms rapidly improved. We suppose adrenal insufficiency became clinically apparent because rifampicin reduced half-life of serum cortisol. Interestingly we observed rapid increase and decrease in size of bilateral adrenal glands on CT scan during the course.     

胰腺结核九例的MDCT特征和误诊分析

目的 分析胰腺结核(pancreatic tuberculoses,PT)的多层螺旋CT(MDCT)征象,以期提高对该病的认识和诊断正确率.方法 收集2003年至2009年行MDCT检查并最终确诊为PT的9例患者,其中2例行MDCT血管成像.分析PT的MDCT特征性表现,并与手术及病理结果进行比较.结果 MDCT诊断为胰腺癌1例、囊腺癌1例、囊腺瘤2例、假性囊肿1例、胰腺癌伴后腹膜淋巴结转移2例、淋巴瘤2例.通过病理证实,9例均为PT,误诊率达100%.PT常表现为胰头肿块,亦可累及体尾部或整个胰腺.MDCT呈现等或略低密度的囊实性肿块,偶见钙化,增强后轻度至中度环形强化.通常不伴有胰管扩张,但常伴有后腹膜或邻近淋巴结肿大,且肿大淋巴结亦呈环形强化.有时伴有腹部其他脏器结核.结论 环形强化的肿块不伴有胰管扩张,同时伴有环形强化的肿大淋巴结为PT特征性的MDCT表现.     

肾上腺结核CT诊断

目的　分析肾上腺结核的CT表现并探讨其影像学特征。方法 分析21例肾上腺结核的CT检查,其中男16例,女5例,年龄20～80岁。均行CT扫描。所有病例均经临床诊断。结果 肾上腺结核依病期不同而有2种不同的影像学表现:双肾上腺增大,内含低密度区,增强扫描呈环形或分隔状强化;双肾上腺腺体萎缩及钙化。结论 当全身多脏器结核同时伴有肾上腺的影像变化时,应考虑肾上腺结核的诊断。     

Imaging diagnosis of 12 patients with hepatic tuberculosis

AIM: To assess CT, MR manifestations and their diagnostic value in hepatic tuberculosis. METHODS: CT findings in 12 cases and MR findings in 4 cases of hepatic tuberculosis proved by surgery or biopsywere retrospectively analyzed. RESULTS: (1) CT findings: One case of serohepatic type of hepatic tuberculosis had multiple-nodular lesions in the subcapsule of liver. Parenchymal type was found in 10 cases, including multiple, miliary, micronodular and low-density lesions with miliary calcifications in 2 cases; singular, low-density mass with multiple flecked calcifications in 3 cases; multiple cystic lesions in i case; multiple micronodular and low-density lesions fusing into multiloculated cystic mass or “cluser“ sign in 3 cases; and singular, macronodular and low-density lesion with multiple miliary calcifications in 1 case. One case of tuberculous cholangitis showed marked dilated intrahepatic ducts with multiple flecked calcifications in the porta hepatis. (2) MR findings in 4 cases were hypointense on both Tl-weighted imagings and T2-weighted imagings in one case, hypointense on Tl-weighted imagings and hyperintense on T2-weighted imagings in 3 cases. Enhanced MR in 3 cases was slightly shown peripheral enhancementor with multilocular enhancement. CONCLUSION: Various types of hepatic tuberculosis have different imaging findings, and typical CT and MR findingscan suggest the diagnosis.     

A critical examination of adrenal tuberculosis and a 28-year autopsy experience of active tuberculosis

OBJECTIVE: Tuberculosis is potentially fatal and adrenal gland involvement is uncommonly reported. The aims of the current study were to define the characteristics of tuberculosis in hospitalized patients and to analyse the features of adrenal tuberculosis. DESIGN: Retrospective analysis of autopsies and adrenalectomies. PATIENTS: 13,762 patients (13492 at autopsies and 270 at adrenalectomy). MEASUREMENTS: The presence of active tuberculosis, the predisposing factors, the pathological features and organs of involvement were examined. RESULTS: Active tuberculosis was present in 871 patients (6.5% of all 13492 autopsies). It was first diagnosed in 70% of these patients during autopsy. Cancers and a history of recent major operations were the 2 main concomitant factors in the patients with tuberculosis. Extra-pulmonary tuberculosis was seen in 261 patients (30%). The five most common extra-pulmonary sites of tuberculosis were the liver, spleen, kidney, bone and adrenal gland. Adrenal tuberculosis was seen in 52 of the 871 patients (6%) with active tuberculosis at autopsy and in 3 patients at adrenalectomy. The adrenal gland was the only organ involved by active tuberculosis in 14 of these 55 patients (25%; 35 men, 20 women). Tuberculosis was evident on macroscopic examination of the adrenal glands in 46% of the patients. On histological examination, caseous necrosis and granulomatous inflammation with Langhan's giant cells were seen in 71% and 40% of patients, respectively. Seven patients presented with signs and symptoms of Addison's disease due to bilateral adrenal involvement. Langhan's giant cells were frequently seen in histological sections and bilateral enlargement of the adrenal glands was often noted. Fine needle aspiration cytology was not useful for diagnosing adrenal tuberculosis. CONCLUSION: Unexpected and extra-pulmonary tuberculosis such as adrenal tuberculosis has been a common problem. A high index of suspicion, correct diagnosis and proper treatment are essential for the management of tuberculosis.     

12例ACTH非依赖性肾上腺皮质大结节样增生的诊治

目的 探讨ACTH非依赖性肾上腺皮质大结节样增生(AIMAH)的诊断与治疗.方法 回顾性分析12例AIMAH患者的临床表现、内分泌检查、影像与病理特点以及治疗和预后.男性5例,女性7例,平均年龄48岁(29～66岁).结果 7例有典型库欣综合征表现,5例则仅有高血压或高血糖等非特异性症状.内分泌检查显示皮质醇分泌失去昼夜节律,大、小剂量地塞米松抑制试验均不被抑制.CT或MRI示双肾上腺弥漫性增大伴多发结节.11例行手术治疗,其中双侧肾上腺切除3例;一侧肾上腺全切,对侧肾上腺次全切除1例;单侧肾上腺切除7例.病理诊断肾上腺结节样或腺瘤样增生.随访14～124个月,库欣综合征症状消失.双侧肾上腺切除者无Nelson综合征出现,单侧肾上腺切除者血尿皮质醇在正常范围,对侧肾上腺无明显增大.结论 AIMAH有独特的临床病理特点,单侧肾上腺切除是一种安全、有效的治疗选择.对症状不缓解或复发者可行双侧肾上腺切除或一侧肾上腺全切、对侧肾上腺次全切除.

Abstract：

Objective To explore the diagnosis and treatment of adrenocorticotropin-independent macronodular adrenal hyperplasia (AIMAH). Methods The clinical symptoms, endocrinological and radiological characteristics, treatment modalities, and postoperative clinical course of 12 AIMAH patients were retrospectively reviewed. There were 5 men and 7 women with an average age of 48 years old. Results All cases had some clinical features and biochemical evidence of Cushing's syndrome. The circadian rhythm of serum cortisol was abnormal. Low- and high-dose dexamethasone suppression tests failed to suppress cortisol secretion. CT or MRI scan showed bilateral enlargement of the adrenal glands with multiple macronodules. Bilateral adrenalectomy was performed in three patients and unilateral adrenalectomy combined with contralateral subtotal adrenalectomy was performed in one patient. Seven patients underwent unilateral adrenalectomy of the larger gland. The removed adrenal glands weighted within 8-96 g range and pathologic diagnoses were nodular or adenomatoid hyperplasia of adrenal cortex. The duration of postoperative follow-up was 14 to 124 months. Clinical symptoms of Cushing's syndrome disappeared after surgery in all cases and there was no Nelson's syndrome after bilateral adrenalectomy. Urinary free cortisol and serum cortisol were within normal ranges. No further enlargement of the contralateral gland has been noticed in patients who received unilateral adrenalectomy during the follow-up.Conclusions AIMAH had unique endocrinological and pathological features. Unilateral adrenalectomy appears to be an effective and safe alternative treatment for AIMAH. Bilateral adrenalectomy or unilateral adrenalectomy combined with contralateral subtotal adrenalectomy may be performed if the symptoms had not been improved or recurred after unilateral adrenalectomy.     

Image diagnosis of adrenal disorders--II. Cushing's syndrome

Comparative study of image diagnosis of ultrasonography (US) by linear electronic scanner, computed tomography (CT), and adrenal scintigraphy was performed in 14 patients with Cushing's syndrome. Adrenal imaging by scintigraphy was performed at the 5th and 6th day or further 7th day following the injection of 1 mCi of Adosterol. Cushing's disease (11 cases) US failed to detect the adrenals in 4 cases examined. Measurement of the adrenals on CT film demonstrated the enlargement of adrenals (greater than mean + 2SD) in 6 of 7 cases (85.7%). Scintiscanning showed the increased uptake of bilateral adrenals in 4 of 10 cases (40%). Adrenal scintigraphy with dexamethasone pretreatment (DP) still demonstrated the isotope uptake of bilateral adrenals in all of those 4 cases tested, although the other 6 cases were not studied with DP. From these findings, it was suggested that the measurement of adrenal size by CT was useful for the additional image diagnosis of Cushing's disease, and the adrenal scintigraphy with DP was also available for complementary study of Cushing's disease. Cushing's syndrome due to adrenocortical adenoma (3 cases) In one case examined by US, which had the smallest adenoma (0.6 X 1.0 X 2.0 cm) in this syndrome, the adenoma was not detected. All of 3 adrenal adenomas (2.6 X 2.6 X 2.2 cm to 0.6 X 1.0 X 2.0 cm) were detected by CT. Adrenal scintigraphy demonstrated good uptake by adrenal adenoma but no visualization of the contralateral adrenal in every case.