Sex Chromosomal Analysis of Fifty Cases with Azoospermia

ＳｅｘＣｈｒｏｍｏｓｏｍａｌＡｎａｌｙｓｉｓｏｆＦｉｆｔｙＣａｓｅｓｗｉｔｈＡｚｏｏｓｐｅｒｍｉａ￥ＸｕＣｈａｎｇｆｅｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：２２－２５Ａｂｓｔｒａｃｔ：Ｍａｌｅ...     

A Study on Early Biological Effects of Oral Administration of Terephthalic Acid in Rats

ＡＳｔｕｄｙｏｎＥａｒｌｙＢｉｏｌｏｇｉｃａｌＥｆｆｅｃｔｓｏｆＯｒａｌＡｄｍｉｎｉｓｔｒａｔｉｏｎｏｆＴｅｒｅｐｈｔｈａｌｉｃＡｃｉｄｉｎＲａｔｓ￥ＱｉｕＱｉｎｇ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＦ，ＮＡＮＪＩＮＧ，１９９４，１...     

Effects of Rapeseed Oil Fume on Phagocytosis of Leucocytes in Mice

ＥｆｆｅｃｔｓｏｆＲａｐｅｓｅｅｄＯｉｌＦｕｍｅｏｎＰｈａｇｏｃｙｔｏｓｉｓｏｆＬｅｕｃｏｃｙｔｅｓｉｎＭｉｃｅ￥ＣｈｅｎＹｏｎｇｊｕａｎ；ＣｈｅｎＹｕｌｉａｎ；ＷｅｎｇＮｉａｎｎｏｎｇ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ．１...     

Clinical Analysis of Cytomegalovirus Infecion in 54 Adults

ＣｌｉｎｉｃａｌＡｎａｌｙｓｉｓｏｆＣｙｔｏｍｅｇａｌｏｖｉｒｕｓＩｎｆｅｃｉｏｎｉｎ５４ＡｄｕｌｔｓＴａｎｇＱｉｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：５０－５２Ａｂｓｔｒａｃｔ：Ｆｉｆｔｙ－...     

Amino Acid Analysis of Astragalus Membranaceus (Fisch.)Bge

ＡｍｉｎｏＡｃｉｄＡｎａｌｙｓｉｓｏｆＡｓｔｒａｇａｌｕｓＭｅｍｂｒａｎａｃｅｕｓ（Ｆｉｓｃｈ．）Ｂｇｅ￥ＺｈａｏＦｕｚｈｏｎｇ；ＺｈｕａｎｇＢｉｎｉａｎ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ．１９９５，１５（２）：２７０（Ｄｅ...     

A Brief Note on Pathogenesis and Treatment of Perthes Disease

ＡＢｒｉｅｆＮｏｔｅｏｎＰａｔｈｏｇｅｎｅｓｉｓａｎｄＴｒｅａｔｍｅｎｔｏｆＰｅｒｔｈｅｓＤｉｓｅａｓｅ￥ＦａｎＷｅｉｍｉｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：４４－４６Ａｂｓｔｒａｃｔ：Ｍｅ...     

Dynamic Analysis of Morbidity and Mortality of Cardiovascular Diseass in Countryside

ＤｙｎａｍｉｃＡｎａｌｙｓｉｓｏｆＭｏｒｂｉｄｉｔｙａｎｄＭｏｒｔａｌｉｔｙｏｆ　ＣａｒｄｉｏｖａｓｃｕｌａｒＤｉｓｅａｓｓｉｎＣｏｕｎｔｒｙｓｉｄｅＹａｏＣａｉｌｉａｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４...     

A Study on Morphologic Feature of Dentinal Hypersensitivity by SEM

ＡＳｔｕｄｙｏｎＭｏｒｐｈｏｌｏｇｉｃＦｅａｔｕｒｅｏｆＤｅｎｔｉｎａｌＨｙｐｅｒｓｅｎｓｉｔｉｖｉｔｙｂｙＳＥＭ￥ＳｕｎＷｅｉｂｉｎ，ｅｔａｌ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ，１９９４，１４（１）：１６－１８Ａｂｓｔｒａ...     

Protective Effects of Berberine on Cerebral Ischemia in Mice and Rats

ＰｒｏｔｅｃｔｉｖｅＥｆｆｅｃｔｓｏｆＢｅｒｂｅｒｉｎｅｏｎＣｅｒｅｂｒａｌＩｓｃｈｅｍｉａｉｎＭｉｃｅａｎｄＲａｔｓ￥ＳｉＹｉｊｕ；ＷｕＪｕｎｆａｎｇ；ＬｉｕＴｉａｎｐｅｉ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ１９９５，１５（...     

A Study on the Diagnostic Standard of Sinus Rhythm

ＡＳｔｕｄｙｏｎｔｈｅＤｉａｇｎｏｓｔｉｃＳｔａｎｄａｒｄｏｆＳｉｎｕｓＲｈｙｔｈｍ￥ＺｈａｎｇＦｅｎｆｕ；ＣｈａｉＹｕｙｉｎｇ；ＺｈｕＳｉｍｉｎｇ．ＡＣＴＡＡＣＡＤＥＭＩＡＥＭＥＤＩＣＩＮＡＥＮＡＮＪＩＮＧ１９９５，１５（２）：２５１（Ｄｅｐａｒｔ...     

178名农民膳食营养素与血压关系的多元分析

于金坛农村心血管病防治点３５～５９岁人群中，随机抽取１７８名进行春秋两季各连续３天的２４小时回忆法膳食周查、８小时夜尿钠钾及肌酐定量，同期测定血压取其６天均值。采用多元回归方法作个体每日营养素、夜尿钠钾排量与血压水平的相关分析，经摒除年龄、性别、体量指数（ＢＭＩ）、高血压家族史及饮酒习惯等因素后，其结果显示经总热量校正后的脂肪进食量及经肌酐校正后的尿钠排量与血压水平呈正相关，而进食总热量（ｋｃａｌ）则与其呈负相关。     

微量蛋白尿在妊娠高血压检验中的临床意义

目的:探讨妊娠高血压患者动态血压与微量蛋白尿的关系。方法:选择40例妊娠高血压患者,同时选择同期分娩的正常产妇40例,对两组进行动态血压监测(ABPM)、留24 h尿液检查尿微量蛋白质排泄率(UMAE)测定。结果:妊娠高血压组和对照组平均动脉压(MBP)、夜间平均收缩压、夜间平均舒张压、白昼平均收缩压、白昼平均舒张压、24 h平均收缩压、24 h平均舒张压、SBP负荷、DBP负荷比较,差异有统计学意义(P<0.05)。正常对照组尿微量蛋白质排泄率为12.5±5.3,妊娠高血压组尿微量蛋白质排泄率为49.1±28.5,两组比较差异有统计学意义(P<0.05)。结论:尿微量蛋白质可作为妊娠高血压患者肾脏损害的重要指标。     

Effects of genetic factors and dietary electrolytes on blood pressure of rural secondary school students in Hanzhong.

In this study, 24-h urine specimens were collected on 3 consecutive days from 181 adolescents (94 boys and 87 girls), aged 12-16 years, in a rural district--Hanzhong, Shaanxi Province, and sodium, potassium, calcium and magnesium levels were determined. Dietary intake of the four electrolytes and blood pressure were measured in children and their parents on the same consecutive days. The results were as follows: urinary output of calcium and magnesium might not be an appropriate index to reflect intake; after adjusting for age, sex, BMI, heart rate, and parental blood pressure, the ratio of dietary calcium to total calories was negatively related to diastolic blood pressure in the whole group, and the ratio of urinary calcium to creatinine was positively related to systolic blood pressure in girls; not only blood pressure but also its relation to electrolytes are affected by parental blood pressure after adjusting for age, sex, BMI and heart rate.     

社区原发性高血压病患者的血压变异性特征研究

目的　了解社区原发性高血压病患者的血压变异性（BPV）特征。方法　选取2016年12月—2017年6月在青岛市市北区延安路街道社区卫生服务中心门诊就诊的原发性高血压病患者130例。患者每个月至门诊随访1次,均随访超过3次。以收缩压变异系数（CV）表示BPV,计算患者随访期间的CV,并对不同平均收缩压、合并症、服药情况及是否有并发症患者进行比较。结果　是否有并发症及不同合并症患者的CV比较,差异无统计学意义（P>0.05）;不同平均收缩压、服药情况患者的CV比较,差异有统计学意义（P<0.05）。其中,平均收缩压为<160 mm Hg患者的CV低于平均收缩压≥160 mm Hg的患者,规律服药患者的CV低于未规律服药的患者,差异有统计学意义（P<0.05）。结论　平均收缩压和服药情况对长时BPV有影响,提示社区卫生工作者不仅应关注高血压患者的血压平均值,也应关注其BPV情况。     

原发性高血压患者血压晨峰现象与肾功能损害的相关性研究

目的：观察原发性高血压病患者晨峰血压对肾功能损伤的影响。方法应用24 h动态血压监测对206例轻中度原发性高血压病患者按晨峰血压分为年龄、性别无明显差异的晨峰组和非晨峰组。依据24 h尿微量白蛋白及肾功能生化测定,观察并比较患者晨峰血压对肾功能损伤的影响。结果晨峰组与非晨峰组患者24 h、日间、夜间SBP和DBP的血压平均值差异无显著性意义（P＞0.05）;晨峰血压两组差异有显著性意义（P＜0.01）,晨峰收缩压分别为（39.60±10.48） mmHg 和（15.94±10.07） mmHg,晨峰舒张压分别为（14.76±3.42） mmHg 和（10.37±8.83）mmHg;24 h尿微量白蛋白两组差异有显著性意义（P＜0.01）,晨峰组与非晨峰组分别为（105.95±26.06）mg/24h和（90.98±23.63）mg/24h;收缩压的晨峰血压与尿蛋白分泌呈明显正相关（r＝0.26,P＜0.01）,舒张压的晨峰血压与尿蛋白分泌无明显相关性（P＞0.05）;血肌酐、血尿素氮两组差异无显著性意义（P＞0.05）。结论原发性高血压病患者收缩压晨峰血压与高血压性肾脏损伤密切相关。     

拜新同对高血压患者血压变异性及微量尿蛋白的影响

目的观察拜新同对高血压患者血压变异性（BPV）及微量尿蛋白的影响。方法 60例原发性高血压患者随机分为非药物治疗组及拜新同治疗组,用药的第2周末做动态血压监测及检测24h微量尿蛋白（MAU）,观察BPV及对肾功能的影响。结果与非药物治疗组相比,拜新同治疗组的收缩压变异性下降（P〈0.05）,舒张压变异性改变不明显（P〉0.05）,24hMAU明显降低（P〈0.05）。24h收缩压变异性、白昼收缩压变异性与24hMAU含量均呈显著正相关。BPV与高血压性肾脏损害密切相关。结论拜新同可以降低原发性高血压患者的收缩压变异性,且可以降低蛋白尿的水平,具有肾脏保护作用。     

Dietary Potassium Intake and Renal Handling,and Their Impact on the Cardiovascular Health of Normotensive Afro-Caribbeans

Objective:

Recent nutritional profiles of dietary intake have indicated a shift from the ancient diet to the Western diet. The ancient diet provided high potassium and low sodium intake, which in turn led to sodium conservation and potassium excretion. This change in the dietary intake is expected to affect potassium and sodium handling in the kidneys. Numerous studies have been done to emphasize the importance of sodium handling by the kidneys and its impact on cardiovascular health. This study will investigate potassium intake and handling, and its impact on the cardiovascular health of a sample of normotensive Afro-Caribbeans by the possible modulation of the renin angiotensin aldosterone system (RAAS).

Methods:

A sample of 51 normotensive Afro-Caribbean participants was recruited for the study. Participants were observed over a two-day period in which they were given a 24-hour ambulatory blood pressure monitor and a container to collect blood pressure data and a 24-hour urine sample. Anthropometric measurements were noted. Urinary electrolytes and supine plasma renin activity (PRA) were determined from the 24-hour urine collection and a blood sample. Dietary potassium intake was estimated based on dietary intake observations, and calculated based on the urinary potassium excretion. SPSS version 19 was used to analyse the data to make inferences.

Results:

The daily potassium intake was observed to be 2.95 g/day and measured intake from the urinary potassium was between 4.95 and 7.32 g/day. Urinary potassium excretion was 3.66 (± 1.40) g/day. The urinary potassium excretion in the Afro-Caribbean sample in Barbados was higher than the other population samples. The averaged PRA of the participants (supine) was 0.778 (± 1.072) ng/mL/hour. The averaged nocturnal systolic blood pressure dip of the participants was 5.97 (± 4.324) %. There was no significant correlation between urinary potassium excretion, blood pressure, nocturnal systolic blood pressure dip and PRA.

Conclusions:

The Afro-Caribbean sample has an inadequate daily potassium intake based on the observed intake and recommended values, with a high urinary excretion of the electrolyte compared to other values in the literature. This high potassium excretion could have been partly due to low plasma renin activity levels in the study participants. As a possible consequence, an increase in the nocturnal peripheral resistance is a likely cause for the diminished systolic dip. The lack of correlations between dietary potassium excretion and the blood pressure parameters does not allow any firm inference of the electrolyte''s handling and its impact on cardiovascular health in the normotensive Afro-Caribbean participants. However, further research is needed to get a more accurate daily potassium intake value, and a more statistically robust sample to assess whether potassium handling and blood pressure would be affected by a change in potassium intake.     

Moderate potassium chloride supplementation in essential hypertension: is it additive to moderate sodium restriction?

Twenty patients with mild or moderate essential hypertension and not receiving any drug treatment, who had been moderately restricting their sodium intake to around 70 mmol(mEq) a day for at least one month and whose mean blood pressure was then 163/103 mm Hg, were entered into a double blind, randomised crossover study to compare one month's treatment with slow release potassium chloride tablets (64 mmol potassium chloride a day) with one month's treatment with a matching placebo. Mean (SEM) urinary sodium excretion on entry to the study was 68 (6.8) mmol/24 h. Mean urinary potassium excretion increased from 67 (6.9) mmol(mEq)/24 h with placebo to 117 (4.6) mmol/24 h with potassium chloride. Supine and standing systolic and diastolic blood pressures did not change significantly with potassium chloride supplementation when compared with pressures while receiving placebo or before randomisation. In patients who are able moderately to restrict their sodium intake doubling potassium as a chloride salt has little or no effect on blood pressure.     

低蛋白饮食状态下尿蛋白对临床期2型糖尿病肾病肾功能的影响

目的观察低蛋白饮食对临床期2型糖尿病肾病肾功能减退的抑制作用与尿蛋白水平和尿蛋白变化的关系。方法106例2型糖尿病患者,内生肌酐清除率（Ccr）在45ml/min以下,尿蛋白定量均〉0.3g/24h,血压靶目标值控制在130/80mmHg（1mmHg=0.133kPa）,饮食指导内容,摄入热量平均为（125.10±8.37）kJ/d,蛋白质为（0.66±0.05）g/d,钠（6.9±0.3）g/d,观察时间平均为（23±14）个月。根据观察期间蛋白质摄入量的平均值（DPI）的不同,把观察对象分为三组：Ⅰ组0.7g/（kg·d）以下,Ⅱ组0.7-0.9g/（kg·d）,Ⅲ组0.9g/（kg·d）以上。结果（1）比较好地遵守低蛋白饮食的Ⅰ组与Ⅱ、Ⅲ组比较,肾功能减退速度减慢,尿蛋白减少;（2）在尿蛋白水平相对一致的对象中,没有发现低蛋白饮食对肾功能减退有抑制作用;相反与蛋白质摄入量无关,尿蛋白量多的患者肾功能减退速度加快;（3）在观察开始时尿蛋白水平相对一致的基础上,不管是否比较好地遵守了低蛋白饮食,尿蛋白减少的幅度没有明显差异;（4）与DPI无关,观察开始时尿蛋白量与观察期间最小尿蛋白量之间的变化率和D-Ccr具有负相关关系。结论临床期2型糖尿病肾病肾功能不全患者,与饮食中低蛋白水平无关,尿蛋白水平和尿蛋白减少对肾功能的进展有影响;在评价低蛋白饮食对糖尿病肾病肾功能的影响时,要考察到尿蛋白在其中的作用。     

十二指肠空肠旁路术与全胃Roux-en-Y吻合术对大鼠水钠平衡的影响

目的 探讨十二指肠空肠旁路术（duodenal jejunal bypass,DJB）与全胃Roux-en-Y吻合术（Roux-en-Y reconstruction after total gastrectomy,RYTG）对SD大鼠水钠平衡的影响。方法 通过建立SD大鼠十二指肠空肠旁路术（DJB）与全胃Roux-en-Y吻合术（RYTG）及假手术3组手术模型,动态监测3组SD大鼠术前、术后1周、4周、8周体重、24h饮水量、尿量、及尿钠的情况。结果 与假手术组比较,SD大鼠接受不同的胃转流术后体重都有一定程度的下降,但RYTG组SD大鼠体重下降的幅度远大于DJB组;同时RYTG组术后24h饮水量、尿量、以及尿钠明显比同时期的DJB组高,而假手术组,无论在体重,还是术后24h饮水量、尿量、尿钠均无明显变化。结论 胃转流术后,SD大鼠24h饮水量、尿量、尿钠明显增加,RYTG组较DJB组增加更为显著,这些现象为胃转流术术后体内水钠平衡调节、体重下降,以及血压变化指明了研究方向,具有一定的参考意义。