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1.
从日本七叶树 Aesculus turbinata Blume.种子的 70%乙醇提取物中分得 4个三萜皂苷化合物,经光谱学分析鉴定了其中 2个化合物的结构,它们分别为:七叶皂苷Ⅰa:21β-巴豆酰基-22a-乙酸基原七叶皂苷配基-3β-O-[β-D-吡喃葡萄糖基(1-2)][β-D-吡喃葡萄糖基(1-4)]-β-D-吡喃葡萄糖醛酸(21β-tigloyl-22α-acetylprotoaescigenin-3β-O-[β-D-glucopyranosyl(1-2)][β-D-glucopyra-nosyl(1-4)]-β-D-glucopyra-nosiduronic acid)和七叶皂苷Ⅰb:21β-当归酰基-22α-乙酰基原七叶皂苷配基-3β-O-[β-D-吡喃葡萄糖基(1-2)][β-D-吡喃葡萄糖基(1-4)]-β-D-吡喃葡萄糖醛酸(21β-an-gelovl-22a-acetylprotoaescigenin-3β-O-[β-D-gluconyranosyl(1-2)][β-D-glucopyranosyl(l-4)]-β-D-glucopyranosiduronic acid),均为首次从日本七叶树  相似文献   

2.
Plasmaβ-endorphin(β-EP)levelsriseprogressivelythroughoutpregnancyandreachapeakatlabor[1].Thisendogenousopioidpeptidewasthoughttoplayaroleinmaintainingnormalpregnancyandproduceananalgesiceffectduringlabor[2].How-ever,thegeneralagreementconcerningthese…  相似文献   

3.
Thedrugresistanceofacutemyeloge-nousleukemiccells(AML)isamaincauseoftreatmentfailure.Theaffectingfactorsinvolvedintracellulardrugresistance,ki-neticsofanti-cancerdrug,abilityofdrugdiffusionandcapacityofleukemiccellgrowth,etc.[1].Thedetectionofdrugre-…  相似文献   

4.
IntroductionHUThasgreatclinicalvalueforthediagno-sisofunexplainedsyncope[1,2].HRPSDanaysisisanew,sensitive,quantitativeandnon...  相似文献   

5.
Inrecentyears,anewtendencyhasap-peared,whichwasconcernedwiththere-searchintoregulationofpancreaticsecre-tion.Researchofrecentyearshasindicatedinmanyrespectsthatvagusnervehasadi-rectregulativeeffectonexternalsecretionofpancreas[1].Inthisarticle,theDNA…  相似文献   

6.
Ofpotentialclinicalsignificance,syn-theticgrowthhormone(GH)-releasinghexapeptide(GHRP-6)isactiveafteroralandintranasaladministrationandthusholdspromiseasasimplifiedmeansofdirectlytreatingGH-deficiency[1].Consequently,therehasbeenmuchrecenteffortindev…  相似文献   

7.
3-烃基苯酞类化合物是一类存在于伞形科植物Cnidi umoficinale[1]、LigusticumWalichi[2]、Angelicaacutiloba[3]等植物中的有效成分,这些药用植物被广泛用在传统的中药方中,用来治疗妇科疾病及其它疾病...  相似文献   

8.
CimetidineisahistamineH2-receptorantagonist(H2RA)oficialyapprovedforclinicalusein1976totreatpepticulcer[1].Inrecentyears,thei...  相似文献   

9.
INTRODUCTION Pleckstrinhomology(PH)domainsarefunctionalregionsinmanysignalproteinsandcytoskeletalas-sociatedproteins.Althoughtheirfunctionisnotveryclear,mostoftheproposedfunctionsinvolvethelocalizationofpro-teinsonthecellmembrane[1]andthemediationofp…  相似文献   

10.
TwosignaltheoryforTcelactivationprovidedanewapproachfortumorgenetherapy[1-2].Expressionofcostimulatorymoleculegeneintransfect...  相似文献   

11.
眼科手术中眼心反射的研究进展   总被引:3,自引:0,他引:3  
在眼科手术及操作过程中,因刺激眼球或眼部组织而发生心率减慢、心律异常,伴有胸闷不适等症状称为眼心反射(ocularcardiacreflex,OCR)。1908年由Aschner和Dagnini首先报道,故又称Aschner′s-Dagnini′s反射[1]。1960年Mauinson等报告了1例斜视手术死于OCR,1962年Dea-cock等统计英国每年3500例眼科手术中,至少有45例因心脏停跳而死亡,且均为9岁以下儿童[2],1984年张一鸣报告1例严重眼心反射死亡[3]。此后,眼科学界对…  相似文献   

12.
Pinealectomyaffectsthediurnalvariationsin2-[~(125)I]iodomelatoninbindingsitesinchickenbursaofFabriciusZhaoYing(赵瑛);PoonAMS,Pa?..  相似文献   

13.
AlthoughthehumoralabnormalityhasbeenemphasizedinthepathogenesisofprematureovarianfailuresincethefirstreportofautologousantibodytoovaryinPOFpatientswasmadein1960byVallotonandhiscolleagues[1],recentlyaccumulat-edevidencesconcerningthevariationofTcellsu…  相似文献   

14.
Thegrowthofleukemiainsemisolidcultureinvitrowasdependentonthepres-enceofexogenousserum.Serumisamix-turecontaininglargenumberofunidentifiedchemicalcomponentsandunidentifiedbio-logicallyactivesubstances[1],whichprovidethenutrientsnecessaryforthecellgro…  相似文献   

15.
ThecoronaryarterycomplicationcouldbefoundinalmostalcasesofKawasakidisease[1].Ithasrecentlybeenshownthatplatelet-derivedgrowth...  相似文献   

16.
AnordrinisasteroidwithalossofonecarbonatomatAring(2α,17α-di-ethynyl-A-nor-androstane,2β,17β-dioldipropionate).Researchperformedprevious-lyhasdemonstratedthatithasantifertilityandterminationofearly-pregnancyfunc-tionobviously[1-3].Clinicalobservationc…  相似文献   

17.
Hydroxyapatite(HAP)isaninorganiccompoundcomposedofcalciumandphos-phoruswithamolecularformulaofCa10(PO4)6(OH)2andmolecularweightof1004.8.Ithasgoodstability,compatibilitywithtissues[1]andadsorption[2].WechosetheparticleofHAPwithdiameterof2mmasthecarrie…  相似文献   

18.
Inrecentyears,oneofthemostexcit-ingadvancesintheresearchesofpituitaryadenomasisthediscoverythat30%-40%ofhumanpituitarysomatotrophinomascarrysomaticmutationsofthegenefortheα-subunitofthestimulatoryGTP-bindingprotein,Gs(Gsα)[1].Thecancergeneresult-ingf…  相似文献   

19.
CD44wasoriginallyimplicatedasa“hom-ing”receptordirectingthemigrationofrecir-culatinglymphocytes[1].CD44expressionhadbeenconfirmednotonlyinlymphocytesbutal-soinawidevarietyofepithelialtissues.Itisconsideredasanimportantcelladhesionmoleculeforcelltocel…  相似文献   

20.
RT-PCRamplificationoftumor-asso-ciated(carcinoembryonicantigen)and(or)organ-specific(cytokeratin19)mRNAhasbeenusedmainlyforthedetectionofcircu-latingtumorcellsandmicrometastasesinsolidtumors[1].Originally,theproductofamplificationwasanalyzedbygelelec…  相似文献   

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