大型岩斜脑膜瘤的显微手术治疗

目的　对 12例大型岩斜脑膜瘤行乙状窦前入路的显微手术治疗 ,探讨该入路治疗岩斜脑膜瘤的要点。方法　总结岩斜脑膜瘤的临床表现、神经影像学特征和术中要点。结果　肿瘤全切除 10例 ,次全切除 1例 ,大部切除 1例 ,术后好转率 83.3%。结论　大型岩斜脑膜瘤首选乙状窦前入路 ,掌握术中暴露要点和分离技巧可提高手术疗效     

乙状窦前入路治疗岩斜区肿瘤9例报告

对9例岩斜区肿瘤患者采用经乙状窦前入路的手术治疗。结果6例肿瘤全切除,2例次全切除,1例大部分切除。术后症状改善6例。提示乙状窦前入路能最大限度地暴露乙状窦前空间,充分暴露岩斜区肿瘤,是岩斜区肿瘤的首选手术入路。     

岩斜区脑膜瘤的显微外科治疗

目的：探讨显微手术切除岩斜区脑膜瘤的手术方法及术后疗效，总结临床治疗经验。方法：通过回顾分析我科1997年8月～2006年3月经显微切除19例岩斜区脑膜瘤的临床资料，主要采用岩骨乙状窦前入路、颞下经小脑幕入路、乙状窦后入路3种入路。结果：肿瘤全切除12例（63．2％），5例次全切，2例大部分切除，均无严重并发症发生。结论：术前充分准备、选择合适的手术入路和娴熟显微外科技术可以提高岩斜坡区脑膜瘤的切除率，减少并发症的发生，降低病死率。     

乙状窦前人路治疗岩斜区肿瘤9例报告

对9例岩斜区肿瘤患者采用经乙状窦前入路的手术治疗。结果6例肿瘤全切除，2例次全切除，1例大部分切除。术后症状改善6例。提示乙状窦前入路能最大限度地暴露乙状窦前空间，充分暴露岩斜区肿瘤。是岩斜区肿瘤的首选手术入路。     

改良颞下一经小脑幕入路显微手术切除岩斜区脑膜瘤

目的 探讨改良颞下一经小脑幕人路显微手术切除岩斜区膜瘤瘤的显微手术技术.方法 在传统颞下一经小脑幕人路的基础上,离断颧弓切除Labbe氏静脉前颞下回脑组织.采用显微外科技术切除岩斜区脑膜瘤7例.结果 肿瘤全切除2例,次全切除3例,大部分切除2例.术后肢体轻瘫2例.面神经和动眼神经不全麻痹各1例,无手术死亡.随访8～36个月,2例恢复良好,4例生活自理,1例生活需要照顾.结论 改良颞下一经小脑幕入路具有操作简单,创伤小,易于掌握,特别适用于中上斜坡脑膜瘤手术,是切除岩斜区脑膜瘤较理想的手术入路.     

改良颞下-经小脑幕入路显微手术切除岩斜区脑膜瘤

目的探讨改良颞下-经小脑幕入路显微手术切除岩斜区膜瘤瘤的显微手术技术。方法在传统颞下-经小脑幕入路的基础上，离断颧弓切除Labbe氏静脉前颞下回脑组织。采用显微外科技术切除岩斜区脑膜瘤7例。结果肿瘤全切除2例，次全切除3例，大部分切除2例。术后肢体轻瘫2例。面神经和动眼神经不全麻痹各1例，无手术死亡。随访8～36个月，2例恢复良好，4例生活自理，1例生活需要照顾。结论改良颞下-经小脑幕入路具有操作简单，创伤小，易于掌握，特别适用于中上斜坡脑膜瘤手术，是切除岩斜区脑膜瘤较理想的手术入路。     

岩斜区脑膜瘤显微手术入路的改良及疗效

目的探讨改良经岩骨乙状窦前入路显微手术切除岩斜区脑膜瘤的疗效及手术技巧.方法采用改良经岩骨乙状窦前入路显微外科切除岩斜区脑膜瘤11例并对其临床资料进行回顾性分析.结果肿瘤全切除8例,次全切除1例,大部切除2例.本组无死亡病例,术后昏迷 1 例,新出现暂时性颅神经障碍3例,无脑脊液漏发生.结论改良经岩骨乙状窦前入路简便、安全,可充分显露岩斜区,有利于提高肿瘤切除程度和术后疗效,是岩斜区脑膜瘤手术治疗的较佳入路,但对术者的手术技巧和经验要求较高.     

岩斜区脑膜瘤显微手术入路的改良及疗效

目的探讨改良经岩骨乙状窦前入路显微手术切除岩斜区脑膜瘤的疗效及手术技巧.方法采用改良经岩骨乙状窦前入路显微外科切除岩斜区脑膜瘤11例并对其临床资料进行回顾性分析.结果肿瘤全切除8例,次全切除1例,大部切除2例.本组无死亡病例,术后昏迷 1 例,新出现暂时性颅神经障碍3例,无脑脊液漏发生.结论改良经岩骨乙状窦前入路简便、安全,可充分显露岩斜区,有利于提高肿瘤切除程度和术后疗效,是岩斜区脑膜瘤手术治疗的较佳入路,但对术者的手术技巧和经验要求较高.     

乙状窦前入路手术切除岩斜区肿瘤20例

岩斜区肿瘤因其位置深在且与颅神经、基底动脉及脑干关系密切,致手术难度很大。本院自1999年以来采用乙状窦前入路显微神经外科手术切除20例岩斜区肿瘤,效果良好,报道如下。     

颞-枕下-经岩骨入路切除岩斜区肿瘤116例报告

目的介绍采用颞-枕下-经岩骨入路切除岩骨斜坡区肿瘤的手术方法。方法分析116例岩斜区肿瘤患者的手术方法,所有病人均采用颞-枕下-经岩骨入路切除肿瘤,其中采用经迷路后-乙状窦前入路110例,经乙状窦入路2例,经迷路-乙状窦前入路2例,经颧弓-经岩骨入路2例。结果肿瘤全切除75例(64.7%),次全切除33例(28.4%),大部切除8例(6.9%)。手术死亡3例,占手术总数2.6%。结论颞-枕下-经岩骨入路适用于病变位于斜坡中线部位,或肿瘤横跨颞骨岩部内侧,侵及中、后颅凹和累及海绵窦、三叉神经切迹(Meckel凹陷)肿瘤的切除,该方法在术中对岩骨斜坡区能够获得良好的暴露。     

侵入海绵窦的岩斜脑膜瘤的手术治疗

目的 探讨侵入海绵窦的岩斜脑膜瘤的临床特点、手术策略、手术技巧和治疗效果.方法　回顾性分析2004年4月至2009年3月南昌大学第一附属医院临床资料完整的15例侵入海绵窦的岩斜脑膜瘤病例,总结其临床特点.本组均采用经乙状窦前入路,手术策略为全切除岩斜区肿瘤,对侵入海绵窦内的肿瘤行次全切除,术后辅以γ刀治疗.分析手术后颅神经功能和病人生存状况.结果头痛头晕、外展麻痹和面部麻木为本病的主要症状.手术近全切除肿瘤13例,切除≥90%2例.12例残余肿瘤术后行γ刀治疗.无手术死亡,术后无新增颅神经损害6例,出现动眼神经麻痹6例,面部麻木7例,外展功能障碍4例,面瘫7例.随访6～59个月(平均38.6个月),12例恢复正常工作和生活,2例生活自理,1例生活需他人照顾.13例无肿瘤复发,2例残余肿瘤增大者中1例经γ刀治疗肿瘤生长得到控制.眼球运动和上睑下垂均完全恢复,面瘫基本恢复,面部麻木5例部分缓解,外展功能障碍无明显改善.结论对侵人海绵窦的岩斜脑膜瘤应采用合理的手术策略,尽可能减少手术引起的神经损害,有利于提高病人的生存质量.     

Subtemporal transpetrosal apex approach: study on its use in large and giant petroclival meningiomas

Background  The subtemporal transtentoral approach has been reported for nearly two decades; however it was not well used due to some limitations in dealing with large and giant petroclival meningiomas. The clinical outcome and merit of the modified subtemporal transpetrosal apex approach in large and giant petroclival meningiomas, as well as the choices, the improvements and the therapy strategies of the microsurgical approach in such patients were evaluated in this study.

Methods  Totally 25 cases of large and giant petroclival meningiomas undergone the modified subtemporal transpetrosal apex approach between April 2004 and January 2010 were enrolled in this study. The choice and improvement of the approach, the basis of anatomy and related research, the effect of accessory equipment, the exposure of tumor and the changes of neurofunction pre- and post-operation were all reviewed retrospectively. The operation outcomes and complications in this approach were also compared with those in the transpetrous presigmoid approach done in 14 cases in the same period.

Results  All 25 cases underwent the modified subtemporal transpetrosal apex approach under electrophysiologic monitoring of cranial nerves and brain stem function. Trochlear nerve was partly wrapped in 14 cases, totally wrapped but can be explored in the initial segment of the cerebellum tentorium in 8 cases, totally wrapped and could not be seen until tumor was partly removed in 3 cases. The cerebellum tentorium was cut along the temporal bone from the anterior part of the apex to the mastoid part of superior petrous sinus in 6 cases, from the posterior part of the apex to the mastoid part of superior petrous sinus in 19 cases. Gross tumor resection was accomplished in 17 (68%) patients, subtotal resection in 7 (28%) patients, and partial resection in 1 (4%) patient. The most common postoperative complication was new neurological deficits or aggravations of preexisting deficit (64%). Follow-up ranged from 3 to 69 months. Compared with the transpetrous presigmoid approach done in 14 cases in the same period, the modified subtemporal transpetrosal apex approach showed obvious advantages such as simplicity in manipulating, microinvasiveness, less time-consuming, less complication, higher rate of tumor resection though the rates of gross tumor resection might be of no significant difference.

Conclusions  Modified subtemporal transpetrosal apex approach has obvious advantages compared with the transpetrous presigmoid approach. Some complications need to be solved by practice and modification of the approach as well as the accumulation of the experiences.

     

Keyhole approach surgery for petroclival meningioma

Background In China, the feasibility of keyhole approach in surgical treatment of petroclival meningioma has not been well evaluated. This report summarized our experience in 25 patients with petroclival meningioma who had been treated with keyhole approach surgery. Methods From July 2000 to July 2005, 25 patients with petroclival meningioma were subjected to resection via subtemporal, retrosigmoid or combined keyhole approaches. The extent of tumor resection was evaluated by MRI 3 months after surgery, and postoperative complications were investigated. Results The maximum diameter of tumors ranged from 2 to 7 cm （mean, 4.5 cm）. Gross total resection （GTR） was achieved in 14 patients, giving a GTR rate of 56%. Subtotal resection （STR） was carried out in 8 patients and partial resection in 3. Thirteen patients kept normal neurological status, whereas others suffered from cranial nerve deficits （Ⅶ, Ⅶ, Ⅲ and lower CN）. One patient died in the postoperative period. Conclusions Keyhole approach surgery, especially the combined keyhole approach is suitable for the treatment of petroclival meningioma. It provides easy and quick access to the supra- and infratentorial juxta-clival region without drilling of the petrous bone. Complications related to the approach can be minimized.     

岩斜区肿瘤手术入路的选择

目的总结岩斜区肿瘤3种不同入路优缺点,探讨选择手术入路应考虑的因素,以及如何选择入路,并对临床效果进行分析。方法回顾性分析2004—2014年手术切除岩斜区肿瘤21例临床资料,手术入路包括：枕下乙状窦后入路、乙状窦前入路和颞下经小脑幕入路3种,从肿瘤性质、生长方式、术后并发症和操作难度等因素进行分析,总结选择手术入路时如何依据这些因素对3种入路进行选择,观察依据这些因素指导手术入路选择的临床效果,分析正确选择手术入路对保护神经功能、提高患者生存质量,提高手术效果的作用。结果本组21例,全切16例,次全切4例,部分切除1例。神经鞘瘤6例,表皮样囊肿3例,脑膜瘤12例。术后1例为乙状窦前入路,术后出现脑脊液耳漏,颅内发生化脓性感染,治疗无效死亡;5例出现患侧滑车神经损伤,有复视;6例周围面神经瘫痪;1例出现颞叶脑内血肿,经过保守治疗后,血肿吸收,正常出院;3例出现运动性失语,经治疗后,渐好转;3例出现手术区皮下积液并有反复低热,给予留置腰大池治疗,无临床症状出院,1~2月随访,体温正常,积液消失。5例肿瘤残留术后进行放射治疗,未有复发。结论手术入路所经过的解剖结构不同,暴露范围分别有侧重点,术前应当综合考虑各种因素,选择最适合患者入路,这样可以最大限度保护周围组织,提高手术成功率。     

改良经岩骨乙状窦前入路显微外科治疗岩斜区肿瘤

目的探讨岩斜区肿瘤经改良岩骨乙状窦前入路显微外科治疗的手术特征及并发症。方法回顾性分析经显微手术治疗的9例岩斜区肿瘤,对肿瘤临床和影像学特征、手术入路、手术切除技巧及术后常见并发症的处理进行研究。结果肿瘤全切除7例,近全切除1例,大部切除1例。术后一过性失语1例,脑水肿2例,周围性面瘫1例,脑脊液耳漏1例,腰穿引流后好转。无死亡病例。结论改良经岩骨乙状窦前入路可充分暴露岩斜区肿瘤及其周围结构,是岩斜区肿瘤的较佳手术入路。     

PARAPETROSAL PRESIGMOID APPROACH FOR PETROCLIVAL TUMORS

Petroclivaltumorsrepresentmoredifficultto radicalresection.Thesetumorsarelocateddeepat skullbase,usuallywithabundantbloodsupplyand broadattachmenttothepetrous,clivus,andtentori um.Sometimesthetumorinvadesintothecavernous sinusandthevitalperforatingarteries,cranial nerves,andthebrainstemareinvolved[1].Inthepastdecade,withtheadventofskullbase surgeryconcept,moreandmoresurgeonsreported successfulcasesofpetroclivaltumorremoved.Over all,therehasbeenadecreaseinpostoperativemor talityandmorbidity.Se…     

内侧型蝶骨嵴脑膜瘤显微外科治疗体会

目的 :探讨内侧型蝶骨嵴脑膜瘤手术治疗方法。方法 :本文复习了 2 0例内侧型蝶骨嵴脑膜瘤的临床资料 ,重点讨论了手术方法。结果 :实现脑膜瘤镜下全切 17例 ,大部分切除 3例 ,无手术死亡 ,疗效满意。结论 :认为在熟悉掌握毗邻显微解剖结构的基础上 ,采用显微外科技术 (CUSA) ,结合术前超选栓塞颈外动脉系统的肿瘤供应支 ,可提高肿瘤全切率 ,减少对周围重要神经结构的损伤 ,降低死亡率。但对明显侵犯下丘脑、海绵窦等重要结构的肿瘤 ,手术难度较大者 ,尚应考虑姑息的手术方式     

岩斜脑膜瘤15例手术治疗分析

目的探讨岩斜脑膜瘤的临床特点、手术策略、手术技巧和治疗效果。方法回顾性分析临床资料完整的15例岩斜脑膜瘤病例,总结其临床特点。本组均采用经Kawase入路,手术策略为全切除岩斜区肿瘤,术后辅以γ刀治疗。分析手术后颅神经功能和患者生存状况。结果头痛头晕、外展麻痹和面部麻木是岩斜脑膜瘤的主要症状。手术近全切除肿瘤13例,次全切除2例。12例残余肿瘤术后行γ刀治疗。无手术死亡,术后无新增颅神经损害6例,出现动眼神经麻痹6例,面部麻木7例,外展功能障碍4例,面瘫7例。随访6~59个月(平均38.6个月),12例恢复正常工作和生活,2例生活自理,1例生活需他人照顾。13例无肿瘤复发,2例残余肿瘤增大者中1例经γ刀治疗肿瘤生长得到控制。动眼神经麻痹和面瘫均改善,面部麻木5例部分缓解,外展功能障碍无明显改善。结论对岩斜脑膜瘤应采用合理的手术策略,尽可能减少手术引起的神经损害,有利于提高患者的生存质量。     

经侧方入路切除岩骨-斜坡区肿瘤

目的 探讨经侧方入路切除斜坡肿瘤的治疗效果。方法 对６１例岩骨斜坡区肿瘤患者分别采用以下手术入路：（１）改良翼点入路;（２）颞枕经天幕,岩骨入路;（３）经岩骨乙状窦前幕上,下联合睡;（４）远外侧经髁入路。结果 ６１例岩骨－余坡区肿瘤,全切５４例,近全切除６例,大部切除１例,无手术死亡。６１例中,其中有３７例患者术后得到了随访,结果满意。