Ticlopidine hydrochloride is a platelet aggregation inhibitorthat is used for the prevention of vascular thrombosis. So far,only six cases of ticlopidine-induced lupus have been documentedin the literature [1–3]. We report here a first case ofticlopidine-induced lupus with renal involvement.   A  相似文献      Patients with end-stage renal disease who require chronic dialysisare at high risk of developing malignancy. There are many reportedcases of the development of renal or urothelial cancer in suchpatients [1–8]. We report the first case, to our knowledge,of multifocal, invasive transitional cell carcinoma (TCC) andunilateral renal cell carcinoma (RCC) with acquired cystic disease,occurring simultaneously in a patient on haemodialysis treatedby complete urinary tract exenteration. Our patient was managedsuccessfully with an aggressive treatment.   A 69-year-old man was referred to our institution  相似文献      Paradoxical embolism is a rare cause of severe renal arteryocclusion and is frequently under-diagnosed [1]. Rapid endovascular intervention with minimal morbidity may makeclot removal possible and reverse organ function [2,3]. We present here the case of a patient with an acute renal failuredue to a bilateral renal artery paradoxical embolism that wassuccessfully treated by a modified standard technique of anendovascular procedure, with a rapid mechanical and local pharmacologicalthrombolysis. The patient partially recovered her renal functionand was able to stop dialysis.   A 70-year-old female with a past medical history of type IIdiabetes, hypertension and dyslipidaemia was admitted for pulmonaryembolism associated with a recurrent deep vein thrombosis ofthe right lower extremity. The anti-coagulation treatment wasinitially well tolerated, but had to  相似文献      Renal transplant patients remain at risk of graft loss due toacute rejection, calcineurin inhibitor toxicity and chronicallograft nephropathy. Less frequent causes include opportunisticinfections related to immunosuppressive therapy. However, infectionsare a major clinical issue in the field of renal transplantation,impacting on graft and patient survival. Fungal infections accountfor about 5% of infections in renal transplant recipients [1].Candida species are the most common fungal pathogen, and themost common forms of infection are oral and esophageal candidiases,vascular access device-related and urinary tract infections[2]. The incidence of candidiasis of the renal allograft israre and not very well documented.   A 50-year-old white female with a prior medical history of hypertension,  相似文献      Severe acute respiratory syndrome (SARS)-associated coronavirus(SARS-CoV) has been identified as the causal agent of SARS.Although not common, acute renal failure (ARF) in SARS patientsusually has a catastrophic outcome, with a mortality rate of77% [1]. The causes of ARF in association with SARS are unknown.An increase in creatine kinase (CK) may play a role [2]. Wepresent two patients who met the definition of probable SARS.   A 78-year-old man  相似文献      Acute renal failure due to phosphate nephropathy following bowelcleansing with an oral sodium phosphate solution is a rare,but well-known, complication [1]. Several authors have reporteddiffuse tubular injury and tubular deposition of calcium phosphatein biopsies taken from such patients [1–4]. In these patients,the term acute phosphate nephropathy more aptly describes thisentity than the previously used term acute nephrocalcinosis[1]. It has been a matter of debate whether these changes aredirectly induced by the phosphate load or whether they werebeing present before the procedure [3]. We, therefore, reporta patient with acute phosphate nephropathy who had kidney biopsiestaken before and after bowel cleansing with sodium phosphate.   In 2002, a 69-year-old woman was  相似文献      Haemodialysis access graft is so important as to be called alifeline for the patient on maintenance haemodialysis. The vascularaccess problem is the leading cause of admission in patientswith end-stage renal disease. Many complications of the prostheticvascular access graft are reported, such as graft thrombosis,infection, aneurysm or pseudoaneurysm, and arterial steal syndrome[1]. We recently experienced two cases of graft thrombosis relatedto the iatrogenic fistula between haemodialysis access graftand autogenous vein at the needling site during haemodialysis.We report our cases with their clinical manifestation and thetreatment outcome and possible methods of prevention [2].   A 76-year-old female on long-term haemodialysis  相似文献      Jaccoud was a French clinician from the 19th century who reporteda peculiar joint deformity in patients with rheumatic fever[1]. He observed the development of an ulnar deviation thatwas reducible, which indicated that the joint spaces were notdestroyed. We have no evidence that Jaccoud was interested inthe kidney or that he ever saw a patient with nephritis. Perhapsthe patient reported here would have raised his interest inour specialty.   A 69-year-old woman was admitted because of generalized weaknessand decreasing renal function. Two months earlier, her  相似文献      Common causes of gross haematuria include stones, neoplasms,tuberculosis, trauma and prostatitis. However, macroscopic haematuriacan occur in patients with IgA nephropathy. IgA nephropathyusually occurs in patients under 40 years of age, and loin painoften accompanies the haematuria [1]. Furthermore, macroscopichaematuria in IgA nephropathy often causes acute renal failurebecause of tubular obstruction by red blood cells [2–4].Obstruction or haematoma of the renal pelvis and lower urinarytract by gross haematuria in IgA nephropathy or any other diseasescausing haematuria has not been reported. Here, we report thecase of a patient with pelvic haematoma in IgA nephropathy,that was erroneously suspected for pelvic malignancy leadingto its radical resection.   A  相似文献      Tenofovir is an antiviral nucleotide with activity against humanimmunodeficiency virus type I (HIV-1). Tenofovir is extensivelyand rapidly excreted in the urine by the kidneys [1]. Thereare no available data on tenofovir pharmacokinetics in patientswith renal failure. We report here on the clinical effects andthe pharmacokinetics of tenofovir in one patient with end-stagerenal disease (ESRD) undergoing haemodialysis.   The patient was a 46-year-old Caucasian man co-infected withHIV-1 and hepatitis B virus (HBV) who was undergoing haemodialysistwice a week for end-stage renal failure (ESRD) secondary toautosomal polycystic kidney disease. At the time of the study,his creatinine clearance was 10 ml/min with a urinary outputof  相似文献      Pregnancy in women with end-stage renal disease (ESRD) undergoingdialysis treatment is uncommon but increasingly observed overthe last few years [1]. The outcome in pregnancies in dialysedwomen is greatly influenced by maternal risk factors. Duringgestation, various risks may appear including the mother's fluidoverload, hypertension, anaemia and an increased risk for fetaland perinatal complications such as neonatal mortality, prematurityand small-for-gestational-age [2,3]. Here, we report on a 40-year-oldfemale patient who developed ESRD due to an extended Stanford-B-aneurysmof the aorta 1 year prior to conception. Nonetheless, the childwas delivered successfully by caesarian section after 31 weeksof gestation.   A 39-year-old female was referred to our centre with a hypertensivecrisis, dizziness,  相似文献      Polytetrafluoroethylene (PTFE) grafts are widely used to facilitateaccess for haemodialysis. They may present with complicationsincluding infection and thrombosis. However, localised lymphomaassociated with a PTFE graft has not been previously described.Here we present the case of a patient with B-cell lymphoma arisingaround a PTFE graft.   A 77-year-old Italian woman with end-stage renal failure ofunknown origin had been on haemodialysis since 1995. Her past  相似文献      Primary renal glucosuria (OMIM 233100) is defined by an increasedurinary glucose excretion in a patient with a normal blood glucoseconcentration in whom all other filtered substrates are handledcompletely normally by the proximal tubules. Mild renal glucosuriais a relatively common condition that was first studied at thebeginning of the last century [1], but it was not until 1987that a study on a patient with virtual absence of renal tubularglucose reabsorption was published. This condition has beentermed type 0 renal glucosuria [2]. Here we report on the long-termhistory of this patient whose underlying genetic defect hasrecently been identified [3,4].   Patient P.M., a male of German descent, was born in  相似文献      Early renal transplant dysfunction can be caused by acute rejection,acute tubular necrosis (ATN), infection, ciclosporin toxicity,bleeding, urethral obstruction, urinary leak, lymphocele andthrombosis [1]. Prompt treatment of early allograft dysfunctionis essential and therefore accurate diagnosis mandatory. Wedescribe a patient with an unusual cause of allograft dysfunction,which was resolved by a simple surgical intervention.   A 32-year-old man with congenital blindness, hypertension andend-stage renal disease underwent renal transplantation. Hehad been haemodialysis-dependant since the age of 24 years.Dialysis was performed through an  相似文献      Endovascular repair of an abdominal aortic aneurysm (AAA) istoday a widely accepted alternative to conventional open surgicaltreatment, especially in patients with a high risk of complications[1]. We describe a case of acute renal failure following theimplantation of an endograft in a patient  相似文献      A wide spectrum of primary glomerular diseases may occur inpatients with type 1 diabetes mellitus (DM) due to autoimmunemechanisms [1,2]. We here report a patient with type 1 DM andHashimoto's thyroiditis who developed membranoproliferativeglomerulonephritis (MPGN).   A 35-year-old man with type 1 DM for 18 years and Hashimoto'sthyroiditis for 6 years was referred to  相似文献      We report the case of a 43-year-old renal transplant recipientwho required ventilatory support for acute respiratory tractinfection. The differential diagnosis in immunocompromised individualsis extensive and requires prompt investigation.   A 43-year-old male non-smoker with end stage kidney failuredue to medullary cystic kidney disease received a 1:1:1 cadavericrenal allograft in 2001. The transplant initially functionedwell, but 1 month after transplantation, his renal functionworsened and a renal transplant biopsy showed mild cellularrejection. He was treated with methylprednisolone (500 mg/dayfor 3 days) and his renal function improved to a baseline creatinineof 160 µmol/l. He subsequently had a cytomegalovirus (CMV)seroconversion illness with diarrhoea and deterioration in renalfunction. This was successfully treated with ganciclovir. For the next 3 years he experienced no medical problems andhis  相似文献      Sarcoidosis is a multisystem disorder of unknown aetiology characterizedby the accumulation of lymphocytes, mononuclear phagocytes,and non-caseating granulomas in involved tissues. Renal involvementleading to renal function deterioration in sarcoidosis is rare:it is observed in <10% of patients. In the relevant literature,there have been only a few cases of sarcoidosis recurrence inrenal allograft recipients published. We present here the firstcase of sarcoidosis recurrence in renal allograft during pregnancy.   A 27-year-old woman was diagnosed with sarcoidosis at age 14by lacrimal and parotid gland biopsy. Initial therapy did notinclude steroids as no pulmonary or other organ involvementwas documented. However, hypertension and renal insufficiency(serum creatinine [sCr] 300  相似文献      Hereditary renal disease is not an uncommon cause of end-stagerenal failure (ESRF) and accounts for 15.7% of the patientsin the Irish dialysis population [1]. Adult polycystic kidneydisease was the underlying diagnosis in the majority (68%) ofthese individuals. Although familial interstitial nephritisis rare, we have previously reported two siblings who developedESRF as a consequence [2]. They also had retinitis pigmentosabut did not fit into any previously described renal-retinalsyndrome. Both patients have since undergone successful cadavericrenal transplantation but have subsequently developed recurrenceof their disease with ultimate graft loss. The implicationsof these findings are discussed.   A 16-year-old female was admitted with worsening night blindnessand renal failure in 1988. She was obese and her IQ was estimatedat 130 using the Wechsler Adult Intelligence Scale  相似文献      Overlapping of different glomerulopathies has already been observedin renal biopsies from diabetic as well as non-diabetic patients[1]. Unlike other reports, the present paper describes a patientwhere two distinct forms of immunological glomerulonephritiswith a different histological and clinical picture occurredseparately at some years’ interval from each other. Thisfinding suggests an individual susceptibility of the patientto immunological renal injury and gives food for speculationon the pathogenesis of glomerulonephritis.   The patient here described was born in Southern Italy in 1966.Family investigation proved negative for glomerular diseases,renal failure, arterial hypertension and diabetes mellitus.In 1991, when he was 25 years old, he had an episode of macroscopichaematuria during an upper airways infection, and this recurredin November 1994, at the age of 28. At that time, urinalysisrevealed haematuria  相似文献   

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共查询到20条相似文献，搜索用时 281 毫秒 1. Ticlopidine-induced lupus with renal involvement.      Takayasu Ohtake  Shuzo Kobayashi  Koji Okamoto  Machiko Oka  Kyoko Maesato  Takeo Yasu  Hidekazu Moriya 《Nephrology, dialysis, transplantation》2006,21(7):1992-1993	Introduction	Case	Introduction	Case	Introduction	Case report	Introduction	Case report	Introduction	Case 1	Introduction	Case report	Introduction	Case 1	Introduction	Case	Introduction	Case	Introduction	Case	Introduction	Case	Introduction	Case	Introduction	Case	Introduction	Case report	Introduction	Introduction	Case	Introduction	Case report	Introduction	Case	Introduction	Case 1	Introduction	Case

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