以重症肺炎入院确诊艾滋病3例病例分析

目的提高非感染科医生对艾滋病（AIDS）的早期识别能力,减少误诊。方法回顾性分析总结望京医院呼吸科2011年6月-2013年1月期间确诊的3例因重症肺炎住院治疗的AIDS患者的临床特点。结果 AIDS发生肺部感染时病情重,3例均诊断为卡氏肺孢子虫（PCP）肺炎,均合并Ⅰ型呼吸衰竭,影像学均表现为间质感染,同时合并口腔念珠菌感染,与普通社区获得性肺炎（CAP）不同。结论 AIDS患者症状、影像学改变与体征不匹配,其发病特点、影像学表现与普通CAP有明显差别,据此可以提高AIDS的早期诊断率。     

18例确诊和疑诊儿童艾滋病的临床分析

目的:分析比较确诊和疑诊儿童艾滋病(Acquired immunodeficiency syndrome,AIDS)患者的临床特征.方法:对2006年4月～2009年9月收治8例确诊AIDS患者和10例疑诊AIDS患者的临床资料进行分析比较.结果:两组患者临床症状多出现在婴幼儿阶段;大多数来自农村,其父母相关病史对儿童...     

Improved short-term survival of AIDS patients initially diagnosed with Pneumocystis carinii pneumonia, 1984 through 1987

I analyzed trends in the survival of 36,847 adults who were diagnosed with acquired immunodeficiency syndrome between January 1984 and September 1987 under the pre-1987 surveillance definition of acquired immunodeficiency syndrome. For patients in whom Pneumocystis carinii pneumonia was among the first manifestations of acquired immunodeficiency syndrome, the estimated 1-year survival increased from 42.7% for those diagnosed in 1984 and 1985 (95% confidence interval, 41.5% to 44.3%) to 54.5% for those diagnosed in 1986 and 1987 (95% confidence interval, 53.7% to 55.7%). The gain in survival was observed in homosexual men and intravenous drug users of both sexes, in all age and racial groups, in all geographic regions, and in patients with and without coexisting initial diagnosis. Reduced mortality in the 3-month period immediately following the initial diagnosis of acquired immunodeficiency syndrome contributed little to the overall gain in survival. No gain in survival was seen for patients in whom P carinii pneumonia was not an initial manifestation of acquired immunodeficiency syndrome. It is unlikely that the observed improvements in survival resulted solely from errors in death reporting. Better diagnosis and treatment, particularly the introduction of zidovudine in 1986, may have contributed to the decline in mortality.     

河南省116例首诊艾滋病患者抗病毒治疗免疫学效果评价

目的分析河南省2009年首诊为艾滋病(AIDS)后随即接受抗病毒治疗的患者CD4+T淋巴细胞计数的变化情况。方法收集河南省艾滋病检测实验室网络数据库登记的116例河南省2009年首诊为AIDS后当年即接受抗病毒治疗的患者资料,将其按照治疗前CD4+T淋巴细胞数分成3组(<20个/μl,20~99个/μl和100~350个/μl),使用SPSS 14.0软件对患者治疗前、治疗后约2个月及5个月的CD4+T淋巴细胞数进行统计学分析。结果首诊后接受治疗的3组患者在治疗约2个月后CD4+T细胞计数同治疗前比较都有提高[<20个/μl组:(84.93±64.33)个/μlvs(9.39±5.10)个/μl,P=0.000;20~99个/μl组:(178.71±135.34)个/μlvs(46.62±18.71)个/μl,P=0.001;100~350个/μl组:(316.81±128.81)个/μlvs(197.66±67.59)个/μl,P=0.002],但是在治疗5个月后3组患者CD4+T细胞计数同治疗2个月时比较差异均无统计学意义。治疗前CD4+T细胞基线低的组达到的治疗效果较差。结论早发现、早治疗仍应是河南省开...