Effects of submaximal and supramaximal interval training on determinants of endurance performance in endurance athletes

We compared the effects of submaximal and supramaximal cycling interval training on determinants of exercise performance in moderately endurance‐trained men. Maximal oxygen consumption (VO_2max), peak power output (P_peak), and peak and mean anaerobic power were measured before and after 6 weeks (3 sessions/week) of submaximal (85% maximal aerobic power [MP], HIIT₈₅, n = 8) or supramaximal (115% MP, HIIT₁₁₅, n = 9) interval training to exhaustion in moderately endurance‐trained men. High‐intensity training volume was 47% lower in HIIT₁₁₅ vs HIIT₈₅ (304 ± 77 vs 571 ± 200 min; P < 0.01). Exercise training was generally associated with increased VO_2max (HIIT₈₅: +3.3 ± 3.1 mL/kg/min; HIIT₁₁₅: +3.3 ± 3.6 ml/kg/min; Time effect P = 0.002; Group effect: P = 0.95), P_peak (HIIT₈₅: +18 ± 9 W; HIIT₁₁₅: +16 ± 27 W; Time effect P = 0.045; Group effect: P = 0.49), and mean anaerobic power (HIIT₈₅: +0.42 ± 0.69 W/kg; HIIT₁₁₅: +0.55 ± 0.65 W/kg; Time effect P = 0.01; Group effect: P = 0.18). Six weeks of submaximal and supramaximal interval training performed to exhaustion seems to equally improve VO_2max and anaerobic power in endurance‐trained men, despite half the accumulated time spent at the target intensity.     

Intermittent hypoxia improves endurance performance and submaximal exercise efficiency

The purpose of the present study was to elucidate the influence of intermittent hypobaric hypoxia at rest on endurance performance and cardiorespiratory and hematological adaptations in trained endurance athletes. Twelve trained male endurance runners were assigned to either a hypoxic group (n = 6) or a control group (n = 6). The subjects in the hypoxic group were exposed to a simulated altitude of 4500 m for 90 min, three times a week for 3 weeks. The measurements of 3000 m running time, running time to exhaustion, and cardiorespiratory parameters during maximal exercise test and resting hematological status were performed before (Pre) and after 3 weeks of intermittent hypoxic exposure (Post). These measurements were repeated after the cessation of intermittent hypoxia for 3 weeks (Re). In the control group, the same parameters were determined at Pre, Post, and Re for the subjects not exposed to intermittent hypoxia. The athletes in both groups continued their normal training together at sea level throughout the experiment. In the hypoxic group, the 3000 m running time and running time to exhaustion during maximal exercise test improved. Neither cardiorespiratory parameters to maximal exercise nor resting hematological parameters were changed in either group at Post, whereas oxygen uptake (.V(O2)) during submaximal exercise decreased significantly in the hypoxic group. After cessation of intermittent hypoxia for 3 weeks, the improved 3000 m running time and running time to exhaustion tended to decline, and the decreased .V(O2) during submaximal exercise returned to Pre level. These results suggest that intermittent hypoxia at rest could improve endurance performance and submaximal exercise efficiency at sea level in trained endurance athletes, but these improvements are not maintained after the cessation of intermittent hypoxia for 3 weeks.     

Effects of preexercise feedings on endurance performance

Eight male and female students were studied during exercise to exhaustion on a bicycle ergometer at 80 and 100% of Vo2max following the ingestion of water (W), 75 g of glucose (G) or a liquid meal (M) (10 g protein, 12.5 g fat, 15 g CHO). When compared to the endurance ride (80% Vo2max) in the W treatment, endurance performance time was reduced by 19%, (p less than .05) (53.2 to 43.2 min) as a result of the preexercise glucose feeding (Trial G). No difference in performance at 80% Vo2max was found between the W and M trials. The preexercise feedings had no effect on exercise time to exhaustion at 100% Vo2max. During the G and M trials at 80% Vo2max, most of the subjects demonstrated a transient decline in serum glucose (less than 3.5 mM). After 30-40 min. of exercise, however, serum glucose returned to normal and was seldom low at the time of exhaustion. Serum free fatty acids (FFA) were depressed throughout the G trial. The results of these experiments indicate impaired lipid mobilization following CHO ingestion. The present data support our earlier findings (11) which demonstrate that glucose feedings 30-45 minutes before endurance exercise increase the rate of CHO oxidation and impede the mobilization of FFA, thereby reducing exercise time to exhaustion.     

Effects of music tempo upon submaximal cycling performance

In an in vivo laboratory controlled study, 12 healthy male students cycled at self‐chosen work‐rates while listening to a program of six popular music tracks of different tempi. The program lasted about 25 min and was performed on three occasions – unknown to the participants, its tempo was normal, increased by 10% or decreased by 10%. Work done, distance covered and cadence were measured at the end of each track, as were heart rate and subjective measures of exertion, thermal comfort and how much the music was liked. Speeding up the music program increased distance covered/unit time, power and pedal cadence by 2.1%, 3.5% and 0.7%, respectively; slowing the program produced falls of 3.8%, 9.8% and 5.9%. Average heart rate changes were +0.1% (faster program) and ?2.2% (slower program). Perceived exertion and how much the music was liked increased (faster program) by 2.4% and 1.3%, respectively, and decreased (slower program) by 3.6% and 35.4%. That is, healthy individuals performing submaximal exercise not only worked harder with faster music but also chose to do so and enjoyed the music more when it was played at a faster tempo. Implications of these findings for improving training regimens are discussed.     

Effects of acute ingestion of salbutamol during submaximal exercise

To assess the eventual effects of acute oral salbutamol intake on performance and metabolism during submaximal exercise, nine healthy volunteers completed two cycling trials at a power corresponding to 80-85% VO2max, after either placebo (Pla) or salbutamol (Sal, 6 mg) treatment, according to a double-blind randomized protocol. Blood samples were collected both at rest and during exercise (5 min-, 10 min-, 15 min-exhaustion) for C-peptide, FFA, lactate and blood glucose measurements. Cycling performance was significantly improved in the Sal vs. Pla trials (p < 0.05). After Sal intake, resting C-peptide, lactate, FFA and blood glucose values were higher whereas exercise lactate and free fatty acid concentrations were greater during and at the conclusion of the exercise period (p < 0.05). These results suggest that acute salbutamol ingestion improved performance during submaximal exercise probably through an enhancement of the overall contribution to energy production from both aerobic and anaerobic metabolisms.     

Effects of acute prednisolone intake on substrate utilization during submaximal exercise

We examined the hypothesis that acute therapeutic glucocorticoid intake could change the contribution of fat and carbohydrate (CHO) in energy production during exercise. Nine healthy recreationally-trained male subjects twice performed submaximal exercise (60 min at 60 % VO2max) after ingestion of placebo (Pla) or 20 mg of prednisolone (Pred), according to a double blind and randomized protocol. Respiratory exchange was monitored during exercise and blood samples were collected at rest, every 10 min during exercise and after 5, 10, and 20 min of passive recovery. Pred intake significantly increased total energy expenditure during exercise, but CHO oxidation was lower and fat oxidation higher after Pred vs. Pla. ACTH and IL-6 concentrations were significantly decreased with Pred during exercise, whereas no variations were found in GH, insulin, blood glucose, and lactate between the 2 treatments. In conclusion, it appears that acute prednisolone systemic administration does reduce total carbohydrate oxidation during submaximal exercise. Further studies are necessary to clarify the mechanisms involved and to determine whether this modification in the substrate oxidation balance under glucocorticoid administration in recreationally-trained male subjects could result in a competitive advantage in elite athletes.     

Effects of respiratory muscle endurance training on ventilatory and endurance performance of moderately trained cyclists

This study examined the effects of respiratory muscle endurance training (RMET) on ventilatory and endurance performance among moderately trained, male cyclists. Nine subjects initially completed two cycling VO2 max tests, two endurance cycling tests for time at 95% VO2 max, a 15-s MVV test, and an endurance breathing test for time at 100% MVV. Four subjects then underwent 3 weeks of strenuous RMET while five served as controls. Mean posttest 15-s MVV and endurance breathing time were significantly higher in the RMET group (243 +/- 14 l X min-1 and 804 +/- 94 s) than in the control group (205 +/- 6 l X min-1 and 48 +/- 8 s). No significant group differences in VO2 max or endurance cycling time at 95% VO2 max were observed following RMET. Results of this exploratory study indicated that RMET improved ventilatory power and endurance, but did not alter VO2 max or endurance cycling performance among moderately trained, male cyclists.     

Effects of acute prednisolone intake during intense submaximal exercise

To study the effects of a therapeutical dose of corticosteroid alone or associated with beta-2 agonist on performance and substrate response during intense submaximal exercise, seven healthy moderately trained male volunteers participated in the double-blind randomized cross-over study. An intense endurance exercise test to exhaustion was performed after ingestion of placebo (Pla), 20 mg prednisolone (Pred), and 20 mg prednisolone plus 4 mg salbutamol (Pred-Sal). Blood samples were collected at rest, after 5, 10 min of exercise, at exhaustion, and after 5 (r5), 10 (r10), and 20 (r20) min of passive recovery for ACTH, growth hormone, insulin, blood glucose, and lactate measurements. There were no significant differences in exercise time to exhaustion between the three treatments (Pla: 21.5 +/- 2.9; Pred: 22.0 +/- 2.5; Pred-Sal: 24.2 +/- 2.8 min). ACTH was significantly lowered after Pred and Pred-Sal vs. Pla from the start of exercise to the end of the experiment (p < 0.05). Pred and Pred-Sal increased resting and recovery (r10 and r20) significantly but not exercise blood glucose values. There were no significant differences in growth hormone concentrations between the three treatments whereas insulin was significantly higher at rest, during exercise, and at r20 after Pred-Sal administration vs. Pred and Pla (p < 0.05). Pred and Pred-Sal showed no significant effect on blood lactate compared with Pla treatment. These preliminary results do not support the hypothesis that acute oral therapeutic corticosteroid intake alone or associated with beta-2 mimetic improves performance during intense submaximal exercise, but further studies are necessary with tests of longer duration.     

Effects of submaximal cycling and long-term endurance training on neutrophil phagocytic activity in middle aged men.

OBJECTIVE: To investigate the effects of long term (> 10 years) endurance training and submaximal exercise on the phagocytic activity of circulating neutrophil granulocytes. METHODS: The ability of stimulated blood neutrophils isolated from well trained cyclists [n = 8; VO2max 61.0(SD 8.8) ml.kg-1.min-1; age 38(4) years] and age matched sedentary controls [n = 8; VO2max 37.4 (6.6) ml.kg-1.min-1] to ingest nitroblue tetrazolium was assessed at rest and following a standardised submaximal bout of exercise on a cycle ergometer. RESULTS: Trained subjects had a lower resting blood neutrophil count (P < 0.01). Acute exercise caused a rise (P < 0.01) in the blood neutrophil count irrespective of training status, but the magnitude of the rise was smaller in the trained subjects (P < 0.05). The circulating neutrophil phagocytic capacity was approximately 70% lower in trained individuals at rest compared with the control subjects (P < 0.01). Acute submaximal exercise increased this variable in both groups, but phagocytic capacity remained substantially lower in the trained subjects compared with the controls (P < 0.05) despite the observation that a higher proportion of the circulating neutrophils were stimulated to undergo phagocytosis in the trained subjects [57(14)% v 32(7)%; P < 0.01). CONCLUSIONS: Although neutrophil phagocytic activity is only one variable that contributes to immunological status, prolonged periods of endurance training may lead to increased susceptibility to opportunistic infections by diminishing this activity at rest.     

Effects of strength training on lactate threshold and endurance performance

To determine the effects of 12 wk of strength training on lactate threshold (LT) and endurance performance, 18 healthy untrained males between 25 and 34 yr of age were randomly assigned to either strength training (N = 10) or control (N = 8) groups. Despite no changes in treadmill VO2max or cycle peak VO2, a 33 +/- 5% increase (P less than 0.001) in cycling time to exhaustion at 75% of peak VO2 was observed following training. No significant changes in cycling time were observed in the control group. There were significant reductions in plasma lactate concentration at all relative exercise intensities ranging between 55 and 75% of peak VO2 training. The improved endurance performance was associated with a 12% increase in LT (r = 0.78, P less than 0.001). The strength training program resulted in significant improvements (P less than 0.001) of 31 +/- 5% and 35 +/- 7% in isokinetic peak torque values for leg extension and flexion, respectively, at a velocity of 30 degrees.s-1. There were also significant increases in 1-RM values of 30 +/- 4% (P less than 0.001) for leg extension, 52 +/- 6% (P less than 0.001) for leg flexion, and 20 +/- 4% (P less than 0.001) for the bench press. These findings indicate that strength training improves cycle endurance performance independently of changes in VO2max. This improved performance appears to be related to increases in LT and leg strength.     

Repeated exposure to moderate cold impairs matching-to-sample performance

To study effects of moderate cold (5 degrees C) on complex cognitive performance, subjects were exposed to cold while responding on a conditional discrimination task. The task required a correct choice of which of two simultaneously presented matrices matched a previously presented sample matrix. The effects of task performance in cold and ambient temperatures was examined on three repeated occasions, one pair of conditions per week. Responses accuracy was consistently impaired in each cold session. In addition, choice response latencies lengthened and sample response latencies decreased in all cold exposures. The data show that even moderate cold exposure that does not produce core hypothermia can impair performance of a complex cognitive task and that the magnitude of performance change is not attenuated by a brief series of cold exposures.     

急性冷暴露对大鼠血脑屏障通透性的影响及木樨草素的保护作用

目的:对大鼠进行急性冷暴露,探讨冷暴露对大鼠血脑屏障(BBB)通透性的影响及木樨草素对大脑保护的可能性。方法:建立大鼠冷暴露模型,用比色法测定脑组织中伊文思兰(EB)含量关系及干-湿重法检测脑组织含水量变化,反映大鼠BBB通透性的影响。结果:冷暴露后大鼠脑组织水分含量和伊文思兰明显增高,BBB通透性明显增加,添加木樨草素的防护组则通透性受到不同程度的改变。结论:脑组织在冷暴露下BBB通透性增高,木樨草素有一定的保护作用。     

Effects of warm-up and precooling on endurance performance in the heat

Objective

To examine the effects of different thermoregulatory preparation procedures (warm‐up (WU), precooling (PC), control (C)) on endurance performance in the heat.

Methods

20 male subjects completed three treadmill runs to exhaustion (5 days apart). In each session, all subjects performed an incremental running test after WU (20 min at 70% maximum heart rate (HR)), after PC (wearing a cooling vest (0°C–5°C) for 20 min at rest) or without particular preparation (C). After a 5‐min break, the exercise protocol commenced at a workload of 9 km/h and was increased by 1 km/h every 5 min until the point of volitional fatigue. Running performance, HR, blood lactate concentration, tympanic temperature and skin temperature were measured in each trial.

Results

In the PC condition, the running performance (32.5 (5.1) min; mean (SD)) was significantly (p<0.05) higher than in WU (26.9 (4.6) min) and in C conditions (30.3 (4.3) min). During the first 30 min of testing, HR, tympanic temperature and skin temperature were significantly (p<0.05) lower after PC than after WU. There were no significant differences in lactate concentration; however, there was a trend to lower values after WU.

Conclusions

The use of an ice‐cooling vest for 20 min before exercising improved running performance, whereas the 20 min WU procedure had a distinctly detrimental effect. Cooling procedures including additional parts of the body such as the head and the neck might further enhance the effectiveness of PC measures.It is well established that high ambient temperatures have a detrimental effect on endurance performance.^1,2 Compared with temperate conditions (20°C), an ambient temperature of 30°C brought about a decrease of 2.3% in the performance of a 10 min exercise bout.² The question, however, as to what strategies could be applied to compensate for this heat‐induced decrease in performance has been left largely unanswered. Sufficient fluid intake is a possible answer, and application of cold provides another one.^3,4 In the context of endurance in heat a further question arises—namely, whether warm‐up (WU; including the concomitant increase in core temperature (CT)) is a sensible measure, taking into consideration the additional thermal stress.⁵For this reason, it is useful to compare the effects of WU and precooling (PC) to optimise endurance performance. The practical relevance of the objective lies in the fact that competitions—for example, the Olympic Games 2008 in Beijing—will be held in high ambient temperatures, exceeding 30°C at all times of day, and there is no coherent (systematically and experimentally tested) position in the literature on the implications of WU^6,7 for endurance performance in such temperatures. Although PC has been discussed more widely during the last two decades,^8,9,10 it has not yet been studied in comparison with active WU.     

The acute effects of two energy drinks on endurance performance in female athlete students

Energy drinks have gained popularity among athletes. The purpose of this study was to determine the acute effects of Phantom and Dragon energy drinks on endurance performance. For this reason 12 female athlete students of Tehran University (age 22±0.63 years, height 162.1±5.8 cm, weight 56.91±6.79 kg) volunteered and performed three sessions on a Bruce treadmill test four days apart from each other. In each session, in a randomised, placebo-controlled, counterbalanced and double-blind design 6 ml/kg body weight of Phantom, Dragon or placebo was consumed 40 min before an exercise test. Using a 3×3 repeated measures analysis of variance and Least Significant Difference (LSD), a significant increase in VO₂max time to exhaustion and a decrease in post-test rating of perceived exertion was found for Phantom and Dragon vs. placebo (p<0.05). No significant difference was observed in pre-test hear rate for three drinks (p>0.05). Post-test hear rate increased significantly for Dragon vs. Phantom and placebo (p<0.05). In conclusion, two commercially available energy drinks had ergogenic effects on endurance performance.     

The influence of training on endurance and blood lactate concentration during submaximal exercise.

The purpose of this study was to examine the effect of short-term training on maximum oxygen uptake (VO2 max) and two different measures of endurance performance. Endurance was determined for 15 female subjects (7 training, 8 control) as (1) exercise time to exhaustion at 80% VO2 max (T80%) and (2) the highest relative exercise intensity tolerable during a 30-minute test (T30 min), before and after a 6-week training period. In addition, VO2 max and the work rate equivalent to a blood lactate concentration of 4 mmol.l-1 (OBLA) were determined. Maximum oxygen uptake increased by 24% (p less than 0.01) for the training group (TG) and 7% (p less than 0.01) for the control group (CG). Cumulative average work rate (CAWR) during T30 min increased by 25% for the TG while there was no change for the CG. No significant difference was found pre- and post-training in the %VO2 max (estimated from CAWR) at which the TG and CG performed T30 min. Exercise time to exhaustion on T80% increased by 347% (p less than 0.01) and 16% (NS) for the TG and the CG respectively. Good correlations were found between VO2 max and CAWR (W) (pre-training r = 0.84; post-training r = 0.83), OBLA (W) and CAWR (W) (pre-training r = 0.89; post-training r = 0.88) and change in endurance time and the change in submaximal blood lactate concentration (r = 0.70, p less than 0.01). The results of this study suggest that the ability to sustain a high relative exercise intensity is not enhanced following short-term training.