He-Ne 激光血管内照射对脑梗死患者的影响

目的探讨He-Ne激光血管内照射对脑梗死患者的疗效及对血液流变性质的影响. 方法对42例脑梗死随机分成两组. 对照组采用常规药物治疗,治疗组在常规药物治疗的基础上加用He-Ne激光血管内照射治疗,观察两组血液流变学指标及疗效. 结果治疗组有效率85%,对照组有效率61. 9%. 治疗组全血粘度(低切、高切) 、毛细血管血浆粘度、血沉、血沉方程K值、红细胞聚集指数、红细胞刚性指数较前明显下降,红细胞变形指数较治疗前增加(p<0.05). 结论激光血管内照射能有效改善血液流变学性质,改善微循环,增加脑血流量,促进神经功能的恢复,显著提高脑梗死患者的疗效.     

半导体绿激光血管内照射治疗老年期痴呆的临床研究

探索半导体绿激光血管内照射治疗血管性痴呆、阿尔茨海默病的临床效果。对住院６例血管性痴呆、４例阿尔茨海默病患者进行绿激光血管内照射治疗,在治疗前后分别做血液流变学,神经心理测验以及ＴＣＤ、ＥＥＧ、ＥＫＧ等实验室检查比较。治疗后血液流变学指标明显下降,神经心理测验有改善趋势。半导体绿激光血管内照射疗法可改善血管性痴呆、阿尔茨海默病患者的血液流变学指标和改善临床症状。     

He—Ne激光血管内照射对脑梗死患者的影响

目的　探讨He-Ne激光血管内照射对脑梗死患者的疗效及对血液流变性质的影响 .方法　对 4 2例脑梗死随机分成两组 .对照组采用常规药物治疗 ,治疗组在常规药物治疗的基础上加用He-Ne激光血管内照射治疗 ,观察两组血液流变学指标及疗效 .结果　治疗组有效率 85 % ,对照组有效率 6 1.9% .治疗组全血粘度 (低切、高切 )、毛细血管血浆粘度、血沉、血沉方程K值、红细胞聚集指数、红细胞刚性指数较前明显下降 ,红细胞变形指数较治疗前增加 (p<0 .0 5 ) .结论　激光血管内照射能有效改善血液流变学性质 ,改善微循环 ,增加脑血流量 ,促进神经功能的恢复 ,显著提高脑梗死患者的疗效     

半导体激光体外照射血管治疗仪的研制

为克服 He-Ne激光血管内照射疗法所具有的不足,我们采用830nm、500mW半导体激光器,研制了用于体外血管照射的激光治疗仪.设计了易于固定的激光输出头,并且采用单片机控制整机,提高了仪器的稳定性和可靠性.临床应用取得了令人满意的治疗效果.     

静脉溶栓桥接支架取栓治疗对急性脑梗死患者神经功能和血管再通率的影响分析

目的分析静脉溶栓桥接支架取栓治疗对急性脑梗死患者神经功能和血管再通率的影响。方法选取本院2016年12月～2019年12月收治的120例急性脑梗死患者作为研究对象,根据治疗方法的不同将其分为观察组(采用静脉溶栓桥接支架取栓治疗)和对照组(采用rt-PA静脉溶栓治疗),每组各60例。比较两组患者治疗后血管再通率、神经功能恶化率、100d后病死率以及治疗后(24h、15d、20d)神经功能情况。结果观察组患者治疗后血管再通率为71.66%,明显高于对照组(35.00%)(P0.05);两组患者神经功能恶化率和100d后病死率比较,差异无统计学意义(P0.05);治疗后24h两组患者NIHSS评分比较无差异(P0.05),治疗15d、20d后两组患者NIHSS评分明显下降,且观察组患者NIHSS评分下降程度比对照组更明显(P0.05)。结论静脉溶栓桥接支架取栓治疗可提高急性脑梗死患者血管再通率,有效改善患者神经功能,临床效果好。     

低能量He—Ne激光血管内照射对缺血性心脑血管病血液流变学的影响

低能量He－Ne激光血管内照射（ILIB）疗法近年在临床逐步推广应用。本文报道应用ILIB治疗100例缺血性心脑血管病患者，其对血液粘度等指标及临床症状和体征均有良好的改善作用。资料与方法1、观察对象本文病例均系1994年1月一95年12月内科住院患者。其中男66例，女34例，年龄41～82岁，平均69岁。病种为脑血栓形成29例，脑动脉硬化及脑供血不足27例，冠心病心绞痛36例，心肌梗塞8例。2、ILIB治疗使用HE－IO（）I型氧氖激光血管内治疗仪。经静脉留置针穿刺，将激光外导入上肢肘正中静脉或贵要静脉。激光输出功率为1．5～2．omw。每天…     

半导体绿激光血管内照射治疗老年期痴呆的临床观察

目的 探索半导体绿激光血管内照射治疗血管性痴呆、阿尔茨海默病的临床效果。方法 对住院17例血管性痴呆、13例阿尔茨海默病患者进行绿激光血管内照射治疗。在治疗前后分别做血流流变学、神经心理测验以及TCD、EEG、EKG等实验室检查比较。结果 治疗后全血粘度、血浆粘度、红细胞聚集指数等血液流学学指标明显下降（P＜0．01），神经心理测验MMSE、ADL、HDS等均有明显改善（P＜0．01）。结论 半导体激光血管内照射疗法可改善血管性痴呆、阿尔茨海默病患者的血流流学变指标和改善临床症状。     

激光血管内照射疗法对海洛因戒断综合征的疗效观察

本文采用低强度激光血管内照射疗法对30例吸毒者的戒断综合征患者予以治疗,并与对照组比较。结果证明:该疗法在治疗过程中其效果明显优于对照组(P<0.01),值得推广。     

抗生素序贯疗法对儿童急性呼吸道感染的临床观察

目的探讨序贯疗法对小儿急性呼吸道感染的治疗效果.方法将130例急性呼吸道感染患儿随机分为观察组和对照组,观察组62例采用抗生素序贯疗法:胃肠道外抗生素治疗2～3d(静脉滴注或肌肉注射)改用胃肠道给药2～5d,总疗程4～8d.对照组68例采用胃肠道外静脉给药直至体温正常,全身症状明显改善,总疗程5～11d.结果两组治愈率相同,观察组住院时间住院费用明显少于对照组.结论抗生素序贯疗法治疗小儿急性呼吸道感染疗程短、经济、方便值得推广.     

抗生素序贯疗法对儿童急性呼吸道感染的临床观察

目的　探讨序贯疗法对小儿急性呼吸道感染的治疗效果 .方法　将 130例急性呼吸道感染患儿随机分为观察组和对照组 ,观察组 6 2例采用抗生素序贯疗法 :胃肠道外抗生素治疗 2～ 3d(静脉滴注或肌肉注射 )改用胃肠道给药 2～ 5d ,总疗程 4～ 8d .对照组 6 8例采用胃肠道外静脉给药直至体温正常 ,全身症状明显改善 ,总疗程 5～ 11d .结果　两组治愈率相同 ,观察组住院时间住院费用明显少于对照组 .结论　抗生素序贯疗法治疗小儿急性呼吸道感染疗程短、经济、方便值得推广     

动脉硬化性脑梗死患者血脂和血液流变性特征及元活苏合用曲克芦丁的疗效观察

目的:探讨动脉硬化性脑梗死患者血液流变学和血脂指标异常特征及脑蛋白水解物(元活苏)合用曲克芦丁对其的治疗作用。方法:69例动脉硬化性脑梗死患者随机分为合并治疗组35例和丹参治疗对照组34例。30名健康老年人作正常对照。比较治疗前后各组病人血液流变性及血脂变化。结果:合并治疗组总有效率(94.29%)优于丹参对照组(73.52%)(P<0.05);两组治疗前血液流变学和血脂指标均高于正常组(P<0.01),治疗后均有显著改善(P<0.01);合并治疗组降脂降粘效果明显优于丹参对照组(P<0.05)。结论:动脉硬化性脑梗死患者的血液流变性及血脂明显异常,元活苏合并曲克芦丁治疗动脉硬化性脑梗死疗效显著。     

Increased neutrophil-to-lymphocyte ratio predicts persistent coronary no-flow after wire insertion in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

OBJECTIVES:

Acute ST-segment elevation myocardial infarction patients presenting persistent no-flow after wire insertion have a lower survival rate despite successful mechanical intervention. The neutrophil-to-lymphocyte ratio has been associated with increased mortality and worse clinical outcomes in ST-segment elevation myocardial infarction. We hypothesized that an elevated neutrophil-to-lymphocyte ratio would also be associated with a persistent Thrombolysis In Myocardial Infarction flow grade of 0 after wire insertion in patients undergoing primary percutaneous coronary intervention.

METHODS:

A total of 644 patients with ST-segment elevation myocardial infarction who underwent primary percutaneous coronary intervention within 12 hours of symptom onset were included in our study. Blood samples were drawn immediately upon hospital admission. The patients were divided into 3 groups according to their Thrombolysis In Myocardial Infarction flow grade: Thrombolysis In Myocardial Infarction flow grade 0 after wire insertion, Thrombolysis In Myocardial Infarction flow grade 1-3 after wire insertion and Thrombolysis In Myocardial Infarction flow grade 1-3 at baseline.

RESULTS:

The neutrophil-to-lymphocyte ratio was significantly higher in the group with Thrombolysis In Myocardial Infarction flow grade 0 after wire insertion compared with the group with Thrombolysis In Myocardial Infarction flow grade 1-3 after wire insertion and the group with Thrombolysis In Myocardial Infarction flow grade 1-3 at baseline. The group with Thrombolysis In Myocardial Infarction flow grade 0 after wire insertion also had a significantly higher in-hospital mortality rate. Persistent coronary no-flow after wire insertion was independently associated with the neutrophil-to-lymphocyte ratio.

CONCLUSIONS:

An increased neutrophil-to-lymphocyte ratio on admission is significantly associated with persistent coronary no-flow after wire insertion in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.     

强脉冲光联合Nd:YAG激光治疗黄褐斑疗效观察

目的:探讨强脉冲光联合Nd:YAG激光治疗黄褐斑的疗效。方法:60例患者按治疗方法不同分成3组:强脉冲光组、Nd:YAG激光组、联合组（强脉冲光联合Nd:YAG激光组）,每组20例患者,观察3组患者疗效和副作用。结果:3组之间疗效两两比较采用Mann-Whitney秩和检验,强脉冲光组和激光组疗效无显著差异,而联合组疗效显著好于强脉冲光组（Z=7.123, P=0.024）和激光组（Z=6.024, P=0.030）。3组患者治疗后均无出现色素沉着加重、色素脱失病等不良反应。强脉冲光组和激光组的满意度无显著差异,而联合组的满意度显著好于强脉冲光组（Z=7.361, P=0.029）和激光组（Z=6.831, P=0.027）。结论:强脉冲光联合Nd:YAG激光治疗黄褐斑是一种安全有效的治疗方法,值得临床推广。     

高压氧联合药物治疗少、弱精子症的临床观察

目的探讨高压氧联合药物治疗少弱精子症的治疗效果。方法少弱精子症患者90例,随机分为3组,每组30例。药物组口服己酮可可碱、维生素AD油丸等,高压氧(HBO)组施行HBO治疗。联合组在口服药物的同时施行HBO治疗。治疗前及结束后1周分别进行精子化验,治疗后6个月随访患者配偶妊娠情况。结果药物组和HBO组的临床治愈率、总有效率相近(χ2=0.24、0.07,P>0.05)。联合组的临床治愈率、总有效率高于其他两组(χ2=6.39、13.05,P<0.05、0.01)。结论高压氧联合药物治疗可明显提高少弱精子症患者的生育能力,临床效果优于单纯药物或高压氧治疗。高压氧可作为治疗少弱精子症的有效措施之一。     

激光光凝手术治疗眼底疾病的临床效果研究

目的观察应用激光光凝手术治疗眼底疾病的临床疗效和并发症情况,评价其临床应用价值遥方法选择我院2014 年5 月~2016 年1 月收治的100 例眼底疾病患者,根据治疗方式分成两组,对照组50 例患者选择临床常规治疗,实验组50 例患者 选择激光光凝手术治疗,分析两组患者的临床疗效和并发症发生情况遥结果实验组的临床治疗总有效率显著高于对照组,两 者比较差异有统计学意义（约0.05）曰实验组的并发症发生率显著低于对照组,两者比较差异有统计学意义（约0.05）遥结论在 对眼底疾病患者进行治疗时,激光光凝手术治疗能提高临床疗效,降低并发症发生率,具有临床应用价值遥     

Does low output laser stimulation enhance the healing of crural ulceration? Some critical remarks

The objective of the experiment was to evaluate the impact of laser stimulation on crural ulceration healing.Three groups were established at random from patients with crural ulceration: A, B and C. Group A included 21 patients, group B included 22 patients and group C, 22 patients. Patients in all groups were treated with pharmaceuticals and with compressive therapy. The ulcers in group A were additionally irradiated with laser light of wavelength 810 nm, so that a dose of 4 J/cm2 was applied in each procedure. Patients in group B were additionally subjected to a blind test (with placebo in the form of quasi-laser therapy).At the end of the treatment a statistically significant reduction of the area and volume of the ulcers was found in all groups. No statistically significant difference was found between the groups in terms of average rate of change per week of the relative area of ulceration and average rate of change per week of the relative volume of ulceration. Reduction of infected area was observed in all groups, but a significant change was only observed in group C.No significant impact of laser light (lambda=810 nm, P=65 mW, p=4 J/cm2) on any of the stages of ulceration healing was observed.     

CO2激光与药物联合治疗瘢痕疙瘩—附30例疗效及随访观察

目的：观察CO2激光与药物联合治疗瘢痕疙瘩的临床疗效。材料与方法：CO2激光烧灼至瘢痕完全去除，以不损伤脂肪层为宜，待创面基底部形成纤维组织时，在创缘及基底部注射由皮皮激素为主配制的混悬液，每7－10天一次，共4－5次。对照组为冷冻和手术切除后按上述方法注射相同药物。结果：经一年随访，治疗组有效率95．83％，与对照组冷冻78．26％和手术80．43％对比，差异有显著性意义（P＜0．05）。结论：CO2激光联合药物治疗瘢痕疙瘩是一种简单有效的方法。     

DNR versus DNT: clinical implications of a conceptual ambiguity: a case analysis

Psychiatrists who practice psychosomatic medicine are routinely called upon to help resolve ethical dilemmas that arise in the care of patients near the end of their lives. Psychosomatic-medicine psychiatrists may be of unique value in these situations because of the clinical insights that we bring to the care of the dying patient. In particular, our subspecialty brings expertise related to the evaluation of decisional capacity of patients who are faced with accepting or declining end-of-life clinical interventions, such as resuscitation and intubation. In this first entry in a new bioethics case series in Psychosomatics, we will lay the groundwork for examining a complex patient case and provide an illustrative analysis of the end-of-life care issues that may be addressed by psychiatrists who practice psychosomatic medicine.     

综合康复干预对全髋置换后早期并发症的预防作用

背景:全髋关节置换后并发症发生率仍较高,置换后早期功能恢复能有效保证置换效果。 目的:评价综合康复干预在预防全髋关节置换后早期并发症中的作用。 方法:将90例全髋关节置换患者随机分为对照组和试验组,两组行全髋关节置换后均给予常规治疗、干预,其中试验组置换后给予综合康复干预,而对照组给予一般程序化康复干预。 结果与结论:两组患者在置换后1,2,12和20周Harris评分差异无显著性意义(P > 0.05);试验组置换后2,12周关节脱位、感染、下肢深静脉血栓形成的发生率及置换后12周异位骨化的发生率均显著低于对照组(P < 0.01)。提示综合康复干预可明显减少全髋关节置换后早期并发症,有效促进髋关节的功能恢复。     

比较5种不同盖髓剂长期护髓的差异

背景：在深龋治疗中,采用盖髓剂间接盖髓,可诱导牙髓牙本质复合体形成牙本质桥,保护牙髓组织免受刺激,保存活髓,彻底避免并发症的出现,临床成功率较高。 目的：对比5种不同氢氧化钙制剂间接盖髓的临床效果差异。 方法：纳入236例深龋患者,随机分组,分别采用双组分氢氧化钙粉剂(n=46)、单组分注射剂型化学固化氢氧化钙制剂Metapex(n=47)、化学固化型氢氧化钙制剂Dycal(n=45)、单组分光固化氢氧化钙制剂Ionosit-Baseliner(n=49)及单组分光固化氢氧化钙制剂Calcimol LC(n=49)间接盖髓,盖髓后第1,6,12,24个月随访,观察牙髓状况、充填体是否脱落及根尖状况等。 结果与结论：随访1,6,12个月,5组间盖髓成功率比较差异无显著性意义(P > 0.05);随访24个月时,双组分氢氧化钙粉剂组盖髓成功率低于其他4组(P < 0.05),后4组间盖髓成功率比较差异无显著性意义(P > 0.05)。表明氢氧化钙制剂Metapex、Dycal、Ionosit-Baseliner及Calcimol LC对深龋治疗均具有良好的盖髓效果,可长期护髓。中国组织工程研究杂志出版内容重点：生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程全文链接：