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《中医杂志(英文版)》2014,34(5):584-590
ObjectiveThe purpose of this study was to evaluate the antioxidant activity, phenolic and flavonoids contents of selected medicinal plants form the Western region of Nepal.MethodsThe antioxidant activity of selected medicinal plants were determined by using 2, 2-diphenyl-1-picrylhydrazyl radical scavenging activity; total ferric ion reducing ability through spectroscopic analysis. The content of total phenols was determined using Folin-Ciocalteu reagent, whereas Aluminum chloride colorimetric method was used for flavonoid determination.ResultsExtracts of Syzygium Operculatus (87%), Astilbe Rivularis (83%) and Mallotus Philippnensis (88%) showed significant free radical scavenging activity with effective concentration (EC50) close to that of ascorbic acid. Syzygium Operculatus (96%), Astilbe Rivularis (97%) and Mallotus Philippnensis (97%) had potent reducing power in concentration dependent fashion. Those plant extract with higher free radical scavenging and ferric reducing effect also showed the greater content of both phenols and flavonoids, suggesting the correlation between polyphenolic content and antioxidant activity. Those plant extracts which showed better antioxidant activity assays, also demonstrated higher total phenol and flavonoid contents. These three plants showed the presence of higher amount of phenols and flavonoids.ConclusionThis study may provide the scientific basis for the traditional use of those plants and may provide valuable idea for further research. 相似文献
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本文报告电子计算机在花类药材检索中的应用.作者以花类药材的19个性状特征为指标,观察41种药材,将其特征进行编码后输入计算机,建立标准药材数据库.用BASIC语言编制了标准品判别指数的程序和待检药材检索程序,利用计算机将待检品的编码信息与数据库中标准药材的编码信息逐一进行比较,就能简单、迅速、准确地检索出和待检药材完全相同或相似的标准药材,同时指出与标准药材特征不同的编码信息序号、释疑信号,以便核对时参考. 相似文献
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全草类中药材中的粉螨孳生情况调查 总被引:1,自引:0,他引:1
目的 调查全草类中药材粉螨孳生情况。方法 用清水漂浮法和塔氏电热集螨器分离全草类中草药中粉螨。结果 从58种580份全草类中药材样本中共分离出32种粉螨,录属6科24属,检出率达100%,其中两种以上粉螨(含两种)污染的该类中药材达35种,占60.3%。结论 全草类中药材中粉螨慈生严重,在该类中药材保储时应注意防螨。 相似文献
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海南野生野牡丹科药用观赏植物资源的调查 总被引:1,自引:0,他引:1
目的:研究海南产野生野牡丹科药用观赏植物的开发利用情况。方法:实地调查和文献查证相结合研究中药、黎药和苗药中野牡丹科植物的种类、应用价值和其观赏价值。结果:海南产野生野牡丹科植物有14种可作为中药的来源,初步查明黎药和苗药来源中各有1种野牡丹科植物,具有较高的药用价值和观赏价值,并在上述结果的基础上提出了开发利用措施及建议。结论:通过发挥药用观赏植物的优势,可以为城市建设和药材生产服务,提高资源的利用水平。 相似文献
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目的 探讨中西医结合治疗糖尿病足的临床疗效观察.方法 收治我院2008 年1 月-2010 年10 月收治的74 例糖尿病足患者,对照组应用西医常规用药治疗,治疗组在对照组的基础上加中药治疗.比较两组治疗临床疗效,及血糖、血脂、纤维蛋白原及踝肱指数(ABI).结果 对照组治愈率为52.9%,总有效率为91.2%.治疗组治疗率为85.0%,总有效率为97.5%.两组比较总体疗效治疗组优于对照组,P 〈0.05;总胆固醇、甘油三脂及纤维蛋白原比较,差异有统计学意义(P 〈0.05).两组治疗后ABI指数有显著改善(P 〈0.05).结论 中西医结合治疗糖尿病足(DF),可以提高临床有效率,改善血脂血糖水平及踝肱指数的疗效较单用西医药治疗为好. 相似文献
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根据作者多年的研究经历及近年来国内外的研究进展,结合我国中医药的优势,从现代生物技术的产生与广泛应用、中药有效成分及药材质量控制研究的重要性出发,系统地阐述了现代生物技术应用于药用植物研究的重要性及其发展趋势。着重从药用植物无性繁殖系的建立与快速繁殖、细胞次生代谢调控、药材质量标准体系的构建等方面,详细介绍了药用植物生物技术及药材质量标准研究的具体方法,以期为实现中药的安全、有效、稳定、可控和中药走向世界提供参考。 相似文献
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Dai Guohua Gao Wulin Bi Dongxue Liu Chunhua Liu Yuhan Wang Ning Zhao Chen 《中医杂志(英文版)》2018,38(3):412-418
OBJECTIVE
To investigate the “real world” effectiveness of Traditional Chinese Medicine (TCM) in patients with acute myocardial infarction suffering from diabetes mellitus (AMI+DM patients).METHODS
This was a retrospective cohort study. During hospitalization, the “exposure group” was defined as patients who had a TCM injection for ≥ 7 d. During follow-up, the definition of the exposure group was application of a Chinese patent medicine or decoction of Chinese medicine for ≥ 28 d. General information (age, sex, contact details), TCM use and endpoint events of AMI + DM patients during hospitalization and follow-up were collected. The correlation between TCM and the end-point events of AMI + DM patients was analyzed using a multiple logistic regression method.RESULTS
A total of 479 AMI + DM patients were enrolled and 345 cases were followed up. During hospitalization, TCM, age, hypertension and use of an angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) were associated with cardiac death. During follow-up, TCM was associated with cardiac death. TCM was a relevant factor for a composite endpoint of re-infarction and stroke. TCM, anti-thrombotic therapy and lipid-lowering therapy were related to acute heart failure. TCM, anti-thrombotic therapy, anti-MI therapy and ACEI/ARB use exhibited a strong correlation with re-hospitalization due to cardiovascular disease.CONCLUSION
TCM reduced the prevalence of cardiac death during hospitalization, and cardiac death, a composite endpoint of re-infarction and stroke, acute heart failure and re-hospitalization due to cardiovascular disease during follow-up. 相似文献12.
储藏中药材孳生粉螨的研究 总被引:2,自引:0,他引:2
目的通过中药材孳生粉螨的调查,对预防和控制中药材中孳生的粉螨提供依据。方法清水漂浮法和塔氏电热集螨器法。结果共分离中药材样品127种,1270份,从中分离出粉螨49种,隶属7科25属。结论中药材粉螨的污染严重,应加强对中药材螨类的防治,以保护中药材及预防人体螨病。 相似文献
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糖尿病及其并发症发病机制复杂,尚未完全阐明。研究发现靶细胞的损伤、凋亡,进而导致的组织损伤,是糖尿病各种并发症发生、发展的重要因素。Bax是重要的细胞凋亡因子,其表达水平的异常,与糖尿病各种并发症发生、发展密切相关。研究发现单味中药或复方,可通过降低糖尿病并发症靶细胞中bax表达水平,改善靶细胞功能,保护靶细胞结构,降低靶细胞凋亡率,从而延缓糖尿病并发症的发生发展。现对近年来中医药调控糖尿病常见并发症中bax表达的相关实验研究进行述评,以飨同道。 相似文献
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中药材生态变异与生态型的分化和形成是物种种内对不同环境生态条件长期适应与自然选择,在形态、生理、生化上表现出差异的结果。这种种内变异是中药材品质优劣和疗效差异的实质。我国复杂多样的气候地理生态条件,形成了特有的多道地、多产地现象,即中药材生态型的多样性。中药材生态变异和生态型的分类已成为值得探索的重要科学问题。着重对生态型的定义、中药材生态变异、中药材生态型的划分等研究现状进行概述。认为中药材生态型可分为气候生态型、地理生态型、群落生态型、化学生态型、品种生态型;提出了当前中药材生态型研究面临的关键性问题,即科学把握中药材种内变异的分类学地位,中药材生态型的生态特征及影响生态型形成的决定因素,生态型与环境、品质、遗传基础的相关性及不同生态型之间的关系,并对研究思路和实施策略进行了阐述。 相似文献
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肝脏损害是由于微循环障碍、肝细胞变性坏死而引起的肝功能异常,它影响到几乎每个年龄段人群肝脏细胞的重要生物活性,而常规用药来抑制肝脏损害是远远不够的。而且,由于对抗疗法所用药物往往具有肝毒性,反而加剧了肝脏功能的紊乱。为了寻找安全有效的替代药物,人们逐渐把目光转向了具有保肝作用的药用植物,并对其进行系统性的方法学研究和药用原理评估。药用植物治疗肝病具有悠久的历史,最早可追溯到公元前2100年的中国夏朝和古印度吠陀时期,但是能证明那个时期药用植物有效治疗肝病的证据却很难寻觅。本文旨在系统性地概述现今在临床治疗和实验研究中最常用以及最有效的保肝类药用植物。 相似文献
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Ibrahim Chikowe Andrew G Mtewa David Tembo Dallas Smith Edna Ibrahim Bonface Mwamatope Justin Nkhungulu Peter Kumpalume Alfred Maroyi 《Malawi medical journal : the journal of Medical Association of Malawi》2021,33(2):85
The Coronavirus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered an international pandemic that has led to significant public health problems. To date, limited evidence exists to suggest that drugs are effective against the disease. As possible treatments are being investigated, herbal medicines have shown potential for producing novel antiviral agents for the COVID-19 disease.AimThis review explored the potential of Malawi''s traditional medicinal plants for the management of COVID-19.MethodsThe authors searched on PubMed and Google scholar for medicinal plants that are used in Malawi and published in openly available peer reviewed journals. Plants linked with antiviral treatment, anti-COVID-19 activity or COVID-19 symptoms management were targeted. These included activity against pneumonia, inflammation, cough, difficulty in breathing, pain/aches, fever, diarrhoea, rheumatism, fatigue, asthma, immunocompromised and cardiovascular diseases.Results11 studies were found with 306 plant species. 127 plant species had at least one COVID-19 related pharmacological activity. Of these plant species, the number of herbal entities used for each indication was: pain/aches (87), fever (2), pneumonia (9), breathing/asthma problems (5), coughing (11), diarrhoea (1), immunosuppression (8), blood issues (10), fatigue (2), heart problems (11), inflammation (8), rheumatism (10) and viral diseases (12). Thirty (30) species were used for more than one disease and Azedarachta indica topped the list (6 of the 13 COVID-19 related diseases). The majority of the species had phytochemicals known to have antiviral activity or mechanisms of actions linked to COVID-19 and consequent diseases'' treatment pathways.ConclusionMedicinal plants are a promising source of compounds that can be used for drug development of COVID-19 related diseases. This review highlights potential targets for the World Health Organization and other research entities to explore in order to assist in controlling the pandemic. 相似文献
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上海市2型糖尿病患病情况现状调查 总被引:44,自引:0,他引:44
Li R Lu W Jia WP Li YY Shi L Liu MX Geng GZ Fu H Shi R Shi JH Shi HL Zhang SN 《中华医学杂志》2006,86(24):1675-1680
目的 了解上海市社区居民2型糖尿病、糖调节异常(IGR)患病率及其分布特征。方法 采用多阶段整群随机抽样方法,对上海市城、乡社区居民15-74岁者进行横断面的调查。结果 上海市居民2型糖尿病、糖耐量低减(IGT)和空腹血糖受损(IFG)患病率分别为8.6%(1000/11589)、6.9%(802/11589)和1.0%(120/11589)(标化率为6.2%、5.1%和0.8%)。超重、肥胖人群中2型糖尿病患病率为11.5%(454/3946)和16.3%(207/1273),IGT患病率为8.9%(352/3946)和12.0%(153/1273),IFG患病率为1.4%(57/3946)和2.3%(29/1273),明显高于体质指数正常人群[分别为5.3%(337/6364),4.6%(294/6364),0.5%(34/6364)](均P〈0.01)。中心性肥胖人群中2型糖尿病患病率为16.5%(525/3173),IGT患病率为11.7%(372/3173),IFG患病率为1.6%(52/3173),明显高于无中心性肥胖人群[分别为5.6%(475/8416),5.1%(430/8416),0.8%(68/8416)](均P〈0.01)。高血压人群中2型糖尿病患病率为17.4%(479/2752)、IGT患病率为11.0%(303/2752)、IFG患病率为2.0%(56/2752),明显高于无高血压人群[分别为5.9%(521/8837),5.6%(499/8837),0.7%(64/8837)](均P〈0.01)。男性2型糖尿病、IGT和IFG患病率分别为8.9%(412/4621)、6.4%(296/4621)和1.0%(47/4621),女性2型糖尿病、IGT和IFG患病率分别为8.4%(588/6968)、7.3%(506/6968)和1.0%(73/6968),2型糖尿病、IGT和IFG患病率在男女之间差异无统计学意义(均P〉0.05)。城市2型糖尿病、IGT和IFG患病率分别为11.2%(730/6500)、6.4%(419/6500)和1.2%(77/6500)(标化率分别为6.5%、4.9%和0.8%),农村2型糖尿病、IGT和IFG患病率分别为5.3%(270/5089)、7.5%(383/5089)和0.8%(43/5089)(标化率分别为3.8%、5.4%和0.7%),城乡之间2型糖尿病和IGT患病率差异有统计学意义(P〈0.05),IFG患病率差异无统计学意义(P=0.073)。新诊断2型糖尿病比例为47.6%,其中农村为69.3%(187/270),明显高于城市[39.6%(289/730)](P〈0.01)。结论 上海市DM患病率呈快速增长趋势,应注重对富裕起来的农村地区居民的早期2型糖尿病筛查。 相似文献