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1.
化疗是妇科恶性肿瘤治疗的重要手段之一。随着新的有效化疗药物的不断问世和医学模式的转变,化疗在妇科恶性肿瘤治疗中的价值也发生了很大的变化,已开始从妇科恶性肿瘤辅助性治疗向主导性治疗过渡,化疗与手术、放疗和免疫治疗相结合的综合治疗也已成为妇科恶性肿瘤治疗的发展趋势。在妇科恶性肿瘤的治疗中,如何合理应用化疗,充分发挥其治疗作用,减少其严重毒副反应,是临床极为关注的问题。针对目前妇科肿瘤化疗存在的相关问题,中华医学会妇科肿瘤学分会和《中华妇产科杂志》编委会于2005年8月25-27日在新疆维吾尔自治区乌鲁木齐市联合召开了第二次全国妇科肿瘤化疗学术会议。到会的专家和代表们就妇科肿瘤化疗的现状、存在的问题和发展方向进行了广泛和深入的探讨,并提出很多建设性意见和解决问题的办法。这次会议的召开很及时也很有意义,对合理应用妇科恶性肿瘤化疗具有规范和指导作用。  相似文献   

2.
《中华妇产科杂志》2004,39(9):630-630
由中华医学会《中华妇产科杂志》编委会主办的“第二届全国妇科恶性肿瘤化疗及其相关问题”研讨会,原定于2004年9月在新疆乌鲁木齐市举行,因故改至2005年8月举行(地点不变)。会议将邀请全国著名专家和学者对妇科恶性肿瘤化疗及其相关问题进行学术交流及专题讲座,内容包括:(1)妇科恶性肿瘤化疗国内、外进展;(2)化疗相关理论(包括细胞周期、药代动力学等);(3)卵巢恶性肿瘤、恶性滋养细胞肿瘤、子宫内膜癌、宫颈癌等的化疗;(4)化疗途径  相似文献   

3.
子宫颈癌的综合治疗   总被引:1,自引:0,他引:1  
宫颈癌是常见的妇科恶性肿瘤。早期治疗效果较好,中、晚期患者不适合手术治疗,单纯放疗效果也不理想。根据文献报道,晚期宫颈癌的治疗效果迄今仍较差,长期生存率不超过40%,无复发的生存率  相似文献   

4.
《中华妇产科杂志》2004,39(10):654-654
由中华医学会《中华妇产科杂志》编委会主办的“第二届全国妇科恶性肿瘤化疗及其相关问题”研讨会,原定于2004年9月在新疆乌鲁木齐市举行,因故改至2005年8月举行(地点不变)。会议将邀请全国著名专家和学者对妇科恶性肿瘤化疗及其相关问题进行学术交流及专题讲座,内容包括:(1)妇科恶性肿瘤化疗国内、外进展;(2)化疗相关理  相似文献   

5.
《中华妇产科杂志》2004,39(11):724-724
由中华医学会《中华妇产科杂志》编委会主办的“第二届全国妇科恶性肿瘤化疗及其相关问题”研讨会,原定于2004年9月在新疆乌鲁木齐市举行,因故改至2005年8月举行(地点不变)。会议将邀请全国著名专家和学者对妇科恶性肿瘤化疗及其相关问题进行学术交流及专题讲座,内容包括:(1)妇科恶性肿瘤化疗国内、外进展;(2)化疗相关理  相似文献   

6.
由中华医学会妇科肿瘤学分会、《中华妇产科杂志》编委会联合主办,新疆维吾尔自治区医学会承办的第二届全国妇科恶性肿瘤化疗及其相关问题学术研讨会于2005年8月25—27日在乌鲁木齐市召开。此次会议共收到论文300余篇,来自全国各地的近400位代表出席了本次会议。中会医学会妇科肿瘤学分会主任委员、《中华妇产科杂志》名誉总编辑曹泽毅教授,中会医学会妇产科学分会主任委员、《中华妇产科杂志》总编辑郎景和教授,以及新疆维吾尔自治区医学会副秘书长唐培作教授等在开幕式上致辞。  相似文献   

7.
放化疗综合治疗宫颈癌的评价   总被引:2,自引:0,他引:2  
宫颈癌是妇女第二大常见恶性肿瘤,其治疗早期以手术为主,中晚期以放射治疗为主,总的5年生存率为50%左右。尽管多年来不断提高手术技巧,改进放疗技术,但治疗后仍有较高的复发率。其原因与手术和放疗均为局部治疗手段,难以消灭潜在的亚临床病灶和微转移灶有关。随着化疗的研究进展,化疗已逐步成为宫颈癌综合治疗中一个重要的组成部分。据FIGO 2003年报,1996—1998年间,世界各国对各期宫颈癌给予术前或放疗前化疗(新辅助化疗)、术前放疗及放化疗同期进行的比例逐渐增高,初步形成了手术、放疗、化疗相结合的综合治疗模式。  相似文献   

8.
妇科恶性肿瘤的放射治疗——宫颈癌术前放射治疗   总被引:4,自引:0,他引:4  
手术和放疗是子宫颈癌主要治疗手段。局部晚期即预后不良型巨块状宫颈癌及淋巴结转移是影响可手术治疗宫颈癌预后的主要因素。目前,有许多研究认为,术前放疗可以减少肿瘤局部复发,提高存活率。  相似文献   

9.
腹腔镜手术治疗妇科恶性肿瘤的适应证与并发症   总被引:9,自引:0,他引:9  
越来越多的研究结果显示,手术治疗早期妇科恶性肿瘤,不但可以减少患者的死亡率及肿瘤复发的机会,也可使患者术后的生活质量明显提高,尤其与单纯放疗比较时,更为明显。因此,到目前为止,手术治疗仍是妇科恶性肿瘤最好的治疗方式,而腹腔镜用于妇科恶性肿瘤的手术治疗,具有创伤小、恢复快等优点,因而成为越来越普及的治疗模式。  相似文献   

10.
妇科恶性肿瘤治疗后性激素应用的风险和效益评价   总被引:1,自引:0,他引:1  
性激素治疗(HT)已应用几十年,其改善围绝经期症状、预防骨质疏松(OS)等疗效已被公认,但在妇科恶性肿瘤患者治疗后的应用仍是一个极具挑战性的课题.尤其是随着现代医学的发展,部分妇科恶性肿瘤患者的治愈率和无瘤生存率明显提高,然而伴随着肿瘤手术或后续的治疗将使绝大多数患者,尤其是年轻患者失去卵巢功能.此类患者术后低雌激素状态所致的临床症状可严重影响其生活质量.  相似文献   

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Neuroendocrine tumors (NETs) are aggressive diseases developing from neuroendocrine cells that most frequently involve the gastro-entero-pancreatic tract and the lung, but more rarely are found in almost all body tissues. Limited biological and clinical data are currently available for NETs in uncommon sites, such as female genital tract. NETs represent 0.9% to 1.5% of the tumors of the uterine cervix. They are more likely to have lymph-vascular space invasion and lymph node involvement, and to develop local and distant relapses when compared with the mostly common cervical squamous cell carcinomas or adenocarcinomas. Positive immunostaining for synaptophysin, chromogranin, CD56, and neuron-specific enolase is often detected in cervical NETs .The most recent editions of the World Health Organization Classification of Gynecologic Tract tumors grouped cervical carcinoid tumor and atypical carcinoid tumor into low-grade NETs and cervical small cell neuroendocrine carcinoma and large cell neuroendocrine carcinoma into high-grade NETs. High-risk HPV DNA is detected in almost all cervical high-grade NETs. No treatment guidelines, based on prospective, well-designed clinical trials, are currently available due to the rarity of these tumors. Many authors have reported different multimodality approaches, mainly derived from NETs of the lung. These usually consist in radical hysterectomy followed by adjuvant chemotherapy or concurrent chemoradiation for early stage disease, definitive concurrent chemoradiation sometimes preceded by neoadjuvant chemotherapy and followed by adjuvant chemotherapy for locally advanced disease, and palliative chemotherapy for metastatic disease. In this systematic review, we address the histologic classification of cervical NETs, analyze their pathogenesis and overall prognosis, and evaluate the different treatment modalities described in the literature, in order to offer a possible algorithm that may help the clinicians in diagnosing and treating patients with these uncommon and aggressive malignancies.  相似文献   

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14.
妊娠合并妇科恶性肿瘤期待至妊娠结束后处理   总被引:2,自引:0,他引:2  
妊娠合并妇科恶性肿瘤较少见。据美国的统计数据,妊娠合并恶性肿瘤发生率约3.3/万,依次为乳腺癌、甲状腺癌、子宫颈癌、何杰金病及卵巢癌[1]。国内缺乏大样本的统计数据。妇科恶性肿瘤常用的治疗手段如手术、化疗、放疗都将影响继续妊娠和胎儿健康。在妊娠期发现妇科肿瘤,一般根据肿瘤的良恶性、孕周、患者及家属对胎儿的考虑等综合因素作出治疗选择,有少数患者会选择妊娠结束后再处理肿瘤。1宫颈癌1.1妊娠合并宫颈癌妊娠期期待的可行性我国是宫颈癌的高发地区,妊娠合并宫颈癌的发生率约为0.92%~7.05%。由于手术或放疗都会影响胎儿结局,以往…  相似文献   

15.
Clinical and potential applications of ultrasonic therapy for gynecologic tumors are overviewed in this minireview. As a noninvasive technique, extracorporeal high-intensity focused ultrasound was clinically used to treat uterine myomas. High-intensity focused ultrasound treats leiomyomas via shrinkage of tumor size, reduction of blood supply, and suppression of cell proliferation, resulting in a relief of symptoms and improvement of quality of life. Preclinical trials have confirmed that ultrasound enhanced a cytotoxic agent against cancers of ovary and cervix; insonation overcomes doxorubicin (adriamycin) and cisplatin resistance in ovarian cancers, suggesting a modality for refractory lesions; ultrasonic hyperthermia induces high temperature increase in deeper cancer tissues thus being a potential modality for treatment of cervical cancers. Transvaginal ultrasonic therapy can be applied for a lesion near the cervix. In summary, ultrasonic therapy is a promising treatment modality for gynecologic tumors, and might change clinical practices.  相似文献   

16.
Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%. Pleural effusions usually occur at a stage of the disease where no further curative therapeutic options exist. Therefore, the treatment should be effective and have a low side effect profile. The intrapleural administration of mitoxantrone in comparison with other pleurodesis techniques has been demonstrated to meet these requirements.  相似文献   

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Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%. Pleural effusions usually occur at a stage of the disease where no further curative therapeutic options exist. Therefore, the treatment should be effective and have a low side effect profile. The intrapleural administration of mitoxantrone in comparison with other pleurodesis techniques has been demonstrated to meet these requirements.  相似文献   

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Positron emission tomography (PET) using fluorine-18-fluoro-2-deoxy-d-glucose (FDG), which originated as a research tool to evaluate glucose metabolism in cancer tissues, has now become an essential imaging modality for determining the appropriate therapeutic management of various cancer patients. The clinical role of FDG-PET for gynecologic tumors has not been established yet, but FDG-PET has come to be considered one of the important imaging modalities for evaluating patients with gynecological cancers. The objective was to review the literature regarding the utility of FDG-PET in the clinical setting of gynecological malignancies. Many articles reported that FDG-PET could be used for staging and restaging in patients with uterine cervical cancer. Although there is limited data about the feasibility of FDG-PET for endometrial cancer, preliminary results for detecting recurrence were promising. Furthermore, FDG-PET has been reported as a useful imaging modality, especially for restaging, in ovarian cancer, although the prognostic value needs to be fully investigated. Currently, a combined PET/computed tomography scanner is available, and its clinical application has begun. It is expected that this modality will contribute to the management of gynecological cancers, as has been reported recently for other malignancies.  相似文献   

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