孕妇产前抑郁影响因素研究

目的:用Logistic回归模型分析孕中期妇女(妊娠12～28周)抑郁的影响因素。方法:对870例孕妇进行爱丁堡抑郁量表(Edinburgh Postnatal Depression Scale,EPDS)调查,并进行孕妇基本信息(生理状态、经济水平、工作状态、文化水平、病史、家庭支持状况)采集,用单因素分析、Logistic回归分析孕中期妇女抑郁的影响因素,并进行模型拟合与评估。结果:280例(32.2%)孕妇可能存在产前抑郁情绪(EPDS评分≥13分),单因素分析和Logistic回归分析显示家庭支持情况,尤其是配偶父母的支持直接影响孕妇抑郁状况(P<0.05);工作状态、文化程度、生理状态、经济水平和病史对抑郁的影响无统计学意义(P>0.01)。结论:家庭支持是孕妇抑郁的影响因素。     

Perinatal depressive symptoms among Arab women in northern Israel

Perinatal depression, a prevalent condition with negative consequences for the mother, infant and family, has been reported in many countries. This study aimed to assess the scope of depressive symptoms among pregnant and postnatal Israeli Arab women and to identify possible risk factors. Data were collected from a screening program at 58 Mother-Child Health Care clinics in northern Israel from June to December, 2009. Participants included 1,254 pregnant and 2,326 postnatal women. The rate of antenatal depressive symptoms, i.e., a score of ≥10 on the Edinburgh Postnatal Depression Scale (EPDS) was 20.8%. Women attending clinics with primarily religious or traditional populations had lower rates antenatally than did those described as secular. During the postnatal period 16.3% of the women scored ≥10 on the EPDS. The rate of postnatal depressive symptoms was significantly higher among women living in Moslem than Druze communities (EPDS ≥ 10: 19.0% vs. 13.4%, respectively, P = 0.01). Postnatally, there were no significant differences according to SES cluster, community size, or religious orientation. The rate of antenatal and postnatal depression among Arab women in northern Israel was somewhat higher than that of Jewish Israeli women in the same region, and considerably lower than that of Arab Bedouin women in southern Israel. Given the differences in their life styles and circumstances, health policy authorities should be informed regarding the needs of these various sub-populations.     

Prevalence and Correlates of Depression in Pregnancy Among Turkish Women

The aim of this study was to evaluate prevalence and correlates of depression in pregnancy among Turkish women in Sivas, a semi-urban region consisting partly of people with low or middle socioeconomic status. This cross-sectional population-based study was conducted in 19 primary health care centers from urban areas of Sivas in Turkey. Two hundred fifty-eight eligible pregnant women were interviewed at their home to gather the study data. A questionnaire was used to determine the socio-demographics and obstetric characteristics of the study sample. The Turkish version of the Edinburg Postnatal Depression Scale (EPDS) was used to estimate the prevalence of depression. The Multidimensional Scale of Perceived Social Support (MSPSS) was used to determine the social support of pregnant women. We found that with the cutoff of 13, of 258 pregnant women, 71 (27.5%) had prenatal depression. Mean EPDS score of the study population was 9.5 ± 5.2. We found a significant positive mild-moderate correlation between the EPDS score and maternal age (r = 0.30; P = 0.000). Significant positive mild correlations were found between the EPDS score and gravidity (r = 0.26; P = 0.000) and number of living children (r = 0.15; P = 0.042). There was a significant negative moderate correlation between the EPDS score and perceived social support score (r = −0.43; P = 0.000). The EPDS score of multiparas was significantly higher than that of primiparas (P = 0.000). EPDS scores of women with unplanned pregnancy were higher than those of women with planned pregnancies (P = 0.006). EPDS scores of women with a history of stillbirth were higher than those of women with no history of stillbirth (P = 0.044). Depression is a major public concern that needs to be at the forefront of antenatal assessments in Turkey as in other countries. Health professionals, especially nurses in prenatal settings, are in a unique position to detect antenatal depression. Nurses need to monitor pregnant women for depressive symptoms, especially those who are at increased risk of developing depression.     

High prevalence of depression symptomology among adolescents in Soweto,South Africa associated with being female and cofactors relating to HIV transmission

Adolescents in HIV endemic settings are a priority demographic with respect to HIV prevention. Some studies have shown that behaviours associated with HIV transmission, may be mediated by mental health factors such as depression. We undertook this study to explore the prevalence and associations of depression symptomology among adolescents living in the HIV endemic community of Soweto, South Africa through the Botsha Bophelo Adolescent Health Study (BBAHS). We estimated the prevalence of depression using the Centre for Epidemiological Studies of Depression Scale, using a score of ≥24 to indicate ‘probable depression’. Among the 789 adolescents (14–19 years) with depression scores, 262 (33%) met the criteria for probable depression (99 [38%] men and 163 [62%] women; p = 0.061). In multivariable logistic regression, factors independently associated with depression included being female (AOR = 2.44, 95% CI: 1.45–4.00), marijuana use (AOR = 2.67, 95% CI: 1.21–5.93), physical violence (AOR = 1.63, 95% CI: 1.01–2.62), pregnancy (AOR = 2.00, 95% CI: 1.03–3.88) and incarceration (AOR = 2.09, 95% CI: 0.99–4.42). These data indicate that a concerning proportion of adolescents in Soweto may be suffering from depression and those screened as potentially depressed, were more likely to be female and have cofactors relating to increased risk for HIV. As part of a comprehensive HIV prevention strategy, we recommend that depression screening for adolescents be integrated into public and school health programs that triage those suffering into treatment programs.     

Association Between Maternal Postpartum Depression and Unintentional Injury Among 4-Month-Old Infants in Japan

Objectives Unintentional injury among infants is a major public health issue; however, the relationship between unintentional infant injury and postpartum depression remains unclear. In this study, we aim to investigate the association between the two. Methods We administered an original questionnaire to mothers participating in a 3- or 4-month health check-up program (target n = 9707). This questionnaire assessed infant health, including types of unintentional injury experiences used in previous study, and maternal mental health such as postpartum depression, by the validated screening tool, the Edinburgh Postnatal Depression Scale (EPDS). Associations between infant injury and postpartum depression were assessed using logistic regression adjusted for covariates, including parental, infant, and household characteristics. Results In total, 6534 women responded to the questionnaire with valid answers on the EPDS (valid response rate, 67 %). Of the sample, 9.8 % of infants experienced unintentional injury (fall: 5.6 %; near-drowning: 1.2 %), and 9.5 % of mothers had postpartum depression (EPDS score of 9+). After adjusting for covariates, postpartum depression was significantly positively associated with any unintentional injury (odds ratio [OR] 1.59, 95 % confidence interval [CI] 1.24–2.04), and falls (OR 1.41, 95 % CI 1.02–1.95), although near-drowning was not significantly associated. Conclusion Postpartum depression might be a risk factor for unintentional injury of infants aged up to 4 months. Further prospective studies are needed to confirm the association between postpartum depression and unintentional injury of infants.     

孕期集体干预对产后抑郁症的影响

目的 探讨孕期集体干预对产后抑郁症(PPD)的作用.方法 选择在我院产检且分娩,在孕16~24周行医院焦虑-抑郁量表(HAD)筛查≥11分的438例孕妇为研究对象,分为干预组和非干预组.干预组孕妇从孕24周开始实施每周1次,每次90分钟,共6周的干预治疗,非干预组孕妇行常规孕期保健.所有研究对象在产后42天行爱丁堡产后抑郁量表(edinburgh postnatal depression scale,EPDS)测试≥12分诊断为产后抑郁症.结果 干预组产后42天HAD≥11分(有焦虑或抑郁情绪)患者比率显著低于对照组(χ2=25.22,P<0.01).干预组产妇EPDS值≥12分人数为22人,显著低于非干预组的63人,差异有统计学意义(χ2=24.51,P<0.01).结论 孕期集体干预能够缓解孕产妇焦虑-抑郁情绪,降低产后抑郁症发生率.     

Routine screening for postpartum depression

BACKGROUND: Postpartum depression (PPD) is a common and often overlooked condition. Validated screening tools for PPD exist but are not commonly used. We present the 1-year outcome of a project to implement universal PPD screening at the 6-week postpartum visit. METHODS: Universal screening with the Edinburgh Postnatal Depression Scale (EPDS) was implemented in all community postnatal care sites. One-year outcome assessments (diagnosis and treatment of PPD) were completed for a sample of the women screened using medical record review of all care they received during the first year postpartum. RESULTS: Sixty-eight (20%) of the 342 women whose medical records were reviewed had been given a documented diagnosis of postpartum depression, resulting in an estimated population rate of 10.7%. Depression was diagnosed in 35% of the women with elevated EPDS scores (> or =10) compared with 5% of the women with low EPDS scores (<10) in the first year postpartum. Treatment was provided for all women diagnosed with depression, including drug therapy for 49% and counseling for 78%. Four women were hospitalized for depression. Some degree of suicidal ideation was noted on the EPDS by 48 women but acknowledged in the chart of only 10 women, including 1 with an immediate hospitalization. The rate of diagnosis of postpartum depression in this community increased from 3.7% before the routine use of EPDS screening to 10.7% following screening. CONCLUSIONS: A high EPDS score was predictive of a diagnosis of postpartum depression, and the implementation of routine EPDS screening at 6 weeks postpartum was associated with an increase in the rate of diagnosed postpartum depression in this community.     

HIV-status disclosure and depression in the context of unintended pregnancy among South African women

Depressive symptoms are common among pregnant women living with HIV, and an unintended pregnancy may heighten vulnerability. HIV-status disclosure is thought to improve psychological well-being, but few quantitative studies have explored the relationships among disclosure, pregnancy intention and depression. Using multivariable linear regression models, we examined the impact of disclosure on depressive symptoms (Edinburgh Postnatal Depression Scale; EPDS) during pregnancy and postpartum among women who tested HIV-positive during the pregnancy in South Africa; and explored the role of pregnancy intention in this relationship. Among 350 women (median age: 27 years; 70% reporting that their current pregnancy was unintended), neither disclosure to a male partner nor disclosure to ≥1 family/community member had a consistent effect on depressive symptoms. However, pregnancy intention modified the association between disclosure to a male partner and depression during pregnancy: disclosure was associated with higher depression scores among women who reported that their current pregnancy was unintended but was associated with lower depression scores among women who reported that their pregnancy was intended. During the early postpartum period, disclosure to ≥1 family/community member was associated with higher depression scores. Counselling around disclosure in pregnancy should consider the heightened vulnerability that women face when experiencing an unintended pregnancy.     

Rates and Correlates of Depression Symptoms in a Sample of Pregnant Veterans Receiving Veterans Health Administration Care

BackgroundDepression is the most commonly diagnosed medical condition among women veterans ages 18 to 44; however, depression symptoms occurring during pregnancy have not been well-studied in this population.MethodsPregnant veterans were recruited from 15 Veterans Health Administration sites across the United States; our sample included 501 participants. Sociodemographic characteristics, military service, health status, and pregnancy related factors, as well as the Edinburgh Postnatal Depression Scale (EPDS), were collected as part of a telephone survey. Additional data were obtained from electronic health record data. We used multivariable logistic regression models to examine factors associated with an EPDS score suggestive of clinically significant depressive symptoms (≥10).FindingsPrenatal EPDS scores of 10 or greater were calculated for 28% of our sample. Our final model indicated that factors associated with decreased odds of an EPDS score of 10 or greater included spousal or partner support during pregnancy (adjusted odds ratio [aOR], 0.35; 95% confidence interval [CI], 0.16–0.77) and employment (aOR, 0.40; 95% CI, 0.24–0.67). A past diagnosis of anxiety (aOR, 2.54; 95% CI, 1.43–4.50), past antidepressant use (aOR, 3.27; 95% CI, 1.71–6.24), and active duty service (aOR, 1.91; 95% CI, 1.08–3.37) were associated with increased odds of having an EPDS score of 10 or greater.ConclusionsThis is the first quantitative estimate of depression symptoms in pregnant veterans across multiple Veterans Affairs facilities. The prevalence of depression symptomology was greater than the high end of prevalence estimates in the general pregnant population. Given that the risk of depression increases during the postpartum period, women who can be identified with depressive symptomatology during pregnancy can be offered critical resources and support before giving birth.     

Factors Associated with Depressive Symptoms in the Early Postpartum Period Among Women with Recent Gestational Diabetes Mellitus

Women with gestational diabetes mellitus (GDM) have a substantial risk of subsequently developing type 2 diabetes. This risk may be mitigated by engaging in healthy eating, physical activity, and weight loss when indicated. Since postpartum depressive symptoms may impair a woman’s ability to engage in lifestyle changes, we sought to identify factors associated with depressive symptoms in the early postpartum period among women with recent GDM. The participants are part of the baseline cohort of the TEAM GDM (Taking Early Action for Mothers with Gestational Diabetes Mellitus) study, a one-year randomized trial of a lifestyle intervention program for women with a recent history of GDM, conducted in Boston, Massachusetts between June 2010 and September 2012. We administered the Edinburgh Postnatal Depression Scale (EPDS) at 4–15 weeks postpartum to women whose most recent pregnancy was complicated by GDM (confirmed by laboratory data or medical record review). An EPDS score ≥9 indicated depressive symptoms. We measured height and thyroid stimulating hormone, and administered a questionnaire to collect demographic data and information about breastfeeding and sleep. We calculated body mass index (BMI) using self-reported pre-pregnancy weight and measured height. We reviewed medical records to obtain data about medical history, including history of depression, mode of delivery, and insulin use during pregnancy. We conducted bivariable analyses to identify correlates of postpartum depressive symptoms, and then modeled the odds of postpartum depressive symptoms using multivariable logistic regression. Our study included 71 women (mean age 33 years ± 5; 59 % White, 28 % African-American, 13 % Asian, with 21 % identifying as Hispanic; mean pre-pregnancy BMI 30 kg/m² ± 6). Thirty-four percent of the women scored ≥9 on the EPDS at the postpartum visit. In the best fit model, factors associated with depressive symptoms at 6 weeks postpartum included cesarean delivery (aOR 4.32, 95 % CI 1.46, 13.99) and gestational weight gain (aOR 1.21 [1.02, 1.46], for each additional 5 lbs gained). Use of insulin during pregnancy, breastfeeding, personal history of depression, and lack of a partner were not retained in the model. Identifying factors associated with postpartum depression in women with GDM is important since depression may interfere with lifestyle change efforts in the postpartum period. In this study, cesarean delivery and greater gestational weight gain were correlated with postpartum depressive symptoms among women with recent GDM (Clinicaltrials.gov NCT01158131).     

Relationship of perceived job strain and workplace support to antenatal depressive symptoms among pregnant employees in Taiwan

Most Taiwanese women continue to work throughout pregnancy. Few studies have investigated the prevalence of antenatal depressive symptoms in employed women and their relationship with work-related factors. We explored the relations of work-related factors, including perceived job strain and workplace support, to depressive symptoms among pregnant Taiwanese employees. During 2015–2016, we interviewed 153 employees in their third trimester of pregnancy using questionnaires to collect data on demographics, pregnancy status, physical conditions, work-related factors, family function, the Edinburgh Postnatal Depression Scale (EPDS), and health-related quality of life (HRQoL). The prevalence of antenatal depressive symptoms, based on EPDS scores≥13, was 13.7%. Pregnant employees with depressive symptoms had lower Family APGAR scores (p < 0.0001) and lower scores on all scales of the HRQoL (p < 0.05). Controlling for covariates, work-related feelings of stress and distress were associated with increased odds of antenatal depressive symptoms (Odds Ratio [OR] = 4.7, 95% confidence Interval [95% CI] = 1.3–19.9). Feeling tired at work (OR = 9.1, 95% CI = 2.3–47.0) and lack of support from colleagues (OR = 16.7, 95% CI = 2.9–53.1) were significantly associated with antenatal depressive symptoms. Such information will facilitate implementation of supportive workplace climates for pregnant employees by employers, supervisors, and occupational and environmental health nurses, which may help improve the health of pregnant employees.     

Intimate Partner Violence Associated with Postpartum Depression,Regardless of Socioeconomic Status

Objective This study examined whether socioeconomic status moderated the association between intimate partner violence (IPV) and postpartum depression among a community-based sample of women. Defining the role of poverty in the risk of postpartum depression for IPV victims enables prioritization of health promotion efforts to maximize the effectiveness of existing maternal-infant resources. Methods This cross-sectional telephone-survey study interviewed 301 postpartum women 2 months after delivery, screening them for IPV and depression [using Edinburgh Postnatal Depression Scale (EPDS)]. Socioeconomic status was defined by insurance (Medicaid-paid-delivery or not). This analysis controlled for the following covariates, collected through interview and medical-record review: demographics, obstetric history, prenatal health and additional psychosocial risk factors. After adjusting for significant covariates, multiple linear regression was conducted to test whether socioeconomic status confounded or moderated IPV’s relationship with EPDS-score. Results Ten percent of participants screened positive for postpartum depression, 21.3 % screened positive for current or previous adult emotional or physical abuse by a partner, and 32.2 % met poverty criteria. IPV and poverty were positively associated with each other (χ² (1) = 11.76, p < .001) and with EPDS score (IPV: beta 3.2 (CI 2.0, 4.5) p < .001, poverty: beta 1.3 (CI 0.2, 2.4) p = .017). In the multiple linear regression, IPV remained significantly associated, but poverty did not (IPV: adjusted beta 3.1 (CI 1.8, 4.3) p < .001, poverty: adjusted beta 0.8 (CI ?0.3, 1.9) p = .141), and no statistically significant interaction between IPV and poverty was found. Conclusions Study findings illustrated that IPV was strongly associated with postpartum depression, outweighing the influence of socioeconomic status upon depression for postpartum women.     

Perceived Financial Satisfaction,Health Related Quality of Life and depressive Symptoms in Early Pregnancy

Objectives To assess the associations of perceived financial satisfaction and health-related quality of life (HRQoL) and depressive symptoms in an unselected pregnant population in early pregnancy. Methods 750 consecutive pregnant women attending the first communal ultrasound examination before gestational week 14 were invited to participate. Questionnaires assessing HRQoL (15D), depressive symptoms (Edinburgh Depression Scale, EPDS), medical, obstetric, and socioeconomic status were handed out. The participants were divided into three groups according to their satisfaction with their financial status, (unsatisfied, somewhat satisfied, and satisfied). Main outcome measures were 15D and EPDS-scores and dimensions of HRQoL. Results 325 (43,3%) questionnaires were returned. The mean 15D-score for HRQoL was 0,926 (SD 0,056). The financially unsatisfied women had lower HRQoL than women in more satisfied groups (0.906, 0.923 and 0.931, p?=?0.012). The result remained significant, even after adjusting for age and education(p?=?0.032). The unsatisfied women had a higher mean body mass index (BMI) (25.4, 24.4 and 23.2 kg/m², p for linearity?=?0.002), were more often smokers, (13 vs. 4 and 3%, p?=?0.029), and had experienced at least one abortion (18, 14 and 7%, p?=?0.017). Dimensions of depression, distress and sleep explained the differences between the groups. 27% of unsatisfied women scored EPDS ≥10 points suggesting increased risk of depression. Conclusions Financial satisfaction in early pregnancy associates with HRQoL and risk of perinatal depressive symptoms. Unsatisfied women more often have risk factors for unfavourable pregnancy outcomes which may influence the later health and wellbeing of the mother and child.     

孕期健康教育对产后抑郁症发病的影响

目的:探讨孕期健康教育对产后抑郁症发病的影响。方法:随机抽取2007年1～10月在济南市妇幼保健院进行产后6周复查的520例产妇,对其进行问卷调查,包括一般情况和Edinburgh产后抑郁量表(EPDS),所有资料采用SPSS11.5统计软件进行处理,并做统计学分析。结果:①EPDS评分≥13分诊为产后抑郁症,472例中,产后抑郁症85例,检出率为21.96%。②多因素非条件Logistic回归分析结果显示,孕期保健知识(P=0.003)、孕期产后抑郁症的相关宣教(P=0.045)、家人的帮助(P=0.001)、担心孕期并发症(P=0.035)与产后抑郁症相关,有统计学意义,其OR值分别为0.392、0.601、0.373、1.594。结论:产后抑郁症病因复杂,影响因素多。孕期健康教育是产后抑郁症的保护性因素,加强孕期健康教育有助于预防产后抑郁症的发生。     

农村孕妇产后抑郁症的相关因素分析

目的：探索本省农村孕妇发生产后抑郁症的相关因素，便于指导基层妇幼保健院（所）护理人员及农村妇幼保健人员对孕产妇提供恰当的心理保健和护理。方法：随机抽取1998年1月－1999年12月在山区县妇幼保健院就诊的孕妇396例，进行孕期情绪测定（HAD），以产后抑郁量表（EPDS）进行产后跟踪调查至产后7天内370例，3个月12例，6个月4例，1年10例。结果：孕期焦虑情绪发生率为6．06％，抑郁情发生率8．08％，产后抑郁症的发生率14．65％，与1997年我省城市调查结果5．13％，4．37％和15．01％相近.结论：要降低农村孕妇产后抑郁症发生率，首先应规范农村孕妇孕期保健并加强孕期心理护理；随之加强产时服务并提倡自然分娩，最后抓住农村社区重点护理人群及其要素实施有针对性的身心护理和面对面的健康教育。     

Prolonged Exclusive Breastfeeding Through Peer Support: A Cohort Study From a Community Outreach Project in Swaziland

Swaziland faces great public health challenges, including suboptimal breastfeeding practices and the world’s highest prevalence of HIV. The objective of this study was to estimate neonatal and infant mortality rate and rate of exclusive breastfeeding for clients enrolled in a community-based peer support project in peri-urban areas of Swaziland. The intervention builds on the so called “Philani-model” with Mentor Mothers in the community under high level of supervision. Cohort data was collected from journals kept by the Mentor Mothers. Kaplan–Meier and Cox regression were used to analyse data. Neonatal and infant mortality were estimated to 15 respectively 57 per 1000 live births. High level of social vulnerability was associated with risk of neonatal mortality (HR 1.12, CI 95 % 1.01–1.24) while the mother’s positive HIV status was associated with infant mortality (HR 2.05, CI 95 % 1.15–3.65). More visits by a Mentor Mother could not be shown to result in lower mortality. The chance to practice exclusive breastfeeding for 6 months was estimated to 50 %. The risk of discontinuing exclusive breastfeeding before 6 months was lower for mothers being unemployed (HR 0.55, CI 95 % 0.44–0.69) or socially vulnerable (HR 0.95, CI 95 % 0.92–0.99) and higher for mothers being HIV positive (HR 1.22, CI 95 % 1.01–1.48). Receiving at least four visits by a Mentor Mother during pregnancy decreased the risk of discontinuing exclusive breastfeeding prematurely (HR 0.82, CI 95 % 0.67–0.99). Peer support with Mentor Mothers thus had a positive impact on exclusive breastfeeding rates in this disadvantaged population.     

The Correlation Between Postpartum Depression and Health Status

To investigate a purported correlation between postpartum depression and self-rated maternal general health status in a sample of mothers in Southern Brazil. As part of this process, the Personal Health Scale (PHS), a self-rated health status measure, was tested for the first time among postpartum women. Research volunteers completed the Structured Clinical Interview for DSM-IV Disorders (SCID), the 12-item General Health Questionnaire (GHQ), the PHS, the Postpartum Depression Screening Scale (PDSS), and the Edinburgh Postnatal Depression Scale (EPDS). Correlation coefficients were computed among the scores of the health status questionnaires and the postnatal depression scales. Bivariate linear regression analyses were conducted to evaluate the prediction of scores of postnatal depression scales having the scores of health status questionnaires as predictors. Significant correlations among both health status questionnaires and both postnatal screening tools attest to a significant interconnection between the expression of depressive symptoms and maternal health status in the postpartum period. The health status measures predicted the scores of postpartum depression scales. This study demonstrates that both general health questionnaires and postpartum depressive rating scales are useful tools for detecting depressive phenomena in postpartum women. The association between self-rated health measures and postpartum depression may be even more significant in the context of socioeconomic deprivation.     

324例产后抑郁症患者的发病因素分析及社区医疗干预效果

目的：探讨产后抑郁症的相关发病因素,为社区干预性治疗提供理论依据。方法：对324例产妇采用Edinburgh产后抑郁量表（EPDS） 及自行设计的调查表进行回顾性调查分析。结果：产后抑郁症的发生率为11.42%（37例）,夫妻感情、家庭条件和亲人关怀是产后抑郁症发生的重要影响因素（P＜0.05）;分娩年龄、分娩方式和妊娠妇女的文化程度可能是产后抑郁症发病的相关因素,但无统计学意义;社区干预治疗28例患者（75.7%）抑郁症状明显改善。结论：社区医疗工作者为妊娠妇女提供产前产后的医疗干预以及有效的社会支持是预防和降低妊娠妇女产后抑郁发病率的重要手段。     

成都地区孕产妇孕晚期和产后抑郁随访研究

目的 随访成都地区孕产妇孕晚期和产后抑郁状态,比较不同时点抑郁率,分析孕晚期和产后抑郁的关系。方法 选择2013年10月~2014年2月,在四川大学华西第二医院门诊部进行产前检查的孕晚期妇女作为研究对象,以爱丁堡产后抑郁量表（Edinburgh postnatal depression scale,EPDS）为主要研究工具,分别在孕晚期、产后8周和18周评估抑郁症状。以13分为筛查有无抑郁症状的临界值。用广义估计方程分析不同时点抑郁率和EPDS得分,用单因素Logistic回归分析孕晚期抑郁和产后抑郁的关系。结果 共纳入2 057位孕晚期妇女,其中1 665例完成产后8周随访,1 440例完成产后18周随访。孕晚期、产后8周和18周抑郁率分别为13.8%、2.2%和1.7%,抑郁率间差异有统计学意义（χ2=181.448,P<0.001）。孕晚期抑郁与产后抑郁有关（OR=3.88,95%CI:2.17~6.94,P<0.001）。孕晚期得分（8.35±3.93）最高,产后8周（3.05±3.28）次之,产后18周（2.21±3.03）最低。孕晚期得分与产后8周、18周得分均呈正相关,相关系数分别为0.358和0.128。结论 随访人群孕晚期抑郁率高于产后抑郁率,且孕晚期抑郁与产后抑郁相关,孕晚期抑郁应被给予更多关注。     

中国孕产妇不同时点抑郁状态转归及持续抑郁状态影响因素分析

目的:了解孕产妇在孕产期不同阶段的抑郁状况与各时点的自然转归情况,分析其影响因素。方法:中国疾病预防控制中心妇幼保健中心联合北京市海淀区妇幼保健院、山西省妇幼保健院、吉林省妇幼保健院、广东省珠海市妇幼保健院和广东省深圳市妇幼保健院5家妇幼保健机构共同构建了中国孕产妇心理健康队列研究,于2015年8月1日至2016年10...