New compounds from an extract of Vernonia colorata leaves with anti-inflammatory activity

Bioassay-directed fractionation of an anti-inflammatory CHCl(3)-MeOH (9:1) extract of leaves of Vernonia colorata, using a carrageenan-induced rat paw model, led to the isolation of six new compounds (1-6).These were assigned as two new androst-8-en glycosides, 3-O-[beta-d-galactopyranosyl-(1-2)-[beta-d-glucopyranosyl-(1-->6)]-beta-d-glucopyranoside]-5alpha,14alpha-androst-8-ene (1) and 3-O-[beta-d-glucopyranosyl-(1-->6)-beta-d-glucopyranoside]-5alpha,14alpha-androst-8-ene (2), two new stigmastane-type glycosides, 3beta,21,24-trihydroxy-21,23;22,28;26,28-triepoxy-5alpha-stigmasta-8(9),14(15)-dien-3-O-beta-d-galactopyranosyl-(1-->2)-beta-d-glucopyranoside (3) and 3beta,21,24-trihydroxy-21,23;22,28;26,28-triepoxy-5alpha-stigmasta-8(9),14(15)-dien-3-O-beta-d-galactopyranosyl-(1-->2)-beta-d-(6-acetyl)glucopyranoside (4), and two new stigmastane-type steroids, 3beta,25,29-trihydroxy-5alpha-stigmasta-8(9),14(15),24Z(28)-triene (5) and 3beta,23,25-trihydroxy-24,28-epoxy-5alpha-stigmasta-8(9),14(15)-diene (6). The structures of 1-6 were elucidated by spectral and chemical studies. Compounds 1-6 were tested for the anti-inflammatory activity, but all were inactive or weakly inactive as anti-inflammatory agents.     

Bacopaside III,bacopasaponin G,and bacopasides A,B, and C from Bacopa monniera

Two new saponins, 3-O-[6-O-sulfonyl-beta-d-glucopyranosyl-(1-->3)]-alpha-l-arabinopyranosyl pseudojujubogenin (1) and 3-O-[alpha-l-arabinofuranosyl-(1-->2)]-alpha-l-arabinopyranosyl jujubogenin (2), a new matsutaka alcohol derivative, (3R)-1-octan-3-yl-(6-O-sulfonyl)-beta-d-glucopyranoside (3), a new phenylethanoid glycoside, 3,4-dihydroxyphenylethyl alcohol (2-O-feruloyl)-beta-d-glucopyranoside (4), and a new glycoside, phenylethyl alcohol [5-O-p-hydroxybenzoyl-beta-d-apiofuranosyl-(1-->2)]-beta-d-glucopyranoside (5), were isolated from Bacopa monniera. Their structures were established by NMR, MS, and chemical methods.     

Inhibitors of osteoclast differentiation from Cephalotaxus koreana

Three new flavonoid glycosides ( 1- 3), 11-hydroxyhainanolidol ( 4), and a new dibenzylbutyrolactone lignan glycoside ( 5) were isolated from the aerial parts of Cephalotaxus koreana Nakai, along with 19 known flavonoids. The structures of the new compounds were elucidated using spectroscopic evidence, primarily NMR and MS. Twenty-four compounds were isolated, and among these isoscutellarein 5-O-beta-D-glucopyranoside ( 3), apigenin ( 6), kaempferol 3-O-alpha-L-rhamnopyranosyl(1'-->6')-beta-D-glucopyranoside ( 7), tamarixetin 3-O-alpha-L-rhamnopyranosyl(1'-->6')-beta-D-glucopyranoside ( 8), quercetin 3-O-[6'-O-acetyl]-beta-D-glucopyranoside ( 9), and quercetin 3-O-alpha-L-rhamnopyranoside ( 10) showed significant inhibitory activities against osteoclast differentiation at concentrations of 0.1 and 1.0 microg/mL.     

Tetranorclerodanes and clerodane-type diterpene glycosides from Dicranopteris dichotoma

The acetone extract of Dicranopteris dichotoma afforded two new tetranorclerodanes, 18-hydroxyaylthonic acid (1) and 18-oxo-aylthonic acid (2), and four new clerodane-type diterpene glycosides, (6S,13S)-6-O-[6-O-acetyl-beta-d-glucopyranosyl-(1-->4)-alpha-l-rhamnopyranosyl]cleroda-3,14-dien-13-ol (3), (6S,13S)-6-O-[4-O-acetyl-beta-d-glucopyranosyl-(1-->4)-alpha-l-rhamnopyranosyl]cleroda-3,14-dien-13-ol (4), 6-O-[6-O-acetyl-beta-d-glucopyranos-yl-(1-->4)-alpha-l-rhamnopyranosyl]-(13E)-cleroda-3,13-dien-15-ol (5), and 6-O-[beta-d-glucopyranosyl]-(1-->4)-alpha-l-rhamnopyranosyl-(13E)-cleroda-3,13-dien-15-ol (6), together with two known compounds, aylthonic acid (7) and (6S,13S)-cleroda-3,14-diene-6,13-diol (8). The structures of these new compounds were established by a combination of 1D and 2D NMR techniques, MS, and acid hydrolysis. Compound 8 showed modest anti-HIV-1 activity.     

Bioactive constituents from Boswellia papyrifera

Phytochemical investigation of the stem bark extract of Boswellia papyrifera afforded two new stilbene glycosides, trans-4',5-dihydroxy-3-methoxystilbene-5-O-{alpha-L-rhamnopyranosyl-(1-->2)-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (1), trans-4',5-dihydroxy-3-methoxystilbene-5-O-[alpha-L-rhamnopyranosyl-(1-->6)]-beta-D-glucopyranoside (2), and a new triterpene, 3alpha-acetoxy-27-hydroxylup-20(29)-en-24-oic acid (3), along with five known compounds, 11-keto-beta-boswellic acid (4), beta-elemonic acid (7), 3alpha-acetoxy-11-keto-beta-boswellic acid (8), beta-boswellic acid (9), and beta-sitosterol (10). The stilbene glycosides exhibited significant inhibition of phosphodiesterase I and xanthine oxidase. The triterpenes (3-9) exhibited prolyl endopeptidase inhibitory activities.     

凤尾草中黄酮类化学成分研究

目的研究凤尾草的化学成分。方法应用硅胶、Sephadex LH-20等柱色谱对凤尾草化学成分进行分离、纯化,根据理化常数和波谱分析鉴定化合物结构。结果从凤尾草乙酸乙酯及水部位分离鉴定了9个黄酮类化合物,分别为芹菜素(1),芹菜素7-O-β-D-葡萄糖苷(2),野漆树苷(3),芹菜素7-O-β-D-葡萄糖-4’-O-α-L-鼠李糖(4),新西兰牡荆苷(5),木犀草素(6),木犀草素7-O-β-D-葡萄糖苷(7),忍冬苷(8),木犀草素-6-C-β-D-葡萄糖-8-C-β-D-木糖苷(9)。结论化合物3及8为首次从该植物中分离得到,化合物5及9为首次从凤尾蕨科中分离得到。     

Kinmoonosides A-C, three new cytotoxic saponins from the fruits of Acacia concinna, a medicinal plant collected in myanmar

Three genuine saponins, named kinmoonosides A-C (1-3), have been isolated, together with a new monoterpenoid (4), from a methanolic extract of the fruits of Acacia concinna. The structures of kinmoonosides A-C were elucidated on the basis of spectral analysis as 3-O-?alpha-L-arabinopyranosyl(1-->6)-[beta-D-glucopyranosyl(1-->2) ]-b eta-D-glucopyranosyl?-21-O-?(6R, 2E)-2-hydroxymethyl-6-methyl-6-O-[4-O-(2'E)-6'-hydroxyl-2'-hydroxymet hyl-6'-methyl-2',7'-octadienoyl-beta-D-quinovopyranosyl]-2, 7-octadienoyl?acacic acid 28-O-alpha-L-arabinofuranosyl(1-->4)-[beta-D-glucopyranosyl(1-->3)]-a lpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranosyl ester (1); 3-O-?alpha-L-arabinopyranosyl(1-->6)-[beta-D-glucopyranosyl(1-->2) ]-b eta-D-glucopyranosyl?-21-O-?(6S, 2E)-2-hydroxymethyl-6-methyl-6-O-[4-O-(2'E)-6'-hydroxyl-2'-hydroxymet hyl-6'-methyl-2',7'-octadienoyl-beta-D-quinobopyranosyl]-2, 7-octadienoyl?acacic acid 28-O-alpha-L-arabinofuranosyl(1-->4)-[beta-D-glucopyranosyl(1-->3)]-a lpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranosyl ester (2); and 3-O-?alpha-L-arabinopyranosyl(1-->6)-[beta-D-glucopyranosyl(1-->2) ]-b eta-D-glucopyranosyl?-21-O-[(2E)-6-hydroxyl-2-hydroxymethyl-6-methyl- 2,7-octadienoyl]acacic acid 28-O-alpha-L-arabinofuranosyl(1-->4)-[beta-D-glucopyranosyl(1-->3)]-a lpha-L-rhamnopyranosyl(1-->2)-beta-D-glucopyranosyl ester (3), respectively. The new monoterpenoid 4 was determined as 4-O-[(2E)-6-hydroxyl-2-hydroxymethyl-6-methyl-2, 7-octadienoyl]-D-quinovopyranose. Compounds 1-3 showed significant cytotoxicity against human HT-1080 fibrosarcoma cells.     

Mixed lignan-neolignans from Tarenna attenuata

Six new mixed lignan-neolignans and 20 known compounds were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of the new compounds were elucidated as (1R,5R,6R)-6-{4-O-[2-(1-(4-hydroxy-3-methoxyphenyl))glycerol]-3,5-dimethoxyphenyl}-3,7-dioxabicyclo[3.3.0]octan-2-one (1), 5' '-methoxyhedyotisol A (2), 4' '-O-(8-guaiacylglycerol)buddlenol A (3), 5' '-methoxy-4' '-O-(8-guaiacylglycerol)buddlenol A (4), 4,6-dimethoxy-5-hydroxy-3-hydroxymethyl-2-(3,4,5-trimethoxyphenyl)-2,3-dihydrobenzofuran (5), and 7-O-ethylguaiacylglycerol (6). Compounds 1, 5, 6, and 8 showed potent antioxidant activities against H2O2-induced impairment in PC12 cells, and compounds 1, 2, 5, and 7 scavenged DPPH radical strongly with IC50 values of 72, 87, 45, and 55 microM, respectively.     

Cucurbitosides F-M, acylated phenolic glycosides from the seeds of Cucurbita pepo

Eight new phenolic glycosides, cucurbitosides F-M (1-8), were isolated from the seeds of Cucurbita pepo. Their structures were elucidated as 4-(2-hydroxyethyl)phenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (1), 4-(2-hydroxyethyl)phenyl 5-O-(3-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (2), 4-(2-hydroxyethyl)phenyl 5-O-nicotinyl-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (3), 4-(2-hydroxyethyl)phenyl 5-O-(4-aminobenzoyl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (4), 4-(2-hydroxyethyl)-2-methoxyphenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (5), 4-(hydroxymethyl)phenyl 5-O-(2-S-2-methylbutyryl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (6), 4-(hydroxymethyl)phenyl 5-O-nicotinyl-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (7), and 4-(hydroxymethyl)phenyl 5-O-(4-aminobenzoyl)-beta-d-apiofuranosyl(l-->2)-beta-d-glucopyranoside (8) on the basis of various spectroscopic analyses and analyses of hydrolysis products.     

南苜蓿的化学成分研究

 目的 研究南苜蓿的化学成分。方法 采用不同柱色谱技术反复进行分离和纯化,通过理化性质和波谱数据分析鉴定化合物结构。结果 从南苜蓿地上部分分离并鉴定出14个化合物,分别为芹菜素(1)、芹菜素-7-O-β-D-葡萄糖苷(2)、芹菜素-7-O-β-D-葡萄糖醛酸甲酯(3)、芹菜素-7-O-β-D-葡萄糖醛酸丁酯(4)、木犀草素(5)、异芒柄花素(6)、异甘草素(7)、刺囊酸-3-O-[O-α-L-鼠李糖-(1→2)-α-L-阿拉伯糖苷](8)、香豆雌酚(9)、腺嘌呤(10)、黄嘌呤(11)、正三十九烷醇(12)、胡萝卜苷(13)、β-谷甾醇(14)。结论 以上化合物均为在该植物中首次分得,其中化合物3、4、6、8、10、11、12为首次从该属植物中分得。
     

Isoflavone diglycosides from Glycosmis pentaphylla

Six new apiosyl-(1-->6)-glucosyl isoflavones (1-6) and four known ones were isolated from the stems of Glycosmis pentaphylla. The structures of the new glycosides are 3',7-dihydroxy-4',5,6-trimethoxyisoflavone 7-O-(5-O-trans-p-coumaroyl)-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (1), 2',7-dihydroxy-4',5',5,6-tetramethoxyisoflavone 7-O-(5-O-trans-p-coumaroyl)-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (2), 2',7-dihydroxy-4',5',5,6-tetramethoxyisoflavone 7-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (3), 7-hydroxy-4',8-dimethoxyisoflavone 7-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (4), 7-hydroxy-4',6-dimethoxyisoflavone 7-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (5), and 4',5-dihydroxy-3',7-dimethoxyisoflavone 4'-O-beta-D-apiofuranosyl-(1-->6)-beta-D-glucopyranoside (6). Their structures were established primarily by NMR experiments and chemical methods.     

锐尖山香圆叶化学成分的研究

 目的 研究锐尖山香圆叶(Turpinia arguta)的化学成分。方法 采用硅胶柱及Sephadex LH-20等色谱技术进行分离,利用现代波谱学技术确定化合物的结构。结果 从中分离并鉴定了13个化合物,分别为香草酸（1）,反式对羟基肉桂酸（2）,环丁二酸酐（3）,芹菜素（4）,焦没食子酸（5）,α-呋喃甲酸（6）,没食子酸（7）,2-4′-羟基-苄基-2-羟基-丁二酸（8）,木犀草素（9）,芹菜素-7-O-葡萄糖苷（10）,木犀草素-7-O-葡萄糖苷（11）,芹菜素-7-O-新橙皮糖苷（12）,芹菜素-7-O-2′-鼠李糖基芸香糖苷（13）。结论 化合物1~13均为首次从本科植物中分离得到。
     

Flavanone glycosides from Miconia trailii

Assay-guided fractionation of the ethanol extract of the twigs and leaves of Miconia trailii yielded two new flavanone glycosides, matteucinol 7-O-alpha-l-arabinopyranosyl(1-->6)-beta-d-glucopyranoside (miconioside A, 1) and farrerol 7-O-beta-d-apiofuranosyl(1-->6)-beta-d-glucopyranoside (miconioside B, 2), along with the known compounds matteucinol 7-O-beta-d-apiofuranosyl(1-->6)-beta-d-glucopyranoside (3), matteucinol (4), 2alpha,3beta,19alpha-trihydroxyolean-12-ene-24,28-dioic acid (bartogenic acid, 5), 2alpha,3beta,23-trihydroxyolean-12-ene-28-oic acid (arjunolic acid, 6), 2alpha,3alpha,19alpha, 23-tetrahydroxyurs-12-ene-28-oic acid (myrianthic acid, 7), and stigmast-4-ene-3,6-dione (8). The structures of 1-8 were elucidated by spectroscopic methods, including 2D NMR.     

Acylated flavonol glycosides from the flower of Inula britannica

Three new acylated flavonol glycosides, patuletin 7-O-(6' '-isobutyryl)glucoside (1), patuletin 7-O-[6' '-(2-methylbutyryl)]glucoside (2), and patuletin 7-O-(6' '-isovaleryl)glucoside (3), were isolated from the n-BuOH extract of Inula britannica flowers by bioassay-guided fractionation, together with other known flavonoids. The structures were elucidated by 1D and 2D NMR, FABMS, and other spectral analyses. The eight flavonoids, including new compounds (1-3), patulitrin (7), nepitrin (8), axillarin (10), patuletin (11), and luteolin (12), showed profound antioxidant activity in DPPH assay and cytochrome-c reduction assay using HL-60 cell culture system.     

紫花地丁全草化学成分研究

目的研究紫花地丁Viola yedoensis全草的化学成分。方法采用硅胶、ODS、Sephadex LH-20凝胶和半制备型高效液相等柱色谱方法进行分离纯化,通过理化性质结合NMR、MS等谱学数据分析鉴定化合物结构。结果从紫花地丁95%乙醇提取物中分离得到21个化合物,分别鉴定为秦皮乙素-6-O-β-D-呋喃芹糖基-(1→2)-β-D-吡喃葡萄糖苷(1)、吲哚-3-甲酸乙酯(2)、脱氢地芰普内酯(3)、滨蒿内酯(4)、蒲公英苦素(5)、水杨苷(6)、丁香苷(7)、4-羟基-4-[3′-(β-D-葡萄糖基)亚丁基]-3,5,5-三甲基-2-环己烯-1-醇(8)、柑橘苷A(9)、(7S,8R)-二氢去氢二松柏醇-9-O-β-D-吡喃葡萄糖苷(10)、山柰素-3-O-α-L-(4-O-乙酰基)鼠李糖基-7-O-α-L-鼠李糖苷(11)、山柰酚-7-O-α-L-鼠李糖苷(12)、山柰酚-3-O-α-L-鼠李糖苷(13)、山柰酚-3-O-α-L-鼠李糖基-7-O-α-L-鼠李糖苷(14)、山柰酚-3-O-β-D-葡萄糖苷(15)、芹菜素(16)、(+)-异地芰普内酯(17)、尿苷(18)、腺苷...     

New triterpene glycosides from the stems of Anomospermum grandifolium

Two new dammarane saponins identified as jujubogenin 3-O-alpha-l-arabinofuranosyl(1-->2)-[beta-d-glucopyranosyl(1-->6) beta-d-glucopyranosyl(1-->3)]-alpha-l-arabinopyranoside (2) and jujubogenin 3-O-alpha-l-arabinofuranosyl(1-->2)-[6-O-[3-hydroxy-3-methylglutaryl]-beta-d-glucopyranosyl(1-->3)]-alpha-l-arabinopyranoside (3) and a new lupane saponin, 3beta-hydroxylup-20(29)-en-27,28-dioic acid 28-O-beta-d-glucopyranosyl(1-->2)-[beta-d-xylopyranosyl(1-->3)]-beta-d-xylopyranosyl(1-->2)-beta-d-glucopyranoside ester (5), along with the known jujubogenin 3-O-alpha-l-arabinofuranosyl(1-->2)-[beta-d-glucopyranosyl(1-->3)]-alpha-l-arabinopyranoside (1) and 3beta-hydroxylup-20(29)-ene-27,28-dioic acid (4), were isolated from the methanol extract of the stems of Anomospermum grandifolium. The structures of the new compounds were established by spectral analysis. Antimicrobial activity screening of compounds 1-3 revealed antifungal properties against C. albicans ATCC 3153 for compounds 2 and 3. The antibacterial and antifungal activities of the petroleum ether, chloroform, and methanol extracts of A. grandifolium stems were also evaluated.     

蒙古蒲公英的化学成分研究

目的:研究蒙古蒲公英Taraxacum mongolicum的化学成分。方法:采用色谱法分离化学成分,波谱法鉴定其结构。结果:从蒙古蒲公英全草中分离并鉴定了44个化合物,包括16个黄酮类衍生物(1~16),15个酚酸类化合物(17~31),1个香豆素类化合物(32),2个木脂素类化合物(33~34),4个倍半萜(35~38),3个三萜类化合物(39~41),1个长链脂肪酸类化合物(42),2个甾体类化合物(43~44)。结论:其中化合物14,15,34,35为新化合物,分别命名为:isoetin-7-O-β-D-glucopyranosyl-2′-O-α-L-arabinopyranoside(14),isoetin-7-O-β-D-glucopyranosyl-2′-O-α-D-glucopyranoside(15),蒙古蒲公英素A(6,9,10-trihydroxy-benzoxanthene-1,2-dicarboxylic acid,mongolicuminA,34),蒙古蒲公英素B(11-hydroxy-2-oxo-guaia-1(10),3,5-trien-8,12-lactone,mongolicumin B,35);化合物1,3,6~13,20~22,30,31为首次从本属植物中分离得到,化合物18,23~29,32,37~42为首次从该种植物中分离得到。     

Phenolic compounds from the roots of Jordanian viper's grass, Scorzonera judaica

Nine new phenolic compounds, 3S-hydrangenol 40-O-R-L-rhamnopyranoysl-(1-->3)-β-D-glucopyranoside (1), thunberginol F 7-O-β-D-glucopyranoside (2), 2-hydroxy-6-[2-(4-hydroxyphenyl)-2-oxo-ethyl]benzoic acid (3), 2-hydroxy-6-[2-(3,4-dihydroxyphenyl)-2-oxo-ethyl]benzoic acid (4), 2-hydroxy-6-[2-(3,4-dihydroxyphenyl-5-methoxy)-2-oxoethyl]benzoic acid (5), hydrangeic acid 40-O-β-D-glucopyranoside (6), E-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)dihydrofuran-2-one (7), Z-3-(3,4-dihydroxybenzylidene)-5-(3,4-dihydroxyphenyl)-2(3H)-furanone (8), and 4-[β-D-glucopyranosyl)hydroxy]-pinoresinol (9), and nine known compounds were isolated from the roots of Scorzonera judaica. Structures of 1-9 were elucidated by mass spectrometry, extensive 1D and 2D NMR spectroscopy, and CD spectroscopy.All compounds were evaluated for cytotoxic activity.     

秋鼠曲草化学成分研究

目的:研究鼠曲草属植物秋鼠曲草的化学成分。方法:利用硅胶柱色谱、ODS反相柱色谱、Sephadex LH-20等手段进行分离纯化,根据理化性质和波谱数据进行结构鉴定。结果:从秋鼠曲草中分离得到10个化合物,分别鉴定为:二十四烷酸(1)、5-羟基-3,6,7,8-四甲氧基黄酮(2)、β-谷甾醇(3)、5-羟基-3,6,7,8,4'-五甲氧基黄酮(4)、5-羟基-3,6,7,8,3',4'-六甲氧基黄酮(5)、芹菜素(6)、木犀草素(7)、槲皮素(8)、木犀草素-4'-O-β-D-葡萄糖苷(9)、槲皮素-4'-O-β-D-葡萄糖苷(10)。结论:以上化合物均为首次从该植物中分离得到,化合物5为首次从该属植物中分离得到。     

藏药脉花党参的化学成分(英文)

目的:研究藏药脉花党参 Codonopsis nervosa ( Chipp.) Nannf.地上部分的化学成分。方法:采用 D101 大孔树脂柱、硅胶柱、ODS 柱、凝胶柱等色谱手段进行化学分离和纯化, 并利用各种波谱技术进行结构鉴定。结果:分离并鉴定了 15 个化合物, 分别为柯伊利素(1), 苜蓿素(2), 芹菜素(3), 琥珀酸(4), β-胡萝卜苷(5), 木犀草素(6), 木犀草素-7-O-β-D-葡萄糖苷(7),ethylsyringin (8), 芹菜素-7-O-β-D-葡萄糖苷(9), 木犀草素-7-O-β-D-葡萄糖基-(1→6)-[(6’’’-O-咖啡酸)-β-D-葡萄糖苷](10), 木犀草素-7-O-β-D-龙胆二糖苷(11), 丁香苷(12), 绿原酸(13), 新绿原酸(14), 对羟基苯甲酸葡萄糖苷(15)。结论:化合物 1 5, 8, 9, 12, 14,15 均首次从该植物中分离得到。