超短波并音频电中药离子导入综合治疗慢性盆腔炎128例

目的:观察超短波并音频电中药离子导入综合治疗慢性盆腔炎的临床疗效。方法:256例确定为慢性盆腔炎的门诊患者双盲随机分为超短波并音频电治疗对照组a组128例,超短波并音频电中药离子导入综合治疗组b组128例。结果:临床治愈率a组35.94%,b组55.47%,总有效率a组89.84%,b组97.66%,两组间有非常显著的差异性,P<0.01。结论:超短波并音频电中药离子导入综合治疗慢性盆腔炎的疗效优于超短波并音频电治疗组。     

超短波并直流电药物离子导入配合药物综合治疗慢性盆腔炎100例观察

目的:观察超短波并直流电药物离子导入综合治疗慢性盆腔炎的疗效。方法:100例慢性盆腔炎患者随机分为治疗组和对照组,药物常规治疗后,对照组用超短波治疗,治疗组用超短波并碘离子导入综合治疗,治疗3个疗程后观察效果。结果:治疗组疗效明显优于对照组,差异非常显著(P<0.01)。结论:超短波并碘离子导入综合治疗慢性盆腔炎疗效优于单纯超短波治疗。     

超短波周波治疗乳腺增生病临床研究

目的 为了提高乳腺增生病的疗效,保证生存质量.方法 选择我院2000年1月-2005年4月就诊患者108例,分为2组58例采用超短波周波治疗,对照组50例单纯采用超短波治疗;观察2组疗效.结果 观察组治愈21例,显效30例,好转2例,无效2例.总有效率97%.对照组治愈10例,显效10例,好转12例,无效18例,总有效率64%.2组总有效率比较有非常显著性差异(P<0.001).结论 超短波周波是目前治疗乳腺增生病的有效方法,值得临床研究.     

慢性盆腔炎综合治疗80例临床观察

目的：探讨综合方法治疗慢性盆腔炎的临床效果。方法：将2009年8月～2012年10月来我院治疗的160例慢性盆腔炎患者随机分为两组。观察组（综合治疗组）80例,用抗菌药物＋中药＋微波联合;对照组（单纯药物治疗组）80例,联合两种以上抗菌药物＋糜蛋白酶。比较两组疗效。结果：观察组治愈67例,好转13例,总有效率100%;对照组治愈53例,好转12例,总有效率81.3%。观察组总有效率明显高于对照组（χ2=16.55,P〈0.01）。结论：综合治疗慢性盆腔炎疗效确切,治愈率高,无不良反应,值得临床推广。     

192例慢性盆腔炎患者中医治疗的护理

目的:观察中药保留灌肠联合电脑中频药物导入并配合护理治疗慢性盆腔炎的疗效.方法:将慢性盆腔炎患者192例,随机分为两组,治疗组96例,用中药保留灌肠联合电脑中频药物导入治疗;对照组96例,用中药保留灌肠.结果:总有效率治疗组为96.88%,对照组为84.38%(P<0.01).结论:应用中药保留灌肠联合电脑中频药物导入治疗慢性盆腔炎,总治愈率达97%,并通过精心的护理和严密观察,疗效确切,治疗安全.     

中西医联合治疗慢性盆腔炎53例临床分析

目的观察中药灌肠联合超短波和西药治疗慢性盆腔炎的临床疗效。方法以我院2007年1月-2008年6月住院患者53例为治疗组,同期在门诊就诊不住院的55例患者为对照组。结果治疗组治愈率56.6%,总有效率90.6%,对照组治愈率36.4%,总有效率76.。4%结论中药灌肠联合超短波和西药治疗慢性盆腔炎的作用显著,值得临床推广。     

电泳导入法在慢性盆腔炎中的应用研究

目的探讨电泳导入法治疗慢性盆腔炎的临床疗效。方法将80例慢性盆腔炎患者随机分为治疗组和对照组各40例。对照组常规静滴抗生素治疗,治疗组则在对照组的基础上,中药煎剂灌肠后,应用单向中频脉冲电流将药物透入患者盆腔,治疗2个疗程后观察并判断疗效。结果治疗组治愈率52.5%,总有效率97.5%,对照组治愈率17.5%,总有效率77.5%,两组比较,治愈率和总有效率差异均有统计学意义(P<0.01)。结论电泳导入法治疗慢性盆腔炎疗效显著,值得临床使用。     

综合物理治疗腰椎间盘突出症的临床意义

目的探讨物理综合治疗腰椎间盘突出症的临床效果。方法将120例腰椎间盘突出症患者随机分成两组,其中对照组58例,单纯用牵引治疗;治疗组62例,在牵引治疗的基础上加用超短波、电脑中频、醋离子导入和相关的健康教育等综合康复治疗。结果治疗组治愈42例,显效11例,好转7例,无效2例,总有效率为96.77%,对照组治愈25例,显效10例,好转5例,无效8例,总有效率为86.21%,两组比较差异有显著性(P<0.05)。结论综合物理治疗对腰椎间盘突出症有较高的康复价值,能提高和巩固疗效。     

康妇消炎栓联合微波治疗慢性盆腔炎疗效观察

目的探讨康妇消炎栓联合微波治疗慢性盆腔炎的临床效果。方法将118例慢性盆腔炎患者按入院先后随机分为观察组与对照组各59例,观察组给予康妇消炎栓联合微波治疗,对照组给予单纯康妇消炎栓治疗,比较两组的有效率及复发率等临床指标。结果观察组治愈22例,显效33例,好转2例,无效2例,总有效率97.0%,复发5例（8.4%）;对照组治愈11例,显效13例,好转14例,无效21例,总有效率64.0%,复发12例（20.3%）。组间总有效率及复发率比较差异有显著性（P〈0.05）。结论微波联合康妇消炎栓是目前治疗慢性盆腔炎的有效方法,值得临床推广应用。     

针灸联合超短波治疗慢性盆腔炎140例观察

目的观察针灸联合超短波治疗慢性盆腔炎的疗效。方法将140例慢性盆腔炎患者随机分为2组,治疗组给予针灸＋超短波治疗,对照组采用西医常规疗法。结果在治疗组中,治愈率和总有效率分别为68.57%和97.14%,明显高于对照组的34.29%和87.14%,其差异有统计学意义（P〈0.05）。在治疗组中,1、2、3疗程有效率分别为74.29%、92.86%、97.14%,明显高于对照组的58.57%、78.57%、87.14%,其差异有统计学意义（P〈0.05）。结论针灸联合超短波综合治疗慢性盆腔炎有较好的疗效,值得临床推广应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.