Hyperbaric oxygen therapy as a method of treatment of laryngeal and pharyngeal radionecrosis

The authors described two cases of palatine tonsil carcinoma treated with surgery and subsequent radiation therapy after which occurred severe radionecrosis of the larynx, pharynx and oral cavity. These subjects were treated with hyperbaric oxygen therapy (HBO). Complete resolution of postradiation changes was observed. The authors described: 1) basic changes in the tissues caused by radiation therapy; 2) the mechanisms of healing activity of hyperbaric oxygen.     

Anticoagulant therapy induced haematoma presenting as acute dysphagia

Oropharyngeal haematoma secondary to bleeding from anticoagulant therapy is uncommon and difficult to manage. We report a case of Oropharyngeal haematoma secondary to anticoagulant Acitrom (Nicoumalone) which was treated successfully with Inj Vit K.     

Atypical presentation of laryngeal tuberculosis in a pediatric patient

Laryngeal tuberculosis is uncommon and most often associated with a primary lung infection in immunocompromised adults. We describe an atypical case in a pediatric patient with a relatively rapid onset and no history of travel or exposure to high-risk settings. Despite the unusual presentation and relative lack of familiarity with procedural guidelines in managing this uncommon and capricious disease by otolaryngologists in developed countries, reporting is mandated at multiple governmental health department levels. Consequently, this contagious entity must be considered in the interest of avoiding untoward outcomes for not only the patient, but the public as well.     

Simple method to control laryngeal overspill in tracheostomized patients

An inflatable balloon was inserted through a pre-existing tracheostomy to occlude the upper trachea. This technique controlled previously intractable laryngeal overspill for a period of three months in a patient with inoperable carcinoma of the larynx.     

Diagnosis of laryngeal tuberculosis in a high TB burden area

European Archives of Oto-Rhino-Laryngology - The larynx is the second most commonly affected site in the head and neck region in patients with extrapulmonary tuberculosis (TB). Despite this, the...     

The presentation of laryngeal tuberculosis

Laryngeal tuberculosis is now a rare disease. We report 6 patients presenting within a 10-year period (1976-1986). Symptoms and signs often mimic carcinoma or chronic non-specific laryngitis. Greater clinical awareness and a chest radiograph prior to direct laryngoscopy may alert the clinician to the possibility of tuberculosis. The diagnosis is established by laryngeal biopsy.     

On aspects of laryngeal tuberculosis

In 1989-1998 the authors treated 50 patients (45 males and 5 females aged 21-68 years, mean age 46.2 years) with tuberculosis of the lungs and larynx. Pulmonary lesions were for the most part disseminated (58%) or infiltrative (24%). One patient had laryngeal tuberculosis combination with cancer of the laryngeal pharynx. Progression of the disease occurs frequently because of otorhinolaryngologists who make diagnostic errors when consulting patients who seek primarily their advice (60% of those with laryngeal tuberculosis) complaining about throat pain and hoarseness. In obscure cases, an attempt of antituberculosis treatment should be made.     

Current aspects of laryngeal tuberculosis

In the preantibiotic era laryngeal tuberculosis was the most frequent pathology of the larynx. In the last decades some changes in the presentation and evolution of the pathology have occurred due to the new chemiotherapy and the improvement of the nutrition. Actually it presents less incidence and infectivity and less evidence of pulmonary disease. In this article we analyse, on occasion of a clinical case and with a revision of the literature, the actual patterns of the laryngeal tuberculosis.     

Rare case of laryngeal tuberculosis

In this work was described one case tuberculosis of the larynx. Provisional diagnosis was tumor of the larynx, because of similar symptoms. Authors described diagnostic and treatment which should be carry out in the similar cases.     

Validation of laser Doppler fluxmetry as a method of assessing neo-angiogenesis in laryngeal tumours

Our intention was to validate the hypothesis that laser Doppler fluxmetry would give a valid representation of underlying tissue blood flow and would provide a reliable tool for measuring blood flow in human laryngeal cancers. This was an experimental prospective study. We performed laser Doppler fluxmetry on 20 patients with laryngeal cancer and compared the values obtained through this method with manual counting of microvessel density from biopsies, the accepted gold standard. We demonstrated good inter- and intraobserver variability in our estimation of microvessel density. We then compared microvessel density with laser Doppler fluxmetry, and using Spearmans test to assess nonparametric correlation, we obtained a correlation coefficient of 0.4 ( P value: 0.15). To our knowledge, this study is the first of its kind to demonstrate a positive trend between angiogenesis measured conventionally when compared with laser Doppler fluxmetry.