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1.
Goldberg WA Jarvis KL Osann K Laulhere TM Straub C Thomas E Filipek P Spence MA 《Journal of autism and developmental disorders》2005,35(5):657-664
The early social and communicative development of very young siblings of children with autism spectrum disorder (ASD) is the
focus of the current study. Three groups of children were included: (1) young children diagnosed with ASD, (2) younger siblings
in families with a somewhat older child with ASD, and (3) young typically developing children. All children participated in
a videotaped, structured interactional procedure called the Early Social Communication Scales (ESCS; [Mundy & Hogan, 1996,
A Preliminary Manual for the Abridged Early Social Communication Scales (ESCS) Unpublished manual, University of Miami]).
Very young siblings were compared to young children with a diagnosed autism spectrum disorder and to a group of young typically
developing children. Results indicated that, on three of four of the ESCS subscales, the social communicative behaviors of
the younger siblings differed from those of the typically developing children but not from the behaviors displayed by the
ASD group. Genetic vulnerability for ASD among siblings and characteristics of family interaction may explain the level of
impairment observed in the very young siblings of children with autism spectrum disorders. 相似文献
2.
3.
Gadow KD Devincent C Schneider J 《Journal of autism and developmental disorders》2008,38(9):1710-1720
This study examined mental health risk/protective factors for DSM-IV psychiatric symptoms in children with an autism spectrum
disorder (ASD) and their contribution to functioning separate from ASD symptom severity. Mothers/teachers completed measures
of risk/protection and social, adaptive, and school functioning in 6- to 12-year-olds with a diagnosed ASD (N = 238). Bivariate correlations and simultaneous regression analyses indicated a unique pattern of predictors for attention-deficit/hyperactivity
disorder, aggression, anxiety, and depression symptoms. Moreover, psychiatric symptoms differentially predicted social and
school performance. Findings indicate that co-occurring psychiatric symptoms and their associated mental health risk/protective
factors may have important clinical implications and generally support a biopsychosocial model of psychopathology in children
with an ASD that appears to share many similarities with models for nonASD children. 相似文献
4.
In this study we examined early motor, vocal, and communicative development in a group of younger siblings of children diagnosed
with autism (Infant Siblings). Infant Siblings and no-risk comparison later-born infants were videotaped at home with a primary
caregiver each month from 5 to 14 months, with follow-up at 18 months. As a group, Infant Siblings were delayed in the onset
of early developmental milestones and spent significantly less time in a greater number of postures, suggestive of relative
postural instability. In addition, they demonstrated attenuated patterns of change in rhythmic arm activity around the time
of reduplicated babble onset; and they were highly likely to exhibit delayed language development at 18 months. 相似文献
5.
Annette Estes Jeffrey Munson Tanya St. John Stephen R. Dager Amy Rodda Kelly Botteron Heather Hazlett Robert T. Schultz Lonnie Zwaigenbaum Joseph Piven Michael J. Guralnick the IBIS network 《Journal of autism and developmental disorders》2018,48(4):1122-1132
Preschool-aged siblings of children with ASD are at high-risk (HR) for ASD and related challenges, but little is known about their emerging peer competence and friendships. Parents are the main providers of peer-relationship opportunities during preschool. Understanding parental challenges supporting early peer relationships is needed for optimal peer competence and friendships in children with ASD. We describe differences in peer relationships among three groups of preschool-aged children (15 HR-ASD, 53 HR-NonASD, 40 low-risk, LR), and examine parent support activities at home and arranging community-based peer activities. Children with ASD demonstrated precursors to poor peer competence and friendship outcomes. Parents in the HR group showed resilience in many areas, but providing peer opportunities for preschool-age children with ASD demanded significant adaptations. 相似文献
6.
Paul Yoder Wendy L. Stone Tedra Walden Elizabeth Malesa 《Journal of autism and developmental disorders》2009,39(10):1381-1391
Later-born siblings of children with autism spectrum disorder (Sibs-ASD) are at elevated risk for social impairments. Two
putative predictors of later social impairment—measures of responding to joint attention and weighted triadic communication—were
examined in a sample of 43 Sibs-ASD who were followed from 15 to 34 months of age. Results revealed that initial level of
responding to joint attention and growth rate of weighted triadic communication predicted the degree of social impairment
at the final measurement period. Additionally, both predictors were associated with later ASD diagnosis. In contrast, unweighted
triadic communication, age of entry into the study, and initial language level did not predict later social impairment. The
importance of considering social outcome as a continuous variable in prospective studies of Sibs-ASD is discussed. 相似文献
7.
Shattuck PT Seltzer MM Greenberg JS Orsmond GI Bolt D Kring S Lounds J Lord C 《Journal of autism and developmental disorders》2007,37(9):1735-1747
This study examined change prospectively in autism symptoms and maladaptive behaviors during a 4.5 year period in 241 adolescents
and adults with an autism spectrum disorder who were 10–52 years old (mean = 22.0) when the study began. Although many individuals’
symptoms remained stable, a greater proportion of the sample experienced declines than increases in their level of autism
symptoms and maladaptive behaviors, and there were significant improvements in mean levels of symptoms. Individuals with mental
retardation had more autism symptoms and maladaptive behaviors than those without mental retardation, and they improved less
over time. Compared to adolescents, older sample members (31 and older) had fewer maladaptive behaviors and experienced more
improvement in these behaviors over time. 相似文献
8.
Molloy CA Dietrich KN Bhattacharya A 《Journal of autism and developmental disorders》2003,33(6):643-652
Maintaining upright posture is a complex process involving multiple afferent systems. The aim of this study was to measure the postural stability of children with Autism Spectrum Disorder (ASD) compared with children with typical neurodevelopment and to measure the relative contributions of the visual, somatosensory, and vestibular afferent systems in each group. Eight boys with ASD and eight age-, race-, and gender-matched controls participated in this study using force platform technology with customized software to measure postural sway under conditions designed to eliminate or modify visual and somatosensory input. Children with ASD had significantly larger sway areas under all test conditions in which afferent input was modified. These results are consistent with a deficit in the integration of visual, vestibular, and somatosensory input to maintain postural orientation. 相似文献
9.
Warren ZE Foss-Feig JH Malesa EE Lee EB Taylor JL Newsom CR Crittendon J Stone WL 《Journal of autism and developmental disorders》2012,42(3):409-418
Later-born siblings of children with Autism Spectrum Disorders (ASD) are at increased risk for ASD as well as qualitatively
similar traits not meeting clinical cutoffs for the disorder. This study examined age five neurocognitive and behavioral outcomes
of 39 younger siblings of children with ASD (Sibs-ASD) and 22 younger siblings of typically developing children (Sibs-TD)
previously assessed in a longitudinal investigation starting in the second year of life. There were few group differences
between Sibs-TD and Sibs-ASD on global measures of IQ, language, or behavior problems. Sibs-ASD did show vulnerabilities on
measures of executive functioning, social cognition, and repetitive behaviors. These results highlight the importance of following
sibling risk groups over an extended time period and employing measures targeting broader aspects of development. 相似文献
10.
Christ SE Holt DD White DA Green L 《Journal of autism and developmental disorders》2007,37(6):1155-1165
Impairments in executive abilities such as cognitive flexibility have been identified in individuals with autism spectrum disorder (ASD). It remains unclear, however, whether such individuals also experience impairments in another executive ability: inhibitory control. In the present study, we administered three inhibitory tasks to 18 children with ASD, 23 siblings of children with ASD, and 25 typically developing children. After controlling for individual differences in age, overall IQ, and processing speed, children with ASD demonstrated impaired performance on two of the three inhibitory tasks. Results suggest that children with ASD experience circumscribed deficits in some but not all aspects of inhibitory control. More generally, the findings underscore the importance of using multiple measures to assess a putative single cognitive ability. 相似文献
11.
Oppositional Defiant Disorder as a Clinical Phenotype in Children with Autism Spectrum Disorder 总被引:1,自引:1,他引:0
Gadow KD Devincent CJ Drabick DA 《Journal of autism and developmental disorders》2008,38(7):1302-1310
To examine the validity of oppositional defiant disorder (ODD) as a clinical phenotype distinct from attention-deficit hyperactivity disorder (ADHD), parents and teachers completed a DSM-IV-referenced rating scale and a background questionnaire for 608 children (ages 3-12 years) with autism spectrum disorder (ASD). The ASD sample was separated into four groups: ODD, ADHD, ODD + ADHD, and neither (NONE). Comparison samples were non-ASD clinic (n = 326) and community (n > 800) controls. In the ASD sample, all three ODD/ADHD groups were clearly differentiated from the NONE group, and the ODD + ADHD group had the most severe co-occurring symptoms, medication use, and environmental disadvantage. There were few differences between ASD + ODD and ASD + ADHD groups. Findings for ASD and control samples were similar, supporting overlapping mechanisms in the pathogenesis of ODD. 相似文献
12.
Jana M. Iverson Jessie B. Northrup Nina B. Leezenbaum Meaghan V. Parladé Erin A. Koterba Kelsey L. West 《Journal of autism and developmental disorders》2018,48(1):55-71
This study examined longitudinal growth in gestures and words in infants at heightened (HR) versus low risk (LR) for ASD. The MacArthur-Bates Communicative Development Inventory was administered monthly from 8 to 14 months and at 18 and 24 months to caregivers of 14 HR infants diagnosed with ASD (HR-ASD), 27 HR infants with language delay (HR-LD), 51 HR infants with no diagnosis (HR-ND), and 28 LR infants. Few differences were obtained between LR and HR-ND infants, but HR-LD and HR-ASD groups differed in initial skill levels and growth patterns. While HR-LD infants grew at rates comparable to LR and HR-ND infants, growth was attenuated in the HR-ASD group, with trajectories progressively diverging from all other groups. 相似文献
13.
The relationship between symbolic play and other domains, such as degree of autistic symptomatology, nonverbal cognitive ability,
receptive language, expressive language, and social development, was investigated. The assessment files of 101 children with
Autism Spectrum Disorder were studied. Nonverbal cognitive ability and expressive language were both significantly and uniquely
related to symbolic play, although receptive language was not. Autistic symptomatology ceased to be significantly related
to symbolic play when controlling for two or more other variables. Social development was related to symbolic play in those
children with high nonverbal cognitive ability but not those with low nonverbal cognitive ability. The diagnostic and treatment
implications of these results are discussed. 相似文献
14.
This study aimed to investigate temporally extended self-awareness (awareness of one’s place in and continued existence through
time) in autism spectrum disorder (ASD), using the delayed self-recognition (DSR) paradigm (Povinelli et al., Child Development
67:1540–1554, 1996). Relative to age and verbal ability matched comparison children, children with ASD showed unattenuated performance on the
DSR task, despite showing significant impairments in theory-of-mind task performance, and a reduced propensity to use personal
pronouns to refer to themselves. The results may indicate intact temporally extended self-awareness in ASD. However, it may
be that the DSR task is not an unambiguous measure of temporally extended self-awareness and it can be passed through strategies
which do not require the possession of a temporally extended self-concept.
相似文献
Sophie E. LindEmail: |
15.
Presmanes AG Walden TA Stone WL Yoder PJ 《Journal of autism and developmental disorders》2007,37(1):133-144
We compared responding to joint attention (RJA) in younger siblings of children with ASD (SIBS-ASD; n = 46) and younger siblings of children developing typically (SIBS-TD; n = 35). Children were tested between 12 and 23 months of age in a situation in which an experimenter directed the child’s
attention to one of 8 targets. Each child responded to 10 different combinations of verbal and nonverbal cues containing varying
levels of attention-specifying information. SIBS-ASD had significantly lower overall RJA scores than SIBS-TD. Moderately redundant
cues were most difficult for SIBS-ASD relative to SIBS-TD; adding a point to moderately redundant cues improved RJA for SIBS-ASD,
bringing them to a level of RJA commensurate with SIBS-TD. 相似文献
16.
Medical Expenditures for Children with an Autism Spectrum Disorder in a Privately Insured Population
This study provides estimates of medical expenditures for a subset of children and adolescents who receive employer-based health insurance and have a medical diagnosis of an autism spectrum disorder (ASD). Data analyzed were from the 2003 MarketScan research databases. Individuals with an ASD had average medical expenditures that exceeded those without an ASD by $4,110-$6,200 per year. On average, medical expenditures for individuals with an ASD were 4.1-6.2 times greater than for those without an ASD. Differences in median expenditures ranged from $2,240 to $3,360 per year with median expenditures 8.4-9.5 times greater. These findings add to a growing body of evidence that children and adolescents with medical diagnoses of an ASD incur elevated medical utilization and costs. 相似文献
17.
Nation K Clarke P Wright B Williams C 《Journal of autism and developmental disorders》2006,36(7):911-919
This study investigated reading skills in 41 children with autism spectrum disorder. Four components of reading skill were assessed: word recognition, nonword decoding, text reading accuracy and text comprehension. Overall, levels of word and nonword reading and text reading accuracy fell within average range although reading comprehension was impaired. However, there was considerable variability across the sample with performance on most tests ranging from floor to ceiling levels. Some children read accurately but showed very poor comprehension, consistent with a hyperlexia reading profile; some children were poor at reading words and nonwords whereas others were unable to decode nonwords, despite a reasonable level of word reading skill. These findings demonstrate the heterogeneous nature of reading skills in children with ASD. 相似文献
18.
Szatmari P Georgiades S Duku E Zwaigenbaum L Goldberg J Bennett T 《Journal of autism and developmental disorders》2008,38(10):1859-1865
Given the recent findings regarding the association between alexithymia and Autism Spectrum Disorder (ASD) and the accumulating
evidence for the presence of the Broader Autism Phenotype (BAP) in relatives of individuals with ASD, we further explored
the construct of alexithymia in parents of children with ASD as a potential part of the BAP. We hypothesized that (a) parents
of children with ASD will demonstrate higher impairment in their emotion processing when compared to controls, and (b) high
impairment in emotion processing in parents will be associated with severity of symptoms in children with ASD. Psychometric
and diagnostic data were collected on 188 children with a diagnosis of ASD. The Toronto Alexithymia Scale (TAS-20) was completed
by 439 parents of children with ASD and a control group of 45 parents of children with Prader Willi syndrome (PW). Results
show that ASD parents score higher than controls on the TAS-20 total score. Within the ASD group, children of fathers with
high alexithymia score higher on repetitive behaviour symptoms compared to children of fathers with low alexithymia. The alexithymia trait appears to be one of the many building blocks that make up the BAP. 相似文献
19.
Gael I. Orsmond Marsha Mailick Seltzer 《Journal of autism and developmental disorders》2009,39(7):1053-1065
The purpose of this study was to test a diathesis-stress model of well-being for siblings who have a brother or sister with
an autism spectrum disorder (ASD). Data were collected from 57 adolescents and their mothers. Sisters reported higher levels
of depressive and anxiety symptoms than brothers. Having a family history of ASDs was associated with depressive, but not
anxiety, symptoms. A high level of maternal depression was also associated with more depressive and anxiety symptoms. A diathesis-stress
model was partially supported, primarily through the findings that sibling sub-threshold autism characteristics were associated
with depressive and anxiety symptoms in siblings, but only in the presence of a high number of stressful life events. 相似文献
20.
Boger-Megiddo I Shaw DW Friedman SD Sparks BF Artru AA Giedd JN Dawson G Dager SR 《Journal of autism and developmental disorders》2006,36(6):733-739
This study assessed midsagittal corpus callosum cross sectional areas in 3–4 year olds with autism spectrum disorder (ASD) compared to typically developing (TD) and developmentally delayed (DD) children. Though not different in absolute size compared to TD, ASD callosums were disproportionately small adjusted for increased ASD cerebral volume. ASD clinical subgroup analysis revealed greater proportional callosum reduction in the more severely affected autistic disorder (AD) than in pervasive developmental disorder-not otherwise specified (PDD-NOS) children. DD children had smaller absolute callosums than ASD and TD. Subregion analysis revealed widely distributed callosum differences between ASD and TD children. Results could reflect decreased inter-hemispheric connectivity or cerebral enlargement due to increase in tissues less represented in the corpus callosum in ASD. 相似文献