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Squamous cell carcinoma (SCC) is the most common malignancy arising in the oral cavity. It can cause severe morbidity and mortality due to its propensity to metastasis. Despite the likelihood of distant metastases, commonly to the lungs, there is little report in the literature of metastatic spread to the spinal vertebrae from oral SCC with secondary spinal cord compression. We report 2 patients with advanced SCC in the tongue who developed signs of spinal cord compression due to metastasis to lumbar vertebrae. The clinical impression of metastasis causing spinal cord compression was confirmed by magnetic resonance imaging.  相似文献   

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口腔鳞癌中p12蛋白的表达   总被引:1,自引:0,他引:1  
目的:探讨p12蛋白在口腔鳞状细胞癌组织中的表达及其与口腔鳞癌发生发展的关系。方法:采用免疫组织化学S-P法,对40例口腔鳞癌组织,4例重度异常增生,8例口腔粘膜溃疡,6例口腔正常粘膜组织中p12蛋白的表达情况进行检测。结果:口腔鳞癌及重度异常增生组织中p12蛋白的表达明显低于炎性病变及正常粘膜组织。结论:p12蛋白在口腔鳞状细胞癌组织中的表达常为缺失,说明其作为一种候选抑癌基因在口腔鳞癌的发生中可能起一定作用,且不存在组织部位特异性。  相似文献   

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Background  

Lymph node density (LND) is superior to TNM nodal status in predicting survival after surgery for bladder and other cancers. Little is known, however, about whether LND can predict survival in patients with oral squamous cell carcinoma (OSCC). We therefore evaluated the utility of LND for predicting survival for patients with OSCC and positive nodes (pN+).  相似文献   

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