The artificial iris – Analysis of various implantation techniques after ocular trauma

Purpose:The aim of this study is to analyze the outcome of various techniques for a custom-made iris prosthesis implantation as part of reconstructive anterior segment surgery following traumatic aniridia.Methods:This retrospective interventional study was done for 6 eyes that received an artificial iris as secondary reconstructive measure for photophobia and unsatisfactory vision following initial globe repair. Different implantation techniques were employed. These included simple sulcus implantation, implantation of a composite (iris prosthesis with attached intraocular lens) implant, and combinations with phacoemulsification, vitrectomy, and penetrating keratoplasty.Results:In all cases, the artificial iris was implanted successfully. In the follow-up period (1–48 months), postoperative complications included rhegmatogenous retinal detachment, prolonged intraocular inflammation, and corneal transplant decompensation due to graft rejection. There was no case of secondary glaucoma. Complications could be managed successfully. All patients showed improved best-corrected visual acuity and were satisfied with functional and cosmetic results.Conclusion:This case series highlights the different implantation techniques for reconstruction of the anterior segment after ocular trauma. The versatility of the custom-made iris implant accounts for a wide range of applications and the foldable material reduces the need for large incisions in the already traumatized eye.     

Outcomes of prosthetic iris implantation in patients with albinism

PURPOSE: To assess the safety and efficacy of implantation of prosthetic iris devices in patients with albinism. SETTING: Private practice, Cincinnati, Ohio, USA. METHODS: This retrospective noncomparative case series comprised 13 eyes of 8 patients with diminished pigment epithelium of the iris secondary to albinism. All eyes had anterior segment surgery with intraocular lens (IOL) and prosthetic iris device implantation. Eleven eyes received an endocapsular-type iris reconstruction implant (Morcher aniridia interdigitating rings), and 2 eyes (1 patient) received a combined iris-IOL device (Ophtec model 311). The visual acuity, subjective glare reduction, postoperative anatomical outcomes, and intraoperative or postoperative complications were reviewed. RESULTS: All eyes achieved the desired anatomic result. The best corrected visual acuity improved in 8 of 13 eyes, remained stable in 3 eyes, and decreased in 2 eyes. Glare and photophobia improved subjectively in 6 of 8 patients, remained unchanged in 1 patient, and increased in 1 patient after implantation of an artificial iris diaphragm. There were no intraoperative or postoperative complications. CONCLUSIONS: Implantation of prosthetic iris devices appears to be useful in the management of patients with iris deficiency secondary to albinism. The procedure was safe and particularly effective in reducing glare and photophobia in most patients.     

飞秒激光辅助的穿透性角膜移植联合手法碎核白内障摘除人工晶状体植入术

目的：探讨同时行飞秒激光辅助的穿透性角膜移植术（ PKP）及小切口手法碎核白内障摘除联合人工晶状体植入术治疗同时患有白内障及角膜病患者的适应证、手术技巧及术后疗效。方法应用飞秒激光辅助的PKP联合小切口手法碎核白内障摘除人工晶状体植入术治疗同时患有白内障及角膜病的患者6例（6只眼）,观察其术后裸眼视力、最佳矫正视力、眼压、植片、人工晶状体情况及前房反应。随访9个月。结果治疗后6例术后裸眼视力均比术前有不同程度的提高,术后9个月裸眼视力≥0．3者4例,0．2者2例;5例最佳矫正视力≥0．5,1例最佳矫正视力为0．4。术后7～14 d,5例角膜植片全透明,1例角膜植片轻度水肿。至术后9个月,6例角膜植片全透明;6例术后眼压均正常,人工晶状体位置正,位于囊袋内。结论飞秒激光辅助的PKP联合小切口手法碎核白内障摘除人工晶状体植入术对眼球损伤更小、手术效果更确切、治疗病程更短,可以一次性解决眼前段的屈光间质混浊。与传统分期手术相比减少了术后并发症,使患者快速恢复术后视力,安全性较高。     

【In Press】Complications and outcomes of descemet stripping automated endothelial keratoplasty with Artisan aphakia intraocular lens implantation

AIM: To evaluate the complications and outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) combined with Artisan aphakia intraocular lens (IOL) implantation in severely damaged eyes without capsular support. METHODS: DSAEK combined with Artisan iris claw IOL implantation was performed on 29 eyes. All eyes were of abnormal structure due to complications from prior intraocular surgeries and ocular trauma. Ocular complications observed included graft dislocations, high intraocular pressure (IOP), IOL dislocations, macular edema, and hyphema. Best-corrected visual acuity (BCVA), IOP, and mean central endothelial cell density (ECD) were recorded. RESULTS: Thirteen eyes had a history of ocular trauma, 10 eyes had an anterior chamber IOL, and 16 eyes had prior vitrectomy. The iris was abnormal in 22 cases. Graft dislocation occurred in 5 (17%) of 29 eyes. IOL dislocation occurred in 2 eyes (6.9%). High IOP was found in 9 eyes and was controlled with treatment. The preoperative mean BCVA was 20/286. The 6mo postoperative mean BCVA was 20/42. The average center ECD was 1965.3 cells/mm2 at 6mo, and the rate of the donor cell loss was 34.7%. CONCLUSION: DSAEK combined with Artisan aphakia intraocular lens implantation is an alternative option for resolving endothelial and lens disorders in aphakic eyes without capsular support. However, it should be performed cautiously for eyes with severe iris defects.     

Complications and outcomes of descemet stripping automated endothelial keratoplasty with artisan aphakia intraocular lens implantation

AIM: To evaluate the complications and outcomes of descemet stripping automated endothelial keratoplasty (DSAEK) combined with artisan aphakia intraocular lens (IOL) implantation in severely damaged eyes without capsular support. METHODS: DSAEK combined with artisan iris claw IOL implantation was performed on 29 eyes. All eyes were of abnormal structure due to complications from prior intraocular surgeries and ocular trauma. Ocular complications observed included graft dislocations, high intraocular pressure (IOP), IOL dislocations, macular edema and hyphema. Best corrected visual acuity (BCVA), IOP and mean central endothelial cell density (ECD) were recorded. RESULTS: Thirteen eyes had a history of ocular trauma, 10 eyes had an anterior chamber IOL, 16 eyes had prior vitrectomy. The iris was abnormal in 22 cases. Graft dislocation occurred in 5 (17.2%) of 29 eyes. IOL dislocation occurred in 2 eyes (6.9%). High IOP was found in 9 eyes and was controlled with treatment. The preoperative mean BCVA was 20/286. The 6mo postoperative mean BCVA was 20/42. The average center ECD was 1965.3 cells/mm2 at 6mo, and the rate of the donor cell loss was 34.7%. CONCLUSION: DSAEK combined with artisan aphakia IOL implantation is an alternative option for resolving endothelial and lens disorders in aphakic eyes without capsular support. However, it should be performed cautiously for eyes with severe iris defects.     

Artisan aphakic intraocular lens in children with subluxated crystalline lenses

PURPOSE: To evaluate the results of Artisan (Ophtec) aphakic intraocular lens (IOL) implantation in children with idiopathic subluxated lenses. SETTING: Department of Ophthalmology, Soroka University Medical Center, Beer-Sheva, Israel. METHODS: This retrospective small case series comprised 4 eyes (3 children) with idiopathic essential subluxated lenses that had lens washout, lens capsule removal, Artisan IOL implantation, and peripheral iridectomy. The indications for surgery were reduced visual acuity and monocular diplopia. The main outcome measures were postoperative refraction and change in best corrected visual acuity (BCVA). RESULTS: The postoperative follow-up ranged from 8 to 10 months. After surgery, the BCVA was 6/12 or better in the 3 cases that could be recorded. Visual acuity improved by 2 or more Snellen lines in all 4 eyes. The postoperative spherical equivalent was within +/-1.00 diopter in all cases. No significant postoperative complications were observed. CONCLUSIONS: In 4 eyes with a subluxated crystalline lens, implantation of an Artisan aphakic IOL improved visual acuity. Studies with a larger number of patients and longer follow-up are necessary to confirm these results.     

Artisan虹膜夹持型人工晶状体植入术及后房型人工晶状体睫状沟缝线固定术治疗无晶状体眼的比较

目的:比较Artisan虹膜夹持型人工晶状体植入术及后房型人工晶状体睫状沟缝线固定术治疗无晶状体眼的疗效及并发症。方法:2007-03/2009-03我院住院患者中连续24例24眼无后囊膜支持的无晶状体眼患者,随机分为两组。一组11眼行Artisan虹膜夹持型人工晶状体植入术,另一组13眼选择后房型人工晶状体睫状沟缝线固定术。观察手术前及手术后1d;1wk;1mo的裸眼视力(visual acuity,VA)、最佳矫正视力(best corrected visual acuity,BCVA)、眼压(intraocularpressure,IOP)、角膜内皮细胞计数(corneal endothelial cells,CECs)。结果:两组间比较,术前VA,BCVA,CECs差异无统计学意义,术后BCVA,CECs差异无统计学意义。Artisan组手术后VA优于术前BCVA,差异有统计学意义。睫状沟缝线固定组手术后VA与手术前BCVA差异无统计学意义。两组手术前后IOP差异无统计学意义。结论:Artisan虹膜夹持型人工晶状体植入术与后房型人工晶状体睫状沟缝线固定术都是治疗无晶状体眼有效方法。两者比较,Artisan虹膜夹持型人工晶状体植入术手术操作相对简单,组织损伤小,更加安全,是治疗无后囊膜支持的无晶状体眼的比较理想的治疗方法。     

辅助技术在治疗白内障合并角膜混浊手术中的应用

目的：评价在白内障手术中应用包括囊膜染色、虹膜拉钩、虹膜切除等辅助技术治疗白内障合并角膜混浊患眼的术后视觉效果,并分析手术安全性和有效性。

方法：回顾收集2014-01/2019-03在新疆军区总医院全军眼科中心接受白内障超声乳化合并人工晶状体植入术的白内障合并角膜混浊患者105例105眼,所有患者接受白内障超声乳化摘除并人工晶状体植入术。术中应用台盼蓝囊膜染色剂,并观察前囊膜染色情况,连续环形撕囊成功率,晶状体后囊破裂及人工晶状体囊袋内植入情况。并于术后1d,1wk,1、3mo对患者进行随访,观察术中撕囊成功率,术前、术后的最佳矫正视力(BCVA,LogMAR),术后并发症等。

结果：患者均接受白内障超声乳化吸除合并人工晶状体植入术。术中通过应用台盼蓝囊膜染色剂(台盼蓝)染色前囊膜辅助成功完成所有连续环形撕囊,并采取了包括应用虹膜拉钩及虹膜切开术等其他措施。将可折叠式人工晶状体植入105眼。术后追踪观察3mo,术眼术后BCVA为0.82±0.10,与术前BCVA(3.12±0.14)比较有差异(t=174.893,P<0.01)。

结论：白内障超声乳化摘除术能使白内障合并角膜混浊患者的视力得到安全有效的提高。辅助技术如囊膜染色、虹膜拉钩、虹膜切除等的应用,能有效降低白内障合并角膜混浊患者的白内障手术风险,提高手术安全性,增加手术成功率。     

角膜穿孔伤并白内障人工晶状体植入临床观察

目的探讨角膜穿孔伤合并外伤性白内障患者，人工晶状体植入联合手术方法及效果。方法对32例（32眼）角膜穿孔伤合并外伤性白内障施行的囊外摘出联合人工晶状体植入术进行回顾性分析。13眼采用Ⅰ期角膜缝合联合白内障囊外摘出联合人工晶状体植入术。19眼采用Ⅱ期白内障囊外摘出联合人工晶状体植入术。结果术后随访1-3月，视力≥1．0者4眼，占12．50％；0．5-0．9者19眼，占59．38％；0．1-0．4者6眼，占18．75％；0．1以下者3眼，占9．38％。结论角膜缝合，晶状体摘出和人工晶状体植入三联合手术的手术时机及术式的选择非常重要，同时须对术中、术后并发症采取合理的治疗措施。     

带虹膜隔人工晶状体植入术治疗白内障合并虹膜缺损的疗效观察

目的　评价带虹膜隔人工晶状体植入术治疗白内障合并虹膜缺损的疗效 ,探讨术后并发症的发生机制。方法　收集 2 5例 (2 7只眼 )行带虹膜隔人工晶状体植入术患者 ,分析手术疗效和并发症的发生情况 ,同时应用房角镜和超声生物显微镜 (UBM)观察术后发生继发性青光眼患者的房角结构和人工晶状体襻位置。术后随访时间 3～ 18个月。结果　术后患者畏光症状明显减轻或完全消失 ;术后视力较术前提高≥ 2行 2 0只眼 (74 1% ) ,变化 <1行 5只眼 (18 5 % ) ,下降 >2行 2只眼(7 4 % )。术后并发症包括继发性青光眼 10只眼 (37 0 % )、散光度数≥ 2 0 0D 17只眼 (6 3 0 % )、角膜失代偿 2只眼 (7 4 % )、前房出血 2只眼 (7 4 % )、玻璃体出血 3只眼 (11 1% )、视网膜脱离 1只眼(3 7% )。在继发性青光眼 10只眼 2 0只人工晶状体襻中 ,9只襻准确固定在睫状沟内 ,其他位置包括前房角、睫状突及睫状突后。房角改变包括房角后退、残留虹膜根部前粘连、房角关闭。结论　带虹膜隔人工晶状体植入术可有效治疗白内障合并虹膜缺损 ;术后继发性青光眼主要与房角损伤有关 ,人工晶状体襻位置异常、眼内出血、持续性炎性反应也参与其发生。     

Traumatic pediatric cataract: A decade of follow-up after Artisan aphakia intraocular lens implantation

PURPOSE: To describe the long-term clinical outcome of Artisan((R)) aphakia intraocular lens (IOL; Ophtec, Groningen, The Netherlands) implantation in five aphakic eyes of five children, without capsular support, after cataract extraction following penetrating ocular trauma. METHODS: The charts of the five children were retrospectively reviewed. The data collected included follow-up time, nature of injury, age at cataract extraction and IOL implantation, visual outcome, endothelial cell counts, complications, and subsequent surgical interventions. RESULTS: Average follow-up was 11.0 years (range, 8.0-14.6 years). All eyes had a corneal perforation with various degrees of anterior segment injury. Mean patient age at lens extraction was 7.8 years (range, 5.6-10.2 years). Mean age at Artisan aphakia IOL implantation was 7.9 years (range, 5.7-10.2 years). The best spectacle-corrected visual acuity at last follow-up was 20/40 or better in four eyes. Mean endothelial cell loss compared with the healthy fellow eye was 40%. No patients experienced IOL dislocation, corneal decompensation, chronic anterior uveitis, cystoid macular edema, or iris atrophy. One eye had a retinal detachment 19 months after primary injury and needed vitreoretinal surgery. CONCLUSIONS: The Artisan aphakia IOL offers a useful alternative for correction of traumatic childhood aphakia. Although we only have results of a small number of patients, taking into account our long follow-up period, we feel that implantation of the Artisan aphakia IOL can be considered a treatment option in aphakic eyes of children that lack capsular support due to trauma.     

Surgical management of iris defects with prosthetic iris devices

PURPOSE: To evaluate the safety and efficacy of surgical implantation of prosthetic iris devices in patients with iris deficiency. METHODS: Nine patients with traumatic iris defects, congenital aniridia or iris coloboma, and surgical or optical iridectomies were included in a noncomparative case series. Cataract surgery with intraocular lens and prosthetic iris implantation was performed in 10 eyes. The visual acuity, subjective degree of glare disability, postoperative anatomic results, and intraoperative and postoperative complications were evaluated. RESULTS: The mean follow-up was 17.75 months (range 4-48 months). Best-corrected visual acuity improved in nine of 10 eyes (90%) and remained unchanged in one eye. Glare subjectively improved in four of five eyes (80%) of patients complaining of glare preoperatively. All eyes achieved the desired anatomic result. Intraoperative complications included one anterior capsular tear. Postoperative complications included a short period of mild postoperative anterior uveitis in four eyes. Secondary glaucoma was absent. CONCLUSION: In patients with iris deficiency, implantation of prosthetic iris device, and intraocular lens implant following cataract surgery appears to be safe and effective in reducing glare disability and improving visual outcomes.     

Endocapsular iris reconstruction implants for acquired iris defects: a clinical study

PURPOSE: To report the clinical efficacy, safety, and long-term follow-up data on the use of endocapsular iris reconstruction implants (IRIs) during cataract surgery in patients with acquired iris defects. METHODS: Single centre, retrospective, noncomparative, interventional case series. Five eyes of four patients with acquired iris defects and visually significant cataracts underwent clear cornea phacoemulsification and intraocular lens (IOL) implantation combined with insertion of endocapsular IRI. Data on the best-corrected visual acuity (BCVA), degree of preoperative and postoperative glare, photophobia, surgical complications, and long-term implant stability were analysed. Results: In all patients, IRI were successfully placed within the capsular bag during cataract surgery. There were no intraoperative or postoperative complications. Mean follow-up period was 29 months (range, 16-42). BCVA, subjective glare, and photophobia improved in all five eyes. Desired anatomic results were achieved in all of them. CONCLUSIONS: In patients with acquired iris defects, implantation of endocapsular IRI during cataract surgery appears to be a safe and effective procedure. At a mean time gate of 29 months, both IOLs and IRI appeared to remain stable within the capsular bag.     

糖尿病性白内障超声乳化术的临床观察

目的：观察糖尿病性白内障患者施行超声乳化联合人工晶状体植入术后视力变化及其影响因素。方法：对42例48眼糖尿病性白内障患者及48例48眼单纯老年性白内障患者行超声乳化吸除联合人工晶状体植入术,观察术后视力及术后并发症。结果：与对照组相比,糖尿病组术后视力较差,但两组无明显统计学差异。糖尿病组术后角膜内皮水肿、纤维素性渗出和虹膜后粘连显著增多。结论：糖尿病患者白内障术后视力的恢复与眼底病变程度、病程及术后并发症的影响有关。     

白内障摘出人工晶状体植入联合光学虹膜切除术的临床应用

目的:应用小切口非超声乳化白内障摘出+人工晶状体植入联合虹膜光学切除术(以下简称三联术)的方法治疗角膜混浊合并白内障,并评价其疗效。方法:选择角膜白斑、斑翳合并白内障患者13例18眼,根据角膜混浊程度、部位,设计虹膜光学切除部位。为患者施行三联手术治疗,观察术后视力恢复的情况,随访1～3mo。结果:术前视力:光感～数指12眼,<0.1者4眼,0.1～0.2者2眼。术后1wk,裸眼视力>0.3者12眼,>0.1者5眼,无改善者1眼。3mo后最佳矫正视力0.6,0.2～0.3以上的视力14眼,大部分视力不同程度的提高,全部脱盲。结论:小切口非超声乳化白内障摘出+人工晶状体植入联合虹膜光学切除术,可以一次性解决眼前段屈光间质混浊。与传统穿透性角膜移植联合白内障摘除术相比,三联术简化了手术操作,减少了角膜移植术后排斥反应等并发症,根据角膜混浊的程度、部位患者视力获得不同的恢复。三联术操作简单,安全性高,低成本低风险,值得推广。     

瞳孔成形联合虹膜夹人工晶状体植入术治疗外伤性无晶状体眼疗效观察

目的 观察瞳孔成形联合虹膜夹人工晶状体植入术治疗外伤性无晶状体眼的疗效.方法 回顾性分析在我院采用瞳孔成形联合虹膜夹人工晶状体植入术治疗的外伤后无晶状体眼患者17例17眼的临床资料.观察术后视力、角膜内皮细胞计数、眼压、人工晶状体位置、瞳孔情况及术后并发症.结果 17例患者均顺利修补损伤虹膜,瞳孔成形后成功植入虹膜夹人工晶状体,未发生严重手术并发症,人工晶状体位置稳定.术后6个月裸眼视力(0.52 +0.17),较术前视力(0.04±0.02)及术前最佳矫正视力(0.44±0.13)提高.术后6个月角膜内皮细胞计数为(1993.88±127.24)个·mm-1,较术前(2178.88±132.61)个·mm-2减少(P＜0.05),但术后未发现角膜失代偿.术前眼压(15.91 ±2.73)mmHg(1 kPa=7.5 mmHg)与术后眼压(16.69±2.61) mmHg无明显差异(P＞0.05).术后瞳孔大小(4.4±0.2)mm较术前(5.5 +0.3)mm缩小(P＜0.05),患者术后无明显畏光、眩光、复视等不适症状.结论 瞳孔成形联合虹膜夹人工晶状体植入术是治疗外伤虹膜损伤并无有效晶状体囊膜支持的无晶状体眼的安全有效方法.     

特高龄白内障的超声乳化术临床效果

目的观察90岁以上特高龄白内障患者超声乳化手术的安全性及效果。方法回顾性分析90岁以上白内障27例（30眼）超声乳化手术的安全性，观察术后视力及并发症。结果所有患者均能耐受手术。术后视力均较术前有明显改善，术后1月最佳矫正视力，〈0．05者2眼，0．05～0．08者1眼，0．1～0．25者6眼，0．3～0．4者12眼，≥0．5者9眼，与术前相比差异有统计学意义（χ2=36．32，P=0．000）。术中后囊破裂1眼，术后角膜水肿14眼。结论90岁以上特高龄患者超声乳化手术安全有效，可以提高视力，改善生活质量。     

改良四点固定人工晶状体悬吊植入术在无晶状体眼中的有效性及安全性观察

目的：观察改良四点固定人工晶状体悬吊植入术在无晶状体眼中的有效性及安全性。

方法：前瞻性研究。选2020-10/2021-05于我院行改良四点固定人工晶状体悬吊植入术的无晶状体眼患者32例32眼，平均年龄44.56±8.48岁。观察手术前后裸眼视力(UCVA)、最佳矫正视力(BCVA)、角膜散光、术中及术后并发症。

结果：所有患者平均随访4.84±0.64mo，术前UCVA、(LogMAR)为1.25±0.42，末次随访时为0.5±0.25(P<0.001)； 术前BCVA(LogMAR)为0.41±0.19，末次随访时为0.42±0.19(P>0.05)； 术前角膜散光为1.17±0.64D，末次随访时为1.20±0.59D(P>0.05)。术中无并发症发生，术后发生低眼压2眼、高眼压1眼、角膜水肿2眼，无前房积血、玻璃体积血、黄斑囊样水肿、角膜内皮失代偿、人工晶状体倾斜或偏心、缝线外露等并发症。

结论：改良四点固定人工晶状体悬吊植入术可显著提高无晶状体眼患者术后视力、未增加额外角膜散光、并发症少。     

Visual rehabilitation and outcomes for ectasia after corneal refractive surgery

PURPOSE: To analyze the visual outcomes and method of final visual correction in eyes with corneal ectasia after laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK). SETTING: Emory University Department of Ophthalmology and Emory Vision, Atlanta, Georgia, USA. METHODS: This retrospective review comprised 74 eyes of 45 patients with corneal ectasia after LASIK (72 eyes) or PRK (2 eyes). Outcomes included postoperative uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), best corrected visual acuity (BCVA), and refraction; method of final visual correction; and time to rigid gas-permeable (RGP) contact lens failure. RESULTS: Corneal ectasia developed a mean of 19.2 months after surgery. Postoperatively, the mean UCVA was 20/400 and the mean BSCVA before ectasia management was 20/108. After ectasia management, the mean BCVA was 20/37 and the final BCVA was 20/40 or better in 78% of eyes. Final visual correction was achieved with RGP lenses in 77% of eyes, spectacles in 9%, collagen crosslinking in 3%, intracorneal ring segments in 1%, and penetrating keratoplasty (PKP) in 8%. Two eyes with intracorneal ring segments required segment explantation and subsequent PKP. One eye that had PKP had a graft-rejection episode; there were no graft failures. Two eyes (3%) did not require a visual device to improve visual acuity. The mean time for successful RGP lens wear was 24.8 months; 80% of cases initially managed with RGP lenses were successful with this form of treatment. CONCLUSIONS: The majority of eyes developing postoperative corneal ectasia achieved functional visual acuity with RGP lens wear and did not require further intervention. Penetrating keratoplasty can usually be postponed or avoided by alternative methods of visual rehabilitation; however, PKP, when necessary, can provide good visual outcomes.     

有晶状体眼虹膜夹型人工晶状体矫治高度近视眼的3年随访观察

目的 研究有晶状体眼虹膜夹型人工晶状体(ICPIOL)矫治高度近视眼的长期安全性和有效性.方法 高度近视眼患者49例(86只眼),等效球镜度数(SE)(-15.33±3.81)D,植入ICPIOL.术后随访3年,观察手术前后的视力、屈光状态、眼压、角膜、前房、瞳孔、ICPIOL和晶状体、眼底情况,并采用单因素方差分析进行统计学比较.结果 与术前比较,术后1、2、3年的裸眼视力(UCVA)、最佳矫正视力(BCVA)和SE显著改善(F=513.68,20.88,827.65;P＜0.01).术后3年时,UCVA≥0.5有85%,≥0.8有35%;BCVA未见下降,17%比术前提高1行,59%比术前提高≥2行;81%眼的实际屈光度数稳定在预期的±1.00 D,54%稳定在预期的±0.50 D.术后1、2、3年的角膜内皮细胞累积丢失率分别为3.60%、5.78%、7.74%.除了3只眼术中在抓持虹膜固定ICPIOL时有轻度虹膜脱色素,1只眼ICPIOL脚襻脱位重新手术固定,2只眼黄斑出血外,未见其他并发症发生.结论 ICPIOL矫治高度近视术后3年内安全、有效.