脂溢洗方外洗加当归苦参丸内服治疗头部脂溢性皮炎的疗效观察

目的:观察脂溢洗方外洗加当归苦参丸内服治疗头皮脂溢性皮炎的临床疗效。方法:将头部脂溢性皮炎患者102例随机分为两组。治疗组51例,用脂溢洗方外洗,中成药当归苦参丸内服;对照组51例,用采乐洗剂外洗,抗组胺药、B族维生素口服。结果:治疗组总有效率为86.3%,对照组为68.6%。两组比较,差异有显著性意义(P<0.05)。结论:脂溢洗方外洗加当归苦参丸口服治疗头部脂溢性皮炎的临床疗效较好。     

酮康唑洗剂治疗脂溢性皮炎和头皮糠疹148例临床观察

脂溢性皮炎与头皮糠疹为临床常见病，发病原因与卵圆糠就抱子菌密切相关。酮康吐具有抗卵圆形糠秋抱子菌的活性，可用于脂溢性皮炎和头皮糖疹的治疗．1995－10~1997－08，我科使用2％酮康唑洗剂（商品名采乐，西安杨森制药有限公司出品）治疗148例脂溢性皮炎和头皮糠疹患者，现将结果报道如下．1临床资料1．1一般资料148例均为门诊患者，男70例，女78例，年龄18~65岁，脂溢性皮炎92例，头皮糠疹56例．1．2使用方法应用2％团康哩洗剂洗头，先用温水将头皮淋湿，然后用适量广～10ml）2％酮康吐洗剂揉搓按摩头皮3～smin，再用水冲洗干净，每周2…     

2%酮康唑洗剂治疗头皮脂溢性皮炎和花斑癣随机双盲对照…

酮康唑是抗糠秕马拉色菌非常有效的药物。研究证明糠秕马拉色菌在头皮单纯糠疹和脂溢性皮炎的发病机制中起重要作用也是花斑癣的致病菌。本文研究目的是评价２％酮康洗剂和安慰剂洗剂治疗头皮单纯糠疹、头皮脂溢性皮炎和花斑癣的疗效和安全性。     

伊曲康唑口服联合酮康唑洗剂外用治疗脂溢性皮炎的疗效观察

目的观察伊曲康唑口服联合酮康唑洗剂外用治疗脂溢性皮炎的疗效。方法选取我院2009年10月—2012年2月收治的脂溢性皮炎并经常规治疗(口服B族维生素、抗组胺药物和红霉素等)后效果不佳的病例84例,分成两组,其中对照组(40例)单行伊曲康唑治疗,实验组(44例)联合外用酮康唑洗剂。随访1～2个月,对比两组的疗效。结果两组间治疗后相比,实验组的总有效率为91%,高于对照组的75%,差异有统计学意义(P<0.05)。结论运用伊曲康唑口服联合酮康唑洗剂外用治疗脂溢性皮炎,可改善患者的临床症状,提高临床疗效。     

除湿止痒汤内服联合二硫化硒洗剂外用治疗脂溢性皮炎的临床效果

目的 观察除湿止痒汤内服联合二硫化硒洗剂外用治疗脂溢性皮炎的临床效果.方法 回顾性选取2018年6月-2020年6月在重庆市渝北区中医院接受治疗的脂溢性皮炎患者65例,根据治疗方法不同分为观察组35例和对照组30例.对照组单用二硫化硒洗剂外用治疗,观察组在对照组基础上联合除湿止痒汤内服治疗,2组均持续治疗30 d.比较...     

2%采乐洗剂治疗头皮脂溢性皮炎215例疗效观察

脂溢性皮炎是皮肤科最常见疾病之一,治疗方法很多,我科于1997年6月～1999年10月用采乐洗剂(西安杨森:2%酮康唑洗剂)治疗215例脂溢性皮炎取得满意疗效,并以希尔生(2.5%硫化硒洗剂)作对照,现将临床观察结果总结如下:     

复方甲安霜的研制和临床应用

目的根据脂溢性皮炎发病机理,外用雄激素拮抗剂治疗脂溢性皮炎.方法配制复方甲安霜,并与复方甲氟霜双盲法对照观察临床疗效.结果复方甲安霜较对照组疗效好且持久(P＜0.01),并且无明显毒副作用.结论复方甲安霜是治疗脂溢性皮炎的有效、安全制剂.     

采乐洗剂治疗137例脂溢性皮炎和头皮糠疹临床疗效观察

脂溢性皮炎和头皮糠疹是皮肤科常见疾病。酮康唑对该疾病有治疗作用。采乐洗剂（２％酮康唑洗剂）治疗上述疾病获得较好疗效。我科于１９９６－１０－１９９９－０７采用采乐洗剂治疗上述二种头皮疾患,现将临床观察结果总结如下。１一般资料 患者均为门诊病人,男 ６０例,女 ７７例。年龄 １７～４９岁,病程最短５个月,最长１０年,平均２年零７个月。头皮糠疹９２例,脂溢性皮炎４５例,并由此将患者分成２组。２用药方法 两组患者都要用西安杨森制药公司提供的采乐洗剂,每次用量约５～１０ｍｌ,并在头皮上停留５ｍｉｎ,然后用清水…     

酮康唑洗剂的制备及含量测定

酮康唑为咪唑类抗真菌药,具有广谱抗真菌活性,常用于治疗各种真菌感染如体癣、头癣等。由于它对脂溢性皮炎的常见致病真菌糖秕孢子菌有高效的抑制作用和抗雄性激素作用,临床上常用于治疗面部及头部的脂溢性皮炎。酮康唑霜剂、搽剂等外用制剂均见报道,西安杨森制药厂的“采乐洗剂”(含酮康唑2％)虽临床疗效报道甚多,却未公开处方工     

复方枝叶洗剂的制备

复方桉叶洗剂为本医院研制制剂,由大叶桉、苦参、蒲公英、黄柏、蛇床子5味药制成,主要用于脂溢性皮炎、湿疹、皮炎等皮肤炎症的治疗,临床效果显著。现进一步对其制备方法和质量标准进行了研究,旨在为配制过程的质量控制及临床应用提供理论依据。     

比拜克胶囊治疗头皮脂溢性皮炎45例

目的观察比拜克胶囊联合2．5％二硫化硒洗剂外用治疗头皮脂溢性皮炎的临床疗效。方法将90例患者随机分成两组,治疗组45例采用比拜克胶囊内服联合2．5％二硫化硒洗剂外用,对照组45例仅采用2．5％二硫化硒洗剂外用,对患者的临床疗效、复发情况及不良反应进行观察。结果治疗4周后治疗组有效率为91．11％,对照组为68．89％,两组比较差异有统计学意义（P〈0．05）。继续观察8周后复发率治疗组为17．07％,对照组为40．54％,两组比较差异有统计学意义（P〈0．05）。结论采用比拜克胶囊内服联合2．5％二硫化硒洗剂外用治疗头皮脂溢性皮炎,有较好的临床疗效。     

消炎止痒洗剂的鉴别与临床疗效观察

目的:制备消炎止痒洗剂并对其进行鉴别,观察其临床疗效。方法:按处方制成散剂;对其进行理化鉴别和薄层色谱鉴别;将108例典型皮炎及温疹患者随机分为治疗组(65例)与对照组(43例),治疗组采用消炎止痒洗剂浸洗患处,2～3次.d-1;对照组采用复方康纳东霜涂擦患处,2～3次.d-1,2组疗程均为1wk。结果:治疗组和对照组总有效率分别为98.5%和88.4%,治疗组显著优于对照组(P<0.05)。结论:消炎止痒洗剂制备方法简单,使用方便,用于治疗妊娠性皮炎疗效显著,无毒副作用。     

Medicated shampoos for the treatment of seborrheic dermatitis

Seborrheic dermatitis is a common papulosquamous disorder of the skin, affecting 3% to 5% of the population. Dandruff, a less severe form of seborrheic dermatitis, affects a greater proportion of the population. The exact pathogenesis of seborrheic dermatitis is unknown, however colonization of the lipophilic yeast, Malasezzia furfur, and an inflammatory reaction to this yeast each seem to play a role in disease etiology. Therefore, treatment for seborrheic dermatitis is aimed at yeast elimination and inflammation control. Several treatment modalities are available for seborrheic dermatitis and dandruff including shampoos, which contain both active ingredients related to antimycotic or anti-inflammatory effects and also surfactant ingredients that allow these shampoos to replace regular shampoos in affected patients. The literature regarding the treatment of therapeutic shampoos is reviewed, and treatment strategies for managing seborrheic dermatitis with therapeutic shampoos are provided.     

Efficacy and safety of a new once-daily topical ketoconazole 2% gel in the treatment of seborrheic dermatitis: a phase III trial

BACKGROUND: The first gel formulation of ketoconazole has been tested in 2-week treatment courses. OBJECTIVE: To evaluate the efficacy and safety of a new, once-daily, 2-week ketoconazole 2% gel treatment in moderate to severe seborrheic dermatitis. METHODS: Four hundred fifty-nine subjects with moderate to severe seborrheic dermatitis were randomized to receive ketoconazole 2% gel or vehicle gel once daily for 14 days. The primary efficacy was the proportion of successfully treated subjects at day 28 (cleared and almost cleared). RESULTS: A significantly greater percentage of subjects were successfully treated with ketoconazole 2% gel compared with vehicle (25.3% vs. 13.9%, P = .0014). Ketoconazole 2% gel improved erythema, scaling (P = .0022 vs. vehicle), and pruritus. Mean overall symptom severity was reduced by 53% and 39% with ketoconazole gel and vehicle, respectively. Adverse events were few, generally mild or moderate, and similar between treatment groups. CONCLUSION: Once-daily ketoconazole 2% gel is an effective,well-tolerated, convenient, and cosmetically acceptable treatment for moderate to severe seborrheic dermatitis.     

A novel foam formulation of ketoconazole 2% for the treatment of seborrheic dermatitis on multiple body regions

BACKGROUND: A novel topical foam formulation of ketoconazole has been developed for use on the scalp, body, and face. OBJECTIVE: To evaluate the efficacy and safety of twice-daily treatment with ketoconazole 2% foam for seborrheic dermatitis on the scalp, body, and face. METHODS: One thousand one hundred sixty-two subjects, aged 12 years or older, with mild to severe seborrheic dermatitis were randomized to receive ketoconazole foam (n=427), vehicle foam (n=420), ketoconazole cream (n=210), or vehicle cream (n=105) twice daily for 4 weeks. The primary endpoint was the proportion of subjects achieving an Investigator's Static Global Assessment score of 0 or 1 at week 4 (treatment success). RESULTS: A significantly greater percentage of subjects achieved treatment success using ketoconazole foam than vehicle foam (56% and 42%, respectively; P<.0001); ketoconazole foam was shown to be equivalent to ketoconazole cream. Ketoconazole foam was well-tolerated with a low incidence of treatment-related adverse events (14%; 59/427). CONCLUSION: Ketoconazole foam 2% is a safe, effective, and versatile formulation for use on the scalp, body, and face for the treatment of seborrheic dermatitis in patients aged 12 years or older.     

Pimecrolimus 1% cream for the treatment of seborrheic dermatitis: a systematic review of randomized controlled trials

Seborrheic dermatitis is a common, chronic, relapsing inflammatory skin disorder that manifests as erythema, scaling and pruritus in sebum gland-rich areas of the skin. The objective of this article is to evaluate the clinical efficacy of pimecrolimus 1% cream in the treatment of seborrheic dermatitis compared with corticosteroids, antimycotics, placebo or no intervention. Pimecrolimus 1% cream appears to be a well-tolerated and effective treatment for seborrheic dermatitis. It has comparable efficacy, in terms of decreasing severity of erythema, scaling and pruritus, to the standard treatments: topical corticosteroids and antimycotics. However, future studies with more standardized measures of treatment outcome are recommended. More studies may also be conducted to further evaluate pimecrolimus 1% cream as a long-term maintenance therapy for seborrheic dermatitis.     

中医情志护理干预对脂溢性皮炎患者治疗作用的影响分析

目的 探讨中医情志护理干预对治疗脂溢性皮炎患者的疗效影响.方法 将80例脂溢性皮炎患者随机分为干预组和对照组,各40例.对照组采用常规护理方法,干预组在常规护理的基础上,采用根据中医辨证施护理论制定的情志护理措施.2个月后比较两组疗效及治疗依从性.结果 干预组患者治疗的依从性95.0％,对照组62.5％;干预组治疗有效率87.5％,对照组52.5％;两组比较,差异具有统计学意义(均P＜ 0.01).结论 对脂溢性皮炎患者进行中医情志调节护理,有助于改善患者情绪,消除焦虑心理,提高治疗依从性,有利于疾病的治愈.     

萘替芬酮康唑乳膏联合地奈德乳膏治疗面部脂溢性皮炎疗效观察

目的:观察萘替芬酮康唑乳膏及地奈德乳膏联合疗法治疗面部脂溢性皮炎的临床疗效。方法:30例面部脂溢性皮炎应用萘替芬酮康唑乳膏及地奈德乳膏联合外用治疗,治疗,2,3周及4周结束后观察临床疗效及不良反应,停药后1,2周随诊。结果:4周后痊愈率为86.67%,总有效率为100%。停药后1,2周随诊未见复发。未发现不良反应。结论:此方法治疗面部脂溢性皮炎治愈率高,疗效显著,耐受性好,安全性高,复发率低,是一种较理想的治疗面部脂溢性皮炎的有效方法。