小儿高热惊厥的急救护理

目的：对小儿高热惊厥的急救措施和护理方法进行分析和总结，提供临床参考。方法：回顾性分析2010年7月－2013年12月我院收治的100例高热惊厥患儿的临床资料和急救护理措施。结果：通过对患儿进行相关的急救及护理，再通过了解病因进行治疗，很快便缓解了惊厥症状，未见有精神疾病遗留，住院8－10天即可痊愈出院。结论：在对患高热惊厥的患儿进行急救时，最关键的是有效的降温方法，在降温的基础上进行止惊，能够快速的缓解高热惊厥的症状，于此同时，再对患者进行病因治疗，预防再次发生高热惊厥。     

小儿高热惊厥的急救与护理

目的：探讨小儿高热惊厥的急救和护理措施。方法：对我院36例小儿高热惊厥患儿的急救和护理的临床资料进行回顾性分析。结论：小儿高热惊厥治疗的关键是迅速控制惊厥、高热,快速把体温降下来加强护理。     

小儿高热惊厥52例分析及护理体会

目的：探讨小儿高热惊厥的病因、临床特点、急救措施及护理对策。方法：采取合理降温、止惊、及时的呼吸管道管理及基础护理、恰当的健康教育等综合护理措施。结果：本组52例患儿治愈47例，好转4例，1例早产儿合并肺部感染死亡。结论：小儿高热惊厥起病急，护士只有熟练掌握各种有效控制惊厥的措施及细致周到的护理方法、密切观察病情、配合医生采取果断有效的治疗措施，才能使患儿早日治愈。     

小儿高热惊厥的急救与护理

目的:探讨小儿高热惊厥的急救和护理措施。方法:对我院36例小儿高热惊厥患儿的急救和护理的临床资料进行回顾性分析。结论:小儿高热惊厥治疗的关键是迅速控制惊厥、高热,快速把体温降下来加强护理。     

73例小儿高热惊厥的护理体会

目的：探讨对高热惊厥患儿急救护理的临床效果。方法：回顾性分析3年来我院收治的73例高热惊厥患儿的临床资料,研究其急救护理方法及卫生宣教工作在治疗和预防小儿高热惊厥中的作用。结果：本组73例高热惊厥患儿,经治疗后均痊愈,住院天数5～10d,治疗后随访,再次发作患儿12例,余患儿均未再次发作。结论：护理人员应熟练掌握惊厥的急救程序,配合医生急救。做好小儿高热惊厥患儿及家长的健康宣教工作,使患儿家长加强对高热惊厥及其并发症的认识,积极预防高热惊厥的发生。     

小儿高热惊厥的急救与护理

目的：探讨小儿高热惊厥的护理措施。方法：对处于惊厥状态的患儿首先选择快速有效的抗惊厥药物，待惊厥缓解后再行控制高热并积极治疗原发病。结果：通过对本组23例病人进行护理，患儿在短时间内停止惊厥。经过对症治疗护理无并发症。结论：利用抗惊厥药物、给氧、物理降温等护理措施对高热惊厥的患儿进行护理可以有效控制惊厥。     

小儿高热惊厥的急救与护理体会

目的探究小儿高热惊厥的急救与护理方法。方法选择我院自2012年8月至2015年8月收治的60例高热惊厥的患儿,对其临床资料进行回顾性分析。结果所有患儿经医护人员的救助下均痊愈出院。结论合理的急救及护理措施,是治疗小儿高热惊厥的关键。     

小儿高热惊厥（FC）的急救及护理分析

目的研究急救与护理对小儿高热惊厥的临床疗效。方法选取本院121例小儿高热惊厥患儿,通过本院急救及护理措施后根据治愈情况、复发情况及后期随访的资料来研究针对于小儿高热惊厥急救与护理的重要性。结果调查发现病因中上呼吸道感染人数较多,差异有统计学意义（P〈0.01）;患儿家属焦虑等负面情绪及临床医务人员对患儿配合医疗的满意度护理前、后比较差异显著（P〈0.05）;干预前、后的护理指标经t检验,差异有统计学意义（P〈0.05）;通过积极急救与治疗后患儿无死亡病例;经过2年追踪随访调查,复发率近23.97%（29/121）。结论小儿高热惊厥的发病因素复杂、复发率高、针对小儿脑组织损害严重。在发病初期急救与护理是救治该病的最重要因素。     

浅谈小儿高热惊厥的护理体会

目的:探讨小儿高热惊厥的护理措施。方法:对处于惊厥状态的患儿首先给予针刺人中、合谷或十宣等穴位及氧气吸入等的急救处理,待惊厥缓解后再行控制高热并积极治疗原发病。结果:通过对本组32例病人进行护理,患儿在1分钟～5分钟停止惊厥。经过对症治疗护理无并发症。结论:利用针刺、给氧、物理降温等护理措施对高热惊厥的患儿进行护理可以有效控制惊厥。     

针对性的急救护理模式在小儿高热惊厥急诊护理中的应用效果研究

目的探究小儿高热惊厥采用针对性急救护理的临床效果。方法选择在我院进行高热惊厥治疗的70例小儿病患为研究样本,其住院时间均在2017年9月至2018年9月之间,采取随机数字表法将其分成组均35例的对照组以及研究组,予以对照组患儿常规护理模式,予以研究组患儿针对性急救护理措施。对比每组惊厥消失时间、退热时间、并发症出现率以及护理服务满意率。结果研究组在惊厥消失时间、退热时间以及并发症出现率方面均低于对照组,结果具有统计学意义(P0.05);研究组与对照组护理服务满意率分别是100.00%、77.14%,2组结果比较有统计学意义(P0.05)。结论对高热惊厥的小儿病患实施针对性急救护理措施,可有效缓解其临床表现,降低并发症出现率,值得临床大力推广。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.