Phosphatidylcholine liposomes in the repair of the hepatocyte plasma membrane

Department of Biochemistry, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 110, No. 7, pp. 94–96, July, 1990.     

Effect of fractions obtained by gel-filtration of chalone-containing preparation from Ehrlich's ascites carcinoma on mitotic activity and DNA synthesis in the tumor of origin

Department of Biology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 106, No. 8, pp. 202–204, August, 1988.     

Effect of inversion of daylight and darkness on the general structure of biological rhythms of mitotic activity in thymocytes

Department of Biology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 109, No. 5, pp. 481–483, May, 1990.     

Effect of phytoadaptogens on biorhythms of hemostasis parameters in dogs

Department of Pathological Physiology, North-Ossetian Medical Institute, Vladikavkaz. Department of Biology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 113, No. 1, pp. 87–89, January, 1992.     

Action of contrast media on spontaneous erythrocyte aggregation

Department of Molecular Pharmacology and Radiobiology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 111, No. 3, pp. 274–276, March, 1990.     

Effect of adrenalin on inhibition of mitosis by a chalone in Ehrlich's ascites carcinoma

Department of Biology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 105, No. 3, pp. 345–347, March, 1988.     

Action of the immunomodulator T-activin on electrical properties of the thymus plasma cell membrane studied by fluorescent probes

Department of Biophysics, and Department of Immunology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR R. V. Petrov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 110, No. 10, pp. 402–404, October, 1990.     

Levels of DNA synthesis in Ehrlich's ascites tumor cells in culture,treated with different concentrations of a chalone-containing preparation

Department of Biology, Medico-Biological Faculty, Russian National Medical University. (Presented by Academician of the Russian Academy of Medical Sciences Yu. A. Romanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 114, No. 12, pp. 651–652, December, 1992.     

Morphology of tissue components of layers of the rat myocardium in the early stages of myocardial hypertrophy

Department of Morphology and Cytology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR D. S. Sarkisov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 113, No. 2, pp. 210–211, February, 1992.     

Comparison of the proliferative and immunoglobulin-secreting ability of peripheral blood lymphocytes of healthy subjects and patients with B-cell immunoproliferative disease

Department of Immunology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR R. V. Petrov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 112, No. 12, pp. 627–628, December, 1991.     

Protective role of estradiol in extremal states

Department of Molecular Pharmacology and Radiobiology, Medico-Biological Faculty, Russian National Medical University, Moscow. (Presented by Academician of the Russian Academy of Medical Sciences P. V. Sergeev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol, 114, No. 11, pp, 497–500, November, 1992.     

Morphological analysis of specialized cardio myocytes of the conducting system of the vagotomized rat heart

Light-optical and electron-microscopic investigations were made of the specialized conducting system of the rat heart at various times after vagotomy. The dynamics of the tissue and cellular changes are described. Amosaic pattern of cellular responses was found at all times after denervation in all parts of the conducting system and in all types of specialized cardiomyocytes.Department of Morphology and Cytology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Kupriyanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 9, pp. 378–381, September, 1978.     

Hydroxylation of xenobiotics and steroids in the endoplasmic reticulum of the rat liver

A polarographic method is suggested and can be recommended as a simple device for measuring the rates of oxidation of steroid hormones and xenobiotics. The rate of hydroxylation of steroids depends, it is suggested, on the polarity of the molecule of the oxidation substrate.Department of Molecular Pharmacology and Radiobiology, Medico-Biological Faculty, and Central Research Laboratory, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. A. Pokrovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 3, pp. 299–301, March, 1976.     

Seasonal changes in some ultrastructural indices of the ventricular myocytes ofRana ridibunda

Certain ultrastructural characteristics of the ventricular myocardium ofRana ridibunda (lateral contacts, intercalated disks, mitochondria) were studied in the spring and fall by electron microscopy coupled with morphometric analysis. The results point to seasonal differences in the ultrastructure of the cardiomyocytes and the conclusion was confirmed by the results of quantitative analysis.Department of Morphology and Cytology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Kupriyanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 81, No. 6, pp. 732–735, June, 1976.     

Immunochemical analysis of glial and neuronal fractions of rat brain

A method of obtaining antineuronal and antiglial immune sera is described. The results of a quantitative immunochemical analysis of antigens of neuronal and glial fractions of rat brain are given. Neurons were shown to contain four, and glia three brain-specific proteins; in addition, one or two proteins are common to these cellular fractions.Department of Normal Physiology, Moscow Medical Stomatological Institute. Course of Physiology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR N. A. Fedorov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 2, pp. 156–158, February, 1977.     

Erythrocyte superoxide dismutase activity in rats subjected to a toxic regime of intermittent hyperbaric oxygenation

The development of toxic manifestations in rats exposed to hyperoxia is accompanied by a significant decrease in the activity of erythrocytic superoxide dismutase (SOD). Incubation of hemolysates from control animals with H₂O₂ (10^–3 M) or cumene peroxide (1.6\10^–4 M) also led to a marked decrease in the initial SOD activity. The decrease in the initial SOD activity during hyperoxia is thus evidently connected with the formation of peroxidation products in the cells.Department of Hyperbaric Oxygenation, All-Union Research Institute of Clinical and Experimental Surgery. Department of Biochemistry, Medico-Biological Faculty, Second Moscow Medical Institute. (Presented by Academician B. V. Petrovskii.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 959–961, August, 1976.     

Investigation of the mechanism of action of ouabain and cyclic AMP of the transport of calcium ions by rat heart mitochondria

The action of ouabain and cyclic AMP on the Ca-accumulating capacity and outflow of Ca²⁺ ions from loaded rat heart mitochondria was studied by the tetracycline probe method. In the course of the investigations no effect of ouabain on these processes was found. Cyclic AMP did not act on Ca binding by the mitochondrial membrane but it induced rapid liberation of Ca²⁺ from organelles loaded with these ions.Department of Molecular Pharmacology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR S. S. debov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 83, No. 2, pp. 158–160, February, 1977.     

Participation of phytohemagglutinin-transformed mouse lymphocytes in the graft versus host reaction

Transformed lymphocytes obtained by stimulating lymph node cells of CBA mice with phytohemagglutinin (PHA) do not give the graft versus host reaction (GVHR) if injected into sublethally irradiated (CBA×C57BL/6) F₁ hybrids. In a population of PHA-stimulated cells the GVHR was induced by small lymphocytes having the same concentration of antigens, detectable by antilymphocytic serum, as intact lymphocytes.Department of Immunology, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR Yu. M. Lopukhin.) Translated from Byulletin' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 9, pp. 1096–1098, September, 1976.     

Effect of sarcolysin on glutathione peroxidase and glutathione reductase activity in sarcoma C-45

A decrease in glutathione peroxidase and glutathione reductase activity in sarcoma C-45 was discovered during the period of its most rapid growth. Repeated injections of sarcolysin (1.2 mg/kg, intraperitoneally) caused a sharp decrease in the activity of both enzymes and a simultaneous decrease in the ratio between glutathione reductase and glutathione peroxidase activities. It is suggested that the glutathione redox enzyme system plays an important role in the mechanisms of the antitumor action of chemotherapeutic agents.Laboratory of Biochemistry, Rostov-on-Don Oncologic Research Institute. Department of Biochemistry, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR V. N. Orekhovich.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 11, pp. 597–600, November, 1977.     

Action of cell extract of Ehrlich's mouse ascites tumor on mitotic activity and DNA synthesis in that tumor

An extract of cells of Ehrlich's ascites tumor inhibits the proliferative activity of its cells tissue specifically. The effect is expressed as a marked decrease in the number of dividing and DNA-synthesizing cells after injection of the extract. The mitotic index falls considerably as early as 2 h after the injection, reaches a minimum after 4–5 h, and returns to the control level again after 9–12 h. The radioactive index is on the whole uniformly low during the 18 h of the experiment.Department of General Biology and Genetics, Medico-Biological Faculty, N. I. Pirogov Second Moscow Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR V. V. Kupriyanov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 7, pp. 86–88, July, 1977.