播散性组织胞浆菌病一例

播散性组织胞浆菌病一例全胜麟李明吴运超黄靖李莹男，６６岁。因反复咳嗽，咳痰１０余年，加重伴气喘一月余，于９５年１１月１７日入院。患者入院前一月无明显诱因出现咳嗽，咳痰，气喘，活动后加重，乏力，门诊拟诊为：肺心病，肺部感染。经抗生素治疗２周无效入院。有...     

累及大肠的播散型组织胞浆菌病1例

1 临床资料 患者男,70岁,退休教师.因＂反复腹泻、发热8个月加重伴消瘦半年＂于2008年6月23日入院.2007年10月初,患者无明显诱因出现腹泻,黄色稀烂便,无脓血,量不多,3～4次/d;有轻微里急后重,伴少量黏液,无腹痛,体温37.5℃～38℃,双下肢水肿.     

播散型组织胞浆菌病误诊内脏利什曼病1例

2005年3月21日云南省红河州弥勒县疾病预防控制中心报告内脏利什曼病1例。经调查核实,该患者为播散型组织胞浆菌病误诊内脏利什曼病,现报告如下:1临床资料患者,男性,29岁,云南弥勒县人,2005年3月6日以“腹胀、腹泻2月,发热,皮肤疱疹6d,黑便1d”入住弥勒县医院。检查:T39.3℃,P1     

播散型组织胞浆菌病四例

我科近年来收治播散型组织胞浆菌病（PDH）4例,其中1例误诊为黑热病死亡,3例用H性霉素B治愈。现报道如下。临床资料1．一般资料：男性3例,女性1例,年龄25～46岁,平均年龄30．75岁。持续发热l～6个月（平均5个月）入院。五例曾有HBV感染史5年,1例病后2个月并发2型糖尿病。     

播散型组织胞浆菌病三例

组织胞浆菌病（Ｈｉｓｔｏｐｌａｓｍｏｓｉｓ,ＨＰ）是地区性非条件性真菌传染病,流行于北美洲,散发于新加坡和菲律宾。我国自１９５３年首例报道以来有零星病例报道。现将我科诊治的３例ＨＰ报道如下。例１,女性,３６岁,工人。高热、肝脾肿大、全血细胞减少３月入...     

播散型组织胞浆菌病1例

本文报道了播散型组织胞浆菌病误诊黑热病1例。     

播散性组织胞浆菌病误诊黑热病5例报告

１９９４年，一例被诊断为黑热病的病人来我所求治，我们复核鉴定其骨髓片时，发现病原体并非利什曼原虫而是美洲型荚膜组织胞浆菌。该病人的肝、脾组织切片由华西医科大学送美国国防部ＡＦＩＰ感染与寄生虫病病理科鉴定，证实了我们的结论，这是我省的第一例组织胞浆菌病...     

播散型组织胞浆菌病5例

组织胞浆菌病 (ｈｉｓｔｏｐｌａｓｍｏｓｉｓ)是经蝙蝠、鸡等鸟禽传播的一种少见的系统性真菌病 ,由组织胞浆菌引起以网状内皮系统为主的慢性感染 ,近年来国内本病报道增多 ,应引起重视。根据本病的临床特点分为无症状型、急性肺型、播散型和慢性肺型〔1〕。播散型临床表现多种多样 ,诊断困难。现将我院收治的 5例报道如下。1　一般资料我院收治的组织胞浆菌病 5例中 ,男 4例 ,女 1例 ,均为重庆市人。为工人或干部 ,病前体健。年龄 2 8～ 6 0岁。入院前病程 5 0天～ 8个月 ;发热 4例 12天～ 8月 ,1例为不规则发热 ,3例为持续发热 (37℃～ 4…     

播散性组织胞浆菌病九例临床及骨髓象分析

播散性组织胞浆菌病是由组织胞浆菌(Histoplasma capsulatrm，HC)引起的深部真菌病，以侵犯单核巨噬系统为主。表现为肝、脾、淋巴结肿大，体重减轻，发热、贫血及白细胞减少等。易误诊为恶性组织细胞增生症、黑热病及结核病等，提高对本病的认识，避免误诊十分必要。     

播散性组织胞浆菌病1例

本例患者因发热入院,既往无基础疾病,其骨髓检查及骨髓组织宏基因组学第二代测序中检出荚膜组织胞浆菌,确诊为组织胞浆菌病,经两性霉素B及伊曲康唑抗真菌治疗后病情好转。临床医师应提高对该疾病的认识,减少误诊、漏诊。     

Disseminated histoplasmosis associated with the acquired immune deficiency syndrome

Disseminated histoplasmosis developed in a previously healthy man as the initial manifestation of the acquired immune deficiency syndrome. Following apparently successful therapy with intravenous amphotericin B, he presented two months later with a subacute pneumonitis syndrome diagnosed by bronchoscopy as Pneumocystis carinii pneumonia. He showed response to intravenous trimethoprim/sulfamethoxazole with resolution of his symptoms and clearing of chest radiographic findings. While he was receiving antibiotics, oral candidiasis developed and has persisted for more than two months despite topical therapy and discontinuation of all antibiotics.     

对获得性免疫缺陷综合征主要机会性感染的认识

获得性免疫缺陷综合征(AIDS)是由人类免疫缺陷病毒(HIV)感染引起的一种传染病。其特征是HIV特异性的攻击CD4+T淋巴细胞．造成CD4+T淋巴细胞数量和功能进行性破坏,患者出现各种机会性感染或肿瘤,导致AIDS。所以认识和了解AIDS主要机会性感染的临床特点对提高临床医师对其诊治水平有很大帮助,本文对AIDS几个主要的机会性感染的临床特点和诊治叙述如下。     

Disseminated histoplasmosis in patients with the acquired immune deficiency syndrome

The ongoing epidemic of acquired immune deficiency syndrome (AIDS) has affected homosexual men, intravenous (IV) drug abusers, Haitians, hemophiliacs, and others. Defects in cell-mediated immunity place these patients at risk for opportunistic infections. We recently saw three men from Alabama with disseminated infection due to Histoplasma capsulatum. Two of these men were homosexual and the other was an IV drug abuser. These three patients had evidence of depressed cellular immunity consistent with a diagnosis of AIDS. Infection caused by organisms indigenous to certain geographic areas of the United States may become more common in patients with AIDS as the epidemic continues.     

获得性免疫缺陷综合征合并肠结核1例

文献报道获得性免疫缺陷综合征(acquired immune deficiency syndrome,AIDS)合并肠结核很少,临床表现和内镜特点不典型,易误诊.本文对1例手术证实为合并肠结核的AIDS病例进行分析,旨在提高对AIDS继发肠病的诊断认识,减少误诊误治.     

Progressive disseminated histoplasmosis in patients with the acquired immune deficiency syndrome: a report of 12 cases and a literature review

Progressive disseminated histoplasmosis is an increasingly common cause of infection in patients with acquired immune deficiency syndrome (AIDS) from areas endemic for histoplasmosis. We report 12 cases of progressive disseminated histoplasmosis associated with AIDS and review 20 previously reported cases. The clinical presentation of progressive disseminated histoplasmosis is nonspecific with persistent fever, weight loss, and splenomegaly. Frequently progressive disseminated histoplasmosis was the initial clue to the presence of AIDS. Bone marrow culture is the best method for establishing a diagnosis. Relapses were common both with ketoconazole and after a 2.0 to 2.5 g course of amphotericin B. This suggests a 2.0 to 2.5 g course of amphotericin B followed by long term ketoconazole suppression may be the best therapeutic regimen in these patients.     

播散型组织胞浆菌病1例

本文报道了播散型组织胞浆菌病误诊黑热病1例。