瘦素及胰岛素样生长因子-Ⅰ与卵泡发育的关系

目的：探讨卵泡液和血清中瘦素（Leptin）与胰岛素样生长因子-I（IGF-I）水平与卵泡发育的关系。方法：应用放射免疫法（RIA）检测67例患者取卵日血清及卵泡液中的Leptin与IGF-I水平。结果：（1）取卵日血清中的Leptin水平为（13．20±5．43）mg／L，显著高于卵泡液中kptin水平（10．86±5．73）mg／L，P〈0．05；卵泡液中的Leptin水平与血清中的Leptin水平呈正相关（r=0．84，P〈0．001）。血清中的IGF-I水平为（7．18±4．58）mg／L，显著高于卵泡液中IGF-I水平（4．36±3．03）mg／L（P〈0．05），卵泡液中的IGF-I水平与血清中的IGF-I水平呈正相关（r=0．79，P〈0．001）；（2）卵巢低反应型者的血清及卵泡液中Leptin水平显著高于卵巢中高反应型者，差异有显著性（P〈0．05）；（3）三种卵巢反应类型的血清及卵泡液中IGF—I水平比较，差异无显著性（P〉0．05）；（4）卵泡液及血清中的Leptin水平与IGF—I水平无明显的相关性（r=-0．079，P〉0．05）及（r=-0．127，P〉0．05）。结论：（1）卵泡液中的Leptin及IGF-I均来自血清；（2）高浓度的Leptin可能抑制卵泡发育，而低浓度的Leptin可能对卵泡发育没有影响；（3）体内IGF-I可能与其受体结合后发挥对卵泡发育的调节作用；（4）Leptin与IGF-I之间无明显相关关系。     

瘦素在超排卵周期的变化及对体外受精-胚胎移植结局的影响

目的 :探讨超排卵对瘦素水平的影响以及瘦素水平对体外受精 -胚胎移植 (IVF- ET)结局的影响。方法 :应用酶联免疫吸附法和放射免疫法分别测定 39例 IVF- ET患者在注 FSH、HCG前和取卵前的血清瘦素及排卵前卵泡的卵泡液瘦素、E2 水平。结果 :血清瘦素水平在注 HCG前 (2 6 .1± 2 .3)μg/ L明显高于注 FSH前 (9.3± 1.0 )μg/ L和取卵前 (15 .8± 2 .3) μg/ L,P均 <0 .0 0 1;卵泡液 (18.5± 2 .2 ) μg/ L和同期血清 (15 .8± 2 .3) μg/ L的瘦素水平比较 ,经 t检验无显著性差异 ;妊娠组的卵泡液和同期血清瘦素水平 (11.7± 1.8) μg/ L和 (8.7± 1.5 ) μg/ L明显低于非妊娠组的卵泡液和同期血清瘦素水平 (2 0 .8± 2 .7) μg/ L和 (18.3± 2 .9) μg/ L,P<0 .0 5。结论 :超排卵后瘦素浓度过高可能不利于卵泡的生长和发育。     

人卵泡液TNF-α和IL-6的水平及其对卵巢功能的影响

目的　测定卵泡液中肿瘤坏死因子 -α(TNF-α)和白细胞介素 - 6 (IL- 6 )水平 ,并探讨其与雌二醇 (E2 )产生及卵母细胞成熟度的关系 .方法　酶联免疫法测定 97份卵胞液及2 6份血清标本的 TNF- α和 IL- 6水平 ,放射免疫法测定 E2 水平 ,并记录每份卵泡液中卵母细胞的成熟度 .结果　卵泡液中 TNF- α和 IL- 6水平分别为 (2 6 .5± 7.2 ) ng·L- 1和 (32 8.0± 48.7) ng· L- 1 ,分别较血清中 TNF-α和 IL - 6的水平高 9倍和 2 0倍 (P<0 .0 1) ;卵泡液 TNF- α和 IL- 6水平与卵泡液中 E2 水平及卵母细胞成熟度呈正相关 (r值为 0 .6 48和 0 .6 92 ,P<0 .0 1) .结论　卵泡液中存在较高水平的 TNF-α和IL- 6 ,其与 E2 产生及卵母细胞成熟度有一定关系     

白细胞介素6及肿瘤坏死因子-α对体外受精-胚胎移植结局的影响

目的 :探讨在体外受精 -胚胎移植 (IVF -ET)过程中血清及卵泡液中的白细胞介素 -6(IL -6)、肿瘤坏死因子 -α(TNF -α)水平与卵泡发育、卵巢内分泌、激素反应类型、年龄、胚胎质量及妊娠之间的关系。方法 :用放射免疫方法检测了 98例患者 (共 10 2周期 )卵泡早期、卵泡中期和取卵日血清中的IL -6、TNF -α水平及取卵日卵泡液中的IL -6、TNF -α水平。结果 :⑴在超促排卵周期中 ,血清中的IL -6水平及IL -6/TNF -α比值随着卵泡的逐渐发育成熟而逐渐升高 ,但血清TNF -α的水平则随着卵泡发育进程而逐渐降低 ,各组间存在极显著性差异 (P均 <0 .0 0 1) ;⑵取卵日卵泡液中的IL -6、TNF -α水平显著高于血清中上述细胞因子的水平 (P <0 .0 0 1) ,⑶随着获卵数的增加 ,卵泡液中IL -6、TNF -α水平显著降低 (P均 <0 .0 0 1) ;而卵泡液IL -6/TNF -α比值则随着获卵数的增加显著升高 (P均<0 .0 5) ;⑷年龄≤ 3 0岁组卵泡液中的IL -6水平小于年龄 >3 1岁组 (P <0 .0 5) ,年龄 3 1～ 3 5岁组与年龄 >3 5岁组之间的卵泡液IL -6水平无显著性差异 (P >0 .0 5) ,不同年龄组间卵泡液TNF -α水平及IL -6/TNF -α比值均无显著性差异 (P >0 .0 5) ;⑸高质量胚胎比≥ 0 .5组的卵泡液IL -6、TNF -α浓度较 <0 .5组显著降低 (P     

瘦素及胰岛素样生长因子-Ⅰ与卵泡发育的关系

目的:探讨卵泡液和血清中瘦素(Leptin)与胰岛素样生长因子-Ⅰ(IGF-Ⅰ)水平与卵泡发育的关系.方法:应用放射免疫法(RIA)检测67例患者取卵日血清及卵泡液中的Leptin与IGF-Ⅰ水平.结果:(1)取卵日血清中的Leptin水平为(13.20±5.43)mg/L,显著高于卵泡液中Leptin水平(10.86±5.73)mg/L,P＜0.05;卵泡液中的Leptin水平与血清中的Leptin水平呈正相关(r=0.84,P＜0.001).血清中的IGF-I水平为(7.18±4.58)mg/L,显著高于卵泡液中IGF-I水平(4.36±3.03)mg/L(P＜0.05),卵泡液中的IGF-Ⅰ水平与血清中的IGF-Ⅰ水平呈正相关(r=0.79,P＜0.001);(2)卵巢低反应型者的血清及卵泡液中Leptin水平显著高于卵巢中高反应型者,差异有显著性(P＜0.05);(3)三种卵巢反应类型的血清及卵泡液中IGF-Ⅰ水平比较,差异无显著性(P＞0.05);(4)卵泡液及血清中的Leptin水平与IGF-Ⅰ水平无明显的相关性(r=-0.079,P＞0.05)及(r=-0.127,P＞0.05).结论:(1)卵泡液中的Leptin及IGF-Ⅰ均来自血清;(2)高浓度的Leptin可能抑制卵泡发育,而低浓度的Leptin可能对卵泡发育没有影响;(3)体内IGF-Ⅰ可能与其受体结合后发挥对卵泡发育的调节作用;(4)Leptin与IGF-Ⅰ之间无明显相关关系.     

醒脑静注射液对脑缺血-再灌注损伤家兔血清白介素-8的影响

目的 :观察醒脑静注射液 (XNJI)对脑缺血 再灌注损伤 (CIRI)家兔血清白介素 8(IL 8)水平的影响 ,并探讨其脑保护机制。方法 :2 8只家兔随机分为假手术对照组 (C组 )、缺血再灌注组 (I R组 )和醒脑静注射液组 (XNJI组 ) ,分别在缺血前、缺血 3 0min、再灌注 3 0min、60min、12 0min时取静脉血 ,测定血清IL 8浓度 ,实验结束后取脑组织观察脑超微结构的变化。结果 :脑缺血 再灌注期间 ,I R组不同时点血清IL 8水平明显高于XNJI组 ,缺血 3 0min为 (0 .62± 0 .18)ng·L-1及 (0 .43± 0 .0 8)ng·L-1,P <0 .0 5 ;再灌注 3 0min ,为血清IL 8水平 (0 .73± 0 .19)ng·L-1及 (0 .45± 0 .0 9)ng·L-1;再灌注 60min ,血清IL 8水平为 (0 .87± 0 .2 9)ng·L-1及 (0 .47± 0 .0 6)ng·L-1;再灌注 12 0min血清IL 8水平为 (1.0 3± 0 .43 )ng·L-1及 (0 .44± 0 .0 7)ng·L-1,再灌注各时点组均P <0 .0 1,超微结构发生异常改变 ;XNJI组不同时点血清IL 8浓度显著低于I R组 (XNJI组缺血 3 0min为(0 .48± 0 .0 7)ng·L-1,P <0 .0 5 ;再灌注 3 0min为 (0 .5 0± 0 .0 8)ng·L-1;再灌注 60min为 (0 .5 5± 0 .14)ng·L-1;再灌注 12 0min为 (0 .5 9± 0 .17)ng·L-1,再灌注各时点组P <0 .0 1) ,其超微结构异常改变较I R组     

正常月经周期中血清瘦素与雌激素的关系

目的 :探索健康妇女正常月经周期中血清瘦素与雌激素的关系 .方法 :①对 18例月经规则妇女 (2 8± 1)d ,用放射免疫法分别在其月经第 1,7,14和 2 1d测定血清瘦素及性激素 (FSH ,E2 ,PRO ,T) .②对 19例不孕妇女 ,在受精前用FSH 2 2 5IU·d-1治疗后第 3d、第 5d用放免法测定其血清瘦素及雌激素浓度 .结果 :①血清瘦素在月经周期中的生理性变化 ,月经第 1d ,血清瘦素为 (5 .4 9± 1.0 8) μg·L-1,随着卵泡的发育成熟 ,瘦素水平逐渐升高 ,14d达高峰 (9.2 8± 1.87) μg·L-1,其差异有显著性 (P <0 .0 1) .②用FSH治疗 3,5d ,血清雌激素浓度和瘦素水平 [(89.0 8± 18.0 7)ng·L-1,(10 .99± 1.94 ) μg·L-13rdday],[(12 6 .2 6± 19.79)ng·L-1,(14 .78± 2 .0 0 ) μg·L-15thday]均较治疗前 [(5 8.5 9± 6 .4 0 )ng·L-1,(5 .4 6± 1.16 ) μg·L-1]明显升高 (P <0 .0 1) .结论 :月经周期中血清瘦素和雌激素的变化一致 ,雌激素参与瘦素分泌的调节或瘦素的分泌调节与雌激素有关     

超排卵时卵巢对促性腺激素的反应与颗粒细胞促卵泡激素受体的表达

目的 :探讨促排卵周期卵巢对促性腺激素反应性与颗粒细胞促卵泡激素受体 (FSHR)表达的关系。方法 :根据取卵时卵泡发育数不同 ,将卵巢对促排卵药物的反应分为低反应型 (卵泡数≤ 3个 )、中反应型 (卵泡数 4～13个 )和高反应型 (卵泡数≥ 14个 ) ,分别为 11例、15例和 13例。采用逆转录聚合酶链反应 (RT- PCR)测定 3种反应类型的卵泡颗粒细胞 FSHR m RNA的表达量。结果 :低反应型 FSHR m RNA表达量显著低于中、高反应型 (相对积分值分别为 0 .5 4± 0 .0 7、0 .90± 0 .17和 1.2 0± 0 .4 5 ,P<0 .0 5 )。结论 :卵巢对促性腺激素的反应与颗粒细胞FSHR m RNA的表达量高低有关。     

VF超促周期妇女血清及卵泡液中血管

目的检测血管内皮生长因子(VEGF)在体外受精-胚胎移植(IVF-ET)超促排卵周期中不孕妇女血清及卵泡液中的水平。方法收集IVF治疗的187个因输卵管因素年龄24～38岁的不孕妇女在促性腺激素(Gn)注射日、人绒毛膜促性腺激素(HCG)注射日的血清和卵泡液,用酶联免疫方法测定VEGF在血清和卵泡液中的水平。结果 HCG日血清VEGF的水平明显高于Gn启动日(135.36±1.87)ng/L与(70.34±1.33)ng/L(P<0.01);随着年龄的增长卵泡液VEGF的水平呈上升趋势(r=0.493,P<0.01)两者呈正相关;获卵数≥20个患者单个卵泡中VEGF的水平低于获卵数≤5个的患者(1299.63±43.70)ng/L与(2460.23±548.45)ng/L,但差异无统计学意义(P>0.05)。结论随着促排卵过程中卵泡的发育,血清中VEGF的水平明显增多;随着年龄的增加VEGF在卵泡液中的水平明显升高。     

克罗米芬加补佳乐治疗排卵障碍性不孕症107例

目的 :探讨克罗米芬 (clomiphenecitrate ,CC)加用补佳乐 (progynova ,PGV)对排卵障碍性不孕症的治疗效果 .方法 :将 1 0 7例排卵障碍性不孕症患者随机分为 3组 ,CC组 36例 ,单纯给予克罗米芬治疗 ;CC +PGV组 38例 ,给予克罗米芬加补佳乐治疗 ;人绝经期促性腺激素 (humanmenopausalgo nadotropin ,HMG)组 33例 ,给予HMG治疗 .利用超声波观察促排卵周期不孕症患者的子宫内膜厚度、类型、成熟卵泡数 ,妇科检查行宫颈评分 ,使用ELISA检测雌二醇 (estradiol,E2 )、孕激素 (progesterone,P)的浓度 ,进行比较 .结果 :CC +PGV组和HMG组在围排卵期子宫内膜厚度及宫颈评分分别为 (1 1 .8±2 .3)和 (1 1 .2± 1 .8)mm ,(1 0 .8± 0 .9)和 (1 0 .2± 1 .6 ) ,显著高于CC组 (8.2± 1 .2 )mm ,(8.7± 1 .5 ) (P <0 .0 1 ) ;3组子宫内膜类型 (A或B型 )比较无显著性差异 (P >0 .0 5 ) ;HMG组成熟卵泡数及黄体成熟期P浓度分别为 (5 .3± 1 .5 )和 (1 6 .7± 2 .4 )μg·L-1 ,明显高于CC组和CC +PGV组 [(3.9± 0 .8)和 (1 2 .9±0 .8) μg·L-1 ],[(3.1± 1 .7)和 (1 4 .6± 1 .7) μg·L-1 ](P <0 .0 1 ) ;HMG组E2 浓度为 (5 5 9± 1 87)ng·L-1 明显高于CC组 (1 89± 73)ng·L-1 、CC +PGV组 (2 2 6± 1 0 7)ng·L-1 (P     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Electro-Acupuncture Combined with the Trigger Point Needle-Embedding for Treatment of Primary Trigeminal Neuralgia in 31 Cases

In recent years, the author of this essay has applied electro-acupuncture combined with the trigger point needle-embedding for treatment of primary trigeminal neuralgia in 31 cases, yielding satis- factory results as reported in the following.     

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Objective： To explore the role of matrix metalloproteinase-1,2 （MMP-1, MMP-2） and tissue inhibitor of matrix metalloproteinases-1 （TIMP-1） in endometriosis. Methods： The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.endometria from 40 subjects （excluding endometriosis） were collected and examined by in situ hybridization technology and western blot assay. Results： Both expressions of MMP-1 and -2 were stronger in ectopic endometrium and eutopic endometrium than in normal endometrium. On the contrary, the expression of TIMP-1 in ectopic endometrium and eutopic endometrium was lower. The differences were significant （P 〈 0.01 ）. Moreover, there was no relationship among the expressions of MMP-1, 2 and TIMP-1 in ectopic endometrium. Conclusion： The expressions of MMP-1, 2 and TIMP-1 lose balance and lack of periodic changes in ectopic endometrium , which explains the biological invasive behavior of endometriosis. It was suggested-that regulating the balance between the MMPs and TIMP-1 should be an ideal therapeutic target to endometriosis.     

Shi Da-zhuo (史大卓) —An outstanding cardiologist of integrative medicine

Prof. SHI Da-zhuo, Ph.D., male, was born on March 20, 1960. Prof. SHI entered the Ph.D. program in 1990 at the China Academy of Chinese Medical Sciences under the supervision of Prof. CHEN Ke-ji, majoring in the treatment of cardiovascular diseases. After receiving his Ph.D. degree in 1993, Prof. SHI started working at the Cardiovascular Center in Xiyuan Hospital affiliated to China Academy of Chinese Medical sciences.     

Persist in and Carry Forward the Integrative Medical Research——Speech at the 6th National General Congress of Chinese Association of Integrative Medicine by Academician CHEN Zhu,Minister of Ministry of Health

The 6th National General Congress of Chinese Association of Integrative Medicine （CALM） was convened at 19-20, April 2008 in Beijing. Academician CHEN Zhu, the minister of Ministry of Health indicated at the congress that the integration of Chinese and Western medicine is very well in keeping with the situation of our country and the general rule of development in medical science; and as a good integration of Chinese medicine and Western medicine, it is mutually beneficial and advantageous to both of them. Seeing the creativity shown in integrative medical investigation in theoretic and methodological sides, we should and must persist in and develop it.