Efficacy of Getong Tongluo Capsule(葛酮通络胶嚢)for Convalescent-Phase of Ischemic Stroke and Primary Hypertension:A Multicenter,Randomized,Double-Blind,Controlled Trial

Objective:To evaluate whether the efficacy of Getong Tongluo Capsule(葛酮通络胶囊,GTC,consisted of total flavone of Radix Puerariae)on improving patients'quality of life and lowering blood pressure are superior to the extract of Ginkgo biloba(EGB)for patients with convalescent-phase ischemic stroke and primary hypertension.Methods:This randomized,positive-drug-and placebo-controlled,double-blind trial was conducted from September 2015 to October 2017.Totally 477 eligible patients from 18 hospitals in China were randomly assigned in a 2:1:1 ratio to the following interventions,twice a day for 12 weeks:(1)GTC 250 mg plus EGB-matching placebo 40 mg(237 cases,GTC group),(2)EGB 40 mg plus GTC-matching placebo 250 mg(120 cases,EGB group)or(3)GTC-matching placebo 250 mg plus EGB-matching placebo 40 mg(120 cases,placebo group).Moreover,all patients were orally administered aspirin enteric-coated tablets 100 mg,once a day fo r 12 weeks.The primary outcome was the Barthel Index(Bl).The secondary outcomes included the control rate of blood pressure and National Institutes of Health Stroke Scale(NIHSS)scores.The incidence and severity of adverse events(AEs)were calculated and assessed.Results:The Bl relative independence rates,the clinical recovery rates of NIHSS,and the total effective rates of NIHSS in the GTC and EGB groups were significantly higher than the placebo group at 12 weeks after treatment(P<0.05),and no statistical significance was found between the GTC and EGB groups(P>0.05).The control rate of blood pressure in the GTC group was significantly higher than the EGB and placebo groups at 12,18 and 24 weeks after treatment(P<0.01).There were no statistically significant differences in the incidences of AEs,adverse drug reactions,or serious AEs among the 3 groups(P>0.05).Conclusion:GTC exhibited significant efficacy in improving patients'quality of life as well as neurological function and controlling hypertension.     

抗震救灾中的传染病防治工作原则

人类的历史教训证明,包括大地震在内的严重自然灾害,对地域生态环境和人类居住条件造成极大的破坏,对灾区人员的健康造成沉重的打击.在这种情况下,发生重大传染病流行的风险将会显著增加.汶川大地震发生后,搜寻生还者,抢救伤病员是抗震救灾第一阶段的重点.     

A Bibliometrics Analysis on Academic Influence of Chinese Journal of Integrated Traditional and Western Medicine

Objective:To illustrate the academic influence of Chinese Journal of Integrated Traditional and Western medicine,and provide suggestions for further development of the Journal.Methods:Taking the China National Knowledge Infrastructure(CNKI)database as main source and the Chinese Science Citation Database(CSCD)as reference,the researchers retrieved the related data of the Journal such as its publication quantity,citations,fund projects,authors,institutions and regions from 1981 to 2018,analyzed these data by means of bibliometrics and information visualization with EXCEL,SPSS,VISIO,MATLAB and other softwares.Results:Through the analysis of the main indicators,the relevant indicators of the Journal’s academic influence revealed the developing trend of the Journal.Cardiovascular and cerebrovascular diseases,endocrine,digestive system,pharmacological research of Chinese medicine and gynecology,as the hot topics in the discipline and academic,were clarified.Conclusions:All indicators show that the Journal is a high-quality journal reflecting the excellent achievements in the field of integrated Chinese and Western medicine in China.Through further analysis of relevant indicators,the authors put forward some specific suggestions on how to run the Journal well.     

考试制度管理与改革之我见

分析目前考试制度存在的主要问题有命题、复习题、补考制度等方面的弊端,提出考试制度的改革要在加强"三风"建设、做好试题的编审工作、建立完善的考试管理制度、严肃补考纪律等方面下工夫,让严肃的考风带动良好的学风,从而提高教学质量.     

Vogt-小柳-原田综合征误诊1例报告

1临床资料 患者,男,29岁.入院前10d双眼视力突然下降,伴轻微头痛,曾就诊于其他医院,经眼科常规检查及眼部B超检查,诊断为原发性视网膜脱离,用药不详,因治疗效果不佳,于2002年10月18日来本院就诊.入院时自诉头痛明显,全身状况不佳,视力:右眼指数/1 m,左眼指数/1 m,双眼轻度睫状充血,角膜后可见细小点状沉着物,房水闪辉阳性,瞳孔呈药物性散大,直径5.5 mm,晶体不混浊,玻璃体可见条状混浊,眼压正常.     

婴幼儿游泳探讨

游泳是人类生活中最自然的生理活动和本能之一。不仅人类，哺乳动物也常有游泳行为，是生活中自然形成和掌握的一种本能。我们认为人和动物一样，生来就具有适应环境的能力。很多动物，无论大小都有游泳本领，不用谁来教，在水中通过多种姿势和划水方法，他们都会把鼻子露出水面，往岸上游。可是人类这种本能后来泯灭了。我们认为社会就是大海，人生就如在大海中游泳，从小让孩子在水中学会挣扎，锻炼拼搏精神，促进胎儿到婴幼儿神经及各脏器的持续发育，使生长的过程得到进一步、更高质量的发展，这对他们一生的好处都是不可估量的。     

头孢氨苄胶囊致过敏反应1例

1 临床资料 患者,男,66岁.因受凉后出现咳嗽、咯痰2d,其家属给予头孢氨苄胶囊0.5g口服后约10min后患者出现胸闷、心慌、呼吸困难、口唇紫绀,继而出现心悸出汗、全身无力、意识丧失、血压下降(60/30mmHg).医护人员迅速到达现场急救,立即给予吸氧、肌注肾上腺素1mg,静注地塞米松10mg,异丙嗪25mg,用药10min后病情好转,测血压80/60mmHg,1h后恢复正常.     

中国医药生物技术协会纳米生物技术分会批准成立大会在深圳召开

2007年12月31日,中国医药生物技术协会纳米生物技术分会批准成立大会在深圳市召开来自全国纳米生物技术领域的近百所大学、中科院研究所、医院、药厂、公司的院士、教授、主任医师、工程技术人员、企业主管出席了成立大会.会议由中国科学院姚开泰院士、中国工程院何继善院士、上海交通大学彭志海教授主持.复旦大学、北京大学、中南大学、清华大学、上海交通大学、四川大学、中山大学、浙江大学、中科院理化所、解放军总医院、石药集团、纳米生物技术公司等单位作了重要发言.     

国际心肺移植新进展——2006年第26届国际心肺移植协会年会报道

2006年4月5日至4月8日第26届国际心肺移植协会(ISHLT)年会在西班牙马德里隆重召开,来自全世界从事心肺移植的专家,包括心外科、胸外科、心内科、呼吸科、麻醉科、ICU、病理科、供体协调等从事基础及临床研究等相关科室的专家共2 000多人参加了此次盛会.     

东方大峡谷的民族医药之花——云南傈僳族医药简介

傈僳族是我国民族大家族中一个人数不多但却古老的成员.主要聚居在云南省怒江傈僳族自治州,在丽江和迪族、大理、保山、德宏、临沧等州县,以及四川省的盐源、盐边等县也有分布.根据2000年第5次全国人口普查统计,傈傈族人口数为634912.     

Neck

<正>210120 A single posterior surgical procedure for cervical spinal fracture combined with ankylosing spondylitis/Ji Hongquan(姬洪全,Dept Orthop,3rd Hosp Peking Univ,Beijing 100191)…Chin J Trauma.-2010,26(3).-213～216     

Neck

Effectiveness of anterior cervical microsurgicai decompression to treat spondylotic myelopathy;Analysis of veracity of the C1 lateral mass screw insertion in the atlantoaxial fixation     

Neck

<正>209509 Dianosis and surgical treatment of hyperectension cervical spine injury combined with intervertebral disk injury/Xu Zhaowan(徐兆万,Dept Spin Surg,Peop Hosp Weifang,Weifang 261041)…∥Chin J Traum.-2009,25(7). -594 ～597     

Neck

<正>209193 The role of MR T2image signal intensity and clinical manifestations in predicting prognosis for cervical ossification of the posterior longitudinal ligament/Shen Yong(Dept Spinal Surg,3rd Hosp Hebei Med Univ,Shijiazhuang 050051)…∥Chin J Orthop.-2009,29(3).-212~215Objective To investigate whether the signal intensity ratio on MRI and clinical manifestations can reflect prognosis in patients with cervical ossification of the posterior longitudinal ligament (OPLL).Methods From February 1999 to July 2007,58 patients with cervical OPLL were prospectively enrolled.They were treated with posterior decompression and followed up 1 to 7 years.1.5 T MRI was performed in all patients before surgery.T2 weighted images (T2WI) of sagital signal intensity on the cervical severe compression cord were obtained,and the regions of interest(ROIs) were taken by 0.05 cm2.T2WI of sagittal normal cord signal on the cervical between C7T1 disc levels were obtained,and the ROIs were taken by 0.3 cm2.Signal value was measured by computer and the signal ratio between regions of the 0.05 cm2 and 0.3 cm2 had been calculated.All of 58 patients have been divided into three groups with signal intensity ratio.Statistical analysis were performed.Results There were significant differences between three groups at the recovery rate,age,duration of disease,Babinski sign,ankle clonus,preoperative JOA score and postoperative JOA score.There was no significant differences at gender in three groups.And multiple linear regression showed that the recovery rate was correlated with age,Babinski sign,duration of disease and ankle clonus.     

颈围与代谢综合征

颈围是颈部喉结节点水平的围长,作为一个较新的评价肥胖的指标,其能较好地反映上半身皮下脂肪的分布。颈围与肥胖、血脂异常、高血压、胰岛素抵抗及睡眠呼吸暂停综合征密切相关,可作为代谢综合征的筛查指标。颈围的测量方法简单易行,且结果稳定可靠,是评价代谢综合征的最佳指标。     

改进功能性颈淋巴清扫术在头颈恶性肿瘤治疗中的应用

本文报道我科改进功能性颈淋巴清扫术107例，其中10例为双侧同期手术，获得满意效果．术式改进方法为将斜方肌上部前缘垂直切口设计呈“双曲”形，使术后伤口疤痕由直线收缩改为曲线收缩，进一步改善了颈部的外形及功能，术中采用胸锁乳突肌游离法，隧道式颈大块切除，保存了该肌的完整性，避免了术后肌肉僵硬萎缩；本组病例中89例保留了耳大神经，免除了患者耳廓及周围皮肤终生麻木的痛苦，并提出在实施功能性颈淋巴清扫术时应增加“4保留”原则，使这一术式更趋完善，以达到临床最佳效果．     

坐骨耻骨骨软骨病(Van Neck病)

目的:介绍和探讨坐骨耻骨骨软骨病(Ｖａｎ Ｎｅｃｋ病)的诊断和治疗．方法:回顾１３例ＶａｎＮｅｃｋ病患儿的临床经过和观察１００例４岁~１１岁儿童因其它原因所摄骨盆正位片．结果:１３例患儿均有坐耻骨结合处隆起和疼痛,Ｘ线检查显示坐耻骨结合处有局限性骨皮质膨隆,中央区透光,骨密度不均,无骨膜、软组织异常改变,其中２例在症状出现前５周~６周的Ｘ线片上已存在上述改变,经保守治疗全部治愈．１００例其它原因所摄骨盆片中有此改变１５例。结论:凡有上述Ｘ线改变的无论有无症状都应视为ＶａｎＮｅｃｋ病,本病预后良好,无须长期用药和手术．