两种术式治疗女性重度盆腔器官脱垂的疗效

目的比较prolift盆底重建系统与传统阴式子宫全切术及阴道前后壁修补术加骶棘韧带悬吊术治疗女性重度盆腔器官脱垂的应用效果。方法回顾分析该院2009年1月至2011年9月治疗患有POP-Q分期Ⅲ～Ⅴ期的患者30例,其中采用prolift盆底重建术14例,其他患者采用传统术式,比较两组患者的手术效果、术后并发症、手术情况(手术时间及出血量),并进行统计学分析。结果 Prolift组手术时间及出血量明显少于阴式子宫全切术及阴道前后壁修补术加骶棘韧带悬吊术组(P<0.05),POP-Q分期评价两组患者术后阴道Aa、Ba、C、Ap、Bp位点均得到显著改善,解剖疗效明显。结论两种术式应用于纠正女性重度盆腔器官脱垂都是安全可行的,但术后复发率、手术时间、手术出血量、手术并发症等方面,pro-lift盆底重建系统优于传统阴式子宫全切术加阴道前后壁修补术及骶棘韧带悬吊术。     

改良盆底重建术治疗盆腔脏器脱垂疗效观察

目的观察改良盆底重建术治疗盆腔脏器脱垂的疗效。方法50例盆腔器官脱垂患者,随机分为对照组和观察组各25例。对照组采用传统盆底重建术,观察组行改良盆底重建术。结果两组患者手术顺利。观察组阴道前壁脱垂全部得到纠正;随访1a均未出现复发;未见手术并发症。对照组6例复发,2例发生尿潴留,2例阴道聚丙烯补片修补术后发生侵蚀。观察组保留尿管时间和平均住院天数均明显少于对照组（P均〈0．05）。结论改良盆底重建术治疗盆腔脏器脱垂安全有效。     

全盆底网片悬吊术治疗老年妇女盆腔器官脱垂疗效观察

目的观察全盆底网片悬吊术治疗老年妇女盆腔器官脱垂（POP）的疗效。方法对15例同时伴有子宫（穹窿）、阴道前后壁脱垂的POP患者行全盆底网片悬吊术治疗。结果 15例患者手术顺利,手术时间68～150min,术中出血量150～500 ml,无输血病例,无直肠及膀胱损伤。住院时间5～9 d。术后随访1～18个月,盆底结构正常,POP均未复发。4例器官脱垂症状改善,5例腰骶部不适消失,9例便秘消失,11例压力性尿失禁治愈。术后发生网片侵蚀伴阴道分泌物增多症状1例,修剪侵蚀的网片后恢复正常。结论全盆底网片悬吊术治疗老年妇女POP能实现全盆底解剖和功能重建,近期疗效较好。     

人工合成补片在全盆底重建手术中的应用

目的探讨人工合成补片应用于全盆底重建手术(TPMR)的可行性及有效性。方法将116例盆底器官脱垂(POP)患者分为观察组和对照组。观察组80例在阴道前壁或后壁置入不可吸收的聚丙烯网片,对照组36例采用传统的盆底重建手术。每组分为37～59岁组和60～73岁组。根据国际尿控协会制定的POP定量(POP-Q)分度法评价手术效果。疗效评定以术后无阴道壁脱垂为治愈,生活质量评定以PFDI-20短表为标准,随访3～30个月。结果观察组80例患者手术时间平均为120～150min,术中出血平均为158ml。患者术后恢复良好,住院时间平均7d。术后随访3～30个月均无阴道壁膨出,4例网片侵蚀阴道黏膜,1例术后排尿困难,患者均无膀胱尿道及直肠并发症。术后生活质量评定观察组明显高于对照组。观察组复发率明显低于对照组(P0.05),60～73年龄组复发率明显高于37～59年龄组(P0.05)。结论网片用于中老年妇女阴道前后壁膨出、膀胱膨出、直肠膨出的疗效优于传统的盆底重建术,手术复发率低。长期效果有待进一步观察。     

阴道后壁“桥式”修补结合盆底筋膜缝合治疗阴道后壁缺陷临床分析

目的探讨阴道后壁＂桥式＂修补结合盆底筋膜缝合治疗阴道后壁缺陷的临床疗效。方法回顾性分析我院行阴道后壁＂桥式＂修补结合盆底筋膜缝合术患者83例,比较手术前后盆腔器官脱垂定量（POP-Q）分度的变化,以了解术后患者的盆底解剖学恢复情况,通过观察患者排便情况评价患者手术前后排便功能失调的改善情况,通过盆腔器官脱垂-尿失禁患者性生活调查问卷（PISQ-12）评价患者手术前后的性生活质量。结果单纯行＂桥式＂缝合的平均手术时间15 min,无手术并发症。术后1例后壁膨出复发,复发率为1.2%,术后排便症状改善率为81.2%,性交痛的发生率为2.63%,PISQ-12评分术前（79.57&#177;6.56）分,术后（78.62&#177;6.40）分,手术前后比较差异无显著性。结论阴道后壁＂桥式＂修补近期疗效确切,能改善部分患者的便秘症状,对患者性生活质量也无明显影响。     

盆底重建术治疗老年妇女子宫脱垂的疗效及对病人生活质量的影响

目的观察盆底重建术治疗老年妇女子宫脱垂的疗效,并探讨其对病人生活质量的影响。方法将116例子宫脱垂老年病人随机分为观察组和对照组,每组58例;观察组病人采用盆底重建术进行治疗,对照组病人采用阴式子宫切除联合阴道前后壁修补术进行治疗。比较2组在手术情况、治疗效果及生活质量方面的差异。结果观察组的手术时间、术中出血量及住院时间均明显优于对照组(P0.05);治疗后,观察组盆腔器官脱垂定量(POP-Q)各指示点测量值的改善程度均较对照组更显著(P0.05);术后3个月、6个月、1年时,观察组的盆底障碍影响简易问卷7(PFIQ-7)评分均较治疗前显著降低,且明显低于对照组相同时间点(P0.05);术后1年,观察组的复发率(0)明显低于对照组(10.34%)(P0.05),但2组术后并发症发生率差异无统计学意义(P0.05)。结论盆底重建术治疗老年子宫脱垂疗效显著,术后复发率低,且其对病人生活质量的改善效果优于阴式子宫切除联合阴道前后壁修补术。     

应用全盆底重建术治疗老年女性重度盆腔器官脱垂临床分析

目的 评价全盆底重建术治疗老年女性重度盆腔器官脱垂的疗效.方法 回顾性分析34例POP-QⅢ～Ⅳ期盆腔器官脱垂行全盆底重建术的老年患者临床资料,评价该手术疗效及对患者生活质量的影响.结果 所有手术均安全顺利进行,未见膀胱、直肠等损伤;手术时间（105±31.2） min,出血（185.4±65.9） mL;所有患者术后4～5d后均自主排尿.随访2年,复发率为0（0/34）;PFIQ评分由术前的（84.3±22.6）分降至术后2年的（11.2±6.5）分,PFDI评分由术前的（75.8±19.4）分降至术后2年的（12.4±5.3）分.结论 全盆底重建术用于纠正老年女性重度盆腔器官脱垂,手术安全,术后生活质量改善明显,值得临床推广应用.     

全盆底重建术与传统阴式手术治疗盆腔器官脱垂的疗效及安全性评价

目的 评价全盆底重建术与传统阴式手术治疗盆腔器官脱垂的疗效及安全性.方法 计算机检索PubMed、HighWire、EMbase、VIP、CNKI、万方数据库、中国生物医学文献数据库、西文生物医学期刊文献数据库,纳入盆底重建术与传统阴式手术治疗盆腔器官脱垂的随机对照试验（RCT）研究.对纳入的RCT研究进行质量评价,采用RevMan 5.1软件进行Meta分析.结果 纳入RCT研究10个（10篇文献）,共计706例受试者.与传统阴式手术治疗者相比,盆底重建术患者的手术时间短、术中出血量少、排气时间短、住院时间短（P均＜0.05）,且复发率低（P＜0.01）.结论 相对于传统阴式手术,全盆底重建术治疗盆底器官脱垂疗效好且安全.     

Prolift盆底重建术治疗老年重度盆腔器官脱垂的临床分析

目的研究Prolift盆底重建术在老年重度盆腔器官脱垂(pelvic organ prolapse,POP)患者中的临床应用价值,为治疗该病症提供方法。方法回顾性分析2015年3月-2019年3月于本院接受住院治疗的87例重度POP患者临床资料,按治疗方法差异分为观察组(n=44)和对照组(n=43)。观察组采取Prolift盆底重建术治疗,对照组采取传统阴式子宫切除术及阴道前后壁修补术治疗。评估并比较2组手术指标、术前及术后盆底肌力、生活质量、术后并发症和复发情况。结果观察组的手术时间明显短于对照组,术中出血量明显少于对照组,术后残余尿量明显多于对照组,差异均有统计学意义(P<0.05)。观察组患者术后1年的盆底肌静态张力、动态张力及收缩力均比同组术前及对照组术后1年升高(P<0.05),而2组术后1年肌电位差异无统计学意义(P>0.05)。术后1年时,2组各项生活质量评分均较同组术前显著降低(P<0.05),而观察组评分均显著低于对照组(P<0.05)。观察组术后并发症发生率及术后复发率均明显低于对照组(P<0.05)。结论Polifl盆底重建术可治疗老年重度POP,疗效确切,创伤小,安全性高;在保留子宫的同时,可完成盆底结构重建,促进盆底肌肉功能的恢复,是治疗老年POP的有效方法。     

全盆底重建术治疗老年妇女子宫或阴道脱垂的临床研究

女性盆底功能障碍性疾病（pelvic floor dysfunction,PFD）是由于各种原因所致支持盆底组织的结缔组织或韧带损伤,进而盆腔脏器移位引发其他盆腔内器官的位置和功能异常的一类疾病。近年来基于吊床理论的盆底重建手术为这一类疾病的治疗带来了新的视角,已有研究显示术后复发率显著降低,但随之而来的新的手术并发症也备受关注。本研究旨在探讨全盆底重建术治疗老年妇女子宫或阴道脱垂的临床疗效。     

Pelvic organ prolapse: a review

Pelvic organ prolapse is a common medical problem in parous women. This condition usually refers to a combination of deficiencies of the pelvic organs as they relate to support mechanisms of the vaginal wall. Symptoms vary--an accurate diagnosis requires a careful and complete physical examination with attention directed toward the pelvis and perineum. Although many patients will not require surgical treatment for pelvic organ prolapse, a comprehensive approach to repair in which all of the anatomic defects affecting support are addressed is necessary for successful treatment. Patients presenting with pelvic organ prolapse often provide some of the most complex, challenging, and rewarding cases in reconstructive pelvic surgery. This article addresses the definitions and classifications, prevalence and risk factors, and anatomy and pathophysiology relevant to pelvic organ prolapse. Discussion also includes diagnosis and approaches to management (surgical and nonsurgical) of anterior vaginal wall prolapse, cystourethrocele, apical vaginal prolapse, uterine prolapse and enterocele, posterior vaginal wall prolapse, rectocele, and pelvic floor relaxation and perineal laxity, with indications for and approaches to surgery, along with possible complications.     

阴道全封闭术治疗老年女性盆腔器官脱垂的疗效

目的 分析老年女性盆腔器官脱垂(POP)患者实施阴道全封闭术的临床疗效及安全性.方法 选取2012年1月至2018年1月在佛山市妇幼保健院妇科住院治疗、盆腔器官脱垂分期法(POP-Q)评定为Ⅲ～Ⅳ期、并接受阴道全封闭术治疗的78例老年POP患者.所有患者治疗后进行1年随访观察,记录术前和术后POP-Q分期情况.分析患者...     

A critical review of mesh kits for prolapse repairs

Demographic trends in the United States clearly indicate an aging population; therefore, a steady percentage of women with pelvic floor dysfunction suggests that ever-increasing numbers of women will seek treatment for conditions such as pelvic prolapse. Surgical techniques have rapidly evolved in recent years to include multiple proprietary kits that purport to facilitate repair using synthetic graft implants in minimally invasive fashion. Most of these products have entered the market so quickly that scientific literature lags behind with evidence to document safety and efficacy. We initially intended to examine recent publications on surgical kits for pelvic prolapse repair, but realized that, although numerous clinicians are collecting data and publishing sporadically, most information is now only available in abstract form. Therefore, this article focuses on the Apogee and Perigee systems (American Medical Systems, Minnetonka, MN), Avaulta (Bard Urological, Covington, GA), Gynecare Prolift (Ethicon, Somerville, NJ), and USS Posterior Intravaginal Slingplasty system (Tyco Healthcare, US Surgical, Norwalk, CT).     

Augmented repairs and use of interposition grafts in pelvic reconstructive surgery: Part I

Because the prevalence of pelvic organ prolapse increases with age and the number of women aged 65 years and older is expected to double in the next 25 years, demand is increasing for subspecialty services related to pelvic floor disorders. Synthetic and biologic interposition grafts have been proposed as a way of augmenting weakened host tissues during pelvic reconstructive surgical procedures because the rate of recurrent pelvic organ prolapse is unacceptably high. Although graft use is rapidly increasing among pelvic reconstructive surgeons, the role of prosthetics is controversial and currently in the process of evolution, with few evidence-based data to support their routine use. This review provides a context for the use of prosthetic grafts in pelvic reconstructive surgery, discusses the properties of both synthetic and biologic materials commonly used during transvaginal reconstructive procedures, and reviews the literature with respect to the role of graft interposition during anterior compartment prolapse repair.     

Rectal prolapse and anal incontinence treated with a modified Roscoe Graham operation

The results of abdominal mobilization of the rectum and repair of the pelvic floor behind the anorectal junction are reported in 23 patients with rectal prolapse, being accompanied by some form of anal incontinence in 12. Within 20 months, on the average, three patients had recurrent prolapse. Two thirds of the patients with incontinence for solid and/or fluid feces were cured for prolapse as well as incontinence. Seven became constipated, while 14 were fully satisfied. Seven of eight patients with a highly reduced tone of the external sphincter before surgery had a marked improvement after surgery. The results do not differ greatly from those after the suspension operation or repair of the pelvic floor in front of the rectum, despite being more physiologic, but suggest that simultaneous suspension and abdominal repair of the pelvic floor may avoid the need for a secondary postanal repair from below in patients with persistent incontinence after suspension surgery. A controlled, randomized trial is advocated.     

全骨盆底悬吊术在女性骨盆底功能重建中的应用

目的探讨利用全骨盆底网片悬吊术治疗女性盆腔脏器脱垂并进行骨盆底重建的可行性和有效性。方法对2005年1月至2006年6月确诊为盆腔脏器脱垂的53例患者采用蝶形聚丙烯网片进行经阴道全骨盆底悬吊术,根据临床检查及主诉对手术前后脱垂情况进行评估,观察疗效并定期随访。结果手术时间平均97min,出血量平均160ml,53例均在术后2～6d出院,术后1、3、9、12个月随访,根据国际尿控协会制定的盆腔脏器脱垂定量分度法客观评估子宫脱垂、阴道前后壁膨出等症状全部得到纠正,无复发、无阴道扭曲和缩短、无性生活障碍,满意度达94．3％。结论全骨盆底网片悬吊术是经阴道的微创手术,对盆腔脏器脱垂患者在保留子宫的同时进行骨盆底功能重建,复发率低,值得临床进一步推广。     

Vaginal Prolapse Repair—Native Tissue Repair versus Mesh Augmentation: Newer Isn’t Always Better

The purpose of this article is to update the female urology and urogynecologic community on the controversy regarding approaches to vaginal surgery for pelvic organ prolapse. We will review the salient issues in traditional, vaginal native-tissue (NT) repair for pelvic organ prolapse. We intend to provide arguments advocating vaginal NT repair over that of vaginal mesh-augmented (MA) repair, and to show that newer is not always better.     

Dynamic pelvic magnetic resonance imaging and cystocolpoproctography alter surgical management of pelvic floor disorders

PURPOSE: Pelvic organ prolapse results in a spectrum of progressively disabling disorders. Despite attempts to standardize the clinical examination, a variety of imaging techniques are used. The purpose of this study was to evaluate dynamic pelvic magnetic resonance imaging and dynamic cystocolpoproctography in the surgical management of females with complex pelvic floor disorders. METHODS: Twenty-two patients were identified from The Johns Hopkins Pelvic Floor Disorders Center database who had symptoms of complex pelvic organ prolapse and underwent dynamic magnetic resonance, dynamic cystocolpoproctography, and subsequent multidisciplinary review and operative repair. RESULTS: The mean age of the study group was 58 ± 13 years, and all patients were Caucasian. Constipation (95.5 percent), urinary incontinence (77.3 percent), complaints of incomplete fecal evacuation (59.1 percent), and bulging vaginal tissues (54.4 percent) were the most common complaints on presentation. All patients had multiple complaints with a median number of 4 symptoms (range, 2–8). Physical examination, dynamic magnetic resonance imaging, and dynamic cystocolpoproctography were concordant for rectocele, enterocele, cystocele, and perineal descent in only 41 percent of patients. Dynamic imaging lead to changes in the initial operative plan in 41 percent of patients. Dynamic magnetic resonance was the only modality that identified levator ani hernias. Dynamic cystocolpoproctography identified sigmoidoceles and internal rectal prolapse more often than physical examination or dynamic magnetic resonance. CONCLUSIONS: Levator ani hernias are often missed by physical examination and traditional fluoroscopic imaging. Dynamic magnetic resonance and cystocolpoproctography are complementary studies to the physical examination that may alter the surgical management of females with complex pelvic floor disorders.Presented at the meeting of The American Society of Colon and Rectal Surgeons, Boston, Massachusetts, June 24 to 29, 2000.No reprints are available.     

Total uterine prolapse complicated with vesicovaginal fistula: A case report

Rationale:Vesicovaginal fistula (VVF) most commonly occurs due to iatrogenic injury during surgery or obstructed labor. We report a rare case of a patient with severe pelvic organ prolapse who developed VVF even though pessary had not been used.Patient concerns:A 63-year-old postmenopausal woman, para 3 (all spontaneous vaginal deliveries), complained of vaginal bulging sensation and involuntary urinary leakage for 3 years.Diagnosis:Stage IV uterine prolapse with VVF.Interventions:She underwent transvaginal VVF repair combined with total vaginal hysterectomy and sacrospinous ligament fixation. The postoperative course was uncomplicated.Outcomes:The patient remained free of complications during the 1-year follow-up.Lessons:This case illustrates the point that patients with pelvic organ prolapse (POP) should be treated promptly and careful follow-up should be conducted. Clinicians should be aware of the symptoms of VVF to ensure its early diagnosis and treatment.     

Acupoint injection combined with pelvic floor rehabilitation in the treatment of postpartum pelvic floor disorders: A protocol of randomized controlled trial

Background:Female pelvic floor dysfunction is one of the common chronic diseases affecting women''s physical and mental health. Pregnancy and delivery are one of the main causes. Pelvic floor rehabilitation is a common method for the treatment of postpartum pelvic floor dysfunction, but it has some defects. Acupoint injection has advantages in the treatment of postpartum pelvic floor dysfunction, but there is a lack of standard clinical research to verify it. Therefore, the purpose of this randomized controlled trial is to evaluate the efficacy and safety of acupoint injection combined with pelvic floor rehabilitation in the treatment of postpartum pelvic floor disorders.Methods:This is a prospective randomized controlled trial to study the efficacy and safety of acupoints injection combined with pelvic floor rehabilitation. And it is approved by the Ethics Committee of Clinical Research of our hospital. Patients were randomly divided into observation group (acupoint injection combined with pelvic floor rehabilitation group) or control group (pelvic floor rehabilitation group alone). The patients were followed up for 8 weeks after 12 weeks of treatment. The observation indexes included: pelvic organ prolapse degree, pelvic floor muscle strength, urinary incontinence score, adverse reactions, among others. Data were analyzed using the statistical software package SPSS version 18.0.Conclusions:This study will evaluate the efficacy and safety of acupoint injection combined with pelvic floor rehabilitation in the treatment of postpartum pelvic floor dysfunction, and provide reliable reference for the clinical application of this project.Trial registration:OSF Registration number: DOI 10.17605/OSF.IO/VC65Z