Q开关Nd：YAG激光治疗蓝黑纹身114例疗效观察

我科于1999年2月～2000年6月应用伊曲康唑治愈由化疗诱发的糠秕孢子菌毛囊炎5例,现报告如下。临床资料：5例患者均为男性,年龄34～48岁,均经组织病理学检查确诊为癌症患者,5例均住院化疗4～6个疗程,于化疗后均于胸、背、颈部出现红色毛囊性炎性丘疹,予以抗过敏抗炎治疗后,皮疹增加,转至我科治疗,查体：5例患者的胸、背、颈部均有玫瑰红色炎性丘疹,部分丘疹中间有脓疱,个别患者皮肤油腻现象严重。实验室检查：刮取毛囊顶端脓疱液滴于10％氢氧化钾玻片上直接涂片后均找见圆形孢子或菌丝,诊断：糠秕孢子菌毛囊炎。治疗：5例患者均…     

Q开关Nd:YAG激光治疗错误文眉103例疗效观察

目的:观察Q型YAG激光祛除错误文眉的疗效.方法:选用波长1.064μm,工作电压340～400V,调Q脉冲式Nd:YAG激光机治疗103例错误文眉.结果:痊愈83例,占80.58%;显效18例,占17.48%;有效2例,占1.94%;总有效率98%.结论:应用Q型YAG 1.064μm波长祛除错误文眉,疗效满意,不留疤痕,是目前祛除错误文眉的安全、高效方法.     

Q开关Nd:YAG激光治疗雀斑样痣疗效观察

目的:评价波光为532 nm的Q开关Nd:YAG激光对单纯性雀斑样痣的疗效。方法:用Q开关Nd:YAG激光(532 mn,光斑直径2-3 mm,频率5 Hz)治疗26例单纯性雀斑样痣患者,治疗前后相对比进行评价,并观察不良反应。结果:26例患者治疗1-3次,治疗间隔为2-3月。基本治愈率为50%,有效率为61.5%。结论:单纯性雀斑样痣患者用Q开关532 nm Nd:YAG激光安全而有效。     

Q开关Nd:YAG激光治疗双侧太田痣3例

报告3例双侧太田痣。患者均为女性,1例为早发型,2例为迟发型。皮损特点是蓝褐色斑疹,主要累及巩膜及受三叉神经支配的面部皮肤,无自觉不适。其中1例患者父亲及妹妹均患此病。予Q开关Nd:YAG激光(波长1064nm)治疗,疗效满意。     

Q开关Nd:YAG激光治疗色素增加性皮肤病疗效分析

目的观察Q开关Nd:YAG激光治疗色素增加性皮肤病的临床疗效及治疗次数、间隔时间以及安全性。方法用Q开关Nd:YAG激光(1 064 nm,532 nm波长)治疗570例色素增加性皮肤病,观察、分析其疗效。结果 Q开关Nd:YAG激光治疗色素增加性皮肤病均有效。其中老年斑、雀斑、蓝黑纹身、雀斑样痣、褐青色痣、太田痣总有效率均达87.14%以上。黄褐斑总有效率为85.20%。咖啡斑、炎症后色素沉着总有效率分别为65.00%及60.00%。毛表皮痣总有效率为30.00%。痊愈率由高到低依次为老年斑、雀斑、雀斑样痣、蓝黑纹身、褐青色痣、太田痣、黄褐斑、咖啡斑、炎症后色素沉着、毛表皮痣。治疗次数1～13次,间隔时间1周～半年。临床疗效与治疗次数呈正相关,不良反应少。结论Q开关Nd:YAG激光治疗色素增加性皮肤病的疗效显著,安全性较好。毛表皮痣治疗效果相对较差。     

Q开关Nd:YAG激光治疗太田痣体会

Q开关Nd:YAG激光治疗太田痣已在临床广泛开展,我科自1997年12月以来开展该疗法,现就治疗体会总结如下。1临床资料     

Q开关Nd:YAG激光治疗颧部褐青色痣的疗效分析

目的 探讨Q开关Nd:YAG激光治疗颧部褐青色痣的临床疗效.方法 应用Q开关Nd:YAG激光治疗仪,治疗波长为1064nm,光斑直径2～4mm,能量密度3.0～4.0J/cm2,脉宽10ns.结果 72例患者经治疗1～5次,间隔时间3～12个月,共治愈28例(38.9%),总有效率100%,疗效与治疗次数成正相关.术后色素沉着47例(65.3%).结论 Q开关Nd:YAG激光疗效确切,是治疗颧部褐青色痣的理想方法之一.     

Q开关Nd:YAG激光联合咪喹莫特乳膏治疗扁平疣的疗效观察

目的观察Q开关Nd:YAG激光联合咪喹莫特乳膏治疗面部扁平疣的临床疗效。方法将62例扁平疣患者随机分成治疗组(32例)和对照组(30例),治疗组使用Q开关532 nm Nd:YAG激光治疗,后期外用喹莫特乳膏,对照组单外用咪喹莫特乳膏,观察疗效。结果治疗组的痊愈率为78.1%,总有效率为96.9%,对照组的痊愈率为46.7%,总有效率为76.7%,2组疗效差异均有统计学意义(P0.01)。结论 Q开关Nd:YAG联合咪喹莫特乳膏治疗扁平疣疗效好,值得临床推广。     

Q开关Nd:YAG激光联合红花逍遥片治疗黄褐斑临床观察

目的探讨Q开关Nd:YAG激光联合红花逍遥片治疗黄褐斑的疗效和安全性。方法将210例黄褐斑患者随机分为3组,每组各70例。治疗组予Q开关Nd:YAG激光治疗联合红花逍遥片口服;对照1组单纯予Q开关Nd:YAG激光治疗;对照2组单纯口服红花逍遥片。Q开关Nd:YAG激光治疗每周1次连续10周,后2周1次再治疗6周,共16周。红花逍遥片口服2片,3次/d连续16周。分别于5,10和16周时评价临床疗效。结果 16周时治疗组有效率为90.00%,对照1组为80.00%,对照2组为41.00%,差异有统计学意义(P均0.01);治疗组不良反应发生率为26.00%,对照1组为21.00%,对照2组为17.00%,差异无统计学意义(P0.05)。结论 Q开关Nd:YAG激光联合红花逍遥片治疗黄褐斑比两者单独应用效果好。     

Q-开关Nd:YAG激光治疗扁平疣72例疗效观察

笔者于1999年11月～2001年12月采用Q-开关Nd:YAG激光治疗扁平疣72例,取得满意效果,现报告如下。1病例与方法病例选择:72例扁平疣患者均为笔者所在医院门诊患者,其中男26例,女46例,年龄8～35岁,病程均>半年,皮疹数目在50枚以上,分布以面部为主。所有患者既往接受过3种以上的治疗,未见好转,皮疹数目不减少或仍在增多。治疗方法:所有患者均采用Q-开关Nd:YAG激光机(MedliteⅣ)治疗,治疗前照相作为评价资料。对于小儿或对痛觉敏感者,治疗前1h于病变部位涂表面麻醉药膏(5%ELMA,Sweden),常规消毒。激光治疗参数设定:波长532nm,光斑2mm,频率5…     

Q‐switched Nd:YAG laser for cosmetic tattoo removal

Laser is a widely accepted tool for tattoo removal, with standardized treatment protocols. Nevertheless, cosmetic tattoo removal may be challenging, because tattoos are performed in proximity of “sensitive” areas and because the ink used in cosmetic tattoos may contain substances that are not standardized and may modify their color at a high temperature. In this case series, we aim to evaluate the effectiveness of Q‐switched (QS) Nd:YAG laser for cosmetic tattoo removal. Our study included 20 patients with cosmetic tattoos of lips, eyebrows, and eyeliners treated with QS Nd:YAG laser. Before treatment, an accurate preoperative assessment was performed, taking into account both patient and tattoo characteristics. Complete tattoo removal was obtained in all the cases and no major complications occurred. Adverse events were mild, mostly represented by erythema. All patients reported a high level of satisfaction. Selective photothermolysis enables complete tattoo removal, even in the case of cosmetic tattoos. However, cosmetic tattoos require a personalized treatment based on an accurate preoperative assessment which takes into account both patient and tattoo characteristics. QS Nd:YAG laser may be considered a good choice in the treatment of cosmetic tattoos, because it enables complete removal with acceptable secondary effects.     

A rapid tattoo removal technique using a combination of pulsed Er:YAG and Q-Switched Nd:YAG in a split lesion protocol

Background: Tattoo removal has evolved over the years and though Q-switched laser is the ‘workhorse’ laser, it invariably requires multiple sittings, which are dependent on numerous factors, including the skin colour, location of the tattoo, age of the tattoo, colour of pigment used, associated fibrosis and the kind of tattoo treated. Though ablative lasers, both pulsed CO2 and Er:YAG, have been used for recalcitrant tattoos, very few studies have been done comparing them with pigment-specific lasers. Our study was based on the premise that ablating the epidermis overlying the tattoo pigment with Er:YAG could help in gaining better access to the pigment which would enable the Q-switched laser to work effectively with less beam scattering. Objective: A study of rapid tattoo removal (RTR) technique using a combination of pulsed Er:YAG and Q-Switched Nd:YAG in a split lesion protocol. Materials and methods: This prospective study was undertaken during 2010–13 at a laser Clinic in the Maulana Azad Medical College, New Delhi. A total of 10 patients were recruited, 5 of amateur tattoo and 5 of professional tattoo. After informed consent each tattoo was arbitrarily ‘split’ into two parts. One part was treated with QS Nd:YAG laser(1064 nm) and the other part with Er:YAG laser immediately followed by the QS Nd:YAG. The laser treatments were repeated at 6-week intervals until the tattoo pigment had cleared. On the combination side in subsequent sittings only the QS Nd:YAG was used, to minimize repetitive ablation. To ensure consistency in the intervention methods a trained dermatologist who was independent of the treatment delivery randomly rated 10% of the procedures. Results: The mean improvement achieved by the Q-switched laser (2.93) was less than the combination laser (3.85) side (p = 0.001) and needed more sessions (3.8 vs. 1.6; p = 0.001). There was a statistically significant difference in the improvement on the combination side till the second session. On the combination side patients required a maximum of 2 sessions, while the Q-switched laser required 3–5 sessions for appreciable lightening. Conclusion: From our study it was concluded that use of a pulsed ablative laser may help in rapid removal of tattoos in conjunction with QS lasers with minimal side effects and can be used as a RTR.     

Red ink tattoo reactions: successful treatment with the Q-switched 532 nm Nd:YAG laser

BACKGROUND: In the South-west Thames region there were an unprecedented number of lichenoid tattoo reactions to red ink in patients who had visited a local tattoo parlour. The red ink was found to contain mercuric sulphide, a compound known to cause allergic reactions. Topical Dermovate (clobetasol propionate 0.05%, GlaxoWellcome) ointment alone had little impact. OBJECTIVES: To investigate whether the Q-switched 532 nm Nd:YAG laser could produce permanent flattening of the reaction. METHODS: This was an open nonrandomized clinical trial. Biopsies were taken from the lichenoid areas within the tattoos. Subjects were patch tested to 1% ammoniated mercury in petrolatum prior to treatment with the Q-switched 532 nm Nd:YAG laser. Laser treatments were delivered at 6-weekly intervals by a single operator. Patients also applied topical Dermovate between treatments. Therapy was discontinued when the lesions flattened. Clinical photographs were assessed at baseline and prior to each laser treatment. RESULTS: Seven patients with Fitzpatrick skin types I-III were enrolled in the study (four females, three males, mean age 39 years). All patients completed the trial. Patch testing to mercury was universally negative at 48 and 96 h. Substantial flattening and depigmentation of the red ink within the tattoos was noted after six laser treatments. No adverse effects were recorded. CONCLUSIONS: The Q-switched 532 nm Nd:YAG laser in combination with topical Dermovate ointment is a safe and effective method of treating red ink tattoo reactions.     

Combination of CO2 and Q-switched Nd:YAG lasers is more effective than Q-switched Nd:YAG laser alone for eyebrow tattoo removal

Background: The eyebrow tattoo removal using Q-switched lasers is usually prolonged. Other modalities may be required to enhance the efficacy and shorten the treatment course. Objective: To compare the efficacy of Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser alone versus combination of Q-switched Nd:YAG and Ultrapulse CO₂ lasers for eyebrow tattoo removal after a single session. Patients and methods: After local anesthesia, the right eyebrow of 20 patients was treated with Ultrapulse CO₂ laser with the parameters of 4 J/cm² and 3.2 J/cm² for the first and the second passes. Both eyebrows were then treated with 1064-nm and 532-nm Q-switched Nd:YAG laser. The spot size and pulse duration were 3 mm and 5 nanoseconds for both wavelengths, and the fluence was 7 J/cm² for 1064 nm and 3 J/cm ² for 532 nm. Results: The side treated with combination of Q-switched Nd:YAG and CO₂ lasers improved 75–100% in 6 of 20 patients versus only 1 of 20 in the side treated with Q-switched Nd:YAG alone. Similarly, the right side in 13 of 20 patients showed more than 50% improvement with combination therapy versus the left side (the monotherapy side), where only 6 of 20 cases showed more than 50% improvement. The Mann–Whitney test was 2.85 for the right side and 1.95 for the left side (P value = 0.007). Conclusion: Using Ultra pulse CO₂ laser enhances the efficacy of Q-switched Nd:YAG laser in eyebrow tattoo removal.     

Lichen sclerosus associated with Nd:YAG laser therapy

Laser is the most efficient and popular method in hair removal. The most common side effects of laser assisted hair removal are pain, erythema, edema, hypopigmentation, hyperpigmentation, blistering, crusting, erosions, purpura, folliculitis, and scar formation (1 Nanni CA, Alster TS. Laser-assisted hair removal: side effects of Q-switched Nd: YAG, long-pulsed ruby, and alexandrite lasers. J Am Acad Dermatol. 1999;41(2 Pt 1):165–71. doi:10.1016/S0190-9622(99)70043-5.[Crossref], [PubMed], [Web of Science ®] , [Google Scholar]). Herein, for the first time we describe a case of lichen sclerosus (LS) following hair removal with long pulsed 1064 nm Nd:YAG laser therapy.     

Comparison of Q-switched Nd:YAG laser alone versus its combination with ultrapulse CO2 laser for the treatment of black tattoo

Background: Q-switched lasers are conventionally used for the treatment of black tattoo. However, they require multiple sittings, and the response may be slow due to competing epidermal pigment in dark skin. Objective: To compare the efficacy of Q-switched Nd:YAG laser alone with its combination with ultrapulse CO₂ for the removal of black tattoo. Materials and methods: Sixty patients with black tattoo were randomized into two groups viz., group A and group B. Group A was treated with QS Nd:YAG laser (1064 nm) alone, and group B received combination of ablative ultrapulse CO₂ followed by fixed-dose QS Nd:YAG laser (1064 nm), at 6-week interval for a maximum of 6 sittings. After each sitting, 3 independent physicians noted percentage of improvement that was evaluated using visual analogue scale (VAS) and grading system for tattoo ink lightening (TIL). Results: Combination laser (group B) showed statistically significant improvement in mean VAS score in the last 2 noted visits as compared to 1st session (p < 0.007, p < 0.001) and TIL mean score in last three noted visits as compared to 1st session (p < 0.008, p < 0.020, and p < 0.004). There was no statistically significant difference in the side effect profile of both the groups. Conclusion: For refractory professional tattoos, combination of ultrapulse CO₂ laser and QS Nd:YAG laser is superior to QS Nd:YAG laser alone.     

Q开关Nd:YAG激光1064nm联合532nm波长治疗颧部褐青色痣临床观察

目的 观察Q开关Nd:YAG激光1064 nm联合532 nm波长治疗颧部褐青色痣的临床疗效及不良反应.方法 应用Q开关Nd:YAG激光1064 nm联合532 nm波长治疗70例患者,开始选择波长为1064 nm,光斑直径3～4 mm,能量密度3.5 ～ 4.5 J/cm2,频率10 Hz,脉宽10 ns.之后对某些疗效不佳且色素较浅层患者改用或交替选择532 nm波长,光斑直径3～4 mm,能量密度1.5～2.0 J/cm2,频率1～5Hz.治疗间隔时间为2～3个月,一般治疗3～4次.结果 治疗4次后治疗组有效率为100％,痊愈率为75.00％,疗效与治疗次数呈正相关.36例(51.43％)患者出现色素沉着,12例(17.14％)出现暂时性色素减退.结论 Q开关Nd: YAG激光1064 nm联合532 nm波长治疗颧部褐青色痣效果满意,虽然术后色素沉着发生率较高,但均能随时间逐渐消退,未见其他不良反应及并发症.     

Non-ablative subsurface remodeling: Clinical and histologic evaluation of a 1320-nm Nd:YAG laser

BACKGROUND: Laser resurfacing in the treatment of facial rhytids has traditionally involved ablative methods with their associated complications and limitations. Rhytid improval requires dermal collagen remodeling. Dermal remodeling can occur without epidermal ablation. OBJECTIVE: The aim of this study was to evaluate the clinical and histologic changes occurring after treatment with a 1320-nm Nd:YAG laser. METHODS: Ten subjects with class I-III rhytids and Fitzpatrick skin types I-II were treated four times with a 1320-nm Nd:YAG laser. Subjects were evaluated for degree of clinical improvement and histologic evidence of new collagen formation six months after their final treatment. RESULTS: Eight subjects showed subjective improvement in the quality of their skin. All ten subjects showed histologic evidence of new upper papillary dermal collagen formation. CONCLUSION: 1320-nm Nd:YAG laser irradiation can lead to new collagen formation and associated clinical improvement. Such improvement can occur without epidermal ablation.     

Tattoo removal by Q-switched Nd:YAG laser: an objective evaluation using histometry

Background: Tattoos have played an important role in various human cultures for thousands of years. The creation of high power, short pulse Q-switched lasers (QS) has provided a tool for considerable therapeutic advances in tattoo removal. Objective: The aim of the study is to correlate the clinical efficacy of QS Nd: YAG laser for tattoo removal with histological as well as histometric findings. Patients and Methods: QS Nd: YAG laser was used for blue tattoo removal in 12 Egyptian patients. Sessions were done every 2 months for about 6–10 sessions (average 7). Skin phototypes of patients ranged from phototype III to V. Photographs were taken before and after every treatment session. Skin biopsies were taken from the patients before treatment and after six sessions to perform histological and histometric analysis. Results: Eight patients (66.7%) showed excellent response and four patients (33.3%) good response. No textural change or scarring was observed in any patient. Histological examination confirmed the clinical response. Haematoxylin and Eosin (H&E) stained sections showed a significant decrease or almost complete disappearance of the tattoo pigment. Meanwhile, histometric study objectively confirmed a significant decrease in ink particle surface area after treatment. Conclusion: QS Nd: YAG laser effectively treats tattoos in dark-skinned Egyptian patients with excellent cosmetic outcome and minimal side effects. The histopathologic and histometric findings significantly correlated with the clinical response.