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1.
Mahmoud Abdallah El-Husseiny Ashraf Abdel-Hameed Abdel-Moneim Mohammed Arafat Abdel-Maksoud Kamel Suliman Hammad 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(4):491-495
Objective
The study was performed to evaluate the technique of laproscopic minigastric bypass for metabolic syndrome patients.Study design
The patients were enrolled in a combined prospective study and had a retrospectively gathered outcome analysis.Patient and methods
The study includes thirty patients; 24 females and 6 males suffering from metabolic syndrome with a mean age of 33.15?±?10.17?years (range, 20–59), who fulfilled the criteria for bariatric surgery with BMI >35 with associated co-morbidities, all patients underwent laparoscopic mini-gastric bypass.Results
BMI and WC were significantly reduced post-operatively; also co-morbidities as DM, hypertension and dyslipidemia were resolved or controlled. The mean operative time was 90?±?12.6?min (range, 80–120). No mortality was reported within 30?days of surgery.Conclusion
Laparoscopic mini gastric bypass is an effective procedure for the treatment of obesity, HTN, type 2 DM and dyslipidemia, technically feasible, safe operation with a low rate of major postoperative complications. 相似文献2.
Garland Castaneda Taft Bhuket Benny Liu Robert J. Wong 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(1):5-8
Aims
Better understanding risk factors for metabolic syndrome (MetS) will allow early targeted intervention to mitigate long term risk. We aim to determine the disparate impact of each individual MetS component on overall risk of developing MetS, stratified by sex, race/ethnicity, and age.Methods
Using data from the 2003–2014 National Health and Nutrition Examination Survey (NHANES), MetS prevalence among adults (age ≥18) was stratified by sex, race/ethnicity, age, and by individual MetS components (e.g. hypertension (HTN), diabetes mellitus (DM), waist circumference, serum high density lipoprotein (HDL), serum triglycerides (TG). Mutlivariate logistic regression models were used to evaluate the disparate impact of each risk factor on MetS risk.Results
Overall MetS prevalence was 33.3%, with the highest prevalence among older individuals, among women, and among Hispanics. When stratified by each individual component of MetS, low serum HDL was the strongest predictor of MetS risk overall and among both men and women, among all race/ethnic groups, and among all age groups (overall: OR 20.1, 95% CI 18.6–21.7). While presence of DM also increased an individual’s risk of MetS, DM was the weakest predictor of MetS.Conclusions
Among U.S. adults, low serum HDL carries the strongest risk in predicting development of MetS. This effect was seen among men and women, among all race/ethnic groups, and among all age groups, highlighting the importance of low serum HDL as a marker of MetS risk. 相似文献3.
Armindo Sousa Ribeiro Rui Seixas Juan Manuel Gálvez Vicente Climent 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):885-891
Aims
The primary objective of our study is to determine the prevalence of the metabolic syndrome in the population. The secondary objective is to determine the prevalence of cardiovascular risk factors, anthropometric alterations and the prevalence of target organ damage and their relationship with aging.Material and Methods
The sample for the study was obtained by means of a consecutive population-based demonstration in 803 adults over 18 years of age belonging to the labor force of the company Grupo Delta SA. The study was carried out according to the guidelines of the Declaration of Helsinki. The individuals included in the study voluntarily participated, once informed of the purpose of the study, giving their prior verbal consent, to the company's human resources department, in the case of Delta Group workers.Results
23.8% of the population has metabolic syndrome more prevalent in males, no smoking, no significant alcohol consumption, sedentary, with a high Body mass index (BMI). Its prevalence increases with age.Conclusion
We found that the prevalence of metabolic syndrome increases with age and is present in people of working age, increasing the risk of cardiovascular diseases, work-related absences, and socio-economic costs. 相似文献4.
Carolyn F. Pedley L. Douglas Case Caroline S. Blackwell Jeffrey A. Katula Mara Z. Vitolins 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(3):215-220
Aims
Large-scale clinical trials and translational studies have demonstrated that weight loss achieved through diet and physical activity reduced the development of diabetes in overweight individuals with prediabetes. These interventions also reduced the occurrence of metabolic syndrome and risk factors linked to other chronic conditions including obesity-driven cancers and cardiovascular disease. The Healthy Living Partnerships to Prevent Diabetes (HELP PD) was a clinical trial in which participants were randomized to receive a community-based lifestyle intervention translated from the Diabetes Prevention Program (DPP) or an enhanced usual care condition. The objective of this study is to compare the 12 and 24 month prevalence of metabolic syndrome in the two treatment arms of HELP PD.Materials and methods
The intervention involved a group-based, behavioral weight-loss program led by community health workers monitored by personnel from a local diabetes education program. The enhanced usual care condition included dietary counseling and written materials.Results
HELP PD included 301 overweight or obese participants (BMI 25–39.9 kg/m2) with elevated fasting glucose levels (95–125 mg/dl). At 12 and 24 months of follow-up there were significant improvements in individual components of the metabolic syndrome: fasting blood glucose, waist circumference, HDL, triglycerides and blood pressure and the occurrence of the metabolic syndrome in the intervention group compared to the usual care group.Conclusions
This study demonstrates that a community diabetes prevention program in participants with prediabetes results in metabolic benefits and a reduction in the occurrence of the metabolic syndrome in the intervention group compared to the enhanced usual care group. 相似文献5.
Nuha Alwardat Laura Di Renzo Renata Costa de Miranda Sofian Alwardat Paola Sinibaldi Salimei Antonino De Lorenzo 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(5):661-666
Background
Hypertension (HTN), dyslipidemia and hyperglycemia are major risk factors for cardiovascular disease, accounting for the highest morbidity and mortality among the elderly Jordanian population. This study aimed to evaluate serum lipid and glucose profiles of hypertensive patients and normotensive controls, and determine the risk factors for HTN among elderly population in Jordan.Methods
A cross-sectional study was carried out among 200 participants, including 111 hypertensive patients and 89 normotensive controls from June to October 2017 in North Jordan. Data were collected on sociodemographic factors, anthropometric measurements, blood pressure, and lipid profile including total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) and fasting blood sugar (FBS).Results
Serum levels of TC, TG, LDL and FBS were higher while HDL levels were lower in hypertensive subjects compared to normotensives (p?<?0.01). There were no differences between hypertensive and normotensives patients regarding their age, waist circumference (WC), waist-to-height ratio (WHtR) and body mass index (BMI). Anthropometric and biochemical parameters were significantly correlated only in normotensive group. Significant associations between blood pressure and biochemical parameters were seen only in the HTN group. Overweight/obesity, abdominal obesity (WHtR), hyperglycemia, hypertriglyceridemia and low HDL were found as the risk factors for HTN.Conclusion
from our results, future strategies for preventing dyslipidemia, hyperglycemia and, consequently, HTN through modification of risk factors such as lifestyle changes and medical management. It's recommended for patients with HTN to measure the BP, lipid and glucose profiles regularly throughout their primary health care to prevent non-communicable diseases. 相似文献6.
Sandra Maria Barbalho Ricardo José Tofano André Luis de Campos Aniele Sanches Rodrigues Karina Quesada Marcelo Dib Bechara Ricardo de Alvares Goulart Marie Oshiiwa 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(4):501-507
Background
The concern with the incidence of chronic-degenerative diseases is increasing worldwide, and many studies have shown that insufficiency of vitamin D (VD) can be linked to several metabolic disorders.Aims
Thus, the objective of this study was to evaluate the association of the metabolic syndrome risk factors, atherogenic indices and VD in a group of patients attended at a Cardiology Center.Methods
For this study, we invited 200 patients of both sexes attended in a Cardiology Center (Medical School of Marilia – São Paulo – Brazil). Most were female (n?=?111) and aged between 41 and 70 years (from march to august, 2017).Results
Our results showed that only 20.0% of the patients presented normal levels of VD. Patients with altered values for this vitamin presented significantly higher values for glycemia, HbA1c, Total cholesterol, LDL-c, triglycerides, Castelli Index I, Castelli Index II, Body Mass Index, waist circumference, non-HDL-c and the estimative of the size of the LDL-c particle. Vitamin D correlated negatively with glycemia, HbA1C, triglycerides, atherogenic indices, Body Mass Index, and blood pressure. Multiple Regression Model showed that for an individual to maintain metabolic parameters, at least at borderline values, the levels of VD should be 37.64 that is not in accordance with the reference values.Conclusions
These results showed a remarkable prevalence of low concentrations of Vitamin D in patients with cardiovascular risk factors. 相似文献7.
Tarek Mohamed Ali Ahmad El Askary 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):1045-1050
Background
Inconsistent results have been described regarding the part of fetuin-A and testosterone in arterial stiffness in type 2 diabetes mellitus (T2DM).Aim
To look into the links of serum fetuin-A and testosterone levels with brachial-Ankle pulse wave velocity (baPWV), a marker of arteriosclerosis and common carotid intima media thickness (ccIMT), a marker of early atherosclerosis, in diabetic Saudi men patients.Subjects and methods
One hundred and fifty adult male patients with T2DM and 60 non-diabetic control subjects were enrolled from different Saudi Arabia Taif hospitals. Biochemical analysis, anthropometric measurements, blood pressure, baPWV and ccIMT were investigated.Results
Stepwise regression in diabetic patients revealed that the most important predictor of ba-PWV was serum fetuin-A followed by serum glucose and the most important predictor of ccIMT was serum fetuin-A followed by serum HDL then serum triglycerides.Conclusions
Only fetuin-A levels not testosterone are negatively associated with early markers of atherosclerosis. 相似文献8.
Sharmin Mahbuba Fauzia Mohsin Farhana Rahat Jebun Nahar Tahmina Begum Nazmun Nahar 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(3):369-374
Aims
The study was done to assess the magnitude of problems of metabolic syndrome among obese adolescents.Materials and method
It was a cross-sectional study done from January 2013 to June 2014 in paediatric endocrine outpatient department in BIRDEM General Hospital, Dhaka, Bangladesh. Total 172 adolescents having exogenous obesity aged 10–18 years were included. Impaired fasting glucose (IFG), impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM) were defined as per WHO criteria.The adolescents having Body Mass Index (BMI) ≥95th centile were classified as obese.Waist circumference was measured at the level midway between the lower rib margin & the iliac crest, at the level of umbilicus with the person breathing out gently in centimeter. Hip circumference was measured at the maximum width over the buttocks at the level of the greater trochanters in centimeter.Result
Among 172 obese adolescents, metabolic syndrome was found in 66 patients (38.4%). The commonest metabolic abnormality among those having metabolic syndrome was low HDL level (77.3%) followed by high triglyceride level(71.2%). Glucose intolerance (IFG and/or IGT) was found in 16.7%, Type 2 DM in 10.6%, systolic hypertension in 10.7% and diastolic hypertension in 12.1%. Triglyceride (p?=?0.042) and Cholesterol level (p?=?0.016) were significantly higher and HDL-cholesterol level (p?=?0.000) was significantly lower among obese adolescents having metabolic syndrome. Less physical activity (p?=?0.04) was significantly related to the development of metabolic syndrome. On logistic regression analysis male sex, family history of obesity and low HDL-cholesterol correlated to metabolic syndrome.Conclusion
The High rate of metabolic syndrome among obese adolescents is alarming. 相似文献9.
Mansour Agahi Negar Akasheh Afshin Ahmadvand Hossein Akbari Fatemeh Izadpanah 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(1):9-15
Introduction
The use of second-generation atypical antipsychotics has an increasing role in the development of metabolic syndrome. However, these medications due to metabolic disorders can lead to an increased risk of cardiovascular disease and subsequently mortality as well as reduced adherence to treatment. The main objective of current study was to determine the ability of melatonin to reduce the metabolic effects of second-generation antipsychotics.Methods
This double blind controlled clinical trial was conducted on 100 patients aged 18–64 years old were treated with the second-generation antipsychotics for the first time. The patients were divided randomly into two groups of 50. The case group received slow-release melatonin at a dose of 3 mg and the control group was given oral placebo at 8 p.m.Results
The findings in melatonin group indicated significantly increase of HDL and decreased fasting blood sugar and systolic blood pressure, as well as had statistically significant increase in waist circumference, weight and BMI compared with placebo group.Conclusion
According to the findings, it can be claimed that the addition of melatonin to atypical antipsychotics has led to a reduction in some of the metabolic effects of these drugs. In this study, HDL level was increased, and the mean systolic blood pressure and FBS were decreased in the melatonin group. Considering that these factors are contributing to cardiovascular disease as a leading cause of mortality in psychiatric patients, so the use of melatonin can reduce some of the medical effects of long-term treatment of atypical antipsychotics. 相似文献10.
Obesity and cardio-metabolic risk factors in Ecuadorian university students. First report, 2014–2015
Cesar Ruano Erika Lucumi José Albán Sofía Arteaga Martha Fors 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):917-921
Objective
Overweight and obesity are risk factors for developing cardiovascular disease. The objective of this study was to determine the prevalence of obesity and risk factors associated with metabolic syndrome and cardiovascular disease in university students.Methods
883 students from the Faculty of Medical Sciences of the Central University of Ecuador were included, who were surveyed with demographic data, smoking habits and physical activity. Body mass index, abdominal circumference and blood pressure were determined. Blood chemistry and lipid profile were performed. Central tendency and dispersion measures, average comparisons (Student's T) and Pearson's correlation were calculated to study quantitative variables and χ2 distributed statistic for the comparison of qualitative variables.Results
The prevalence of overweight and obesity was 25.5%. The body mass index was similar in both sexes (23.15 women / 23.57 men), waist circumference was higher in women. Men had higher than normal levels in blood pressure and elevated triglycerides while women had high cholesterol.Conclusions
One of four students presents some degree of overweight or obesity and an important percentage of altered levels of plasma lipids and blood pressure. Blood glucose levels were found in normal ranges. 相似文献11.
Kijung Yoon Seungho Ryu Jieun Lee Jung-Duck Park 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):977-983
Aims
To determine whether hs-CRP level and interval change of hs-CRP could predict the development of metabolic abnormalities in healthy subjects in a longitudinal study.Methods
A cohort of 3748 male who had normal hs-CRP level without evidence of any component of metabolic syndrome were studied. At each visit, hs-CRP level and metabolic abnormalities were measured. Interval change of hs-CRP for each subject was calculated. COX proportional hazard model and logistic regression analysis were used.Results
Cumulative incidence and incidence density of metabolic syndrome were 3.96% and 7.17 per 1000 person-year, respectively. Cumulative incidence of metabolic syndrome was significantly increased according to hs-CRP tertile level. This significance remained after adjusting age, smoking, drinking, and exercise. Although the hazard ratio of metabolic syndrome for incidence density was increased significantly as hs-CRP increased, such trend disappeared after adjusting for confounding variables. The risk of metabolic syndrome was significantly higher (1.48 times) in the hs-CRP increased group than that in the decreased or unchanged group. This significance remained after controlling for covariates.Conclusion
Relatively higher hs-CRP level within normal range may predict the increase of metabolic syndrome compared to lower hs-CRP. Increased hs-CRP level may increase the incidence of metabolic syndrome. 相似文献12.
Kamna Singh Ritu Singh Sudhir Chandra Sanjay Tyagi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(3):275-278
Objectives
The present study aims to evaluate the levels of HDL and Paraoxonase-1 (PON1) and their correlation in atherosclerotic patients with and without diabetic mellitus (DM) as well as in control subjects in Northern Indian population.Materials and methods
We analyzed lipid profiles and Serum PON1 levels by automated analyzer and ELISA, respectively. Study subjects (N?=?150) were divided in three groups; Group I: Atherosclerotic patients without DM (N?=?50), Group II: Atherosclerotic patients with DM (N?=?50); Group III: Controls (N?=?50).Results
We found a significantly (p?<?0.0001) low levels of HDL-C in Group I (32.2?±?7.3) and Group II (36.9?±?11.5) as compared to Group III (41.0?±?7.1). PON-1 levels were also significantly lower in Group I (60.1?±?10.5) and Group II (50.0?±?13.9) when compared to Group III (95.0?±?12.0). We observed a significant correlation (r?=?0.59, p?<?0.001) between the levels of PON1 and HDL-C in study subjects.Conclusions
The reduced levels of HDL and PON-1 and their significant correlation in CAD patients may be associated with the pathogenesis of this disease. Considering HDL as a dependent variable, Paraoxonase-1 is the most important parameter contributing to the total variation in HDL in CAD. 相似文献13.
14.
Basma Damiri Amir Aghbar Saja Alkhdour Yousef Arafat 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(3):343-348
Objectives
Metabolic Syndrome “MetS” is characterized by the presence of several factors that play a major role in the development of cardiovascular diseases and diabetes mellitus. This study was conducted to establish the prevalence of MetS and its individual components among the overweight and obese students at An-Najah National University (ANU) using IDF and modified NCEP ATP III definition and to identify conditions associated with it.Materials and methods
A cross-sectional study was conducted in 2016. Data were collected in two stages: first stage included anthropometric and blood pressure measurements for 850 participants. Second stage included a self-administered questionnaire and biochemical analysis for only overweight or obese (154) participants.Results
The prevalence of overweight and obesity was 26.2%, with significant increase among males (36.4%) compared with females (19.1%). The prevalence of MetS among obese and overweight was (28.6%) according to IDF with no significant increase compared to NCEP ATP criteria (24%). Reduced HDL- cholesterol was the most prevalent component (74.7%) in obese and overweight participants followed by central obesity (72.1%), raised blood pressure (29.9%), elevated fasting blood sugar (24%), and lastly increased triglycerides (18.2%). No significant differences were found between males and females according to both criteria. Moreover, no significant associations with geographic locality, house-hold income, smoking, physical activity, or family history were determined.Conclusions
The prevalence of MetS among overweight and obese young adult Palestinians was high and demands immediate intervention, given the potential for these adults to develop chronic diseases. 相似文献15.
Jamal Ahmadzadeh Behnam Mansorian Mohammad Mirza-Aghazadeh Attari Ira Mohebbi Raha Naz-Avar Karaim Moghadam Seyyed Adel Khoshbou Ghareh-bagh 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(1):17-21
Aims
Some studies have demonstrated that metabolic syndrome is associated with hematological parameters. The present study explores the relationship between hematological parameters and numbers of metabolic syndrome conditions in Iranian men.Methods
This cross-sectional study included 11,114 participants who were professional drivers of commercial motor vehicles, and were enrolled in the Iranian Health Surveys between 2014 and 2016. Diagnosis of metabolic syndrome was made according to International Diabetes Federation criteria. Clinical data, including anthropometric measurements and serum parameters, were collected. Odds ratios for hematological parameters and metabolic syndrome were calculated using binary logistic regression models.Results
We found that hemoglobin; platelet, and white blood cell counts increased with increasing numbers of metabolic syndrome components (p < 0.05 for all). The odds ratio of metabolic syndrome significantly increased across successive quartiles of platelet (1.00, 1.25, 1.29, and 1.51) and white blood cell counts (1.00, 1.51, 1.79, and 2.11) with the lowest quartile as the referent group. Similar associations for hemoglobin and hematocrit in the top quartile were also observed. We did not observe any significant difference in the mean of neutrophil count, mean platelet volume (MPV), red cell distribution width, or platelet distribution width among participants with or without metabolic syndrome.Conclusions
Our findings indicate that high levels of major hematological parameters such as hemoglobin, hematocrit, as well as platelet and white blood cell counts could be novel indicators for the development of metabolic syndrome. 相似文献16.
Ezatollah Fazeli Moghadam Artashes Tadevosyan Ebrahim Fallahi Reza Goodarzi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2017,11(1):7-11
Introduction
Dietary factors can affect the coronary heart disease (CHD). Results of previous studies on the association between the diet and CHD are not consistent in different countries. There were no data on this association in Armenia.Objective
Aims of this case-control study were to evaluate the association between nutritional factors and CHD among Armenians in Yerevan.Methods
During 2010 and 2011, we randomly selected 320 CHD patients with a diagnosis of CHD less than 6 months and 320 subjects without CHD (≥30 years old) from the hospitals and polyclinics in Yerevan. Dietary intakes with 135 food items over the previous 12 months were evaluated using a semi-quantitative food frequency questionnaire.Results
After adjusting for some CHD risk factors higher intakes of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) were associated with a reduced risk of CHD, while this association was not witnessed for saturated fatty acids (SFA). In addition, findings indicated an inverse relation between vitamins (E, B6 and B12, folic acid) and fiber with CHD. In this population, smoking, hypertension, and metabolic syndrome (MetS) were significantly more common among patients with CHD.Conclusion
The intake of vitamins E, B6 and B12, folic acid, PUFA, MUFA and fiber appeared to be predictors of CHD, independently of other risk factors. 相似文献17.
Marie Doualla-Bija Yonathan Lobe Batchama Jude Moutchia-Suh Vicky Joceline Ama Moor Félicité Kamdem Fernando Kemta Lekpa Henry Luma Namme 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(6):1007-1011
Background
Evidence from epidemiological studies suggests an important association between gout and the metabolic syndrome (MetS). However, to the best of our knowledge, prevalence of metabolic syndrome in gout has not been reported in sub-Saharan African (SSA) settings.Objectives
The aim of this study was to determine the prevalence and characteristics of MetS in gout in a SSA population.Method
After prior ethical clearance, we carried out a cross-sectional study involving gout patients in a referral hospital in Douala-Cameroon. Metabolic syndrome was defined using International Diabetes Foundation criteria. Associations between variables were assessed using logistic regression.p?<? 0.05 was considered significant.Results
On 174 gout patients (48.3% females) who consented to participate in the study, the median (IQR) age was 55.00 (14.25) years, and the median (IQR) duration of gout was 7.5 (10.0) years. Prevalence of metabolic syndrome was 54.6% (95% CI: 47.9%–62.8%). One hundred and forty-seven (84.5%) participants had central obesity, 62 (35.6%) raised triglycerides, 79 (45.4%) reduced HDL-C, 129 (74.1%) raised blood pressure, and 85 (48.9%) had raised fasting plasma glucose. On logistic regression analyses, gout patients with metabolic syndrome significantly had a higher body mass index (OR: 1.09, 95% CI: 1.02–1.17), and higher levels of serum uric acid (OR: 1.02, 95% CI: 1.01–1.04).Conclusions
About 1 out of every 2 gout patients in this population have metabolic syndrome. These gout patients with metabolic syndrome significantly have a higher body mass index, and higher levels of serum uric acid. Cohort studies are required to clearly establish the direction of the relationship between gout and metabolic syndrome. 相似文献18.
Meryem ABI-AYAD Amine Abbou Fatima zahra Abi-Ayad Omar Behadada Mohamed Benyoucef 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(2):175-179
Aim
Hypercholesterolemia and hyper LDL-C are associated with the atherosclerosis (AS). The current study was performed to evaluate the implication of the others lipoproteins (HDL, LDL, VLDL) and apolipoproteins (ApoA1, ApoB100) with subclinical atherosclerosis (carotid plaque) in patients with metabolic syndrome (MetS) free from cardiovascular disease (CVD).Methods
Prospective transversal study was conducted in patients with MetS free from cardiovascular disease (CVD). The lipids, lipoproteins and apolipoproteins were measured. The lipoproteins (HDL, LDL, VLDL) were obtained by the precipitation method. The carotid plaque (CP) was evaluated by ultrasonography, method for assessing AS. Logistic regression and analysis tree were used to look for the association and the incrimination of the lipoproteins with the presence of CP.Results
The CP incidence was 60% among the participants, 34.29% on the right and the left plaque against 25.71% for only one plaque. The HDL-C was the only lipoprotein associated with the CP after adjustment of the age, the sex and BMI (OR: 0.007?P: 0.046) with the logistic regression analysis, HDL-C (<0.35?g/l), ApoA1 (<1.43?g/l) and VLDL-TG (>0.656?g/l) are implicated in the presence of CP with the analysis tree analysis.Conclusion
Lower level of HDL-C is associated with CP, HDL-C, ApoA1, and high level VLDL-TG but not total cholesterol, and LDL-Care useful parameters in the assessment of initial atherosclerosis in metabolic syndrome. 相似文献19.
Ali Abdulmajid Dyab Allawi 《Diabetes & Metabolic Syndrome: Clinical Research & Reviews》2018,12(2):91-97
Background
Inflammation and malnutrition play an important role in endothelial dysfunction, atherosclerosis and excessive cardiovascular morbidity and mortality in ESRD patientsAim of the study
The primary objective is to determine the prevalence of inflammation, malnutrition and atherosclerosis in patients on maintenance haemodialysis. Secondary objective was to determine the association for atherosclerosis with inflammation and malnutrition.Patient and methods
One hundred and one adult patients with end stage renal disease on maintenance haemodialysis who are met with the exclusion criteria were enrolled in this cross sectional study from haemodialysis unit of Baghdad teaching hospital over the period of July/2015 ? June 2016. All patients were thoroughly examined and many variables were evaluated (age, gender, blood pressure, diabetes mellitus, serum lipid profile, smoking habits, serum albumin, CRP, calcium, Phosphate, Parathyroid hormone and haemoglobin measurements). All patients underwent a carotid Doppler ultrasound study.Results
Atherosclerosis was present in 65.3%: 58.4% of patients had malnutrition and 43.6% had inflammation. The association for atherosclerosis and high CRP and low serum albumin is strong and independent of other atherosclerosis risk factors. There is significant inverse and independent correlation between CRP and albumin.Conclusion
Inflammation (high serum CRP) and malnutrition (low serum albumin) in patients on haemodialysis are significantly associated with carotid atherosclerosis. Inflammation was more prevalent in the malnourished patients than in those with normal nutritional status. 相似文献20.
Irene Fuertes de Vega Carola Baliu-Piqué Jordi Bosch Mestres Andrea Vergara Gómez Xavier Vallés Mercè Alsina Gibert 《Enfermedades infecciosas y microbiología clínica》2018,36(3):165-168