保留脾脏的胰体尾切除术九例报告

目的总结9例保留脾脏胰体尾切除术经验,探讨其可行性。方法1991年1月至2004年12月行保留脾脏的胰体尾切除术9例,其中保留脾脏血管的保留脾脏胰体尾切除7例,切断(或切除)脾脏血管的保留脾脏胰体尾切除术2例。结果本组无手术死亡,术后2例发生胰瘘,经非手术治疗2～3周痊愈。结论胰体尾部良性病变,不适合摘除术时应首先选择保留脾脏的胰体尾切除术,手术安全,近期效果好。     

保留脾脏的胰体尾部良性肿瘤切除

目的探讨保留脾脏胰体尾切除的可行性和安全性以及并发症预防。方法回顾性分析总结2009年1月至2011年12月行保留脾脏胰体尾切除术5例资料,其中保留脾脏血管的开腹保脾胰体尾切除3例,切断(或切除)脾脏血管的保脾胰体尾切除术1例,腔镜下保脾胰体尾部切除术1例。结果本组无手术死亡,术后均未发生胰瘘、脾梗死、脾脓肿及脾出血等。随访3～6月,无并发症发生。结论胰体尾部良性肿瘤,应首选保留脾脏的胰体尾切除方法,手术安全,效果好,且避免了脾脏的不必要切除。     

保留脾脏的胰体尾切除术22例报告

目的 总结保留脾脏的胰体尾切除术经验,探讨其可行性与安全性。 方法 回顾性分析中国医科大学附属第一医院1993年4月至2009年7月行保留脾脏的胰体尾切除术22例病人的临床资料。结果 22例病人中,无功能胰岛细胞瘤8例、囊腺瘤8例、胰岛素瘤5例、胰腺假性囊肿1例,均成功完成保留脾脏的胰体尾切除术,其中保留脾脏血管18例,切断脾脏血管4例。无围手术期死亡。术后发生胰瘘5例,经非手术治疗2～3周痊愈。结论 对于胰体尾部良性病变者,不适合行摘除术时应首先选择保留脾脏的胰体尾切除术,安全可行。     

保留脾脏和脾脏血管的胰体尾切除术

目的 探讨胰腺体尾部病变行保留脾脏和脾脏血管的胰体尾切除术的可行性与适应证.方法 对我院200r7年3月至6月间收治的3例胰腺体尾部病变患者.施行保留脾脏与脾脏血管的胰腺体尾部切除术.术中仔细解剖胰腺体尾部,显露牌动静脉,不离断脾动静脉和胃短血管,不游离脾脏.术后在胰腺断面常规放置引流管.结果 3例患者均成功完成保留脾脏和脾脏血管的胰体尾切除术,术中均未输血.术后并发胰瘘1例、并发创伤性胰腺炎1例,均经非手术治疗痊愈.结论 保留脾脏和脾脏血管的胰腺体尾部切除术是安全可行的,对于胰腺体尾部良性病变、尤其是儿童患者,本手术应作为首选的术式.     

腹腔镜保留脾脏胰体尾切除术治疗胰腺囊性疾病6例报告

目的总结腹腔镜保留脾脏胰体尾切除术的临床经验与手术技巧。方法自2003年11月至2006年7月，我们对6例胰腺囊性疾病患者施行保留脾血管的腹腔镜保留脾脏胰体尾切除术。结果本组6例均在腹腔镜下完成，其中1例合并右肾上腺肿瘤切除，1例合并子宫肌瘤切除、左卵巢畸胎瘤切除，1例合并子宫肌瘤切除，1例合并胆囊切除。手术时间140～265min，出血350～600ml。术后住院时间4—9d，无胰漏发生。随访1—31个月，症状消失，未见复发。病理诊断：潴留性囊肿2例，浆液性囊腺瘤2例，黏液性囊腺瘤2例。结论对于胰体尾部良性病变，应首选保留脾血管的腹腔镜保留脾脏胰体尾切除术，施行保留脾血管的腹腔镜保留脾脏胰体尾切除术是安全可行的。     

脾血管优先技术在腹腔镜保留脾脏胰体尾切除术中的应用

[摘 要] 目的 探讨脾血管优先技术在腹腔镜保留脾脏胰体尾切除术中的应用。方法 回顾性分析2011年6月至2017年12月浙江省人民医院和浙江省长兴县人民医院采用腹腔镜保留脾脏胰体尾切除术治疗的58例胰体尾良性或交界性占位病变患者的临床资料。结果 中转开腹2例;余56例均顺利完成手术,其中保留脾动、静脉的保脾胰体尾切除术（Kimura法）53例,离断脾血管、保留胃短血管的保脾胰体尾切除术（Warshaw法）3例。手术时间65～220（160±30）min,出血量30～500（100±25）mL,术后住院时间5～21（8±5）d。术后并发生化瘘15例,B级胰瘘2例,C级胰瘘1例,腹腔出血1例,腹腔脓肿2例,肺部感染2例。术后病理诊断为胰腺内分泌肿瘤8例,胰腺导管内乳头状黏液瘤10例,胰腺实性假乳头状瘤12例,黏液性囊腺瘤10例,浆液性囊腺瘤13例,慢性胰腺炎肿块5例。结论 脾血管优先技术具有简便、安全的特点,有助于主动选择术式和规划手术路径,提高腹腔镜胰尾切除术的安全性和保脾成功率。     

腹腔镜保留脾脏胰体尾切除术的关键技术

腹腔镜保留脾脏胰体尾切除术适用于胰体尾部良性或低度恶性病变,避免了脾切除术后近、远期并发症,手术方式包括保留脾动静脉的Kimura手术和切除脾动静脉主干、保留胃网膜左血管等侧枝循环的Warshaw手术。腹腔镜下Kimura手术视野清晰,安全可行,术后并发症发生率低,应为保脾胰体尾切除手术的首选。术前检查或术中探查可疑为浸润性恶性病变或病灶与脾血管、脾门关系密切者,应果断放弃保脾术式,改行胰体尾联合脾切除术。     

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胰腺体尾部与脾血管及脾脏关系密切，传统的胰体尾切除术，理所当然的切除脾脏。故有人将其认为是一个解剖单位。正常的脾脏被切除，称为“无辜性脾切除”。当脾脏抗感染及抗癌肿的功能被确认后，国际上从20世纪70年代，我国自80年代起，各种保留脾脏的手术兴起，其中胰体尾部良性病变需要行胰体尾切除时，如何保留脾脏令人关注。基于对脾脏血管的研究，     

保留脾脏的胰体尾切除术研究进展

近年来,保留脾脏的胰体尾切除术倍受人们的关注.本文就胰体尾切除术中脾脏是保留还是切除、切除脾动静脉的保留脾脏胰体尾切除术是否安全、胰体尾部恶性肿瘤是否适宜保脾及腹腔镜保留脾脏的胰体尾切除术等方面的研究进展进行综述.     

腹腔镜胰腺远端切除术26例

目的探讨腹腔镜胰腺远端切除术的安全性、可行性。方法2005年9月～2008年6月,对26例胰腺体尾部肿物行腹腔镜胰腺远端切除术。术前25例诊断为胰腺体尾部良性肿物,1例不除外恶性,肿物中位直径5cm（1.2～10cm）。结果所有手术均在全腹腔镜下完成。15例行保留脾脏的胰体尾切除（10例保留脾动静脉,5例未保留脾动静脉）,10例行胰体尾加脾切除,1例既往行胰体尾及脾切除者行胰体部切除。手术中位时间268.5min（129～400min）,中位出血量100ml（50～800ml）,术后中位住院时间9d（6～21d）。无胰漏或脾梗死发生,2例包裹性积液,均保守治疗治愈,1例引流管口感染。26例中位随访时间15.5月（1～35个月）,均无复发。结论胰腺体尾部良性肿物行腹腔镜胰腺远端切除术安全、可行。     

Laparoscopic spleen-preserving distal pancreatectomy

Distal pancreatectomy with spleen preservation may be the preferred procedure for certain benign tumors and cystic lesions of the pancreatic body or tail. Alternatively, laparoscopic removal including either distal pancreatectomy with splenectomy or splenic-preservation with ligation of the splenic vessels have also been described. We describe, herein, our method to perform spleen-preserving laparoscopic distal pancreatectomy that preserves the splenic vessels and hence splenic function. The described technique of spleen-preserving distal pancreatectomy has been used in two patients with favorable results. Both patients underwent laparoscopic distal pancreatectomy with splenic conservation for an oligocystic serous cystadenoma and serous cystadenoma. Operative time was 3–6 hours with total blood loss of less than 200 cc in both cases. The length of stay in the hospital was 4–8 days and both patients returned to work within 3 weeks. Laparoscopic spleen-preserving distal pancreatectomy should be considered for younger patientswith select body or tail lesions that are not candidates for less extensive procedures.     

Pankreaslinksresektion

During recent years, spleen-preserving distal pancreatectomy (SPDP) has broadened the operative spectrum in pancreatic surgery. The rationale for spleen-preserving procedures comprises prevention of overwhelming postsplenectomy infection syndrome (OPSI) and possibly an advantage regarding reduced carcinogenesis. Although there are no prospective randomized trials, SPDP and distal pancreatectomy with splenectomy (DPSx) seem to be equivalent in terms of blood loss, operative time, mortality and frequency of reoperation. Concerning pancreatic fistulas and other major surgical complications, current data from the literature are conflicting. Long-term effects of SPDP, such as development of gastric varices due to portal hypertension, are still insufficiently investigated. However, SPDP should always be considered in patients with benign tumors of the pancreatic tail and chronic pancreatitis. Spleen-preserving distal pancreatectomy can also be combined with resection of the splenic vessels (DPSx-SVx) if the blood supply of the spleen via the small gastric vessels and the gastro-epoploic arcade is sufficient. In the presence of malignant tumors, DPSx is necessary for oncological reasons.     

腹腔镜下保留脾脏的胰体尾切除术的临床研究

目的:探讨腹腔镜下保留脾脏的胰体尾切除术的临床价值。方法:回顾分析2014年11月至2016年4月为3例胰腺体尾部肿瘤患者行腹腔镜下保留脾脏的胰体尾切除术的临床资料。结果:3例均成功施行腹腔镜下保留脾血管的保脾手术,无中转开腹,其中1例术中撕裂脾静脉,腹腔镜下缝合脾静脉撕裂处,成功止血,72 h后恢复进食。1例患者因囊性肿瘤巨大,术中囊液外溢,造成术后胰腺切除区形成直径3 cm包裹性积液,术后2周自行吸收。术后病理均回报为胰腺粘液性囊腺瘤。出院后随访3～12个月,未见远期并发症及复发病例。结论:腹腔镜下保留脾脏的胰体尾切除术目前已成为治疗胰体尾良性肿瘤安全、可行的新选择,因其创伤小、康复快,已成为治疗胰体尾良性肿瘤的常规手术,目前也可在基层医院开展,但此术式仍需严格遵守循序渐进的推行原则。     

Revisiting vascular patency after spleen-preserving laparoscopic distal pancreatectomy with conservation of splenic vessels

Background

We evaluated vascular patency and potential changes in preserved spleens after laparoscopic spleen-preserving distal pancreatectomy (SPDP) with conservation of both splenic vessels.

Methods

We retrospectively analyzed the patency of conserved splenic vessels in patients who underwent laparoscopic or robotic splenic vessel-conserving SPDP from January 2006 to August 2010. The patency of the conserved splenic vessels was evaluated by abdominal computed tomography and classified into three grades according to the degree of severity.

Results

Among 30 patients with splenic vessel-conserving laparoscopic SPDP, 29 patients with complete follow-up data were included in this study. During the follow-up period (median: 13.2?months), grades 1 and 2 splenic arterial obliteration were observed in one patient each. A total of five patients (17.2%) showed grade 1 or 2 obliteration in conserved splenic veins. Most patients (82.8%) had patent conserved splenic vein. Four patients (13.8%) eventually developed collateral venous vessels around gastric fundus and reserved spleen, but no spleen infarction was found, and none presented clinical relevant symptoms, such as variceal bleeding. There was no statistical difference in vascular patency between the laparoscopic and robotic groups (P?>?0.05).

Conclusions

Most patients showed intact vascular patency in conserved splenic vessels and no secondary changes in the preserved spleen after laparoscopic splenic vessel-conserving SPDP.     

保留脾脏的胰体尾切除术28例报告

目的探讨保留脾脏的胰体尾切除术(SPDP)的可行性和手术技巧,比较SPDP与胰体尾、脾切除术(DP)患者的临床疗效。方法回顾性分析胰体尾切除术患者临床资料58例,其中DP30例(A组),SPDP28例(B组),B组又分为B1(保留脾血管组)和B2(合并脾血管切除组)两个亚组。比较两组在手术时间、术中出血量、术后并发症发生率及术后Α院时间的差异。结果 A、B组的手术时间、术中出血量、术后并发症发生率、胰瘘发生率、肺部感染发生率的组间差异均无统计学意义;SPDP组术后Α院时间明显较DP组短(P0.05)。B1亚组较B2亚组手术时间明显延长(P0.05);术中出血量、术后总的并发症发生率、胰瘘发生率、肺部感染发生率、术后Α院时间的差异无统计学意义。B1组与B2组的术后并发症发生率及术后Α院时间的差异无统计学意义。结论保留脾脏的胰体尾切除术不增加并发症发生率,而术后Α院时间缩短。保留脾血管㈦否对术后并发症发生率及术后Α院时间无影响。     

Evaluation of splenic circulation after spleen-preserving distal pancreatectomy by dividing the splenic artery and vein

BACKGROUND/AIM: In the present study, we investigated the acute and late phases of splenic circulation after spleen-preserving distal pancreatectomy (SPDP) involving the division of splenic vessels. METHODS: An acute phase of splenic circulation was evaluated by laser flow meter and the late phase was estimated by (99m)Tc-galactosyl human serum albumin spleen scintigraphy. RESULTS: Splenic blood supply, evaluated by laser flow meter immediately after SPDP, dropped to one half of the prior blood supply. However, blood supply recovered 10 days after SPDP, as estimated by (99m)Tc-galactosyl human serum albumin spleen scintigraphy. CONCLUSION: There are two variations of SPDP: SPDP without preservation of the splenic artery and vein, and SPDP with preservation of the splenic artery and vein. The disadvantage of the former is the resulting decrease in splenic blood supply. The present findings may help to make up for this disadvantage.     

Open and Laparoscopic Spleen-preserving,Splenic Vessel-preserving Distal Pancreatectomy: Indications and Outcomes

Background  Spleen-preserving distal pancreatectomy has been described lately in order to reduce the risks associated with splenectomy. The aim of this study is to report a series of open and laparoscopic distal pancreatectomies with splenic vessel preservation. Methods  From June 2001 to April 2007, 11 spleen-preserving distal pancreatectomies were performed, utilizing open and laparoscopic techniques. The main variables recorded were demographics, intra- and postoperative complications, and final pathology results. Results  All 11 spleen-preserving distal pancreatectomies were performed successfully. Laparoscopic resection was possible in seven patients. Postoperative morbidity consisted of one pancreatic fluid collection. The overall incidence of pancreatic leak was 18%. The final pathology revealed serous cystadenoma in 36% of the cases, neuroendocrine tumor in two cases, three mucinous cystadenomas, one carcinoid tumor, and one intrapancreatic spleen. With a median follow-up of 26 months, no splenic vein thrombosis was detected. Conclusions  Open or laparoscopic spleen-preserving distal pancreatectomy with splenic vessel preservation is a feasible and safe procedure. In selected cases of cystic lesions and low grade neoplasms, distal pancreatectomy with splenic preservation is possible. Presented at: 2007 American Hepato-Pancreato-Biliary Association. April 19–22, 2007, Las Vegas, NV, USA.     

Laparoscopic spleen-preserving distal pancreatectomy for solid pseudopapillary tumor with conservation of splenic vessels in a child

Laparoscopic spleen-preserving distal pancreatectomy (LSDP) with conservation of the splenic vessels is gaining acceptance as a reliable treatment for selected patients with low-grade malignant tumors of the pancreas in adults. The operation requires advanced laparoscopic skills to safely divide the fine branches of the splenic vessels. Laparoscopic spleen-preserving distal pancreatectomy with conservation of splenic vessels is rarely reported in children. We describe a 12-year-old girl with solid pseudopapillary tumor in the body of the pancreas that was successfully treated with LSDP, preserving the splenic vessels. The postoperative course was uneventful, and the functional and aesthetic results were satisfactory. Laparoscopic spleen-preserving distal pancreatectomy with conservation of splenic vessels may be a safe and feasible treatment option for children with pancreatic disease.