Q开关Nd:YAG激光治疗色素增加性皮肤病128例临床疗效分析

目的：观察Q开关Nd：YAG激光治疗色素增加性皮肤病临床疗效与美容效果以及治疗次数。方法：Q开关Nd：YAG激光(1064nm、532nm波长)治疗128例色素增多性皮肤病，观察并分析其疗效和美容效果。结果：Q开关Nd：YAG激光治疗色素增多性皮肤病的治疗有效。其中对文眉、雀斑、脂溢性角化、色素痣等总有效率为96％以上，治疗次数为1-4次。结论：Q开关Nd：YAG激光治疗色素增加性皮肤病特别是错误文眉治疗效果好。     

CO2激光结合Nd:YAG激光治疗色素痣的临床观察

目的：评价CO2激光结合Nd：YAG激光治疗色素痣的疗效。方法：先用CO2激光选择连续脉冲，小功率输出，烧灼皮损到周围正常皮肤水平，继之用Nd：YAG激光治疗，治疗面部色素痣128例、768个皮损。结果：Ⅰ、Ⅱ级(痊愈 显效)率为96．76％。治疗次数平均为1.32次。结论：采用CO2激光结合Nd：YAG激光治疗面部色素痣疗效肯定，治愈率高，疗程短。多数患者无明显瘢痕形成。     

Q-开关Nd:YAG激光治疗太田痣疗效观察

目的观察Q－开关Nd：YAG（1064nm）激光对太田痣的治疗效果方法用波长1064nm、脉宽10ns的激光治疗200例太田痣,治疗次数最少1次,最多5次,平均治疗间隔时间4.26月。结果：治疗1次有效率为65．00％,治疗2次、3次显效率分别为53．06％、82．05％,治疗4次、5次治愈率分别为44.44、80．00％,显示治愈率随治疗次数增加而提高。结论：Q－开关Nd：YAG（1064nm）激光治疗太田痣近期疗效可靠,安全、无瘢痕,美容效果显著,操作简便,是目前较理想的治疗方法     

Q开关Nd:YAG激光不同波长治疗面部毛细血管扩张疗效比较

目的：观察Q开关Nd：YAG激光不同波长治疗面部毛细血管扩张的疗效及副反应。方法：128例病人按治疗波长随机分为532nm组75例，585nm组53例，治疗光斑2．0mm，能量密度2．2-6．8J／cm。，脉宽10ns；术后3个月根据术前照片判定疗效，标准分为Ⅳ级。结果：治疗次数1-4次，间隔时间3-5个月，两组共治愈71例(55，47％)，疗效与治疗次数成正相关。其中532nm组治愈36例(48．00％)，平均治愈次数2．64次；585nm组治愈35例(66．04％，)，平均治愈次数2．40次，两组痊愈率及副反应差异无显性。结论：Q开关Nd:YAG激光倍频532／nm和585nm两种波长对密度较低、直径较细的面部毛细血管扩张均有可靠疗效，术后除色素沉着发生较高外，其他不良反应较少。     

Q开关Nd∶YAG激光治疗颧部褐青色痣350例疗效观察

目的 观察Q开关Nd：YAG激光治疗颧部褐青色痣的疗效及不良反应。方法 用波长为倍频532nm，光斑3．0mm，脉宽5～10ns，能量密度1.6～1.8J／cm^2，脉冲频率5～10Hz治疗350例,术后3～6个月复诊，根据术前照片判定疗效，标准分Ⅳ级。结果 治疗次数最少1次，最多5次，共治愈133例(38．0％)，平均治愈次数2．1次，总有效率82．0％，疗效与治疗次数成正相关。结论 Q开关Nd：YAG激光波长为倍频532nm对颧部褐青色痣有很好疗效，一般治疗2～4次可基本痊愈。术后除部分病例色素沉着外，未见不良反应及并发症。     

Q开关激光治疗双侧面部获得性太田痣样斑287例疗效分析

目的：比较Q开关紫翠宝石755nm激光、Nd：YAG1064nm激光和倍频Nd：YAG532nm激光对双侧获得性太田痣样斑的治疗效果和副作用。方法：运用Q开关紫翠宝石755nm激光、Nd：YAG1064nm激光和倍频Nd：YAG532nm激光分别对287例患者进行治疗。结果：经过1～13次治疗后,痊愈140例,显效66例,有效59例,无效22例,总有效率71.8%,总治愈率48.8%。倍频Nd：YAG532nm激光治疗起效快而副反应明显,Q开关紫翠宝石755nm激光和Nd：YAG1064nm激光起效慢但副反应轻微。结论：三种Q开关激光均能有效治疗双侧获得性太田痣样斑,长程低能量的Q开关紫翠宝石755nm激光和Nd：YAG1064nm激光因副反应轻微更适合美容患者的需要。     

Q-Nd:YAG激光治疗色素性皮肤病变疗效观察

目的：Q－Nd:YAG激光治疗色素性皮肤病变的效果。方法：应用Q－Nd:YAG激光1064nm,532nm波长对544例色素性皮肤病变进行治疗。结果：总有效率为96％，对色素痣的疗效欠佳。结论：采用Q－Nd:YAG激光治疗色素性皮肤病变具有效果显著，副作用少的特点，为目前理想的治疗方法。     

Q开关Nd: YAG激光治疗颧部褐青色痣280例

目的：观察Q开关Nd：YAG激光治疗颧部褐青色痣的临床疗效及不良反应。方法：应用Q开关Nd：YAG激光治疗280例患者，波长为1064nm，光斑直径3～4mm，能量密度9～11J／cm^2，脉宽10ns。术后3～6个月复诊，根据术前术后照片判定疗效，标准分为Ⅳ级。结果：治疗1～5次，间隔时间3～12个月，共治愈107例（38．2％），平均治疗次数2．7次，总有效率77．9％，疗效与治疗次数成正相关。术后色素沉着152例（54．3％）。结论：Q开关Nd：YAG激光治疗颧部褐青色痣效果满意，虽然术后色素沉着发生率较高，但均能随时间逐渐消退，未见其他不良反应及并发症。     

三种红外波长激光治疗面部草莓状血管瘤的疗效

目的对比观察3种红外波长激光治疗小儿面部草莓状血管瘤（strawberry hemangiogila．SH）的疗效及容貌结果。方法5～12岁面部SH患儿300例．随机分为半导体激光组,Nd：YAG激光组和CO2激光组,每组100例。3组治疗参数相同（功率10W、光斑直径0．2cm、功率密度318W／cm2）,根据皮损面积大小,半导体激光组和Nd：YAG激光组分别行非接触式扫描凝固术．CO2激光组行气化术。治疗后6个月复查评定疗效及容貌结果。结果治愈率半导体激光组89％,Nd：YAG激光组83％。CO2激光组69％（P〈0．05）;容貌优良率CO2激光组87．0％,半导体激光组86．5％,Nd：YAG激光组57．8％（P〈0．01）;平均治疗次数、治疗时间和治疗中出血量半导体激光组均少于Nd：YAG激光组和CO2激光组（P〈0．01）。结论波长830nm的半导体激光（功率密度318W／cm2）,治疗小儿面部SH具有1次治愈率高、治疗时间短、治疗中出血少和容貌结果好等优点,为治疗小儿面部SH的首选方法。     

调Q Nd：YAG脉冲激光和二氧化碳激光治疗面部色素痣疗效对比观察

目的：观察调QNd：YAG脉冲激光和二氧化碳激光治疗面部色素痣的临床疗效与美容效果。方法：将315例门诊患者随机分成两组：甲组167例,采用调QNd：YAG脉冲激光治疗,波长1064nm,光斑2～3mm,能量密度4。0～4．2J／cm2,频率1～2Hz,点射至肉眼观无黑色组织;乙组148例,采用二氧化碳激光治疗,连续扫射至肉眼观无黑色组织,观察皮损祛除与瘢痕情况。结果：甲组治疗有效率97．97％,乙组治疗有效率97．00％,两组相比P〉0．05,没有统计学差异;甲组瘢痕出现率64．07％,乙组瘢痕出现率为75．00％,两组瘢痕出现率比较,P〈0．05,有统计学差异;甲组中,不同疹型间痊愈率和瘢痕出现率比较均P〈0．05,有统计学差异。结论：调ONd：YAG脉冲激光治疗面部色素痣与二氧化碳激光相比,美容效果优于后者;调QNd：gAG脉冲激光对斑疹型色素痣的疗效优于丘疹型色素痣。     

LASER TREATMENT OF PHARYNGEAL POUCH

The symptoms of pharyngeal pouch become more troublesome, eventually requiring surgical treatment. Excision of the pouch and cricopharyngeal myotomy through a neck incision was the operation of choice until Dohlman described endoscopic diathermy operative treatment 30 years ago.' The diathermy technique has been largely superseded by endoscopic microsurgical division of the cricopharyngeus muscle in the party wall using carbon dioxide laser. This operation is now established as a precise, accurate and safe procedure providing reliable relief of symptoms with minimal risk to the patient. Fifteen patients treated by the microsurgical laser procedure in the past 5 years am reported.     

超脉冲CO2激光眼袋整复术120例分析

目的：总结分析超脉冲CO2激光用于眼袋整复术的临床疗效。方法：用超脉冲CO2激光对120例不同类型的眼袋患者采取经结膜入路或经皮肤入路分别进行眼袋整复术。结果：超脉冲CO2激光眼袋整复术术后满意率达99．2％。结论：用超脉冲CO2激光进行眼袋整复术可提高疗效，减少并发症的发生。     

LASER THERAPY FOR MULTIPLE BlLlARY PAPILLOMATOSIS VIA CHOLEDOCHOSCOPY

Background: Multiple biliary papillomatosis is a rare tumour of the biliary tract but is capable of multicentric malignanttransformation. The complete removal of these tumours is difficult because it involves a field change of the biliary tract. Methods: Exploration with choledochoscopy is a prerequisite for thorough assessment of the extent of involvement. Incorporation of laser ablation via a laser-delivering fibre with choledochoscopy permits complete removal of the tumour. Results: Repeated laser therapy via choledochoscopy through the T-tube tract enables complete ablation of the tumour which changes the outlook of the prognosis. This is confirmed on subsequent cholangiography. Conclusions: Laser therapy via choledochoscopy is a satisfactory mode of treatment for multiple biliary papillomatosis. It enables complete and precise ablation of the tumour which certainly changes the prognosis of this condition.     

585nm脉冲染料激光治疗顽固的病毒性疣

目的：探讨一种治疗顽固的病毒性疣的有效治疗方法。方法：用５８５ｎｍ的脉训染料激光（ＰＤＬ）照射患区及其周围５ｍｍ内的区域连续三个脉冲，能量范围６～９Ｊ／ｃｍ＾２，照射前先用最小能量连续脉冲的ＣＯ２激光除去疣表面的角质层，以使ＰＤＬ光进入更深层。结果：治疗３８例病人１６３个顽固性疣和３０个单纯性疣，根治率分别为９５％及９０％，经过３～２６个月（平均８个月）的随访，未再复发。结论：利用疣内血管中的血红     

铒激光在治疗面部皱纹中的应用

目的：观察新型铒激光治疗黄种人皮肤皱纹的效果及安全性。方法：用铒激光对黄种人的面部皮肤进行磨皮除皱手术共35例，观察除皱效果，术后反应及并发症。结果：面部细小皱纹一次治疗即可基本去除，较深的皱纹也可明显减轻甚至消失，疗效显著。术后疼痛轻微，红斑消退快，色素沉着率为37．1％，2月后色素沉着均有明显减轻，6月内色素沉着全部消退。无1例出现局部色素减退及瘢痕现象。结论：新型铒激光磨皮不失为黄种人面部除皱的良好方法，其疗效好且上皮再生恢复快，红斑期短，副作用小。     

胆道镜激光碎石治疗胆道结石嵌顿

目的 探讨术中胆道镜下激光碎石在治疗胆道结石嵌顿的临床价值。方法 回顾分析2005年8月至2007年12月术中肝胆管结石及胆总管结石嵌顿的临床资料。结果术中使用激光碎石后,胆总管结石组无胆管损伤,无残石病例;肝胆管结石组2例术后残石者均经T管窦道取出,残石1例,最终残石率为6．25％。结论 胆道镜下激光碎石在治疗胆道结石嵌顿具有直观、准确、方便、疗效确切的特点,是降低残石率避免更人手术创伤的重要手段。     

LASER PHOTOCOAGULATION IN THE TREATMENT OF MALIGNANT DYSPHAGIA

Background : Dysphagia secondary to carcinoma of the oesophagus and gastric cardia is the principal symptom requiring palliation in those patients who present with late-stage disease or who are unfit for surgery. The primary aim of the present study was to determine the safety and efficacy of laser photocoagulation in the palliation of malignant dysphagia. Secondary aims were to look at reasons for failure and predictors of outcome; to determine the most appropriate second line therapy for treatment failures; and to look at the results of treatment for early stage disease. Methods : Sixty-seven patients treated over a 6-year period with endoscopic Nd:YAG laser photocoagulation were evaluated and the quality of swallowing assessed before and at intervals after treatment. Results : Ninety per cent of patients achieved successful initial palliation. This was sustained in 76% after 3 months of treatment. Within a month before death 71 % of patients were palliated but 29% required the addition of second-line treatment to achieve this. Complications were infrequent. There were no deaths attributable to laser treatment. Five of 10 patients treated with radiotherapy developed fibrous stricturing that required endoscopic dilatation. No variables were independently predictive for treatment failure. Six patients with early stage disease experienced prolonged survival. Conclusions : We conclude that laser photocoagulation offers safe and effective palliation of malignant dysphagia in this group of patients and is appropriate as first-line therapy.     

超脉冲CO2激光治疗睑黄瘤

目的：观察超脉冲CO2激光治疗睑黄瘤疗效。方法：采用美国科以人公司生产的超脉冲CO2激光机治疗162例睑黄瘤病人，即将激光对准病变组织逐层祛除至正常组织。结果：除56例由于病变范围较大分两次激光治疗，其余均一次性根除，创面愈合良好，皮肤无明显瘢痕，随访半年无复发。结论：采用这种方法治疗睑黄瘤是目前较理想的治疗方法。     

INTERSTITIAL LASER COAGULATION FOR BENIGN PROSTATIC HYPERPLASIA: PRELIMINARY CLINICAL RESULTS

We report our early experience in the clinical application of interstitial laser coagulation of the prostate (ILCP) in the treatment of benign prostatic hyperplasia (BPH). Neodymium: YAG laser energy is transmitted via a specially designed interstitial thermotherapy light-guide. The light guides were inserted transurethrally into each lobe of the prostate by direct puncture, under direct visualization. The prostatic urethra is preserved during the procedure. From December 1993 to March 37 patients with symptomatic BPH were treated with ILCP. Treatment outcome was evaluated by the International Prostatic Symptom Score (I-PSS), flow rate, postvoided residual urine volume and quality of life score. Significant improvement in I-PSS and peak flow rate was observed at 3 months: I-PSS decreased from a mean of 19.3 to 10. and the peak flow rate increased from a mean of 7.2 to 9.4 ml/sec (p < 0.0001). The mean postvoided residual urine volume significantly decreased from 91 to 47 ml (p < 0.01). Two days after ILCP the serum prostate-specific antigen had increased by 860%, evidence of the significant tissue damage produced by laser irradiation. The quality of life score significantly decreased from a mean of 4.8 to 2.1 (p < 0.0001). No serious side-effects were observed. The early clinical results suggest that ILCP is safe and effective as a treatment of BPH and is less invasive than some other methods.     

低能量氦-氖激光血管内照射治疗皮肤撕脱伤疗效观察

目的 探讨低能量氦（Ｈｅ）－氖（Ｎｅ）激光血管内照射对撕脱皮瓣原位回植术后皮瓣成活的影响,方法 选择伤后６小时内行清创、撕脱瓣原位回植术撕脱伤患者５８例,其中治疗组３１例应用能量Ｈｅ－Ｎｅ激光血管内照射加常规治疗;对照组２７例仅用常规治疗。结果 术后１５天治疗组撕脱瓣的成活面积、成活质量均明显优于对照组（Ｐ〈０．０５）,治疗组血液流变学参数变化在术后５天内最明显。结论 低能量Ｈｅ－Ｎｅ激光血管内照