安氏Ⅱ类2分类错(牙合)与先天性牙异常的关系

目的:为了验证安氏Ⅱ类2分类错(牙合)与先天性牙异常如过小侧切牙、釉质发育不良、多生牙、易位牙、尖牙阻生和缺牙之间存在的关系.方法:对100例年龄12～42岁未经历正畸治疗的Ⅱ类2分类错(牙合)患者的病史、口内、X片和牙模型进行检查,并进行样本百分比分析.结果:结果显示牙异常者占50.00%.7.00%的患者上侧切牙釉质发育不良,28.00%过小侧切牙,4.00%尖牙阻生,9.00%下切牙缺失,易位牙为2.00%,无一例多生牙.30.00%前牙Bolton比值不协调.结论:安氏Ⅱ类2分类错(牙合)与过小侧切牙、釉质发育不良、先天缺牙密切相关.Ⅱ类2分类错(牙合)前牙Bolton比值不协调的主要因素是过小侧切牙和下切牙缺失.     

安氏II类2分类错He与先天性牙异常的关系

目的：为了验证安氏II类2分类错He与先天性牙异常如过小侧切牙、釉质发育不良、多生牙、易位牙、尖牙阻生和缺牙之间存在的关系。方法：对100例年龄12～42岁未经历正畸治疗的II类2分类错He患者的病史、口内、X片和牙模型进行检查，并进行样本百分比分析。结果：结果显示牙异常者占50．00％。7．00％的患者上侧切牙釉质发育不良，28．00％过小侧切牙，4．00％尖牙阻生，9．00％下切牙缺失，易位牙为2．00％，无一例多生牙。30．00％前牙Bolton比值不协调。结论：安氏II类2分类错He与过小侧切牙、釉质发育不良、先天缺牙密切相关。II类2分类错He前牙Bolton比值不协调的主要因素是过小侧切牙和下切牙缺失。     

十堰地区错畸形患者Bolton指数的测量

目的:分析十堰地区各类错牙合畸形患者Bolton指数及Bolton指数不调发生率的差异。方法:随机选择3 2 5例不同类型错牙合畸形患者的记存模型,分别测量上、下颌全牙量和前牙量,计算Bolton指数值及Bolton指数不调的发生率,进行统计学分析。结果:安氏Ⅰ类和安氏Ⅲ类错牙合前牙Bolton指数及全牙弓Bolton指数均大于安氏Ⅱ类1分类错牙合病例,且具有统计学差异(P <0 .0 5 ) ;安氏Ⅰ类错牙合Bolton指数不调发生率大于安氏Ⅱ类1分类及安氏Ⅱ类2分类,安氏Ⅲ类错牙合Bolton指数不调发生率大于安氏Ⅱ类1分类错牙合病例,有统计学差异。结论:不同类型错牙合畸形病例的Bolton指数及Bolton指数不调发生率有统计学差异,正畸治疗前进行Bolton指数分析非常重要。     

安氏Ⅱ类错(牙合)畸形牙冠宽度和Bolton指数测量分析

目的 分析安氏Ⅱ类错(牙合)畸形患者的Bolton指数,并探讨其上下牙量关系对其症状及疗效的影响.方法 以安氏Ⅱ类1分类和2分类错(牙合)畸形患者各100例为研究对象,分别进行牙冠宽度测量并计算Bolton指数.结果 安氏Ⅱ类1分类错(牙合)的前牙宽度比安氏Ⅱ类2分类错(牙合)大,差异有统计学意义.Bolton指数不调的基本分布情况为:指数正常组＞指数过小组＞指数过大组.Bolton指数前牙比和全牙比呈现安氏Ⅱ类2分类错(牙合)＞安氏Ⅱ类1分类错(牙合),但其差异无统计学意义.结论 安氏Ⅱ类错(牙合)中有约50％病例Bolton指数在正常值范围之外,存在上下牙量不协调.     

安氏Ⅱ类2分类错(牙合)与先天性下切牙异常的关系

目的 探讨安氏Ⅱ类2分类错(牙合)患者下切牙的特点,为矫治安氏Ⅱ类2分类错(牙合)提供参考.方法 对126例年龄11～18岁正畸治疗前的安氏Ⅱ类2分类错(牙合)牙模型进行测量,分析安氏Ⅱ类2分类错(牙合)患者下切牙牙量和缺失情况.结果 安氏Ⅱ类2分类错(牙合)患者10.32%下切牙缺失,下颌中切牙牙冠近远中宽度平均为5.21 mm,下颌侧切牙牙冠近远中宽度平均为5.76 mm,与文献正常值比较显示下切牙偏小,经统计学分析差异有统计学意义(P＜0.01).结论 安氏Ⅱ类2分类错(牙合)患者下切牙牙冠的近远中径较正常人小,且多发下切牙缺失.     

安氏Ⅰ、Ⅱ、Ⅲ类错(牙合)患者Bolton不调量的分析

目的了解安氏错(牙合)患者上下颌Bolton不调量的大小及发生率.方法 选择439例安氏错（牙合）患者的模型,分别测量上下颌6个前牙(左右恒尖牙之间)及12个恒牙(左右第一恒磨牙之间)的牙冠近远中宽度总和,根据Bolton指数正常值获取上颌Bolton不调量并作统计学分析.结果 439例安氏Ⅰ、Ⅱ、Ⅲ类错（牙合）患者中,前牙或全牙Bolton不调量绝对值大于或等于1.5 mm的错（牙合）患者占该类患者的百分比分别为14.02%、9.49%、19.32%或19.63%、15.33%、20.45%.安氏Ⅰ类错(牙合)患者前牙Bolton不调量以上前牙牙量减少、下前牙牙量增多为常见;安氏Ⅱ类、Ⅲ类错(牙合)患者,前牙或全牙Bolton不调者上颌和下颌牙量偏多偏少,差异无显著性.结论 错(牙合)患者Bolton不调不是引起错(牙合)发生的主要原因.     

十堰地区错(牙合)畸形患者Bolton指数的测量

目的:分析十堰地区各类错(牙合)畸形患者Bolton指数及Bolton指数不调发生率的差异.方法:随机选择325例不同类型错(牙合)畸形患者的记存模型,分别测量上、下颌全牙量和前牙量,计算Bolton指数值及Bolton指数不调的发生率,进行统计学分析.结果:安氏Ⅰ类和安氏Ⅲ类错(牙合)前牙Bolton指数及全牙弓Bolton指数均大于安氏Ⅱ类1分类错(牙合)病例,且具有统计学差异(P<0.05);安氏Ⅰ类错(牙合)Bolton指数不调发生率大于安氏Ⅱ类1分类及安氏Ⅱ类2分类,安氏Ⅲ类错(牙合)Bolton指数不调发生率大于安氏Ⅱ类1分类错(牙合)病例,有统计学差异.结论:不同类型错(牙合)畸形病例的Bolton指数及Bolton指数不调发生率有统计学差异,正畸治疗前进行Bolton指数分析非常重要.     

十堰地区错畸形患者Bolton指数的测量

目的分析十堰地区各类错(牙合)畸形患者Bolton指数及Bolton指数不调发生率的差异.方法随机选择325例不同类型错(牙合)畸形患者的记存模型,分别测量上、下颌全牙量和前牙量,计算Bolton指数值及Bolton指数不调的发生率,进行统计学分析.结果安氏Ⅰ类和安氏Ⅲ类错(牙合)前牙Bolton指数及全牙弓Bolton指数均大于安氏Ⅱ类1分类错(牙合)病例,且具有统计学差异(P<0.05);安氏Ⅰ类错(牙合)Bolton指数不调发生率大于安氏Ⅱ类1分类及安氏Ⅱ类2分类,安氏Ⅲ类错(牙合)Bolton指数不调发生率大于安氏Ⅱ类1分类错(牙合)病例,有统计学差异.结论不同类型错(牙合)畸形病例的Bolton指数及Bolton指数不调发生率有统计学差异,正畸治疗前进行Bolton指数分析非常重要.     

安氏Ⅱ类错(牙合)的牙冠宽度与Bolton指数的测量分析

目的:通过对安氏Ⅱ1类及安氏Ⅱ2类错(牙合)与正常(牙合)模型比较,分析上下颌牙冠宽度、Bolton指数差异,为安氏Ⅱ类错(牙合)矫治设计提供参考.方法:以正常(牙合),安氏Ⅱ1及安氏Ⅱ2错(牙合)各40例为研究对象,分别进行牙冠宽度测量并计算Bolton指数.结果:①安氏Ⅱ1错(牙合)的上下颌侧切牙及第二前磨牙的牙冠宽度比正常(牙合)大,并有显著性差异.②Bolton指数前牙比及全牙比:正常(牙合)＞安氏Ⅱ2错(牙合)>安氏Ⅱ1错(牙合).③正常(牙合)上下颌前牙牙量的直线回归方程:Y=X 10.45;全牙列的直线回归方程:Y=1.13X-2.57.结论:上下颌牙量不调是造成安氏Ⅱ类错(牙合)深覆盖、深覆(牙合)的因素之一;前牙量及全牙量的线性回归方程具有较高的临床应用价值.     

上颌中切牙与尖牙同时阻生的临床特征分析

目的分析上颌中切牙与同侧尖牙同时阻生病例的临床特征。方法选择上颌中切牙与同侧尖牙同时阻生病例21例,分析上颌中切牙阻生类型与尖牙阻生情况,测量阻生侧及对侧侧切牙发育或萌出异常情况。结果与中切牙阻生同时发生的尖牙76.2%为唇侧阻生,其中完全易位与不完全易位占唇侧阻生尖牙的68.8%,尖牙唇侧阻生病例中侧切牙根远中倾斜和伴牙冠近中倾斜者占87.5%,尖牙唇侧或腭侧阻生病例中,出现锥形或过小等畸形侧切牙的比例分别为31.25%和40.00%。上颌中切牙与尖牙不同阻生类型患者,前牙反牙合比例都超过40%,且多为牙型反牙合。结论与中切牙阻生同时发生的尖牙阻生多为唇侧阻生,与中切牙阻生类型无关,与侧切牙根远中倾斜高度相关,尖牙完全易位与过小或锥形等畸形侧切牙有关。     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31–82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL‐QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non‐dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non‐dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non‐dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health.     

拔牙位点保存用复合温敏凝胶的构建及体外表征

目的:制备多壁碳纳米管/羟基磷灰石/壳聚糖复合温敏凝胶,探讨其作为拔牙位点保存材料的理化性能。方法:采用原位沉积方法制备多壁碳纳米管/羟基磷灰石(MWNT/ HA简称HAC)复合无机材料,将其分散至壳聚糖温敏凝胶中,制备壳聚糖/多壁碳纳米管/羟基磷灰石(CS /MWNT/HA简称CS/HAC)复合温敏凝胶,以成胶时间、孔径、孔隙率、机械强度及降解性能为指标优化配方设计,并表征复合温敏凝胶的微观形貌及理化性能。结果:以10 g/L的HAC作为补强成分加入到壳聚糖溶液中,能够在不影响成胶并保证一定孔隙率(84%)的前提下,提高材料的机械性能(抗压强度0.441 MPa),所获复合温敏凝胶具有适宜的临床操作时间(12 min),并具有可控的降解速率。结论:负载HAC的复合温敏凝胶具有良好的成型性,并具有较好的机械性能,在拔牙位点保存领域具有良好的应用前景。     

Interventional neuroradiologic procedures in the head and neck

Interventional radiology and interventional neuroradiology are evolving specialties which can aid the head and neck surgeons in the clinical management of patients with complex vascular lesions.