The 12-item General Health Questionnaire (GHQ-12): translation and validation study of the Iranian version

Background  

The objective of this study was to translate and to test the reliability and validity of the 12-item General Health Questionnaire (GHQ-12) in Iran.     

The Iranian version of 12-item Short Form Health Survey (SF-12): factor structure, internal consistency and construct validity

Background  

The 12-item Short Form Health Survey (SF-12) as a shorter alternative of the SF-36 is largely used in health outcomes surveys. The aim of this study was to validate the SF-12 in Iran.     

Rethinking and rescoring the SF-12

Objectives  

To derive and assess the validity of an Australian version of the SF-12 quality-of-life questionnaire.     

Modification of the asthma quality of life questionnaire (standardised) for patients 12 years and older

Background  

The age limit for some adult asthma clinical trials has recently been lowered to 12 years. In this study we have made minor modifications to the standardised version of the adult Asthma Quality of Life Questionnaire (AQLQ(S)) to make it valid for patients 12 years and older (AQLQ12+).     

A Rasch and confirmatory factor analysis of the General Health Questionnaire (GHQ) - 12

Background  

The General Health Questionnaire (GHQ) - 12 was designed as a short questionnaire to assess psychiatric morbidity. Despite the fact that studies have suggested a number of competing multidimensional factor structures, it continues to be largely used as a unidimensional instrument. This may have an impact on the identification of psychiatric morbidity in target populations. The aim of this study was to explore the dimensionality of the GHQ-12 and to evaluate a number of alternative models for the instrument.     

The reliability of the twelve-item general health questionnaire (GHQ-12) under realistic assumptions

Background  

The twelve-item General Health Questionnaire (GHQ-12) was developed to screen for non-specific psychiatric morbidity. It has been widely validated and found to be reliable. These validation studies have assumed that the GHQ-12 is one-dimensional and free of response bias, but recent evidence suggests that neither of these assumptions may be correct, threatening its utility as a screening instrument. Further uncertainty arises because of the multiplicity of scoring methods of the GHQ-12. This study set out to establish the best fitting model for the GHQ-12 for three scoring methods (Likert, GHQ and C-GHQ) and to calculate the degree of measurement error under these more realistic assumptions.     

The 12-item medical outcomes study short form health survey version 2.0 (SF-12v2): a population-based validation study from Tehran,Iran

Background  

The SF-12v2 is the improved version of the SF-12v1. This study aimed to validate the SF-12v2 in Iran.     

Confirmatory factor analysis of the validity of the SF-12 for persons with and without a history of stroke

Purpose  

To assess the validity of the Physical and Mental Component Summary scores (PCS and MCS) of the 12-item Short-Form Health Survey (SF-12), a measure of health-related quality of life (HRQoL), among persons with a history of stroke.     

Correlated physical and mental health summary scores for the SF-36 and SF-12 Health Survey, V.1

Background  

The SF-36 and SF-12 summary scores were derived using an uncorrelated (orthogonal) factor solution. We estimate SF-36 and SF-12 summary scores using a correlated (oblique) physical and mental health factor model.     

Validation of the AQLQ12+ among adolescents and adults with persistent asthma

Background  

To date, there is limited psychometric evidence on the Asthma Quality of Life Questionnaire (AQLQ12 +) among populations that include adolescents and adults.     

Comparing the SF-12 and SF-36 health status questionnaires in patients with and without obesity

Objective  

To assess how well the SF-36, a well-validated generic quality of life (QOL) instrument, compares with its shorter adaptation, the SF-12, in capturing differences in QOL among patients with and without obesity.     

Impacts of recurrent aphthous stomatitis on quality of life of 12- and 15-year-old Thai children

Purpose  

To assess the prevalence and characteristics of oral impacts attributed to recurrent aphthous stomatitis (RAS) in 12- and 15-year-olds Thais.     

The role of interleukin-12 in the heavy metal-elicited immunomodulation: relevance of various evaluation methods

Background  

Increasing evidence exists that heavy metals modulate T helper cell (Th) responses and thereby elicit various pathological manifestation. Interleukin (IL)-12, a crucial innate cytokine, was found to be regulated by such xenobiotic agents. This study aimed at testing whether IL-12 profiles may be indicative of heavy metals-induced immunomodulation.     

Validity of SF-12 summary scores in a Greek general population

Background  

The 12-item Health Survey (SF-12) was developed as a shorter alternative to the SF-36 for use in large-scale studies, particularly when overall physical and mental health are the outcomes of interest instead of the typical eight-scale profile. The main purpose of this study was to assess the validity of the Greek version of the SF-12.     

Changes in skinfold thickness and waist circumference after 12 and 24 months resulting from the NHF-NRG In Balance-project

Background  

More knowledge is needed regarding the effectiveness of weight gain prevention programmes. The present study tested the 12-and 24-month effectiveness of the 'Netherlands Research programme weight Gain prevention' (NHF-NRG)-In Balance-project, a worksite-based intervention aimed at the prevention of weight gain.     

The internal consistency and construct validity of the partners in health scale: validation of a patient rated chronic condition self-management measure

Purpose  

The purpose of this study was to test the internal consistency and construct validity of the revised 12-item self-rated Partners in Health (PIH) scale used to assess patients’ chronic condition self-management knowledge and behaviours.     

Long-term follow-up of beryllium sensitized workers from a single employer

Background  

Up to 12% of beryllium-exposed American workers would test positive on beryllium lymphocyte proliferation test (BeLPT) screening, but the implications of sensitization remain uncertain.     

Transcobalamin-II variants,decreased vitamin B12 availability and increased risk of frailty

Objective  

This project was designed to follow-up prior evidence that demonstrated a significant association between vitamin B₁₂ transport and metabolism and the frailty syndrome in community-dwelling older women. The cross-sectional relationship between genetic variants within six candidate genes along this pathway with serum methylmalonic acid (MMA) levels and frailty was evaluated in this same population of older women.     

Vitamin B12 deficiency in Australian residential aged care facilities

Objective  

To determine the prevalence of undiagnosed vitamin B12 deficiency among residential aged care facility residents in southern Tasmania, Australia, and to identify associated risk factors.     

Mental health (GHQ12; CES-D) and attitudes towards the value of work among inmates of a semi-open prison and the long-term unemployed in Luxembourg

Aim  

To analyse the relationships between mental health and employment commitment among prisoners and the long-term unemployed (LTU) trying to return to work.