共查询到4条相似文献,搜索用时 2 毫秒
1.
I. Ziv Ruth Djaldetti Yoseph Zoldan Marian Avraham Eldad Melamed 《Journal of neurology》1998,245(12):797-802
The differentiation of “non-organic” limb weakness from genuine paralysis is sometimes difficult in neurological practice.
To address this problem, we developed a computerized quantitative method, based on the Hoover’s test principle, that determines
the extent of involuntary limb activation when contralateral movement is performed. Measurements of hip or arm extension isometric
force are performed during direct maximal voluntary effort and during contralateral hip flexion. Maximal involuntary/voluntary
force ratio (IVVR) is calculated. IVVR of the lower limbs in ten healthy subjects was 0.614, 0.044 (mean, SEM). Similar results
were obtained from seven patients with genuine weakness and in the non-affected limbs of nine patients with “non-organic”
mono- or hemiparesis. In contrast, IVVR in the affected limbs in the “non-organic” group was markedly increased (2.48, 0.61;
P < 0.001). The same pattern was elicited in the upper limbs (2.27, 0.46 vs 0.406, 0.06; P < 0,001). We conclude that Hoover’s sign in “non-organic” paralysis is a preservation or increase of a normal synkinetic
phenomenon. Quantitative measurement of the IVVR can serve as a useful ancillary test in diagnosing non-organic weakness in
either lower or upper limbs.
Received: 10 March 1997 Received in revised form: 21 April 1998 Accepted: 28 April 1998 相似文献
2.
AbstractWe used spectral electroencephalographic (EEC) analysis to demonstrate the physiological effect of focal brain ischaemia induced by permanent occlusion of the right middle cerebral artery in rats. A significant shift to lower frequency EEC activity occurred relative to the baseline power spectrum within one hour following the occlusion. Spectral EEG analysis also revealed a cerebroprotective effect of a noncompetitive N-methyl-D-aspartate receptor antagonist, CNS 1102, administered 15 min post-occlusion. Animals treated with this NMDA antagonist exhibited only 26.5% of the slowing in the ischaemic hemisphere compared to aminals given a placebo. Post-mortem analysis conducted 24 h later also revealed reduced infarction volumes for the treated animals, there was a highly significant correlation between the extent of spectral EEG slowing during the initial development of the infarction and subsequent lesion size. These results suggest that spectral EEG analysis may be useful in the early evaluation of experimental and perhaps human stroke and for monitoring the effects of cerebroprotective therapies. [Neurol Res 1994; 16: 443-448] 相似文献
3.
Tommaso Fedele Georgia Ramantani Sergey Burnos Peter Hilfiker Gabriel Curio Thomas Grunwald Niklaus Krayenbühl Johannes Sarnthein 《Clinical neurophysiology》2017,128(7):1220-1226
Objective
Fast ripples (FR, 250–500 Hz) in the intraoperative corticogram have recently been proposed as specific predictors of surgical outcome in epilepsy patients. However, online FR detection is restricted by their low signal-to-noise ratio. Here we propose the integration of low-noise EEG with unsupervised FR detection.Methods
Pre- and post-resection ECoG (N = 9 patients) was simultaneously recorded by a commercial device (CD) and by a custom-made low-noise amplifier (LNA). FR were analyzed by an automated detector previously validated on visual markings in a different dataset.Results
Across all recordings, in the FR band the background noise was lower in LNA than in CD (p < 0.001). FR rates were higher in LNA than CD recordings (0.9 ± 1.4 vs 0.4 ± 0.9, p < 0.001). Comparison between FR rates in post-resection ECoG and surgery outcome resulted in positive predictive value PPV = 100% in CD and LNA, and negative predictive value NPV = 38% in CD and NPV = 50% for LNA. Prediction accuracy was 44% for CD and 67% for LNA.Conclusions
Prediction of seizure outcome was improved by the optimal integration of low-noise EEG and unsupervised FR detection.Significance
Accurate, automated and fast FR rating is essential for consideration of FR in the intraoperative setting. 相似文献4.
Sarolta Leé Katarina VargováIstván Hizoh Zsófia HorváthPetra Gulácsi-Bárdos Zsófia SztupinszkiAnna Apró Andrea KovácsIstván Préda Emese Tóth-ZsámbokiRóbert G. Kiss 《Thrombosis research》2014
The benefit of adjusted antiplatelet therapy in patients with myocardial infarction after primary percutaneous coronary intervention is not well elucidated. We aimed to identify patients with high on treatment platelet reactivity and to gradually adjust antiplatelet therapy. 相似文献