共查询到4条相似文献，搜索用时 0 毫秒
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Jennifer Loyden Potter Bruce K. Schefft Dean W. Beebe Steven R. Howe Hwa-shain Yeh Michael D. Privitera 《Epilepsy & behavior : E&B》2009,16(2):246-253
We sought to determine significant predictors of seizure and cognitive outcome following surgery for epilepsy. Participants included 41 patients who had undergone anterior temporal lobectomy (ATL). Higher presurgical verbal/language scores and lower nonverbal memory scores were predictive of seizure-free status following ATL. Overall, the presurgical predictors were 93% accurate in discriminating between seizure-free and non-seizure-free patients postsurgery. Surgery in the nondominant-for-language hemisphere was predictive of higher postsurgical verbal/language and verbal memory scores. Higher presurgical visual/construction, nonverbal memory, and verbal/language scores were predictive of better postsurgical verbal/language functioning. Better presurgical verbal/language functioning was predictive of the same skills postsurgically as well as visual/construction outcomes. Exploratory analyses in a subset of participants (n = 25) revealed that dominant and nondominant intracarotid amobarbital (Wada) memory scores added unique variance only for predicting nonverbal memory following ATL. Presurgical neuropsychological testing provides significant and unique information regarding postsurgical seizure freedom and cognitive outcome in patients who have undergone ATL. 相似文献
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Gopal Krishna Dash Chaturbhuj Rathore Malcolm K. Jeyaraj Pandurang Wattamwar Sankara P. Sarma Kurupath Radhakrishnan 《Clinical neurophysiology》2018,129(5):946-951
Objective
Interictal regional paroxysmal fast activity (RPFA) on scalp EEG is common in patients with focal cortical dysplasia (FCD). Little data exists regarding the presence of RPFA in other etiologies.Methods
We studied the association between RPFA and etiology on MRI in patients with drug resistant focal epilepsy undergoing presurgical evaluation in 2011. RPFA was defined as ≥3 consecutive spikes with a frequency of ≥10?Hz lasting ≥300?ms but <4?s.Results
626 patients fulfilled the inclusion criteria. Of these, 138 (22%) patients had RPFA while rest had other interictal epileptiform discharges (IEDs). RPFA was located at posterior head region in 52.2% patients, frontal regions in 24.6% patients and over temporal regions in 17.4% patients. Focal gliosis (61, 44%) and FCD (27, 19%) were common etiologies in patients with RPFA. Compared to patients with other IEDs, patients with RPFA were more likely to have focal gliosis (61/138 vs. 39/488; p?<?0.0001) or FCD (27/138 vs 37/488; p?<?0.001) as the etiology of epilepsy.Conclusion
In developing countries, focal gliosis is more common than FCD as the underlying etiology in patients with RPFA on scalp EEG.Significance
Focal gliosis should be considered as one of the common substrate for RPFA on scalp EEG. 相似文献4.
W.O. Tatum G. Rubboli P.W. Kaplan S.M. Mirsatari K. Radhakrishnan D. Gloss L.O. Caboclo F.W. Drislane M. Koutroumanidis D.L. Schomer D. Kasteleijn-Nolst Trenite Mark Cook S. Beniczky 《Clinical neurophysiology》2018,129(5):1056-1082
Electroencephalography (EEG) remains an essential diagnostic tool for people with epilepsy (PWE). The International Federation of Clinical Neurophysiology produces new guidelines as an educational service for clinicians to address gaps in knowledge in clinical neurophysiology. The current guideline was prepared in response to gaps present in epilepsy-related neurophysiological assessment and is not intended to replace sound clinical judgement in the care of PWE. Furthermore, addressing specific pathophysiological conditions of the brain that produce epilepsy is of primary importance though is beyond the scope of this guideline. Instead, our goal is to summarize the scientific evidence for the utility of EEG when diagnosing and monitoring PWE. 相似文献