临床药物中毒的文献回顾性分析

本文通过1980～1994年116种中文医学期刊的中毒文献回顾，总结了20类144种药物中毒的报道，共收集报道的病例871例。通过分析认为，临床上发生的中毒药物主要集中于中枢神经系统类药物和心血管系统类药物，误服药物中毒主要集中儿童和老年人群。     

Prescribing patterns in patients using new antidepressants

AIMS: To study possible selective prescribing ('channelling') we compared characteristics of patients using the SSRI sertraline with patients using longer available SSRIs. METHODS: An observational cohort study in 1251 patients being prescribed an SSRI. RESULTS: In contrast to other studies, we found no evidence for channeling of sertraline. Sertraline was mainly prescribed for the labelled indication (depressive disorder), while older SSRIs were more often prescribed also for other indications. Time on the market was inversely associated to the proportion of patients treated for depressive disorder. CONCLUSIONS: We found no evidence for channeling of sertraline compared with prescribing patterns of older SSRIs.