带血管胎胰及胸腺联合移植对预防Ⅰ型糖尿病并发症的研究

对30例Ⅰ型糖尿病(DDM)患者行带血管胚胎胰腺及胸腺腹腔内联合移植,随防3年以上20例,其中5年9例、4年5例及3年6例。显效14例中3例停用胰岛素,余11例胰岛素平均减量75.2％。有效6例,胰岛素平均减量42.0％。空腹及餐后血糖水平较移植前明显下降(P<0.01);C肽(C-P)水平上升(P<0.01);血清胆固醇(CHO)及甘油三酯(TG)较移植前减低(P<0.05)。5例合并眼底病变者,视网膜微血管瘤消失。3例糖尿病肾病者平均24 h尿白蛋白排出率(UAER)较植前明显减低(<300 mg)。     

经肝动脉移植新生猪胰岛细胞治疗Ⅰ型糖尿病的初步报告

目的　探讨异种胰岛细胞肝内移植临床应用的可行性 ,了解猪胰岛细胞植入糖尿病病人肝内以后是否可控制病人血糖 ,了解移植后可能发生的并发症。方法　培养 7～ 10d的新生猪胰岛细胞 ,经肝动脉植入 4例Ⅰ型糖尿病病人肝内 ;其中 2例植入 4× 10 6个胰岛细胞 ,2例植入 8× 10 6个胰岛细胞。移植后病人使用的抗排斥方案为 :术后当天 ,使用甲泼尼龙 5 0 0mg,第 2天将甲泼尼龙降至 5 0mg ,3d后服用泼尼松并逐步减量至 10mg ,维持该剂量 1个月 ;环孢素 8mg/kg ,每日 2次 ,使用 12个月 ;霉酚酸酯 2g/d ,使用 2 5d。测量移植前后外源性胰岛素用量、葡萄糖耐量试验、血糖以及糖化血红蛋白。观察病人一般情况及肝、肾功能变化。结果　由于使用甲泼尼龙的原因 ,移植后病人的外源性胰岛素用量一度上升至 6 0mg。随着甲泼尼龙用量的减少 ,外源性胰岛素的用量逐渐减少 ,较移植前减量约 32 %～ 5 8%。胰岛素减量幅度与植入胰岛细胞数量相关。移植以后糖尿病病人糖化血红蛋白减少 ,血糖较移植前明显稳定 ,肝肾功能维持正常 ,病人体重增加 ,一般情况改善。移植异种胰岛细胞以后未发现肝功能和外周血CD4阳性淋巴细胞和CD8阳性淋巴细胞异常。结论　经肝动脉移植猪胰岛细胞治疗Ⅰ型糖尿病是安全、有效的治疗方法。所使用的抗     

Masquelet技术联合自体腓骨及髂骨移植治疗慢性骨髓炎伴骨缺损疗效分析

目的 研究探讨Masquelet技术联合自体腓骨及髂骨移植治疗慢性骨髓炎伴骨缺损的临床效果。方法 给予2018年1月至2020年5月玉林市中西医结合骨科医院收治的15例慢性骨髓炎伴骨缺损患者应用Masquelet技术联合自体腓骨及髂骨移植治疗,观察术后切口、骨折与骨缺损愈合情况以及肢体功能恢复情况。结果 术后随访1～2年,15例患者术后切口均甲级愈合;除1例胫骨慢性骨髓炎伴骨缺损患者因过早拆除外固定支架再发骨折外,其余患者骨折部位均愈合,愈合时间为3.0～6.0个月,平均4.5个月。末次随访时,15例患者均能弃拐负重行走,骨缺损愈合等级为优9例、良4例、可2例,优良率为86.7%;肢体功能恢复等级为优10例、良3例、可2例,优良率为86.7%。结论 Masquelet技术联合自体腓骨及髂骨移植治疗慢性骨髓炎伴骨缺损,可有效修复骨缺损,最大程度恢复肢体功能,效果确切,临床应用价值较高。     

自体下颌骨供骨修复下颌骨中大型缺损(附21例报告)

本组下颌骨中大型缺损21例,缺损长度4～14cm,其中>10cm者11例,平均9.2cm。应用自体下颌骨供骨及钛支架联合移植修复14例,自体下颌骨供骨修复7例。随访1 1/2年以上3例,1～1 1/2年10例,1/2～1年4例,小于1/2年4例,外形及功能满意。     

异基因造血干细胞移植治疗儿童血液病

目的造血干细胞移植可以根治白血病、再生障碍性贫血、血红蛋白病及先天性免疫缺陷等疾病,通过临床观察,分析研究异基因造血干细胞移植对儿童血液病的治疗效果。方法采用异基因造血干细胞移植治疗15例儿童血液病,其中非血缘脐血移植9例,同胞脐血移植3例,同胞外周血干细胞移植2例,同胞骨髓移植1例。采用白消安、环磷酰胺或环磷酰胺、全身照射为基础的预处理的方案。结果14例患者植入,1例于移植后15d死亡,未达植入标准。白细胞的植入时间各组间没有明显差异;脐血移植血小板的植入明显较骨髓或外周血延迟（P〈0．05）。主要并发症为巨细胞病毒感染和复发,11例患者生存;其中10例无病存活,占66．7％,存活最长时间为6年。Kaplan-Meier生存曲线提示：1年生存率为76．6％,预计5年生存率为57．4％。结论脐血移植具有移植物抗宿主疾病轻、较容易控制、搜寻时间短等优点,对儿童患者具有广泛的应用前景。提出了儿童脐血移植的选择策略。     

吻合血管自体腓骨移植修复胫骨缺损

目的:评价应用吻合血管自体腓骨移植修复胫骨缺损的疗效.方法:回顾性分析自1999年8月～2007年10月应用吻合血管腓骨移植修复胫骨缺损16例病例资料,骨缺损长度4.5～12.0 cm,平均7.0 cm.采用自体腓骨5.5～16.0 cm,平均11.0 cm;7例同时行自体髂骨植骨.以外固定架、钢板螺钉或螺钉结合石膏托固定.结果:全部患者获得平均2年11个月(1～8年)的随访,伤口均一期愈合,除1例外,皮瓣均成活,无血管危象发生.X线片示术后4～8个月移植腓骨与受体骨愈合,愈合时间平均6.6个月.患肢开始部分负重时间为术后4～8个月.1例移植骨于术后1年因完全负重而骨折.自体腓骨联合髂骨移植者术后10个月～2年患肢完全负重,单用自体腓骨移植者术后1.5～3年患肢完全负重,均无移植骨骨折.结论:吻合血管自体腓骨移植修复胫骨缺损具有骨愈合可靠、并发症少的优点,联合自体髂骨植骨可促进移植骨增粗塑形,早日恢复负重功能.     

胰岛素疗法对于老年糖尿病患者骨矿含量及骨质疏松发生率的影响

为了探讨胰岛素疗法对于老年糖尿病患者骨矿含量及骨质疏松发生率的影响,我们采用SD-1000型骨矿物仪对使用胰岛素或非胰岛素治疗的50岁以上Ⅱ型糖尿病患者各30例进行了尺桡骨骨矿含量测定,并以相应年龄、性别的健康人100例作对照进行分析讨论,现报告如下。 1 对象与方法 1.1 对象 1.1.1 胰岛素治疗组:包括单独或联合使用胰岛素治疗者。胰岛素剂量为每日12～48U,分次于餐前30min皮下注射,治疗时间为1年以上。本组中男性16例,女性14例;年龄50～78岁,平均62.5岁,病程1～30年,平均8.9年.合并酮症酸中毒3例,糖     

胰岛素依赖型糖尿病胰岛移植15例的临床观察

我院自1983年4月份以来,对15例胰岛素依赖型糖尿病(IDDM)患者施行异体胰岛移植的临床治疗,现作一简要报告。 1.一般资料 15例中男11例、女4例;年龄12～48岁;病程2～15年;其中12例多次发生过严重酮症酸中毒;空腹血糖平均286mg/dl,餐后120分钟平均血糖426mg/dl;平均胰岛素剂量68u/日。     

自体造血干细胞移植治疗恶性血液病

为探讨恶性血液病的有效治疗方法,应用自体骨髓移植(ABMT)38例,自体外周血造血干细胞移植(ABSCT)13例,自体外周血造血干细胞与自体骨髓联合移植15例。治疗白血病54例,恶性淋巴瘤11例,多发性骨髓瘤1例。外周血造血干细胞采用化疗加多抗甲素或C—CSF动员。移植物采用微波、阿克拉霉素净化处理。结果:两组动员方案均有良好动员效果。ABSCT组及联合移植组造血功能恢复比ABMT组快(P<0.05),合并症少。66例中,45例仍呈持续缓解(CCR),中位CCR时间32(5～98)个月,复发21例。3年无病生存率及复发率分别为68.5％及26.1％。结果表明:自体造血干细胞移植是根治恶性血液病的有效手段。ABSCT及联合移植具有造血功能恢复快,合并症少等优点。微波和阿克拉霉素体外净化移植物是一种简便、有效的净化方法。     

人工血管移植治疗腹主动脉瘤17例

腹主动脉瘤 (ＡＡＡ)是腹主动脉局限扩张性疾病。随着病程的进展 ,可出现致命的瘤体破裂。1992～ 1997年 ,我们采用人工血管移植治疗腹主动脉瘤 17例 ,效果较好。1　临床资料1 1　一般情况　本组 17例 ,男 13例 ,女 4例 ;年龄38～ 74岁 ,平均 61岁。合并有高血压病、动脉粥样硬化 12例 ,冠心病 4例 ,胆石症 3例 ,马方综合征、肝血管瘤、大隐静脉曲张、气管炎各 1例 ,有吸烟史11例。1 2　诊断　因发现腹部搏动性肿块就诊 12例 ,其中伴腹痛 10例 ,发现肿块时间 :10ｄ～ 3年 ,平均 4个月。因单纯腹痛就诊 3例 ,疼痛主要位于脐周 ,或腰背部及剑…     

非清髓异基因造血干细胞移植后急性白血病复发5例报告

目的 研究分析非清髓异基因外周造血干细胞移植(NAST)后急性白血病复发的相关因素。方法 29例急性白血病患者NAST后5例复发，男2例，女3例，中位数年龄36岁(18～59岁)。非清髓预处理方案：环磷酰胺、阿糖胞苷及CD3单克隆抗体，3例患者在此基础上加用氟达拉滨。结果 5例均顺利渡过造血抑制期。2例早期形成供者造血细胞完全嵌合体(FDC)并在FDC状态下复发。3例移植早期形成供受者混合造血细胞嵌合体(MC)，2例转为FDC后复发，1例在稳定MC状态下复发。5例中4例复发前无急性或慢性移植物抗宿主疾病(GVHD)，另1例NAST后发生Ⅱ度aGVHD并在皮肤慢性GVHD未治愈状态下复发。5例中1例行2次NAST治疗，在第2次完全缓解，但于2个月后再次复发，放弃治疗。另4例未再继续治疗，2例分别于复发后1和2个月死亡，2例仍带病存活。结论 NAST简便安全，并发症少，白血病复发率无明显升高，为治愈白血病提供了新手段。     

夫妻间肾移植效果分析及其伦理问题探讨

目的 探讨夫妻间肾移植术临床应用可行性.方法 10例夫妻间供肾术前全部进入伦理审批准备过程.供肾均采用全麻;妻子供肾6例,丈夫供肾4例;患者术前HLA配型＞3位点匹配,群体反应性抗体（PRA）＜20%;血型A-A 6例,B-B 2例,O-A或B 2例.根据螺旋CT血管成像或肾动脉造影结果,1例因左肾肾动脉有分支,切取右肾,其余9例均切取左肾.术后免疫抑制方案术中MP 1.0 g,术后第1、2天MP 0.5 g,术后第3天环孢霉素A （CsA）6.0 mg/（kg＆#183;d）,霉酚酸酯（MMF）2.0/d,泼尼松30 mg/d,随访CsA根据谷值浓度调整,6个月时MMF 2.0/d,10 mg/d.结果 全部供体顺利度过围术期,术后8-10 d出院,随访观察6个月以上未发现高血压,肾功能正常,能参加正常工作.全部受体均得到随访,10例移植肾在开放血管后1 min内出尿,其中1例妻子供肾受体术后发生加速性排斥反应（AAR）,经应用OKT3 10 d控制排斥,受体患者复查至2010-01移植肾功能正常.结论 夫妻间肾移植伦理反对和心理拒绝少,治疗效果满意.     

肝移植治疗原发性胆汁性肝硬化

 目的 总结肝移植治疗原发性胆汁性肝硬化(primary biliary cirrhosis,PBC)的效果. 方法 2002-04至2007-04为15例原发性胆汁性肝硬化患者进行了原位肝移植,对其术前状况进行了Mayo评分,并对随访数据进行了分析. 结果 15例入院时平均Mayo评分8.05.均接受了原位肝移植术,术后4例出现共6次急性排斥反应,经过治疗均全部治愈;3例术后新发乙肝,1例新发丙肝;1例顽固性高血糖;1例肝动脉狭窄,经过放置支架后痊愈;1例因胆道弥漫性非吻合口狭窄、肝功能衰竭于术后4个月死亡;1例术后6个月以后失访,失访前状况良好.其余13例平均随访时间47(41~84)个月,目前受者及移植物均存活.围术期生存率100%,排除1人失访,其余14人1年生存率92.9%,3年生存率92.9%.结论 在我国肝移植已经成为治疗终末期PBC的有效方法.PBC术后维持较高的免疫抑制水平是必要的,同时要重视预防术后嗜肝病毒感染.     

Transjugular intrahepatic portosystemic shunt. Experiences at a liver transplantation center

Objective: Transjugular intrahepatic portosystemic shunt (TIPS) placement is an established therapy for portal hypertension that leads to variceal bleeding or refractory ascites. We present experiences of the role of TIPS at a liver transplantation center.Material and Methods: One hundred and ten patients were referred to the Radiological Department for TIPS placement. One of the 110 patients had recurrent cirrhosis after liver transplantation with refractory ascites. Function of the TIPS was controlled with Doppler US at 1 day, 1 week, 4 weeks and 4 months after TIPS placement and subsequently every 3 months. Shunt insufficiency was supposed when the blood flow velocity within the stent tract was under 50 cm/s and was an indication for TIPS revision.Results: TIPS was placed in 101 patients. After TIPS placement, 10 patients underwent liver transplantation. While waiting for the new liver, none of them developed variceal rebleeding, ascites or other complications of portal hypertension. Two of the 101 patients had episodes of rebleeding. The frequency of patients undergoing TIPS revision within the first year after TIPS placement was 67.5%, within the second year 38.0% and within the third year 24.4%. The revisions led to sufficient reduction of the portosystemic pressure gradient.Conclusion: In some liver transplant candidates, TIPS can be useful in minimizing the risk of complications of portal hypertension during the waiting time for a liver transplantation. TIPS can be monitored by Doppler US and revised if occlusion occurs.     

Treatment of Hodgkin's disease with high-dose chemotherapy and autologous stem cell transplantation

High dose chemotherapy (HDC) with autologous stem cell transplantation (SCT) was applied for the treatment of 13 patients (pts) with Hodgkin's disease (HD) (10 with relapsed form and 3 with conventional chemotherapy resistant form) in the Clinic for Hematology, Military Medical Academy, from May 1997 to October 1999. After the initial treatment for the reduction of tumor, burden stem cells were mobilized by cyclophosphamide 2.5-7.0 g/m2 with G-CSF 5-12 micrograms/kg body mass (BM). The average number of colected mobilized mononuclear cells (MNC) was 2.99 (1.66-5.9) x 10(8)/kg BM by the apheresis large volume from peripheral blood. All patients received BEAM (BCNU, etoposide, Cyto-Ara, and melfalan) conditioning regimen with adequate supportive therapy. Good engraftment (100%) was observed at postransplantation period: number of polymorphonuclear cells was > 0.5 x 10(9)/l, on day 13th (10-21) and number of platelets > 20 x 10(9)/l, on day 17th (11-28). One patient (7.6%) died due to infective complications at day 98th after transplantation, 9 (69.2%) patients achieved complete and 3 (23.1%) patients partial remission of the disease. Out of three patients with partial remission, one relapsed, seven months after autologous SCT, with conventional chemotherapy resistant form and two, after the applied conventional locoregional radiotherapy reached remission. One patient (7.6%) developed secondary malignancy of acute myeloid leukemia form with threelinage displasy 27 months after autologous SCT. HDC with autologous SCT contributes to more successful treatment of early relapsed and standard chemotherapy resistant forms of HD and gives the opportunity for successful quality of living for those patients.     

Second allogenic bone marrow transplantation after late graft rejection in a patient with severe aplastic anemia

Allogeneic bone marrow transplantation (BMT) is the treatment of choice in young patients (pts) with severe aplastic anemia (SAA) who have an HLA identical sibling donor. Late graft rejection to following allogeneic BMT for SAA is a significant clinical problem and is associated with a high risk of mortality. The optimal treatment strategy for patients with late graft rejection after first BMT is still an open question. We report 12-year-old patient with acquired SAA who underwent BMT from his HLA identical sister. BMT was first-line treatment within 3 months of diagnosis. Preparative therapy was Cyclophosphamide (Cy) 200 mg/kg body mass (BM) during 4 days. Graft versus host disease (GVHD) was prevented with Methotrexate (MTX), Methylprednisolone (MPDN) and Cyclosporin A (CsA). After 17 months, during which patient was with normal blood counts and full donor chimaerism, graft rejection occurred. The patient was re-engrafted from the same donor after conditioning with Cy 200 mg/kg BM plus horse antithymocyte globulin (ATG)--2 vials (á 25 mg)/10 kg BM over 4 days. Before the collection, donor's bone marrow was activated with low dose rhGM-CSF (3 micrograms/kg one day). Following a secondary BMT engraftment has sustained. The patient is alive with full donor chimaerism 26 months from secondary transplantation, without acute or chronic GVHD.     

DNA profiling in blood, buccal swabs and hair follicles of patients after allogeneic peripheral blood stem cells transplantation

To investigate the possibility that buccal swab and hair follicle samples could be used to detect recipients' personal identification or kinship study in forensic cases, who have received allogeneic peripheral blood stem cells transplantation (allo-PBSCT). Seven casework examples of materials collected from individuals after allo-PBSCT and their donors were investigated. Detection of genotypes was preformed by PCR analysis of short tandem repeats (STRs) in blood, buccal swab and hair follicle samples. Donor genotypes were detected in all blood samples of the patients. Case 2 recipient presented obvious chimeric DNA patterns (54% donor) and case 3 showed almost donor genotype (90% donor) in buccal swab samples. Other cases exhibited much lower chimeric DNA patterns in some alleles (from 2-16% donor). The average time after allo-PBSCT in case 2 and 3 recipients (123 months) was much longer than that of others (11 months). All of 7 recipients did not show donor-derived DNA patterns in hair samples. Therefore, this study suggests that sometimes buccal swab contains DNA from donor and yet hair follicle is a better source of personal identification or kinship study of recipients.     

Results of arthroscopic fixation of osteochondritis dissecans lesion of the knee with cylindrical autogenous osteochondral plugs

BACKGROUND: In situ fixation of unstable lesions of osteochondral dissecans of the knees with cylindrical osteochondral autograft transplantation has been reported to provide excellent results with healing of the osteochondral dissecans fragment. PURPOSE: To evaluate the clinical results and magnetic resonance imaging findings of the osteochondral dissecans of knees treated with in situ fixation of the osteochondral fragments with osteochondral autograft transplantation. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Twelve knees (12 patients; mean age, 16.0 years) with osteochondral dissecans lesions were treated with in situ fixation with autogenous osteochondral plugs. The mean lesion size was 2.4 cm(2) (range, 1.0-4.9 cm(2)). The osteochondral dissecans lesions were located on the medial femoral condyle in 10 patients and on the lateral femoral condyle in 2 patients. Seven lesions were located in the weightbearing area. The International Cartilage Repair Society classification in arthroscopic findings was grade II in 1 patient, grade III in 8 patients, and grade IV in 3 patients. All patients were evaluated with the Hughston Rating Scale form with the mean follow-up at 4.5 years (range, 2.8-5.9 years). The interface between the osteochondral fragment and subchondral bone and changes in donor site of the osteochondral graft were evaluated with T2-weighted magnetic resonance image up to 12 months postoperatively. RESULTS: The Hughston Rating Scale scored 8 knees as excellent, 3 as good, and 1 as fair. The interface between the osteochondral fragment and subchondral bone had disappeared on magnetic resonance image by 3 months postoperatively in all cases. No complications arising from the donor site area were observed. Signal intensity of donor site changed from high signal preoperatively to homogeneous surrounding cancellous bone by 1 year postoperatively. CONCLUSION: Biological fixation of the osteochondral dissecans lesion with cylindrical osteochondral autograft provided healing of the osteochondral fragments.     

心脏死亡器官捐献者供肾移植的可行性

 目的 总结心脏死亡器官捐献(donation after cardiac death, DCD)肾移植的临床资料,并探讨其可行性。方法 回顾性分析2012-04至2013-12武警总医院28例DCD和52例DCD供肾移植的临床资料。结果 28例DCD属于国际标准Maastricht Ⅲ类,共获取肾脏52个并实施肾移植52例。热缺血时间为(11.2±9.1)min,冷缺血时间为(4.1±2.2)h。12例发生移植肾功能延迟恢复(delayed graft function, DGF),发生率23.08%,均于术后20~72 d肾功能恢复正常。急性排斥反应发生率3.85％(2／52),分别于术后1、2周因移植肾破裂切除肾脏。受者死亡3例(术后3个月因巨细胞病毒性肺炎死亡1例,术后移植肾原发无功能并肺部真菌性肺炎1例,肾破裂术后感染性休克1例)。移植肾存活的47例受者,随访13~23个月,移植肾功能正常。结论 DCD 供体可以扩大供体来源,缓解器官短缺困难,但应注意并发症发生,提高移植效果。     

寰枢椎椎弓根钉棒系统内固定治疗牵引复位不稳定型寰枢椎脱位

目的 探讨寰枢椎椎弓根钉棒系统内固定手术治疗牵引复位不稳定型寰枢椎脱位的手术技巧及临床疗效.方法 选择2005年3月-2009年9月收治的寰枢椎脱位患者32例(TOI分型为T2型).其中齿状突骨折19例,新鲜性17例,陈旧性2例;横韧带断裂5例;先天性齿状突发育异常8例.术前日本骨科学会(JOA)评分5～13分,平均8.38分;骨髓有效空间(space available for the cord,SAC)平均9.15 mm.32例患者经颅骨牵引复位后,经颈后路行寰枢椎椎弓根钉棒系统内固定术.结果 32例患者经颅骨牵引后复位,共置入螺钉128枚,手术时间平均1.5 h,出血量平均300 ml,未发生椎动脉及脊髓损伤.全部患者获随访,时间12～24个月,临床症状获得不同程度改善.术后SAC平均14.86 mm;术后1年JOA评分10～17分,平均14.56分,评分改善率为71.70%.X线、螺旋CT复查螺钉位置良好,无钉棒断裂、变形、松动或寰枢椎再次脱位现象.寰枢椎后方植骨于术后3～6个月获骨性融合,1例未植骨,术后1年取出内固定,寰枢关节旋转功能正常.结论 寰枢椎椎弓根钉棒系统内固定技术为寰枢椎提供坚强的三维固定,可直视下置钉,术中复位、融合率高,安全有效,是牵引复位不稳定型寰枢椎脱位的理想治疗方法.

Abstract：

Objective To explore the technique and clinical outcome of the atlantoaxial pedicle screw system in the treatment of the unstable atlantoaxial dislocation post traction.Methods The study involved 32 patients with atlantoaxial dislocation(type T2 of TOI classification)admitted from March 2005 to September 2009.There were 17 patients with fresh odontoid fracture and two with old odontoid fracture,five with traumatic disruption of the transverse atlantal ligament and eight with congenital odontoid dysplasia.JOA scores of neurological function before operation was at a range of 5-13(average 8.38).The average of space available for the cord(SAC)was 9.15 mm.Before the atlantoaxial pedicle screw system was carried out,the skull traction was performed in all the patients preoperatively.Results A total of 128 pedicle screws were inserted safely,with mean operation time and perioperative blood loss for 1.5 hours and 300 ml,respectively.No injury to the vertebral artery or spinal cord was observed.All the patients were followed up for 12-24 months,which showed that JOA scores one year after operation was increased to 10-17(average 14.56),with the improvement rate of 71.70%,and that the SAC was average 14.86 mm.The X-ray and SCT scans verified the proper position of the screws,with no internal fixation failure or atlantoaxial redislocation.After 3-6 months,all the patients except for one patient achieved a solid bone fusion.One year after operation,the one patient with no bone graft fusion was removed of the internal fixation system and obtained satisfactory restoration of the rotational function.Conclusions Atlantoaxial pedicle screw system is an effective method for the treatment of the unstable atlantoaxial dislocation post traction,for it has the advantages of stable three-dimension fixation,direct screw placement,intraoperative reduction and high fusion rate.