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1.
3.0 T MRI不同脉冲序列对胰腺疾病的诊断价值   总被引:2,自引:2,他引:0  
目的 探讨MRI检查不同脉冲序列对胰腺病变的诊断价值。方法 对87例临床怀疑胰腺病变的病人应用3.0 T MR设备进行检查,扫描序列包括双回波T1WI(同相位与反相位成像)、脂肪抑制T1WI(T1WI+FS)、脂肪抑制T2WI (T2WI+FS)、磁共振胆胰管水成像(MRCP)、快速多层面扰相梯度回波(FSPGR)动态增强扫描。由2名放射科医师分析不同脉冲序列的MRI所见。结果 正常胰腺15例,急性胰腺炎27例,慢性胰腺炎30例,胰腺癌15例。T1WI+FS显示胰腺形态与信号最佳,正常胰腺呈稍高信号。在双回波T1WI上,胰腺与周围组织对比度降低。胰腺病变在T1WI上表现为低信号50例,T2WI+FS显示胰周渗出性病变34例。MRCP显示胰管扩张35例,胆管扩张20例,双管征9例。快速扰相梯度回波(FSPGR)动态增强显示胰腺癌13例,肿块在动脉期表现为相对低信号,延迟期轻度强化,周围血管受侵2例。结论 合理应用MR扫描序列有助于提高胰腺病变的诊断效能。  相似文献   

2.
目的 分析颅内和体部血管外皮细胞瘤的MR特征,探讨MR对其的诊断价值. 资料与方法 经手术病理证实的血管外皮细胞瘤9例,术前均经MR检查.MR检查序列包括SE T1WI、FSE T2WI、FSE T2WI脂肪抑制和梯度回复回波(GRE),其中6例行SE T1WI或GRE动态增强扫描.分别确定病变形态、信号特征和强化程度,并与手术病理进行对照. 结果 9例中,位于颅内3例,四肢4例,腹膜后1例,腹股沟1例.病灶多呈不规则分叶状软组织肿块,直径4.8~13.5 cm,平均6.7 cm,其中<5 cm 1例,5~10 cm 7例,>10 cm 1例.9例病灶内可见坏死,6例可见蚯蚓状和结节状血管流空信号.SE T1WI肿瘤实质成分呈低、等或略高信号,所有病例T2WI呈等或略高信号.6例动态增强扫描病例中,动脉期显著强化5例,中等程度强化1例;门脉期均显著强化,强化程度与邻近大血管相仿.颅内、外血管外皮细胞瘤的MR表现无明显区别. 结论 血管外皮细胞瘤呈不规则分叶状软组织肿块,瘤内常见血管流空和坏死,T2WI呈略高信号,动态增强扫描呈进行性延迟强化,强化显著.  相似文献   

3.
目的:探讨MRI多种成像技术对胰腺癌的诊断价值,确定胰腺MRI的最佳扫描组合序列。方法:回顾性分析经手术病理证实的43例胰腺癌的MRI图像,扫描序列包括:平扫FS FLASH T1WI、TSE T2WI、True FISP T2WI、HASTE-MRCP和动态增强3D VIBE序列等。测量正常胰腺与病灶的信号强度,计算胰腺/肿瘤的CNR,对各序列图像质量进行评分。将各序列MRI诊断和评价结果与手术病理对照。结果:胰腺/肿瘤CNR:多时相动态增强3D VIBE序列,以胰腺实质期的胰腺/肿瘤的CNR最高(9.7),其同期所获得的图像质量最优(3.54±0.64),均优于平扫各序列(P<0.05)。对胰腺肿瘤的评价:动态增强3D VIBE序列在检出胰腺癌及评价癌肿胰周血管受累、邻近器官受侵及转移灶方面均为最优(P<0.05);MRCP对胰腺癌导致的胰胆管受侵最敏感,其次是True FISP序列;综合各序列诊断的敏感性和准确性均优于任何单一的平扫、水成像或动态增强扫描序列。结论:胰腺癌的MR检查,多种扫描序列各有优缺点,联合应用能发挥最大潜力。理想的检查组合应包括:平扫屏气FS FLASH T1WIT、SE T2WI、高分辨率的厚层及薄层MRCP、屏气的三维梯度回波序列多时相动态增强扫描。  相似文献   

4.
膝关节软骨缺损性病变的MR成像序列研究   总被引:17,自引:1,他引:16  
目的 评价各种临床常用MR扫描序列诊断关节软骨病变的价值。方法 实验猪膝关节 5只 ,在股骨内外髁关节面软骨上制成缺损模型 ,分别采用各种常用序列扫描 ,测量各种扫描序列上关节软骨的信噪比 (SNR)、软骨相对周围组织的对比噪声比 (CNR) ,采用一致性评价指标 (ICC)评价软骨缺损MRI测量值与实际测量值的一致性。采用实验中优选的MR序列对 2 3例膝关节病变患者进行检查 ,并与关节镜分级诊断结果比较。结果 实验膝关节软骨SNR良好者有质子和T2 WI快速自旋双回波 (FSEPD/T2 WI)、附加脂肪抑制的三维快速扰相梯度回波 (FS 3DFSPGR)和附加脂肪抑制的质子和T2 WI快速自旋双回波 (FSFSEPD/T2 WI)。CNR表现“极佳”者 ,对骨皮质 :FS 3DFSPGR、FSFSEPD/T2 WI;对关节液 :脂肪抑制快速自旋回波 (FSFSE)T2 WI、FS 3DFSPGR ;对半月板和韧带 :FS 3DFSPGR、FSFSEPD/T2 WI、SET1WI、反转时间为 70 0ms的T1WI反转恢复 (IRTI70 0 )序列 ;对脂肪 :FS 3DFSPGR、SET1WI。ICC只有IRTI70 0序列有统计学上的意义 (P <0 .0 5 ) ,且一致性评价为“极佳”。对2 3例膝关节病变患者MR检查结果 :FS 3DFSPGR序列的敏感性为 86 %、特异性为 96 %、表示准确度的Kappa值为 0 .8;IRTI70 0序列的敏感性为 6 8%、特异性为 99%、Kappa值为 0  相似文献   

5.
目的 通过比较不同磁共振(MR)序列对肛瘘病变的显示,总结肛瘘患者的最佳MR序列.方法 41例经手术病理证实为肛瘘患者术前行均行MRI检查.MR扫描序列包括矢状位T2WI(Sag T2WI)、轴位T2脂肪抑制序列(Ax T2 WI-SPAIR)、冠状位T2脂肪抑制序列(Cor T2WI-SPAIR)、轴位弥散加权成像(...  相似文献   

6.
目的:在3.0T磁共振上,分析评价自由呼吸背景抑制弥散序列在胰腺癌中的应用价值。方法:20例正常志愿者行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、弥散加权成像(DWI)及三维LAVE平扫,25例经手术病理证实的胰腺癌患者,术前行常规T1WI、频率饱和脂肪抑制T2WI、MRCP、DWI、三维LAVE及增强三维LAVA扫描,DWI序列基于SE-EPI序列及b值为0和600s/mm2,应用自由呼吸背景抑制技术,统计学比较分析正常胰腺、胰腺癌、邻近胰腺及远端炎症区的ADC值。结果:不同组织的ADC值从低到高依次为胰腺癌、正常胰腺、远端炎症及邻近胰腺组织,单因素方差分析显示不同组织的ADC值有明显统计学差异,F值为17.936,P值为0.0003,两两比较分析显示胰腺癌分别与正常胰腺、邻近胰腺及远端炎症的ADC值统计学有明显差异,P值分别为0.00591、0.000347及0.00211。结论:在3.0T磁共振上,自由呼吸背景抑制DWI序列有助于病灶筛查,其ADC值能够较好的反映胰腺癌、正常胰腺、邻近胰腺及远端炎症的组织病理状态。  相似文献   

7.
胰腺肿瘤Mn-DPDP增强MRI表现   总被引:2,自引:0,他引:2  
目的:描述胰腺肿瘤Mn-DPDP增强MRI表现。资料与方法:27例胰腺肿瘤患者中胰腺癌22例,神经内分泌肿瘤2例,囊腺瘤1例,囊腺癌2例。行SET1W脂肪抑制FSE T2W及脂肪抑制SE T1W和SPGR T1W平扫后,行Gd-DTPA动态增强,次日按0.5ml/kg体重的剂量经肘静脉以2-3ml/min的流率缓慢滴注Mn-DPDP,于给药结束后30min以24h行SE T1W及SPGR T1W扫描。结果:在Mn-DPDP增强后两种序列扫描图像上22例胰腺癌和2例神经内分泌肿瘤均无强化,囊腺癌和囊腺瘤实质部分有不确定轻度强化。结论:Mn-DPDP增强后胰腺癌无强化,神经内分泌肿瘤及囊腺癌或瘤Mn-DPDP增强MRI表现有待于更进一步研究。  相似文献   

8.
慢性胰腺炎与胰腺癌之动态MRI比较   总被引:1,自引:0,他引:1  
为评价快速多平面毁损梯度回波(fast multiplanar spoiled GRE, FMSGRE)MR动态增强技术对慢性胰腺炎性肿大和胰腺癌的鉴别诊断价值,作者收集了1992~1996年间经MR检查并病理证实的31例胰腺占位病变,其中胰腺癌24例,男13例,女11例,年龄52~77岁,慢性胰腺炎性肿大7例,男5例,女2例,年龄46~66岁。另选14例因胰外病变行动态MR扫描患者做正常对照组。采用1.5T磁共振机、FMSGRE序列,TR/TE为100~170ms/1.3~  相似文献   

9.
目的 探讨肝脏、胰腺病变在Mn -DPDP增强MRI检查中的强化特征。方法  2 5例Mn -DPDP增强MRI检查 ,其中有15例先行Gd -DTPA增强扫描。常规扫描序列为SET1WI、FSET2 WI、FSET1WI脂肪抑制序列。Mn -DPDP剂量为 0 .5ml/Kg体重 ,肘静脉缓慢滴注 ( 2~ 3ml/min) ,于给药结束后 40min~ 1h扫描 ,序列为SET1WI和FSPGRT1WI ,5例病人 2 4h后复查。结果 原发型肝癌 10例 ,8例为轻度不均匀强化、2例呈半环状强化。肝硬化 2例 ,表现为结节状均匀一致强化且信号高于正常肝组织。肝血管瘤 2例、肝转移瘤 2例、肝囊肿 1例均无强化 ;胰头癌 8例 ,病灶无强化 ,周围胰腺组织明显强化。结论 Mn -DPDP对比剂能使正常肝脏、胰腺显著强化。该药物峰值持续时间长 ,可提供充裕的扫描时间窗  相似文献   

10.
不同MR扫描序列在SPIO增强大鼠肝癌模型的对比研究   总被引:3,自引:2,他引:1       下载免费PDF全文
目的:比较多种扫描序列超顺磁氧化铁(SPIO)增强扫描对显示大鼠肝癌病灶的能力,找出最佳扫描方案。TSE T2WI、SE双回波的T2WI+PDWI、GRE T1WI、T2^*WI,分析增强前后大鼠肝癌病灶的强化特征,并进行病理学检查对照分析。结果:注射SPIO对比剂后,所有扫描序列均显示肝脏的信号强度较增强前有不同程度的下降,肝癌病灶CNR均分别高于平扫。增强后GRE T2^*WI中病灶的CNR明显高于其它序列,但增强后TSE T2WI和常规SE T2WI在显示病变的SNR、CNR方面没有显著性差异。结论:SPIO增强后检测肝癌病灶的各种序列中,以GRE T2^*WI最为敏感,其次是双回波的T2WI+PDWI序列。  相似文献   

11.
PURPOSE: To determine whether chemical-shift-selective (CSS) fat suppression is necessary for ferumoxide-enhanced T2-weighted fast spin-echo (FSE) imaging in the detection of malignant hepatic tumors. MATERIALS AND METHODS: Ferumoxide-enhanced magnetic resonance (MR) images obtained in 38 patients with surgically confirmed 61 malignant hepatic tumors (36 hepatocellular carcinomas (HCCs), 25 metastases) were retrospectively reviewed by three independent readers. Three sequences of MR images with CSS fat-suppressed T2-weighted FSE, non-fat-suppressed T2-weighted FSE, and T2*-weighted gradient-recalled-echo (GRE) sequences were randomly reviewed on a segment-by-segment basis in a blind fashion. Observer performance was tested using the McNemar's test and receiver-operating-characteristic (ROC) analysis for the clustered data. Lesion-to-liver contrast-to-noise ratio (C/N) was also assessed. RESULTS: The mean C/N with the CSS fat-suppressed FSE sequence was highest in HCCs, metastases, and tumors overall. Sensitivity was highest with the CSS fat-suppressed FSE sequence in HCC, was highest with the non-fat-suppressed FSE sequence in metastases, and was comparable in tumors overall. Specificity was comparable between the sequences. The area under ROC curve (Az) value was greatest with the CSS fat-suppressed FSE sequence in HCCs, was greatest with the non-fat- suppressed FSE sequence in metastases, and was comparable in tumors overall. The sensitivities and Az values were lower with the GRE sequence than the FSE sequence. CONCLUSION: The CSS fat-suppressed FSE sequence was superior to the GRE sequence in the detection of HCCs, but the non-fat-suppressed FSE sequence was comparable to the GRE sequence. The non-fat-suppressed FSE sequence was superior to the CSS fat-suppressed FSE and GRE sequences in the detection of metastases. Optimal FSE imaging with CSS fat suppression or without aiming for the detection of HCCs or metastases, respectively, outperforms GRE imaging in ferumoxide-enhanced MRI.  相似文献   

12.
目的 :分析精囊出血的MR表现 ,提高对精囊出血病变的认识。方法 :对 5例精囊出血的病例分别采用轴位T1WI、T2 WI、T1WI脂肪抑制序列及矢状位T2 WI序列行MR检查 ,并回顾性分析MRI表现。结果 :精囊出血表现为条状、结节状或纡曲短T1、长T2 异常信号 ,T1压脂后病灶显示更清晰并同周围组织区分开来。结论 :各种序列结合使用的MRI是精囊出血的可靠的非创伤性诊断手段。  相似文献   

13.
PURPOSE: To determine the efficacy of three different MR sequences in the evaluation of parametrial invasion by early-stage cervical cancer. MATERIAL AND METHODS: Eighteen consecutive patients with cervical cancer clinically assessed as stage IB1 underwent MR imaging examination with the use of the following sequences: FSE T2-weighted, FSE fat-suppressed T2w, and SE fat-suppressed Gadolinium-enhanced T1w. In all cases, the presence or absence of parametrial invasion on both sides per each sequence used was evaluated. Subsequently all the sequences have been considered together for the evaluation of tumor invasion. Gold standard of the study was the histopathologic analysis of the surgical specimens. RESULTS: At histological examination, parametrial invasion by tumor was found in 6 out of 36 parametria evaluated. The accuracy achieved with each of the sequences used was as follows: 94% with FSE T2w; 86% with FSE fat-suppressed T2w; and 67% with SE fat-suppressed Gadolinium-enhanced T1w. The simultaneous evaluation of all 3 sequences obtained an accuracy level similar to that achieved with FSE T2w. The difference between the accuracy of T2w sequences and that of fat-suppressed contrast-enhanced T1w sequences was statistically significant (p<0.01). DISCUSSION AND CONCLUSIONS: Our data suggest that the MR imaging protocol for the evaluation of parametrial tumor invasion could be restricted to FSE T2w sequences. These proved to have the highest negative predictive value (97%) which allows a reliable selection of patients who can be surgically treated.  相似文献   

14.
RATIONALE AND OBJECTIVES: To compare manganese-DPDP-enhanced and gadolinium-DTPA-enhanced MR imaging in patients suspected of having pancreatic cancer. METHODS: Fifteen patients who underwent MR imaging for suspected pancreatic cancer and received gadolinium-DTPA took part in a clinical phase III trial in which the efficacy of manganese-DPDP for detection of pancreatic cancer was evaluated. T1-weighted gradient-echo (GRE) images with and without fat suppression were used. Signal-to-noise ratio and contrast-to-noise ratio were calculated before and after the administration of each contrast agent. Image quality was assessed using a four-step score; delineation of the normal pancreas was assessed by two readers in consensus. RESULTS: In terms of pancreatic signal-to-noise ratio, only gadolinium-DTPA-enhanced fat-suppressed and non-fat-suppressed GRE imaging showed a significant (P < 0.001) increase (72% and 61%, respectively). In the patients with a focal pancreatic lesion (n = 14), a significant increase in contrast-to-noise ratio was found only in manganese-DPDP-enhanced GRE imaging without (106%) and with (82%) fat saturation. Qualitative image analysis demonstrated a significant improvement of manganese-DPDP-enhanced fat-suppressed MR images in delineating the pancreatic parenchyma (P < 0.01) as well as pancreatic tumors (P < 0.01). CONCLUSIONS: T1-weighted manganese-DPDP-enhanced GRE imaging with fat saturation should be regarded as the most suitable combination for detecting a pancreatic lesion.  相似文献   

15.
Objective. To compare fat-suppressed fast spin-echo (FSE) T2-weighted images with gradient-recalled echo (GRE) T2*-weighted images in the evaluation of anteroinferior labral tears. Design. MR images were retrospectively reviewed by two radiologists masked to the history and arthroscopic findings. They separately interpreted the anteroinferior labrum as torn or intact, first on one pulse sequence and then, 4 weeks later, on the other sequence. The MR interpretations were correlated with the arthroscopic findings. Patients. Nine patients with anteroinferior labral tears, and nine similarly-aged patients with normal, labra were studied. Results and conclusions. Observer 1 had a sensitivity of 0.56 on the GRE images and 0.67 on the FSE images (P>0.5), with a specificity of 1.0 for both sequences. Observer 2 had a sensitivity of 0.78 and a specificity of 0.89 for both sequences. In this small study there is no significant difference between GRE and fat-suppressed FSE images in their ability to diagnose anteroinferior labral tears. When evaluating the labrum with conventional MRI, axial fat-suppressed FSE T2-weighted images can be used in place of GRE images without a loss of accuracy.  相似文献   

16.
OBJECTIVE: To compare MR imaging techniques with differing contrast and spatial resolution for evaluation of complete disruption of the ulnar collateral ligament (UCL) anterior bundle in a cadaveric elbow model. DESIGN: Complete UCL tears were surgically created at the typical location for clinical tears in eight of 28 fresh frozen cadaveric elbow specimens. All specimens underwent 1.5 T MR imaging in the oblique coronal plane, using an extremity coil. The sequences employed were: T1-weighted spin echo (T1 SE), proton density-weighted (PD) fast spin echo (FSE), fat-suppressed T2-weighted FSE (T2 FSE), gradient recalled echo (GRE) with a high matrix, PD FSE with a high matrix (HRPD), and fat suppressed T1-weighted SE with intra-articular gadolinium (MRAr). Two radiologists independently graded the UCL with separate and side-by-side assessments. RESULTS: Sensitivity/specificity pairs were as follows for reader A and reader B, respectively: T1 SE: 0.25/0.95, 0.50/0.95; PD FSE: 0.38/1.00, 0.25/1.00; T2 FSE: 0.50/0.95, 0.63/0.95; GRE: 0.63/0.85, 0.63/0.60; MRAr: 0.88/1.00, 1.00/0.80; HRPD: 0.50/1.00, 0.88/0.80. Kappa statistics for measuring interobserver reliability for each sequence were poor under T1 SE (-0.13) and GRE (0.19), moderate under HRPD (0.41) and T2 FSE (0.44) and good under MRAr (0.62) and PD FSE (0.78). For both readers, the rating for overall image quality was highest for HRPD, and the rating for UCL lesion conspicuity was the highest for MRAr. CONCLUSIONS: Of the MR imaging pulse sequences tested, MRAr showed the greatest ability to identify complete ligamentous injuries with good agreement between readers and had the highest subjective preference for lesion conspicuity. However, HRPD had the least interobserver variability and the highest subjective preference for overall image quality.  相似文献   

17.
OBJECTIVE: To estimate the accuracy, sensitivity, and specificity of 3 ferucarbotran-enhanced magnetic resonance (MR) imaging sequences prospectively for the detection of nontumoral portal perfusion abnormalities. METHODS: Thirty-nine noncirrhotic patients with liver metastases underwent computed tomography during arterial portography (CTAP) and MR imaging comprising T1-weighted gradient recalled echo (GRE), T2-weighted fast spin echo (FSE), and T2*-weighted GRE sequences with and without ferucarbotran. Magnetic resonance images were reviewed by 4 blinded observers for rating based on the confidence scale. The accuracy, sensitivity, and specificity for each sequence were measured by receiver operating characteristic analysis. Contrast-to-noise ratio (CNR) and relative signal-to-noise ratio changes were statistically compared. RESULTS: Thirty-nine nontumoral perfusion defects were observed in 22 patients by CTAP. Receiver operating characteristic analysis showed the accuracy was higher for T2*-weighted GRE (0.884) than for T1-weighted GRE (0.572) and T2-weighted FSE (0.597). T2*-weighted imaging achieved the highest sensitivity (81.4%) and the lowest specificity (86.6%). Postenhanced T2*-weighted imaging achieved the highest CNR (19.3 +/- 9.2). CONCLUSIONS: T2*-weighted imaging was the most accurate and sensitive method for detecting portal perfusion abnormalities compared with T1- or T2-weighted imaging, whereas T1- or T2-weighted imaging is superior in specificity to T2*-weighted imaging during ferucarbotran-enhanced MR imaging.  相似文献   

18.
PURPOSE: To compare the accuracy of four breath-hold magnetic resonance (MR) imaging sequences to establish the most effective superparamagnetic iron oxide (SPIO)-enhanced sequence for detection of colorectal hepatic metastases. MATERIALS AND METHODS: Thirty-one patients with colorectal hepatic metastases underwent T1-weighted gradient-echo (GRE) and T2-weighted fast spin-echo (FSE) MR imaging before and after SPIO enhancement. Four sequences were optimized for lesion detection: T2-weighted FSE, multiecho data image combination (MEDIC), T2-weighted GRE with an 11-msec echo time (TE), and T2-weighted GRE with a 15-msec TE. Images were reviewed independently by three blinded observers. The accuracy of each sequence was measured by using alternative free-response receiver operating characteristic analysis. All results were correlated with findings at surgery, intraoperative ultrasonography, or histopathologic examination. Differences between the mean results of the three observers were measured by using the Student t test. RESULTS: Postcontrast T2-weighted GRE sequences were the most accurate and were significantly superior to postcontrast T2-weighted FSE and unenhanced sequences alone (P <.05). For all lesions that were malignant or smaller than 1 cm, respectively, mean accuracies of postcontrast sequences were 0.082 and 0.64 for T2-weighted FSE, 0.90 and 0.78 for MEDIC, 0.92 and 0.80 for GRE with an 11-msec TE, 0.93 and 0.82 for GRE with a 15-msec TE, and 0.81 and 0.62 for unenhanced sequences. CONCLUSION: Optimized SPIO-enhanced T2-weighted GRE combined with unenhanced T2-weighted FSE MR sequences were the most sensitive. Breath-hold FSE postcontrast sequences offer no improvement in sensitivity compared with unenhanced sequences alone.  相似文献   

19.
PURPOSE: To assess the usefulness of MRI and determine which MR sequence is most effective for diagnosing the mild forms of acute pancreatitis. MATERIALS AND METHODS: Forty subjects (20 normal volunteers and 20 patients with a mild form of acute pancreatitis) underwent MRI with fat-suppressed T1-weighted fast low-angle shot (FLASH), half-Fourier acquisition single-shot turbo spin-echo (HASTE), and TSE short TI inversion recovery (TSE-STIR) sequences. The 20 patients with a mild form of acute pancreatitis underwent multidetector CT (MDCT) and MRI within a 24-hour interval. We qualitatively analyzed all of the images by assessing inflammatory changes in the pancreas and peripancreatic fat. We quantitatively compared differences in pancreas-liver contrast between the control and patient groups for each MR sequence by measuring the signal intensities of the pancreas and liver. RESULTS: TSE-STIR was the best of the four modalities for delineating peripancreatic and pancreatic inflammation (P < 0.01). TSE-STIR depicted definitive peripancreatic and pancreatic inflammation in 18 and 15 patients, respectively. MDCT depicted only three cases of peripancreatic inflammation. TSE-STIR was also produced the best the best quantitative results of the MR sequences (P = 0.09). CONCLUSION: MRI is helpful for diagnosing the mild forms of acute pancreatitis. We recommend the use of TSE-STIR imaging as part of the routine protocol for evaluating pancreatitis.  相似文献   

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