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1.
C. Brochard S. Michalak C. Aubé C. Singeorzan H.-D. Fournier L. Laccourreye P. Calès J. Boursier 《Gastroentérologie clinique et biologique》2010,34(12):716-720
Solitary fibrous tumor (SFT) is a rare neoplasm. Liver parenchyma is a rare location of SFT and, in this case, it usually follows a benign course. We report here the case of a 54-year-old man who presented a large SFT tumor of the right hepatic lobe. The tumor was surgically resected. Local recurrence occurred 6 years later as a 15 cm diameter liver tumor. Histological examination of the resected lesion showed features of an aggressive form of SFT. Two years later, the patient presented with complaints of neck pain and ensuing examinations revealed a tumor of the cranial base. A new surgical resection was performed and histological examination confirmed a metastasis of the SFT. Few weeks later, the patient presented an irreducible psoitis due to an iliac bone metastasis. He died within 1 month. 相似文献
2.
Extrapleural solitary fibrous tumor(SFT) is an uncommon mesenchymal neoplasm,presenting most commonly in the intrathoracic sites but which has been reported at numerous extrathoracic locations. The majority of intra-thoracic SFTs are benign,but 10%-15% behave aggressively. We report a case of primary hepatic SFT with histologically benign and malignant areas. A 65-year-old man underwent an abdominal CT scan following a cerebrovascular accident,which demonstrated a sharply demarcated large liver mass with a heterogenous enhancing area and occupying most of the left lobe of the liver. Histological examination following a hemihepatectomy showed an SFT with morphological patterns ranging from benign to malignant areas,including pleomorphism,increased cellularity,herringbone pattern,necrosis and a raised mitotic count. On review of the literature,only an occasional case report with malignant areas in a hepatic SFT was identified. This case highlights that SFT should be included in the differential diagnosis of a hepatic spindle cell lesion,and that on rare occasions,malignant areas can occur in this already uncommon neoplasm. 相似文献
3.
Hiroki Mori Toru Ikegami Satoru Imura Mitsuo Shimada Yuji Morine Hirofumi Kanemura Yusuke Arakawa Mami Kanamoto Jun Hanaoka Koji Sugimoto Takuya Tokunaga 《Hepatology research》2008,38(5):529-533
A sclerosed hemangioma of the liver is an extremely rare type of benign hepatic tumor. A 77-year-old female was referred to Tokushima University Hospital with fever, abnormal liver function tests and a large liver mass. The tumor, 10 x 5 cm in size and located in segment 5-6 of the liver, was depicted as a low density tumor with enhancement by computed tomography (CT). Magnetic resonance imaging (MRI) showed it to be a tumor with a low signal on T1-weighted and a high signal on T2-weighted images. The patient was negative for hepatitis B surface antigen and hepatitis C antibody. She underwent a right hepatectomy for possible malignant liver tumors, including intrahepatic cholangiocarcinoma or fibrolamellar hepatocellular carcinoma. The following histological examination of the surgical specimen revealed the tumor to be a hepatic sclerosed hemangioma with characteristic dense collagenous tissues. We report here on the case of this unusual tumor and review the relevant literature. 相似文献
4.
Alfredo Guglielmi Matteo Frameglia Paolo Iuzzolino Guido Martignoni Giovanni de Manzoni Ernesto Laterza Gian Franco Veraldi Raffaele Girlanda 《Journal of hepato-biliary-pancreatic sciences》1998,5(2):212-216
We report a new case of solitary fibrous tumor (SFT) of the liver, an extremely rare neoplasm. Including the present case no more than ten cases are reported in the English-language literature. To date there is no definite proof of the origin of this tumor. Both mesothelial and fibroblas-tic genesis has been postulated. The monoclonal antibody CD 34 has recently been used for the characterization of SFT. SFT would appear to be histogenetically related to a CD 34 — positive fibroblastic stem cell. A 61-year-old woman was admitted to our department with epigastric and right hypochondriac pain, weight loss, and hypoglycemia. Ultrasonography and computed tomography demonstrated a large heterogeneous mass in the right hepatic lobe. A right hepatectomy was performed. The tumor weighed 2850 g and microscopic section revealed a peculiar random pattern, the so-called patternless pattern of spindle tumor cells separated by abundant thick collagen bands. The tumor presented a number of highly cellular areas composed of plump spindle cell with hyperchromatic nuclei and rare mitotic figures. Ninety percent of the neoplastic cells displayed strong immunoreactivity for CD 34/My 10. The postoperative course was uneventful and the patient is alive and well without recurrence 6 years after surgery. 相似文献
5.
BACKGROUND: Retroperitoneal lipoma is an extremely rare neoplasm. AIMS: The authors report a case of giant retroperitoneal lipoma in a 32-year-old white female, with a history of pain and an abdominal mass over a 2-year period. Total abdominal ultrasonography and barium enema showed a large mass located in the retroperitoneal space behind the ascending colon. Laparotomy showed a large encapsulated tumor measuring 20 x 13 x 10 cm and weighing 3.400 g. The histological study revealed a benign neoplasm of fatty cells. CONCLUSION: The patient remains well 17 years after surgery, without recurrence of the disease. 相似文献
6.
Solitary fibrous tumor of the liver 总被引:2,自引:0,他引:2
Yuan Ji Jia Fan Yang Xu Jian Zhou Hai-Ying Zeng Yun-Shan Tan Department of Pathology Liver Cancer Institute Zhongshan Hospital Fudan University Shanghai China 《Hepatobiliary & Pancreatic Diseases International》2006,(1)
BACKGROUND: Solitary fibrous tumor of the liver is a rare neoplasm. So far, 23 cases have been described in the English literature. We reported an additional case. METHODS: A 46-year-old woman presented with abdominal mass for 2 weeks. Both abdominal sonography and CT scan showed a solid mass occupying the right lobe of the liver. Right lobectomy was performed and the tumor was resected. RESULTS: Pathological examination showed spindle cell and fibroblast-like cells within the collagenous troma. On immunohistochemical staining, these spindle tumor cells showed diffusely CD34 positive reactivity. The post-operative course was uneventful. The patient recovered smoothly, and was alive half a year without evidence of disease recurrence. CONCLUSIONS: The proper diagnosis was depended on CD34 immunohistochemical study. The number of solitary fibrous tumor of the liver reported to date is too limited to confirm the definite prognosis of the tumor. 相似文献
7.
Solitary Fibrous Tumors (SFT) are rare spindle cell neoplasm that typically originate from the pleura. However, cases of the SFT are described with origin in other organs, including the urinary and genital apparatus. Within the kidney, except from the renal pelvis, only 19 cases of SFT are described and such rarity of localization makes the histogenesis and the prognosis of the tumor rather unknown. We report the case of a 72-year-old lady who attended our Unit for a mass that was clinically palpable at the level of the left hemiabdomen. The tomodensitographic test indicated a 19cm-diameter mass of likely pertinence of the middle bystender of the left kidney. She had undergone left radical nephrectomy. The histological examination highlighted a solitary fibrous tumor (SFT): the presence of hypercellularity, of cellular pleiomorphism and of a high number of mitosis has led to a histological diagnosis of malignancy for the neoplasm analyzed. The SFT are of rare clinical comparison: this does not allow for a deep knowledge of the lesion histogenesis and prognosis; moreover, the clinical behavior should be more precisely defined. 相似文献
8.
Moench C Burck I Bug R Bak YJ Richter B Schroeder R Klarner A Strey CW Vogl T Bechstein W 《Zeitschrift für Gastroenterologie》2008,46(1):54-57
A 22-year-old woman was treated for a hepatic lesion with a high suspicion of a liver adenoma at another hospital. The patient presented with unspecific abdominal pain. Further physical examination was unremarkable. A biopsy of the liver lesion revealed hepatic adenoma. Because of the increasing tumour size over a one-year period the patient was referred to our department for surgical therapy. On MRI scan, the liver mass measured 10 x 9 x 9 cm in the right liver lobe with contact to the right hilum. Because of the histological signs of adenoma a right hepatic lobectomy was performed. Postoperative follow-up was uneventful. The pathological diagnosis of hepatic angiomyolipoma was obtained. Angiomyolipoma of the liver is a rare benign mesenchymal tumour often mimicking other hepatic lesions. Histological features are thick-walled blood vessels, mature fat and smooth muscle in various proportions. The biological behaviour of the tumour is benign, although distant metastases are occasionally possible. Due to the potential for malignant transformation, tumour resection should be performed. 相似文献
9.
Hirofumi Uto Masafumi Shigehira Tetsu Kawano Hidehiro Nagatomo Tadanobu Kuribayashi Shoji Taniguchi Kazumi Koga Naoto Komada Tohru Kitamura Toshihiro Maruyama Hirohito Tsubouchi 《Journal of gastroenterology》1996,31(3):441-445
A 21-year-old man was referred to our hospital because of a liver mass lesion detected by abdominal ultrasonography. He had
received no hormonal treatment. Physical examinations revealed no abnormalities, and laboratory data, including hepatic function
test results, were within normal ranges, with the exception of elevated levels of serum protein induced by vitamin K absence
or antagonist (PIVKA)-II (2.2 AU/ml). Abdominal ultrasonography revealed a hyperechoic mass lesion measuring 10×10 cm, with
hypoechoic areas located in the right posterior segment of the liver. A low-density area and a hypervascular area were detected
in the right posterior segment of the liver by computed tomography and celiac angiography, respectively. As hepatocellular
carcinoma could not be completely excluded, the tumor was resected. The tissue consisted of sheets of tumor cells with eosinophilic
cytoplasm and round nuclei showing a thin trabecular pattern, and these histological findings indicated liver cell adenoma.
After resection of the tumor, serum PIVKA-II returned to the normal level. 相似文献
10.
Korkolis DP Apostolaki K Aggeli C Plataniotis G Gontikakis E Volanaki D Sebastiadou M Dimitroulopoulos D Xinopoulos D Zografos GN Vassilopoulos PP 《World journal of gastroenterology : WJG》2008,14(40):6261-6264
A case of a successfully treated solitary fibrous tumor (SFT) of the liver is reported. An 82-year-old female presented with left upper abdominal discomfort, a firm mass on palpation, and imaging studies revealed a large tumor, 15 cm in diameter, arising from the left lobe of the liver. A formal left hepatectomy was performed. Microscopic evaluation showed spindle and fibroblast-like cells within the collagenous stroma. Immunohistochemistry disclosed diffuse CD34 and positive vimentin, supporting the diagnosis of a benign SFT. The patient remained well 21 months after surgery. SFT of the liver is a very rare neoplasm of mesenchymal origin. In most cases it is a benign lesion, although some may have malignant histological features and recur locally or metastasize. With less than 30 reported cases in the literature, little can be said regarding its natural history or the benefitsof adjuvant radiochemotherapy. Complete surgical resection remains the cornerstone of its treatment. 相似文献
11.
F. Zouaidia A. Jahid H. El ouazzani M. Allala B. El khannoussi L. Laraki M. Chkoff Z. Bernoussi F. Mansouri N. Mahassini 《Journal Africain d'Hépato-Gastroentérologie》2010,4(4):241-245
Inflammatory myofibroblastic tumor (IMT) is a clinical and pathological disease entity, which is an inflammatory lesion with unknown etiology and is classified as intermediate neoplasm in theWorld Health Organization histological typing. It usually originates from the lung, but can also arise in any sites in the body. IMT of the stomach in adults is extremely rare, with unpredictable prognosis. We present a 52-year-old woman with exophytic tumor of the stomach. Physical examination showed mild abdominal tenderness in the hypogastrium, but no palpable abdominal mass. Abdominal CT scan showed a mass of approximately 7 cm, between stomach and liver. The final diagnosis was consistent with the IMT that originated from the gastric wall. The clinical and histopathological features of this rare lesion are described with a review of the previously reported cases. 相似文献
12.
Manuel Jakob Matthias Schneider Ingo Hoeller Urban Laffer Reto Kaderli 《World journal of gastroenterology : WJG》2013,19(21):3354-3357
Solitary fibrous tumors are predominantly benign and are most commonly found in the thoracic cavity and pleura; while reports exist in the literature of malignant solitary fibrous tumors and those located in extrathoracic organs, these cases are considered extremely rare. Herein, a case is reported of a malignant solitary fibrous tumor involving the liver that was diagnosed and treated in a 62-year-old woman. The patient presented with complaints of upper abdominal pain and unintentional weight loss. Computed tomography scan of the abdomen revealed a remarkably large mass, measuring 15 cm × 10 cm × 20 cm, which appeared to be unrelated to any particular organ. The intraoperative finding of a wide communication with the left liver suggested hepatic origin, and served as an indicator for tumor resection via left hemihepatectomy. The diagnosis of solitary fibrous tumor and its malignant nature was confirmed by histological and immunohistochemical examination of the resected tissues. Hepatic solitary fibrous tumor is very rare, and surgery remains the mainstay of treatment. Due to limited reports of such tumors in the literature, little can be said about the benefit of adjuvant therapy and prognosis for the rare cases with malignant histological findings. 相似文献
13.
Masato Hoshino Shintaro Nakajima Yasuro Futagawa Shuichi Fujioka Tomoyoshi Okamoto Katsuhiko Yanaga 《Clinical journal of gastroenterology》2009,2(4):320-324
The case was a 30-year-old woman found to have a 7-cm mass around the pancreatic head during a company health examination.
No abnormal values other than anemia were observed in the physical findings, blood exam, and various tumor markers at the
initial visit. An abdominal computed tomography (CT) revealed a tumor, 6.5 cm in diameter, accompanying a hypervascular cystic
lesion in contact with the dorsolateral side of the descending portion of the duodenum and showed a dense stain in the early
phase. Abdominal magnetic resonance imaging (MRI) demonstrated a lesion of isosignal intensity in a T1-weighted image and
of slightly high signal intensity in a T2-weighted image. Endoscopy identified no mucosal lesion and endoscopic ultrasonography
(EUS) showed an unclear border with the liver. The laparoscopic findings revealed a multilocular, elastic tumor that was prone
to bleeding within the abdominal cavity. The tumor was resected immediately, as it was in contact with multiple organs but
continuous with the Glisson’s capsule in the posterior portion of the liver. The tumor was positive for CD34/Bcl-2 and negative
for S100 protein/c-kit/EMA, therefore a diagnosis of solitary fibrous tumor (SFT) was made. The postoperative course has been
favorable. The patient was discharged on day 10 and her course is currently being monitored on an outpatient basis. SFTs are
relatively uncommon as extrathoracic lesions, and those originating from the liver surface are extremely rare. 相似文献
14.
Barbara Barrettara Gaetano Napoli Angelo Lacitignola Paolo Sardelli 《Journal of thoracic disease》2013,5(4):E179-E180
Solitary fibrous tumor (SFT) of the pleura and the lung is an uncommon spindle cell neoplasm arising from the visceral pleura in the majority of the cases. However there are some extrapleural sites including the lung. Current considerations were raised by a peculiar recent case: an 81-year-old female, no smoker, presented with undefined left thoracic pain. Radiographic findings of a large solid lung mass (10 cm × 9 cm). Computed tomography (CT) confirmed the thoracic mass showing characteristics of a well defined mass with capsule, the position of the mass in proximity of the postero-basal and lateral-basal wall. No secondary lesions were found. Through a left inferior lobectomy and ilo-mediastinal lymph node sampling, the entire mass was resected. Histopathological examination revealed a SFT. In conclusion STF is a rare lesion and this case showed a peculiar extremely large lesion never described before in literature.KEY WORDS : Fibrous, lung, tumor, solitary 相似文献
15.
Hiroto Ishikawa Shinji Uchida Yoshinori Yokokura Yasunori Iwasaki Hiroyuki Horiuchi Mamoru Hiraki Hisafumi Kinoshita Kazuo Shirouzu 《Journal of hepato-biliary-pancreatic sciences》2002,9(6):764-768
We report two cases of a nonparasitic solitary huge liver cyst. The first case, that of a 42‐year‐old woman, was admitted with a chief complaint of upper abdominal pain. Computed tomography (CT) scans revealed a huge cyst, 10 cm in diameter, in segments 4 and 5 of the liver, and spontaneous rupture of the cyst with intracystic hemorrhage. Her general condition was improved by transcatheter arterial embolization (TAE). Percutaneous cystic needle aspiration cytological examination revealed no malignant cells, so she was discharged. After 3 weeks, however, the cyst had increased in size, and simple cystectomy was performed. Histological examination proved the cyst to be benign. The patient in the second case, a 70‐year‐old man, was admitted with epigastric discomfort and obstructive jaundice. CT scans revealed a huge liver cyst, 18 × 15 cm, in the right lobe of the liver, with dilation of the bile duct in the lateral segment. Magnetic resonance cholangiopancreatography showed compression of the left hepatic duct by the cyst and dilation of the bile duct in the lateral segment. Endoscopic retrograde cholangiopancreatography disclosed no communication between the bile duct and the cyst. Percutaneous transhepatic cyst drainage was performed, and minocycline hydrochloride was infused. The cyst was reduced in size, and the reduction has been maintained for 20 months since treatment. 相似文献
16.
Liang Zong Ping Chen Guang-Yao Wang Qun-Shan Zhu 《World journal of gastroenterology : WJG》2012,18(44):6515-6520
Extrathoracic solitary fibrous tumors (SFTs) have been described at almost every anatomic location of human body, but reports of SFT in the abdominal cavity are rare. We herein present a rare case of SFT originating from greater omentum. Computed tomography revealed a 15.8 cm × 21.0 cm solid mass located at superior aspect of stomach. Open laparotomy confirmed its mesenchymal origin. Microscopically, its tissue was composed of non-organized and spindle-shaped cells exhibiting atypical nuclei, which were divided up by branching vessel and collagen bundles. Immunohistochemical staining showed that this tumor was negative for CD117, CD99, CD68, cytokeratin, calretinin, desmin, epithelial membrane antigen, F8 and S-100, but positive for CD34, bcl-2, α-smooth muscle actin and vimentin. The patient presented no evidence of recurrence during follow-up. SFT arising from abdominal cavity can be diagnosed by histological findings and immunohistochemical markers, especially for CD34 and bcl-2 positive cases. 相似文献
17.
Hemangioma is a common benign tumor of the liver that is usually asymptomatic. If >4 cm (giant hemangioma), it could present
symptoms related to bleeding, thrombosis, comsumptive coagulopathy, or adjacent abdominal organ compression. If symptomatic
surgical treatment should be considered, liver resection as well as enucleation are considered. Recurrences after surgical
resection are rare. We herein present a case of woman admitted to the emergency room for acute severe respiratory distress.
She had undergone 2 surgical resections of liver hemangiomas. The respiratory syndrome, as showed by chest x-ray, computed
tomography scan, and nuclear magnetic resonance imaging, was related to a recurrent giant multiple hemangioma, creating a
prominent compression of right lung with left mediastinal shift and left heart dislocation. It resulted in pulmonary parenchymal
compression associated with reduced chest wall compliance and increased pulmonary pressure. The patient was not eligible for
surgical treatment because of the disease extension and her clinical conditions. She died 6 months later from respiratory
insufficiency and hypercapnic coma. 相似文献
18.
Henrik Anttinen Aapo Ahonen Aaro Leinonen Matti Kallioinen Erkki S. Heikkinen 《Journal of internal medicine》1982,211(3):227-232
ABSTRACT. An asymptomatic palpable liver tumor developed in a six-year-old girl seven months after commencement of prophylactic nitrofurantoin therapy for recurrent urinary tract infections. The tumor was examined by 99mTc colloid radionuclide scan, compound ultrasonography and angiography. Ultrasonography demonstrated a large, solid tumor (5times 5x8 cm) in the right lobe of the liver which had an echogenic central core surrounded by an area giving low-amplitude echoes. Angiography disclosed that the tumor was well demarcated and hypervascular, containing large tortuous arteries. The uptake of radionuclide in the tumor was normal. The tumor was resected and the pathological findings were typical for focal nodular hyperplasia (FNH) of the liver. The combination of the findings of these three diagnostic imaging methods is probably specific for uncomplicated FNH, a benign and innocuous tumor of the liver. 相似文献
19.
A Case of Extragenital Choriocarcinoma in the Jejunum 总被引:2,自引:0,他引:2
Naohiko Harada M.D. Tadashi Misawa M.D. Yoshiharu Chijiiwa M.D. Yasuhiro Imazono M.D. Hiroshi Fujishima M.D. Hajime Nawata M.D. 《The American journal of gastroenterology》1991,86(8):1077-1079
A case of extragenital choriocarcinoma which produces human chorionic gonadotropin (HCG) in the small intestine of a 48-yr-old Japanese women is reported. Only seven such cases have been reported. The patient complained of postprandial upper abdominal pain and vomiting of 5 months' duration. Nine years before, right upper lobectomy was performed because of lung undifferentiated carcinoma. Double-contrast examination of the small intestine showed irregular ulceration in the lower jejunum. Celiac angiography demonstrated a hypervascular tumor stain in the branch of the jejunal artery. The serum HCG level was elevated. Gynecological examination revealed nothing abnormal. A small intestinal neoplasm was diagnosed, and a partial resection of the jejunum was performed. Endoscopy on the operating table showed a large, irregularly shaped sessile ulcer. Histologically the tumor was diagnosed as choriocarcinoma, composed of syncytiotrophoblastic cells and cytotrophoblastic cells. Immunohistochemical staining for HCG was positive. No metastasis was present. Although extragenital choriocarcinoma in the small intestine is rare, it should be included in the differential diagnosis of small intestinal neoplasm. 相似文献
20.
Shina Horiuchi Takao Endo Hideki Shimoji Hiroaki Takahashi Masaki Mitsuuchi Atsushi Yawata Hiroaki Mita Mio Yoshida Yoshiaki Arimura Hirofumi Sakamoto Fumio Itoh Yuji Hinoda Kohzoh Imai Kazuaki Sasaki Masaaki Sato 《Journal of gastroenterology》1998,33(4):582-587
We report a case of a 62-year-old woman with goblet cell carcinoid of the appendix. She was admitted to our hospital in September
1994 after the discovery of liver tumors. After admission, a tumor in the right kidney and multiple tumors in the liver were
found. She was diagnosed with renal cell cancer and metastasis to the liver and underwent excision of the kidney and enucleation
of the largest liver tumor. Histological examination revealed that the liver tumor was a metastatic carcinoid tumor. As carcinoid
tumors have frequently been found in the appendix, endoscopic examination was performed and a lesion was found in the appendix
by colonoscopy. As predicted, the biopsy specimen was a carcinoid tumor, and she underwent an appendectomy. Histologically,
the tumor was a goblet cell carcinoid. Goblet cell carcinoid is a rather rare neoplasm that has the histologic features of
both carcinoids and adenocarcinoma. Forty-two cases of goblet cell carcinoid of the appendix have been reported thus far in
Japan. However, few were diagnosed via endoscopic examination before surgical operation. We also carried out an immunohistochemical
study with anti p53 antibody on the goblet cell carcinoid tumor of the appendix. Most tumor cells were strongly positive, while in three benign
carcinoid tumors investigated simultaneously they were negative. These findings suggest that goblet cell carcinoid has an
aggressive phenotype compared with benign carcinoid tumors.
(Received May 9, 1997; accepted Nov. 28, 1997) 相似文献