The incidence of post dural puncture headache in children

One hundred and five children with malignant disease attended for lumbar puncture which was performed under general anaesthesia. A questionnaire was answered over the next three days to determine the incidence of post dural puncture headache. Ninety-seven questionnaires were returned and the results show that no child aged under ten years developed a headache. Of the children aged 10–12 years, two out of seventeen developed a headache (11.8%). In children aged 13–18 years, five out of ten developed a headache (50%).     

Failure of regional blockade for caesarean section

This four-year retrospective study examined the quality of regional blockade for caesarean section. For patients having spinal anaesthesia, data were available on requirement for analgesic supplementation or conversion to general anaesthesia. In those having epidural anaesthesia, data were available only for conversion to general anaesthesia. A total of 1644 patients due to have caesarean section under spinal anaesthesia were studied and of these, 48 (2.9%) required general anaesthesia at some stage. Of the 1610 patients in whom a caesarean section was started under spinal, 12 (0.75%) received general anaesthesia while 175 (10.9%) required some analgesic supplementation. Of the 827 patients in whom epidural analgesia was in progress for labour and a decision was made to proceed to caesarean section, a total of 87 patients (10.5%) needed general anaesthesia. Of those (763) in whom caesarean section was started under epidural, only 17 (2.2%) were given general anaesthesia because of intra-operative pain. Although these results may fall short of best practice, they may enable the anaesthetist to give more accurate information to patients so that better informed consent can be obtained.     

Cranial subdural haematoma after spinal anaesthesia

Intracranial subdural haematoma is an exceptionally rare complicationof spinal anaesthesia. A 20-yr-old male underwent appendicectomyunder partial spinal and subsequent general anaesthesia. A weeklater, he presented with severe headache and vomiting not respondingto bed rest and analgesia. Magnetic resonance imaging showeda small acute subdural haematoma in the right temporo-occipitalregion. The patient improved without surgical decompression.The pathogenesis of headache and subdural haematoma formationafter dural puncture is discussed and the literature brieflyreviewed. Severe and prolonged post-dural puncture headacheshould be regarded as a warning sign of an intracranial complication. Br J Anaesth 2001; 86: 893–5     

Spinal anaesthesia in infants and children

Every anaesthetist who deals with paediatric patients should have the expertise to perform spinal anaesthesia. Often, children undergoing surgery in the lower part of the body have contraindications for general anaesthesia; in these children spinal anaesthesia is a convenient option.The aim of anaesthesia is to provide good operating conditions for the surgeon while avoiding any harmful psychological sequelae for the child. In addition, the anaesthetist's goal is to lessen the physiological stress response to surgery and to prevent post-operative morbidity. In children, spinal anaesthesia produces a dense intra-operative analgesia and, when combined with general anaesthesia, it reduces the requirements for anaesthetic agents and opioids intra-operatively. Spinal anaesthesia allows a fast return to a bright and alert status, and a rapid return of normal appetite. Following spinal anaesthesia, analgesia continues into the early post-operative period, and nausea and vomiting are uncommon. Consequently, ambulation and discharge are not delayed.Some children develop complications following spinal anaesthesia—for example, a post-lumbar puncture headache and transient neurological symptoms. In young children these symptoms may be difficult to perceive if parents are not informed. When long-lasting, these symptoms may surpass the benefits of spinal anaesthesia and should therefore be identified and treated appropriately.     

Spinal anaesthesia for day case surgery.

Postoperative morbidity in fifty day care patients undergoing spinal anaesthesia was evaluated by means of a postoperative questionnaire. Despite the use of a 26G spinal needle in all patients, there was an overall incidence of spinal headache of 18%, which rose to 39% when considering patients under 40 years of age. Several spinal headaches of three to five days' duration were reported. Patients receiving spinal anaesthesia were compared with a smaller group of patients receiving general anaesthesia for similar procedures, and this group showed no evidence of post-operative morbidity after 48 h. In agreement with a previous study, it is concluded that spinal anaesthesia is not a suitable technique for the young day care patient.     

Comparison of 27-gauge (0.41-mm) Whitacre and Quincke spinal needles with respect to post-dural puncture headache and non-dural puncture headache

BACKGROUND: The incidence of headache after spinal anaesthesia has varied greatly between studies. We compared the incidence of postoperative headache in general and postdural puncture headache (PDPH) when using 27-gauge (G) (outer diameter 0.41 mm) Quincke and Whitacre spinal needles in ambulatory surgery performed under spinal anaesthesia. Methods: In a prospective, randomized study, 676 ASA physical status I-II day-case outpatients were given a spinal anaesthetic through either a 27-G (0.41 mm) Quincke or a 27-G (0.41 mm) Whitacre spinal needle. The incidence of any type of postoperative headache was assessed and the type of headache defined using a standardized questionnaire including PDPH criteria. The severity of the headache was defined using a 100-mm visual analogue scale. Results: For the final analysis, 529 patients were available (259 patients in the Quincke group and 270 patients in the Whitacre group). The overall incidence of postoperative headache was 20.0%, but the incidence of true PDPH was very low (1.51%). The incidence of PDPH in the Quincke group was 2.70%, while in the Whitacre group it was only 0.37% (P < 0.05). The overall incidence of non-dural puncture headache was 18.5% and did not differ between the study groups. Conclusions: True PDPH seldom occurs when a 27-G (0.41 mm) spinal needle is used, although postoperatively a non-specific headache is common. Using the 27-G (0.41 mm) Whitacre spinal needle further reduced the incidence of PDPH. Thus, we recommend routine use of the 27-G (0.41 mm) Whitacre spinal needle when performing spinal anaesthesia.     

Postspinal headache. A comparison of the 24G Sprotte syringe and a 29G Quincke needle]

PATIENTS AND METHODS. A randomised study was performed to compare the frequency of postdural puncture headache in 56 patients who underwent spinal anaesthesia for extra-corporeal shockwave lithotripsy using either a Sprotte 24 G (n = 28) or Vygon 29 G or Quincke type needle (n = 28). Frequency of headache was recorded in a similar group of 28 patients who received general anaesthesia. RESULTS. Dural puncture was easier with the Sprotte 24 G cannula than with the less stable Quincke needle, as documented by a significantly shortened time for insertion of the cannula (4.6 +/- 2.6 vs 8.6 +/- 6.3 min, P less than 0.005). The total frequency of post-operative headache was 57% in the Vygon 29 G group and 25% in the Sprotte 24 G group; 21% of patients in the general anaesthesia group complained of headache. Frequency of postdural puncture headache, classified as being posture-related, was 25% in the 29 G Vygon group, compared with 11% in the 24 G Sprotte group (P = 0.148). When only moderate and severe postdural puncture headache was considered, there was a significant difference (25% vs. 4%; P = 0.026) in favour of the Sprotte cannula. DISCUSSION AND CONCLUSIONS. Thus, the 24 G Sprotte needle was at least as effective as the 29 G Vygon needle, and there is a suggestion that the former is more effective in minimising the incidence of moderate or severe postdural puncture headache.     

Postdural puncture headache A comparison between 26- and 29-gauge needles in young patients

The incidence of postdural puncture headache after spinal anaesthesia with two types of 26- and 29-gauge needles was investigated in 149 patients less than 30 years old. Ten patients, (6.7%), six men and four women, developed typical symptoms of postdural puncture headache, while six (4.0%) developed headache of other origin. There were no headaches in the 29-gauge group. Spinal anaesthesia in four patients (8%) was impossible to perform with the 29-gauge needle. By using the latter, spinal anaesthesia can be given to young adults with little risk of postdural puncture headache.     

Thoracic epidural anaesthesia for coronary artery bypass graft surgeryEffects on postoperative complications

We have performed a retrospective analysis of the peri-operative course of 218 consecutive patients who underwent routine coronary artery bypass graft surgery in this institution. All patients received a standardised general anaesthetic using target-controlled infusions of alfentanil and propofol. One hundred patients also received thoracic epidural anaesthesia with bupivacaine and clonidine, started before surgery and continued for 5 days after surgery. The remaining 118 patients received target-controlled infusion of alfentanil for analgesia for the first 24 h after surgery, followed by intravenous patient-controlled morphine analgesia for a further 48 h. Using computerised patient medical records, we analysed the frequency of respiratory, neurological, renal, gastrointestinal, haematological and cardiovascular complications in these two groups. New arrhythmias requiring treatment occurred in 18% of the thoracic epidural anaesthesia group of patients compared with 32% of the general anaesthesia group (p = 0.02). There was also a trend towards a reduced incidence of respiratory complications in the thoracic epidural anaesthesia group. The time to tracheal extubation was decreased in the epidural group, with the tracheas of 21% of the patients being extubated immediately after surgery compared with 2% in the general anaesthesia group (p < 0.001). There were no serious neurological problems resulting from the use of thoracic epidural analgesia.     

Preoperative airway evaluation using multi-slice three-dimensional computed tomography for a patient with severe tracheal stenosis

A 71-yr-old female with a malignant thyroid tumour was to undergothyroidectomy under general anaesthesia. Preoperative chestx-ray and plain computed tomography (CT) showed severe trachealstenosis. Three-dimensional figures of the trachea and a virtualbronchoscopic movie were obtained from multi-slice CT to evaluatethe stenotic region and to simulate fibroscopic tracheal intubation,respectively. After induction of general anaesthesia with propofol,a tracheal tube was successfully passed through the stenoticregion under the guide of a fibroscope as simulated in the virtualmovie. We conclude that multi-slice CT is useful for preoperativeairway evaluation for patients with stenosis and distortionof the trachea.      

Spinal anaesthesia for outpatient surgery

In a prospective study of 51 young male outpatients given spinal anaesthesia through a 25-gauge needle, we found a 37.2% incidence of postdural puncture headache. In addition, 54.9% complained of backache after surgery. Occurrence of headache significantly prolonged the sick-leave from work. General anaesthesia would be preferred by 31.4% of patients for a similar procedure in the future. These patients had a higher incidence of postoperative backache and pain during lumbar puncture. It is concluded that spinal anaesthesia is not a satisfactory technique for outpatient procedures in young men.     

Use of an information leaflet to improve general practitioners' knowledge of post dural puncture headache

BACKGROUND: The number of women receiving neuraxial anaesthesia for labour and delivery is increasing. Women are also being discharged into the community sooner after delivery. Thus, complications arising from neuraxial anaesthesia may present to general practitioners, so it is of vital importance that they are familiar with and can manage potential problems associated with these anaesthetic techniques. METHODS: A questionnaire was sent to 126 local general practitioners to discover their knowledge of the symptoms, diagnosis and treatment of post dural puncture headache in the parturient. An information leaflet was then circulated to all general practitioners in the region, detailing headaches and other potential problems following epidural analgesia for childbirth, and the questionnaire was reissued. RESULTS: The first questionnaire demonstrated that they had poor knowledge of the symptoms, diagnosis and treatment of post dural puncture headache in the parturient. Following the dissemination of the information leaflet, responses to the second questionnaire showed a significant improvement. CONCLUSION: By comparing the two sets of answers, we demonstrated that the leaflet has successfully improved knowledge of post dural puncture headache and other potential sequelae of obstetric epidural analgesia among general practitioners.     

Anaesthesia and septo-optic dysplasia

Septo-optic dysplasia (De Morsier's syndrome) is a common cause of congenital optic nerve hypoplasia. Associated abnormalities such as hypothalamic/pituitary dysfunction, hypotonia or spasticity, may result in affected children presenting for surgical procedures under general anaesthesia. A 3.5-year-old boy with the undiagnosed condition had his Achilles tendons elongated under an uncomplicated general anaesthetic. The postoperative period was complicated by coma and a major convulsive seizure which responded to glucose and steroids. The importance of awareness of this condition in short children with poor visual acuity who require general anaesthesia is stressed, and the presenting features of seven other cases are demonstrated.     

小儿全身麻醉角膜缝线拆除术后肺不张1例

普遍认为感冒是小儿麻醉的禁忌证.然而,如没有明确的实验室检查结果、胸片体征及典型的临床症状,感冒恢复期的患儿实施全身麻醉是安全可行的.报告1例术前无明显临床症状的感冒恢复期小儿患者全身麻醉拔管后发生肺不张的分析、处理及转归.     

Should air-oxygen replace nitrous oxide-oxygen in general anaesthesia?

The use of compressed air-oxygen mixtures to replace nitrous oxide-oxygen in general anaesthesia was investigated in 378 patients. There were neither prolongations of recovery time nor instances of awareness under anaesthesia. The cost of general anaesthesia using compressed air-oxygen was about half that for nitrous oxide-oxygen mixtures.     

Unnecessary emergency caesarean section due to silent CTG during anaesthesia?

We present a case of a probably unnecessary Caesarean sectiondue to misinterpretation of the cardiotocography (CTG) traceduring general anaesthesia. A 27-yr-old patient in her 30thweek of an uneventful, normal first pregnancy presented witha deep venous thrombosis in the pelvic region. She was to undergoan emergency thrombectomy under general anaesthesia. Duringthe operation, the CTG showed a lack of beat-to-beat heart ratevariation (silent pattern CTG) with normal fetal heart rate.This silent CTG pattern was probably a result of the effectof general anaesthesia on the fetus. The CTG pattern was interpretedas indicating fetal distress, and an emergency Caesarean sectionwas performed after the thrombectomy. The infant was apnoeicand had to be resuscitated and admitted to the neonatal intensivecare unit. The pH at delivery was 7.23 and the baby was extubated2 days later. Mother and child recovered without short-termsequelae. In the absence of alternative explanations, reducedfetal beat-to-beat variability with a normal baseline heartrate during general anaesthesia is probably normal. Br J Anaesth 2001; 87: 791–3     

Influence of anaesthesia on defibrillation threshold

Internal cardioverter-defibrillator implantation can be performed under local or general anaesthesia. Whether the technique of general anaesthesia influences the defibrillation threshold remains a matter of debate. We therefore compared, in a prospective, randomised clinical study, the effect of intravenous anaesthesia using propofol with inhalational anaesthesia using isoflurane on the defibrillation threshold in 68 patients scheduled for transvenous single-lead internal cardioverter-defibrillator implantation. Defibrillation threshold was measured at implantation and at device testing 1 week and 1 month after implantation. Patients acted as their own controls. Neither the anaesthetic technique nor the duration of anaesthesia was associated with significant changes in the defibrillation threshold. We conclude that in this group of high-risk patients, both types of anaesthesia are acceptable techniques for internal cardioverter-defibrillator implantation and testing.     

Temporary back and leg pain after bupivacaine and morphine spinal anaesthesia

Transient neurological symptoms have been reported after hyperbaric lidocaine 5% spinal anaesthetics. We report a patient with neurogenic back and leg pain after uncomplicated bupivacaine and morphine spinal anaesthesia. A healthy 39-yr-old woman received 1.6 ml hyperbaric bupivacaine 0.75% and 250 μg morphine intrathecally. Two hours later, the patient experienced discomfort during suturing of the peritoneum and surgery was completed under general anaesthesia. Recovery was uncomplicated until 13 hr after intrathecal injection, when the patient complained of burning pain in her back extending to the front of the abdomen and similar pain in her thighs. Neurological consultation was obtained. Treatment was started with amitriptyline and the symptoms resolved slowly. Complete recovery occurred over three months. Further studies to assess symptoms after spinal anaesthesia are indicated.     

Neurologic sequelae after caesarean section

BACKGROUND: Because pregnancy increases the sensitivity of nervous tissue to local anaesthetics, pregnant patients may be at higher risk of developing neurologic deficits after spinal block than non-pregnant patients. Therefore, we evaluated prospectively the incidence and type of neurologic symptoms after spinal anaesthesia with hyperbaric bupivacaine for caesarean section. METHODS: In this prospective follow-up study we recorded neurologic complications during anaesthesia and postoperatively until discharge from the hospital of 219 patients, who underwent caesarean section under spinal anaesthesia with hyperbaric bupivacaine (5 mg/ml, mean 13 mg). The patients filled in a questionnaire on the first and fifth postoperative days. In the case of complaints typical of neurologic symptoms they were checked first by the anaesthesiologist and, in the case of persistent symptoms, afterwards additionally by a neurologist. RESULTS: Twenty-six of 219 patients were not included in the further evaluation because of incomplete return of their questionnaires. Seventeen mothers (8.8%) complained of transient neurologic symptoms (TNSs), lasting mostly 1-2 days, in the buttocks and/or legs during the first three postoperative days. Eleven patients (5.7%) complained of postdural puncture headache. Two patients (emergency caesarean section because of protracted labour in one and elective caesarean section because of previous caesarean section in the other) complained of persisting pain or sensory abnormalities. Neither of them felt paraesthesia during lumbar puncture. CONCLUSION: Women after caesarean section under a spinal block seem to suffer more often from TNSs than non-pregnant women. The conclusions are, however, uncertain since we had no control group operated on under other than spinal anaesthesia. The persisting neurologic symptoms in two patients might also be due to the obstetric procedure itself. To find out about the validity and possible underlying causes of our results, we need randomised studies with control groups receiving epidural or general anaesthesia.     

Epidural versus general anaesthesia for elective Caesarean section Effect on Apgar score and acid-base status of the newborn

Elective Caesarean section deliveries over a 5-year period were studied to compare the effect of epidural block with general anaesthesia on the condition of the infant at birth. The Apgar score and umbilical arterial acid-base status were used as determinants of the latter. Epidural block was used in 139 (22.8%) mothers while 471 (77.2%) were performed under general anaesthesia. No babies in the epidural group were severely depressed (Apgar less than 4), compared with 6.2% in the general anaesthesia group. Only 4.3% of the epidural sections were moderately depressed (Apgar 4-6), compared with 15.4% of the others. These differences remained highly significant when infants of less than 2500 g were excluded, and when matched groups were compared. Mean umbilical arterial pH was similar within the two groups (pH 7.28), and was not consistent with asphyxia in almost 90% of the depressed infants. The findings suggest that general anaesthesia, rather than asphyxia or aortocaval compression, is responsible for most of the depressed infants born by elective Caesarean section. This may involve over 20% of babies delivered in this manner, so greater use of epidural block for elective Caesarean section is recommended. Further investigations are required to improve results with general anaesthesia.