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A strong promoter of bacteriophage MB78 does not have minus 35 consensus sequence although it has a TGn motif immediately
upstream of minus 10 sequence as well as the AT rich UP element. It is efficiently recognised by the sigma 70 RNA polymerase,
however, a phage-specific factor competes with sigma 70 RNA polymerase for binding to this region, the binding of the factor
being stronger than that of the polymerase. Contrary to the reports in the literature the polymerase appears not to bind to
the UP element whereas the phage-specific factor does. The latter seems to be involved in the regulation of the promoter activity.
This revised version was published online in July 2006 with corrections to the Cover Date. 相似文献
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