高龄慢性硬膜下血肿术后复发的危险因素分析

目的探讨高龄慢性硬膜下血肿(CSDH)钻孔引流术术后血肿复发的潜在危险因素。方法选择中国科学技术大学附属第一医院2015年4月～2017年6月之间接受钻孔引流术治疗的高龄CSDH患者129例,将其分为复发组和未复发组,对各变量进行单因素及Logistic多因素回归分析。结果 129例CSDH患者钻孔术后6个月内共有13例复发(10.08%)。通过单因素及Logistic多因素回归分析显示,患者的血肿类型(混杂密度型)、血肿厚度及糖尿病与CSDH钻孔术后复发有关;而血肿混杂密度型(P=0.019,OR=2.954)和糖尿病(P=0.011,OR=24.580)是CSDH钻孔引流术后复发的独立危险因素。结论混杂密度型血肿和糖尿病是高龄CSDH钻孔引流术术后复发的独立危险因素,可根据患者的具体临床特点提供个体化的治疗及随访方案,尽量提高高龄CSDH患者的生活质量。     

慢性硬膜下血肿钻孔引流术后复发的危险因素

目的 探讨慢性硬膜下血肿（CSDH）钻孔引流术后复发的危险因素。方法 回顾性分析2018年8月至2022年3月钻孔引流术治疗的188例CSDH的临床资料。术后6个月随访判断复发情况,采用多因素logistic回归模型分析术后复发的危险因素。结果 术后6个月,17例复发,复发率为9.04%;171例未复发。多因素logistic回归分析显示,血肿厚度>25 mm、双侧血肿、高密度血肿是CSDH钻孔引流术后复发的独立危险因素（P<0.05）。结论 CSDH钻孔引流术后具有一定的复发率。如果存在血肿厚度>25 mm、双侧血肿、高密度血肿等情况,CSDH病人钻孔引流术后复发的风险明显增高,应采取针对性措施预防复发,并密切随访。     

慢性硬膜下血肿钻孔引流术后复发的危险因素分析

目的探讨慢性硬膜下血肿(chronic subdural hematoma,CSDH)钻孔引流术后复发的危险因素。方法 2015年1月~2016年12月手术治疗的176例CSDH患者,其中复发患者12例。对比两组患者的年龄、血肿的影像学特征、服药情况,术后头颅CT表现等可能的危险因素;并结合有关文献进行分析。结果未复发患者的平均年龄(54.3±19.2)岁,复发患者的平均年龄(73.2±17.4)岁(P=0.01)。37例双侧血肿患者中复发4例(P=0.04)。服用抗凝药物27例患者中,复发4例(P=0.03)。39例术前CT示血肿密度不均一患者中复发9例(P=0.01);术后CT复查脑复张不全患者27例中,有7例复发(P=0.02);15例大量颅内积气患者中复发3例(P=0.04)。117例术中引流管置于血肿腔前部患者中复发5例,49例引流管留置于血肿腔后部患者中复发7例(P=0.008)。结论高龄、双侧血肿、服用抗凝药物、血肿密度不均一、引流管留置于血肿腔后部、术后颅内积气和脑复张欠佳是CSDH患者钻孔引流术后复发的危险因素。     

影响慢性硬膜下血肿钻孔引流术后复发的因素分析

目的探讨影响慢性硬膜下血肿钻孔引流术后复发的相关因素。方法回顾性分析应用钻孔引流术治疗的160例慢性硬膜下血肿患者的临床资料,采用多因素Logistic回归分析影响术后复发的相关因素。结果 160例患者中,术后复发14例(8.75%),复发时间15天~12月。单因素分析显示年龄(P=0.049)、血肿体积(P=0.004)、术前中线移位(P=0.019)及血肿厚度(P=0.024)与术后复发有关。多因素分析显示血肿体积(P=0.008)是影响患者术后复发的独立因素。结论慢性硬膜下血肿钻孔引流术后复发因素有许多,血肿体积可作为评估复发因素的独立指标。     

改良颅骨钻孔引流治疗慢性硬膜下血肿术后肺部感染及预后不良相关因素分析

目的探讨改良颅骨钻孔血肿引流术治疗慢性硬膜下血肿的安全性和有效性,分析术后病人肺部感染及预后不良的相关因素。方法回顾性分析202例采用改良颅骨钻孔引流术治疗慢性硬膜下血肿病人的临床及影像学资料。结果住院期间发生术后并发症17例(8.4%),其中肺部感染12例,尿路感染2例,切口感染2例,急性无症状脑内点状出血1例。入院时GCS评分(15分)是住院期间发生术后肺部感染的危险预测因素(P=0.003,OR=9.368)。术后3个月随访197例(97.5%),预后良好177例(89.8%),预后不良20例(10.2%)。血肿复发6例(3.0%),死亡2例(1.0%)。年龄≥75岁(P=0.007,OR=6.264)及出院时mRS评分≥3分(P0.001,OR=19.029)是病人预后不良的预测因素。结论改良颅骨钻孔引流术是一种安全、有效的慢性硬膜下血肿手术方式。术前病人GCS评分低(15分)是住院期间发生术后肺部感染的危险预测因素。年龄大(≥75岁)及出院时mR S评分高(mRS≥3分)是病人预后不良的预测因素。     

神经内镜辅助下小骨窗开颅术与传统钻孔术治疗慢性硬膜下血肿的临床疗效Meta分析

目的 通过Meta分析评价神经内镜辅助下小骨窗开颅术与传统钻孔术治疗慢性硬膜下血肿(CSDH)的临床疗效。方法 采用计算机检索中国知网、万方数据、维普网、PubMed、EMbase、Cochrane Library等中、英文数据库,时间从建库至2021年11月。选取包含神经内镜辅助下小骨窗开颅术与传统钻孔术治疗CSDH的临床研究,使用RevMan 4.2软件对数据进行Meta分析。结果 共纳入22篇文献,包括400例分隔型CSDH患者和1 369例CSDH患者。Meta分析结果显示,神经内镜辅助下小骨窗开颅术治疗分隔型CSDH的术后复发率低于传统钻孔术(OR=0.17,95%CI:0.08～0.35,P<0.000 01),术后并发症率低于传统钻孔术(OR=0.13,95%CI:0.06～0.28,P<0.000 01)。神经内镜辅助下小骨窗开颅术治疗CSDH的术后复发率低于传统钻孔术(OR=0.16,95%CI:0.10～0.26,P<0.000 01),术后并发症率低于传统钻孔术(OR=0.15,95%CI:0.10～0.23,P<0.000 01)。结论 ...     

额颞顶枕部机化型慢性硬膜下血肿2例临床分析

目的探讨机化型慢性硬膜下血肿(CSDH)的临床特点及治疗方法。方法对2012~2016年我院神经外科收治的2例机化型CSDH患者的临床资料及治疗方法与效果进行分析。结果 2例患者均为中老年男性,有明确头部外伤史,表现为高颅压症和局灶神经功能损害症状。先行钻孔引流术,效果差;改行骨瓣开颅术清除血肿;骨瓣开颅术后1周均血肿复发;再行钻孔引流术,血肿清除,无复发。结论年龄50岁和头部外伤是机化型CSDH的危险因素;骨瓣开颅手术清除机化血肿的效果优于钻孔引流术;机化型CSDH术后易复发。     

阿托伐他汀对慢性硬膜下血肿术后复发率的影响

目的 观察阿托伐他汀治疗慢性硬膜下血肿(CSDH)的临床效果。方法 将2011年5月-2017年4月本院收治的8O例慢性硬膜下血肿患者随机分为对照组和研究组; 对照组患者采用常规钻孔引流术进行治疗,研究组患者在常规钻孔引流术治疗的基础上口服阿托伐他汀治疗; 比较两种方法的疗效和术后CSDH的复发情况。结果 对照组总有效率为95%,研究组总有效率为97.5%,2组比较无明显差异(P>0.05); 对照组为术后复发率15%,研究组为5%,2组比较有显著差异(P<0.05)。结论 阿托伐他汀可以有效降低慢性硬膜下血肿的术后复发率。     

慢性硬膜下血肿硬膜下引流时间与血肿复发的关系

目的 探讨慢性硬膜下血肿（CSDH）硬膜下引流时间与血肿复发的关系。方法 回顾性分析2017年3月至2022年10月单钻孔引流术治疗的114例CSDH的临床资料。根据术后引流时间分为三组：0～8 h组（n=47）、9～16 h组（n=33）、17～24 h组（n=34）。随访90 d,观察术后血肿复发情况。结果 144例中,术后复发20例,死亡4例;其中0～8 h组血肿复发14例（29.79%）,死亡3例（6.38%）;9～16 h组血肿复发4例（12.12%）,无死亡病例;17～24 h组血肿复发2例（5.88%）,死亡1例（2.94%）。0～8 h组血肿复发率显著高于9～16 h组和17～24 h组（P<0.05）,而三组病死率无统计学差异（P>0.05）。多因素logistic回归分析显示,引流时间较短是术后血肿复发的独立危险因素（P<0.05）。结论 CSDH单钻孔引流术后硬膜下引流的早期终止与血肿复发风险增加有关。早期监测术后硬膜下引流时间并预防早期引流终止可能有助于降低血肿复发率。     

慢性硬膜下血肿术后复发因素探讨

我科从1998年1月至2001年12月共收治慢性硬膜下血肿(chronic subdural hematoma, CSDH)82例,多采用经额单处钻孔引流术,术后死亡1例,血肿复发2例,本文就CSDH术后复发原因等问题进行探讨.     

慢性硬膜下血肿的手术治疗（附48例报告）

目的 探讨慢性硬膜下血肿的手术治疗.方法 CSDH患者48例,12例采用钻颅冲洗手术,36例采用钻颅冲洗加引流手术.结果 通过住院天数、术后出血、脑皮层未复张对两组进行比较,两种方法均取得较好的疗效.结论 CSDH患者的手术治疗首选钻颅冲洗引流术,钻孔冲洗亦是一种好方法,手术的关键在于血肿腔彻底的冲洗.     

硬通道微创穿刺与钻孔引流治疗慢性硬膜下血肿的疗效对比观察

目的探讨两种不同手术方式对于慢性硬膜下血肿患者治疗效果的临床差异性。方法将收治的623例慢性硬膜下血肿手术患者的临床资料作回顾性分析及对比研究,其中335例采用YL-1微创穿刺手术,288例采用钻孔引流手术。结果在手术时间、住院时间方面,两种术式有统计学差异(P0.05)。两种手术方式的治愈率、并发症发生率无明显差异(P0.05),穿刺组有1例患者因新鲜出血行骨瓣开颅。结论对于慢性硬膜下血肿患者,钻孔引流术是经典术式,微创穿刺术亦有明确疗效,且操作方法简便、创伤小,住院周期及花费少,在临床应用中可进一步推广。     

Cerebellar haemorrhage after repeated burr hole evacuation for chronic subdural haematoma.

We report a 79-year-old man whose third burr hole craniotomy evacuation for recurrent chronic subdural haematoma (CSDH) was complicated by cerebellar haemorrhage. The patient died 9 days later. Two previously documented cases in which this complication arose after evacuation of extra-axial collections also resulted in death. Remote cerebellar haemorrhage is a rare complication of neurosurgery but is associated with high mortality. This complication should be considered among the differential diagnoses after neurological deterioration following CSDH evacuation.     

神经内窥镜辅助手术治疗慢性硬膜下血肿

目的探讨内窥镜技术在慢性硬膜下血肿(CSDH)手术治疗中的价值。方法 2008年1月~2012年12月,87例CSDH病人随机分为两组;内窥镜下冲洗引流组(n=42)和传统钻孔冲洗引流组(n=45),比较两组手术效果及术后并发症发生率。结果两组病例手术总有效率无显著差异,但两组恢复至Bender 0级的比率分别为80.0%和95.2%(P0.05)。传统手术组血肿复发9例(20.0%),内窥镜组血肿复发2例(5%),两组间术后血肿复发率有显著差异(P0.05)。结论内窥镜下手术治疗CSDH,效果好,降低了术后血肿复发率。     

单孔双管闭式引流治疗慢性硬膜下血肿

目的 探讨单孔双管闭式引流治疗慢性硬膜下血肿(CSDH)的临床治疗效果.方法 慢性硬膜下血肿患者随机按单孔单管额部引流组,单孔单管顶枕部引流组和单孔双管引流组,各选取30 例.分析其临床资料和影像学资料.结果 单孔双管引流组中线恢复好于其它二组(P ＜ 0.01),颅内积气和残留液体量三组比较均有显著差异(P ＜0.0...     

慢性硬膜下血肿钻孔冲洗术后复发因素分析

目的探讨慢性硬膜下血肿钻孔术后复发的临床影响因素。方法回顾我科收治的218例慢性硬膜下钻孔手术病例,收集相关资料,建立EXCEL表格并完成相关分析,找出有统计学意义的影响因素。结果血肿厚度、有无分隔或脑萎缩、术后中线移位程度、手术前后中线变化值、术后积气程度及术后是否放置引流管6种因素是导致复发的原因,具有统计学意义。结论针对慢性硬膜下病人应采用个体化、综合化治疗方案,加强围手术期管理,提高手术疗效。     

The relationship between Glasgow coma/outcome scores and abnormal CT scan findings in chronic subdural hematoma

OBJECTIVES: Chronic subdural hematoma (CSDH) is one of the most frequent types of intracranial hemorrhage. We evaluated the independent association between abnormal CT findings in CSDH and both Glasgow coma score (GCS) on admission as a measure of consciousness and Glasgow outcome score (GOS) at discharge as a measure of outcome. PATIENTS AND METHODS: One hundred and sixteen consecutive patients with CSDH were studied. The variables considered were brain atrophy, hydrocephalus, hematoma location, midline shift, and hematoma density. After univariate analysis and evaluation of the role of age as a confounder in bivariate analysis, variables that had significant association with Glasgow scores were included in the final multivariate model. RESULTS: Brain atrophy was the only variable with significant independent association (p<0.001; OR=77.214; 95% CI=8.336-715.212) with unfavorable outcome as defined by GOS. On the other hand, hydrocephalus (p=0.042; OR=6.503; 95% CI=1.072-39.449) and higher hematoma densities (p=0.027; OR=2.597; 95% CI=1.116-6.024) independently and significantly increased the risk of severe consciousness impairment when the group with GCS>12 was considered as the reference category. CONCLUSION: Brain atrophy independently increases the risk of unfavorable outcome after CSDH. Hydrocephalus and higher hematoma densities independently increase the risk of severe consciousness impairment after CSDH.     

A retrospective analysis of chronic subdural haematoma recurrence rates following burr hole trephination versus minicraniotomy

The aim of this study was to determine the subdural haematoma recurrence rate in patients with symptomatic chronic subdural haematomas (CSDH) treated with either burr hole trephination (BHT) or minicraniotomy (MC) and to determine whether a statistically significant difference exists between the two techniques. A retrospective analysis of all consecutive patients with symptomatic CSDH treated with BHT or MC at the John Hunter Hospital Neurosurgery Department between July 2004 and July 2016 was performed. After inclusion/exclusion criteria were applied, 368 patients with 439 CSDHs were eligible. Baseline demographic data was recorded for all patients. Statistical analysis was performed assessing haematoma recurrence as the primary outcome and mortality as a secondary outcome. Three hundred and sixty eight patients were included in the study, with 225 being treated with MC and 143 with BHT. Baseline demographic data was similar between the two groups. The recurrence rate for patients treated with BHT was 0.13 (95% CI 0.08–0.18), versus 0.18 (95% CI 0.13–0.23) in the MC group. This difference was not statistically significant. Similarly, there was no statistically significant difference in mortality rates between the two groups. The mortality rate in the BHT group was 0.09 (95% CI 0.05–0.14) versus 0.09 (95% CI 0.05–0.13) in the MC group. In our series there was no difference in recurrence rates or mortality rates between the two groups, suggesting MC is an effective alternative to BHT in the management of symptomatic CSDH.     

One vs. Two Burr Hole Craniostomy in Surgical Treatment of Chronic Subdural Hematoma

Objective

Chronic subdural hematoma (CSDH) is one of the most common types of traumatic intracranial hemorrhage, usually occurring in the older patients, with a good surgical prognosis. Burr hole craniostomy is the most frequently used neurosurgical treatment of CSDH. However, there have been only few studies to assess the role of the number of burr holes in respect to recurrence rates. The aim of this study is to compare the postoperative recurrence rates between one and two burr craniostomy with closed-system drainage for CSDH.

Methods

From January 2002 to December 2006, 180 consecutive patients who were treated with burr hole craniostomy with closed-system drainage for the symptomatic CSDH were enrolled. Pre- and post-operative computed tomography (CT) scans and/or magnetic resonance imaging (MRI) were used for radiological evaluation. The number of burr hole was decided by neurosurgeon''s preference and was usually made on the maximum width of hematoma. The patients were followed with clinical symptoms or signs and CT scans. All the drainage catheters were maintained below the head level and removed after CT scans showing satisfactory evacuation. All patients were followed-up for at least 1 month after discharge.

Results

Out of 180 patients, 51 patients were treated with one burr hole, whereas 129 were treated with two burr holes. The overall postoperative recurrence rate was 5.6% (n = 10/180) in our study. One of 51 patients (2.0%) operated on with one burr hole recurred, whereas 9 of 129 patients (7.0%) evacuated by two burr holes recurred. Although the number of burr hole in this study is not statistically associated with postoperative recurrence rate (p > 0.05), CSDH treated with two burr holes showed somewhat higher recurrence rates.

Conclusion

In agreement with previous studies, burr hole craniostomy with closed drainage achieved a good surgical prognosis as a treatment of CSDH in this study. Results of our study indicate that burr hole craniostomy with one burr hole would be sufficient to evacuate CSDH with lower recurrence rate.     

不同方法治疗高血压性基底节中等量出血的疗效对比分析简

探讨高血压性基底节中等量（20～40m1）出血患者不同治疗方法的预后与转归。共226例患者分别接受药物及支持治疗（76例）、钻孔引流术（94例）和小骨窗血肿清除术（56例）,结果显示,治愈和轻残率分别为保守治疗组23例占30．26％、钻孔引流术组50例占53．19％、小骨窗血肿清除术17例占30．36％;中残、重残和死亡为保守组53例占69．74％、钻孔引流术组44例占46．81％、小骨窗血肿清除术组39例占69．64％。提示钻孔引流术治疗高血压性基底节中等量出血患者疗效优于保守治疗和小骨窗血肿清除术,且安全可靠。