不同核心训练运动处方对办公室文员非特异性腰痛的治疗效果

目的 使用2种核心训练运动处方治疗非特异性腰痛患者,探讨不同运动处方的优缺点。方法 选取20名患有非特异性腰痛的办公室文员为研究对象,按随机数字表法分为腹肌训练组、腰肌训练组进行训练,测量训练前、训练后4周、3个月、6个月的腰腹肌厚度、肌力,以及视觉模拟评分法（visual analogue scale,VAS）评分和Oswestry功能障碍指数（Oswestry disability index,ODI）评分;采用重复测量资料的方差分析探讨不同训练运动处方的治疗效果。结果 两组患者治疗后4周、3个月、6个月的VAS评分、ODI评分、屈腹肌力和治疗前比较,均有改善,差异有统计学意义（P <0.05）,腹肌训练组的ODI评分在治疗后6个月的效果优于腰肌训练组（P <0.05）;两组竖脊肌厚度、伸腰肌力均没有随着治疗时间的推移而改善（P> 0.05）;两组在治疗4周和3个月后,两侧腹直肌厚度均有明显改变（P <0.05）,但在两组间差异无统计学意义（P> 0.05）;所有患者右侧腹直肌厚度的均值大于左侧均值（P <0.05）。不同组别与测量时间对以上指标...     

Sarcopenic-obesity and cardiovascular disease risk in the elderly

Objectives  To determine: 1) whether sarcopenic-obesity is a stronger predictor of cardiovascular disease (CVD) than either sarcopenia or obesity alone in the elderly, and 2) whether muscle mass or muscular strength is a stronger marker of CVD risk. Design  Prospective cohort study. Participants  Participants included 3366 community-dwelling older (65 years) men and women who were free of CVD at baseline. Measurements  Waist circumference (WC), bioimpedance analysis, and grip strength were used to measure abdominal obesity, whole-body muscle mass, and muscular strength, respectively. Subjects were classified as normal, sarcopenic, obese, or sarcopenic-obese based on measures of WC and either muscle mass or strength. Participants were followed for 8 years for CVD development and proportional hazard regression models were used to compare risk estimates for CVD in the four groups after adjusting for age, sex, race, income, smoking, alcohol, and cognitive status. Results  Compared with the normal group, CVD risk was not significantly elevated within the obese, sarcopenic, or sarcopenic-obese groups as determined by WC and muscle mass. When determined by WC and muscle strength, CVD risk was not significantly increased in the sarcopenic or obese groups, but was increased by 23% (95% confidence interval: 0.99–1.54, P=0.06) within the sarcopenic-obese group. Conclusion  Sarcopenia and obesity alone were not sufficient to increase CVD risk. Sarcopenic-obesity, based on muscle strength but not muscle mass, was modestly associated with increased CVD risk. These findings imply that strength may be more important than muscle mass for CVD protection in old age.     

吸气肌训练改善肥胖大学生吸气肌力量和运动能力效果分析

  目的  观察8周吸气肌训练对肥胖大学生肺功能、呼吸肌力量、运动能力、身体成分以及脂质代谢的影响,为肥胖患者优化康复方案提供依据。  方法  于2019年8—10月招募58名肥胖大学生随机分为实验组(28名)和对照组(30名)。实验组进行每周3次强度为50%最大吸气压(P_Imax)、共8周的吸气肌训练,对照组接受的训练除强度设定为5%P_Imax外,其他参数与实验组相同。干预前后分别测定肺功能、呼吸肌力量、运动能力、身体成分和血脂等指标。  结果  实验组和对照组训练计划完成率(依从性)分别为98.0%和99.2%。干预过程中无严重不良事件发生。干预后,实验组P_Imax和6 min步行试验(6MWT)距离较干预前增加(t值分别为-7.44,-4.11,P值均 < 0.05),6MWT后的自我疲劳感觉(RPE)和心率下降(t值分别为2.13,2.63,P值均 < 0.05),而肺功能、身体成分和血脂水平的变化无统计学意义(P值均>0.05);对照组上述各指标的变化均无统计学意义(P值均>0.05)。  结论  8周吸气肌训练能够有效改善肥胖大学生吸气肌力量和运动能力,但对呼气肌力量、肺功能、身体成分和血脂水平并无影响。     

用能谱CT的方法评估成年人腹部脂肪分布特点及其影响因素分析

目的:用能谱CT的方法评估成年人腹部脂肪分布的特点,并分析其影响因素。方法:对105例成年人进行身高、体重、腰围、臀围的测量,并用能谱CT扫描评估腹部脂肪分布特点。结果:与非肥胖者相比,肥胖症患者的腹部皮下脂肪、腹腔和肝脏异位脂肪含量均较高（ P<0.05）,而肌肉内脂肪（IMAT）含量并不随BMI而增加;...     

核心力量训练对腹型肥胖中年出租车司机身体形态的干预效果

目的观察8周核心力量训练干预后腹型肥胖中年男性出租车司机身体形态、体成分及腹部脂肪的变化,为探索腹型肥胖人群身体塑形以及降低代谢综合征(MS)发病风险的方法提供参考依据。方法于2017年4月—2018年10月期间在天津市募集40例受试者随机分为研究组和对照组,对两组均进行健康教育,保持日常活动,不限制饮食,对研究组进行核心力量训练,持续8周。干预前后分别测定两组受试者身体形态指标变化。结果研究组共18人完成调查,对照组共17人完成调查。干预后,研究组受试者腰围[(90.44±8.55)cm]、臀围[(100.11±5.21)cm]、腰腹体脂含量[(37.66±3.74)%]、臀部体脂含量[(29.52±3.42)%]及全身体脂含量[(27.07±3.92)%]均低于干预前,且低于对照组,差异均有统计学意义(均P<0.05)。研究组受试者皮下脂肪厚度[(1.67±0.25)cm]和腹内脂肪厚度[(9.12±0.82)cm]均低于干预前,腹直肌肌肉厚度[(1.05±0.09)cm]高于干预前,且腹内脂肪厚度低于对照组,差异均有统计学意义(均P<0.05);对照组受试者腹内脂肪厚...     

Specificity of auto-antibodies in malaria and the role of polyclonal activation

Sera of 173 individuals living in a malaria endemic region in Upper Volta (Donsé village) were screened for the presence of 14 auto-antibodies by the indirect immunofluorescent and/or passive haemagglutination techniques. At least one auto-antibody (AAb) was detected in sera of 72% (124 out of 173) subjects. No differences in the AAb frequency was observed in the sex or age groups. Conversely, a significant relationship between a high frequency of auto-antibodies, high malaria antibody titres and high IgM levels was observed. Antinuclear antibodies (ANA) (87% of total AAb) and particularly those of speckled pattern of fluorescence were by far the most frequently observed. Smooth muscle antibodies (SMA), heart and gastric parietal cell antibodies and thyroglobulin antibodies were found at a normal frequency. This selective increase in the frequency of one AAb (and not of others) cannot, in our opinion, result from a non-specific polyclonal activation. An alternative hypothesis involving both a specific antigenic and a non-specific mitogenic signal is proposed.     

重组人生长激素在外伤性呼吸困难老年病人肠内营养中的应用

目的:研究重组人生长激素(rhGH)对胸部外伤限制性呼吸困难老年病人的应用.方法:选择多发性肋骨骨折(＞3根)病人16例,年龄均＞70岁,随机分为两组,每组8例.治疗组采用肠内营养 GH,其中GH每天12U,共计8天.对照组仅采用肠内营养.治疗前和治疗后第8天,分别测定血清清蛋白、转铁蛋白、前清蛋白浓度和双手握力试验,观察坠积性肺炎的发生情况.结果:治疗组病人第8天的血清清蛋白、转铁蛋白和前清蛋白水平比对照组明显升高(P＜0.01),双手握力试验较治疗前明显提高(P＜0.01);治疗组病人坠积性肺炎的发生率较对照组明显降低(P＜0.05).结论:rhGH 肠内营养支持可以明显改善老年病人蛋白质合成代谢,增加肌肉的收缩力,增强排痰力度,减少了坠积性肺炎的发生率.     

Nutritional, respiratory, and psychological effects of recombinant human growth hormone in patients undergoing abdominal aortic aneurysm repair.

BACKGROUND: Recombinant human growth hormone (rhGH) has been shown to have powerful anabolic effects and to reduce or even prevent nitrogen catabolism in stressed patients. The effects of rhGH on functional parameters are less clearly defined. The aim of this study was to assess the effects of perioperative rhGH on nutritional markers, skeletal muscle function, and psychological well-being in patients undergoing infrarenal, abdominal aortic aneurysm repair. METHODS: Thirty-three patients undergoing elective infrarenal abdominal aortic aneurysm repair were randomized to one of three groups: (1) control (n = 12): placebo for 6 days before and after surgery; (2) preop + postop (n = 10): rhGH (Genotropin; Pharmacia Ltd, Uppsala, Sweden) 0.3 IU/kg/d for 6 days before and after surgery; and (3) postop (n = 11): placebo for 6 days before and rhGH 0.3 IU/kg/d for 6 days after surgery. Patients were assessed on days -7 and -1 before surgery and days 7, 14, and 60 after surgery. RESULTS: Administration of rhGH resulted in increased insulin-like growth factor 1 levels, the increase being significantly more marked in the group given rhGH preoperatively. Preoperative and postoperative rhGH reduced the postoperative decrease in both serum transferrin and grip strength at day 7 by 30% and 70%, respectively. Postoperative respiratory function and arterial oxygenation also were improved, with significant differences in arterial oxygenation between rhGH-treated and untreated groups. No difference in mood was seen between groups after surgery, nor was there any difference between subjective assessment of fatigue scores between groups. CONCLUSIONS: This pilot study indicates that rhGH administered preoperatively has beneficial effects on skeletal muscle and respiratory function and may be more useful than postoperative rhGH administration alone.     

Limited effects of micronutrient supplementation on strength and physical function after abdominal aortic aneurysmectomy

BACKGROUND: Tissue injury following ischemia-reperfusion is mediated in part by free oxygen radicals. We hypothesized that perioperative micronutrient supplementation would augment antioxidant defenses, minimize muscle injury, and minimize postoperative decreases in muscle strength and physical function following abdominal aortic aneurysmectomy. SETTING: A university-affiliated hospital and regional referral center. DESIGN: A randomized, double-blind, placebo-controlled trial of supplementation with beta-carotene, vitamins C and E, zinc, and selenium for a period of 2-3 weeks prior to surgery and 1 week thereafter. STUDY POPULATION: Patients undergoing elective abdominal aortic aneurysmectomy (n=18 per group). PRINCIPAL MEASUREMENTS: Handgrip and other measures of strength and physical function. RESULTS: Handgrip and quadriceps strength decreased following surgery, but not to a significantly different extent in the placebo and supplemented groups. Self-rated physical function decreased following surgery in the placebo group and was preserved in the supplemented group. CONCLUSIONS: Perioperative supplementation with micronutrients with antioxidant properties has limited effects on strength and physical function following major elective surgery.     

硬膜外吗啡PCA用于两种不同方式全子宫切除术的对比研究

目的对比吗啡硬膜外术后镇痛在经腹和经阴道全子宫切除术患者术后镇痛的效果。方法60例ASAI～II级拟行全子宫切除的患者,按随机化的原则分为两组,每组30例,即经阴道全子宫切除术组(VH组)和经腹全子宫切除术组(AH组)均在腰麻硬膜外联合阻滞下完成手术;PCEA药液配制:吗啡10mg+罗哌卡因12.5mg+氟哌利多5mg配制成100ml,在手术结束前15分钟经硬膜外导管给负荷量5ml,手术结束接上镇痛泵,参数设置:背景输注量为1.5ml/h,指令剂量1ml,锁定时间10分钟,若VAS﹤1则背景输注量调整为1.0ml/h,观察并记录1h、4h、8h、12h、24h疼痛评分,镇静评分、血压、心率、血氧饱和度,恶心呕吐、呼吸抑制等并发症。结果VH组VAS评分明显低于AH组(P<0.01);AH组患者VAS>3的次数较多;AH组的吗啡需求量明显大于VH组(P<0.01);但是VH组的呕吐率明显高于AH组(P<0.01);镇静评分VH组高于AH组(P<0.05)。结论对两种全子宫切除手术吗啡硬膜外术后镇痛均能取得很好的镇痛效果,经腹全子宫切除术患者吗啡需求量较大,经阴道全子宫切除术患者尽管吗啡用量小,但恶心呕吐等副作用发生率明显较高,需要进一步研究。     

不同营养方式对呼吸科老年重症患者呼吸肌力及临床预后的影响

目的 比较不同营养方式对呼吸科老年重症患者呼吸肌力和临床结局的影响.方法 采用随机数字表法,将147例呼吸科老年重症患者按入院先后顺序随机分为肠内(EN)肠外(PN)混合营养组,EN组和PN组,每组49例,观察营养支持前后患者能量代谢指标和呼吸肌力的变化情况及短期结局.结果 营养支持后第7天,各组患者的血浆白蛋白(ALB)、血红蛋白(Hb)、肌酐(Cr)水平和氮平衡均较营养支持前明显升高(P均＜0.01),血尿素氮(BUN)水平较营养支持前明显下降(P＜0.01);混合营养组ALB、Hb、Cr和氮平衡升高幅度均明显高于EN组和PN组(P＜0.05或P＜0.01),BUN下降幅度明显高于EN组(P＜0.05).混合营养组(P=0.021)和EN组(P=0.011)的最大吸气压水平明显高于营养支持前,混合营养组的气道阻断压水平明显低于营养支持前(P=0.025).PN组患者感染性并发症及非感染性并发症发生率明显高于EN组 (P=0.002,P=0.017)和混合营养组(P=0.005,P=0.004),EN组患者的胃潴留发生率明显高于PN组(P=0.035).混合营养组患者的脱机时间、呼吸重症监护病房停留时间、住院时间与20 d死亡率均明显小于EN组和PN组(P均＜0.05).结论 EN与PN联用改善呼吸科老年重症患者营养状况和呼吸肌力的效果明显优于单用EN和PN,其短期临床结局也好于单用EN和PN.

Abstract：

Objective To compare the influences of different routes of nutrition on the outcome and respiratory muscle strength of elderly patients in respiratory intensive care unit (RICU). Methods Totally 147 elderly patients in RICU were equally randomized into combined nutrition group ( combinination of parenteral nutrition and enteral nutrition), total enteral nutrition (EN) group, and total parenteral nutrition (PN) group. The changes of energy metabolism, respiratory muscle strength, and short-term outcome were observed or determined.Results Plasma albumin (ALB), hemoglobin (Hb), creatinine (Cr) levels, and nitrogen balance significantly increased in all group 7 days later ( all P ＜ 0. 01 ), while blood urea nitrogen (BUN) significantly decreased ( P ＜0.01 ). The increase of ALB, Hb, Cr levels, and nitrogen balance were significantly more remarkable than that in EN group and PN group (P＜0.05 or P＜0.01). The decrease of BUN level in the combined nutrition group was significantly more remarkable than that in EN group ( P ＜ 0. 05 ). After nutritional support, the maximum inspiratory pressure in the combined nutrition group (P =0. 021 ) and EN group (P = 0. 011 ) became significantly higher, and occlusion pressure at 0.1 second inspiration level in the combined nutrition group became significantly lower ( P =0. 025). The incidences of infectious and non-infectious complications in PN group were significantly higher than those in EN group (P = 0. 002 and 0. 017, respectively) and combined nutrition group ( P = 0. 005 and 0. 004, respectively). Gastric retention was more common in EN group than that in PN group ( P = 0. 035). The weaning time,length of RICU stay, length of hospital stay and 20-day-mortality were significantly decreased in the combined nutrition group than those in the other two groups ( all P ＜ 0. 05 ). Conclusion The effectiveness of the combined application of PN and EN is superior to PN or EN alone in improving nutritional status and respiratory muscle strength as well as in improving the short-term outcome in elderly patients in RICU..     

痉挛型脑瘫患儿用腹肌训练器的研制与应用研究

目的 研制痉挛型脑瘫患儿用腹肌训练器并观察其在临床中的应用效果,将其应用于临床并进行推广。方法 研制脑瘫患儿用腹肌训练器,包括坐垫板、底架和背部训练板3个部分。2018年1月-2019年12月,选取由佳木斯大学附属第三医院确诊的痉挛型双瘫脑瘫患儿40例,年龄3～6岁,随机分为观察组20例和对照组20例,两组均接受常规康复训练,每周5 d、每日1次,观察组利用腹肌训练器进行腹肌训练,观察组和对照组治疗周期均为3个月,分别于治疗前、治疗后采用徒手肌力检查对患儿进行评估。结果 与治疗前相比,两组患儿治疗3个月后,徒手肌力检查结果均有一定提高,差异有统计学意义(t=2.517、7.768、2.179、8.718,P<0.05);治疗后徒手肌力检查得分显示观察组得分显著高于对照组(t=3.454、2.886,P<0.01)。结论 痉挛型脑瘫患儿用腹肌训练器具备操作简单、自主性强、安全有效,能够改善痉挛型双瘫患儿的腹肌力量,提升脑瘫患儿的康复效果。     

硬膜外吗啡PCA用于两种不同方式全子宫切除术的对比研究

目的对比吗啡硬膜外术后镇痛在经腹和经阴道全子宫切除术患者术后镇痛的效果。方法60例ASAⅠ-Ⅱ级拟行全子宫切除的患者,按随机化的原则分为两组,每组30例,即经阴道全子宫切除术组（VH组）和经腹全子宫切除术组（AH组）均在腰麻硬膜外联合阻滞下完成手术;PCEA药液配制：吗啡10mg＋罗哌卡因12．5mg＋氟哌利多5mg配制成100ml,在手术结束前15分钟经硬膜外导管给负荷量5ml,手术结束接上镇痛泵,参数设置：背景输注量为1．5ml／h,指令剂量1ml,锁定时间10分钟,若VAS〈1则背景输注量调整为1．0ml／h,观察并记录1h、4h、8h、12h、24h疼痛评分,镇静评分、血压、心率、血氧饱和度,恶心呕吐、呼吸抑制等并发症。结果VH组VAS评分明显低于AH组（P〈0．01）：AH组患者VAS〉3的次数较多：AH组的吗啡需求量明显大于VH组（P〈0．01）;但是VH组的呕吐率明显高于AH组（P〈0．01）;镇静评分VH组高于AH组（P〈0．05）。结论对两种全子宫切除手术吗啡硬膜外术后镇痛均能取得很好的镇痛效果．经腹全子宫切除术患者吗啡需求量较大．经阴道全子宫切除术患者尽管吗啡用量小,但恶心呕吐等副作用发生率明显较高．需要进一步研究。     

营养性肥胖大鼠循环瘦素水平和性发育相关指标的变化

目的　观察营养性肥胖大鼠血清中瘦素 (leptin)、雌二醇 (E2 )水平和卵巢发育情况。方法　 2 8天雌性SD大鼠 ,按体重排序 ,选取 6 1～ 10 0百分位点大鼠建立营养性肥胖动物模型 ,4 1～ 6 0百分位点为对照组 ,观察其不同发育时期血清中Leptin和E2水平的变化、卵巢的发育情况及下丘脑促性腺激素释放激素(GnRH)的表达。结果　 15周实验结束时 ,肥胖组大鼠体重较正常对照组超重 2 1 4 % ;实验 6周时改喂普通饲料减肥后 ,体重逐渐接近对照组 ;血中E2水平随鼠龄增加而增加 ,且同期肥胖组雌激素水平高于对照组(尚无统计学意义 ) ;肥胖组大鼠血清中leptin水平明显高于对照组和普食减肥组 (P =0 0 0 0 ) ,并与体重和E2有很好的正相关 (r分别为 0 95 8和 0 896 ,P值分别为 0 0 10和 0 0 39)。肥胖组大鼠较对照组和普食组有更多的成熟卵泡和黄体形成 ,但成熟卵泡的形态明显劣于对照组和普食组。肥胖组下丘脑GnRH表达高于对照组和普食减肥组。结论　雌性肥胖大鼠性发育有提前倾向 ;leptin对肥胖和雌性肥胖大鼠性成熟的提前可能有重要相关作用 ,支持leptin通过促进GnRH分泌而促使其性发育提前的假说     

Iron Beats Electricity: Resistance Training but Not Whole-Body Electromyostimulation Improves Cardiometabolic Health in Obese Metabolic Syndrome Patients during Caloric Restriction—A Randomized-Controlled Study

Caloric restriction (CR) and exercise are cornerstones in the treatment of obesity and cardiometabolic disorders. Recently, whole body electromyostimulation (WB-EMS) has emerged as a more time-efficient alternative to traditional resistance training (RT). However, the effects of WB-EMS compared to RT on cardiometabolic health in obese metabolic syndrome (MetS) patients performed during CR are still unclear. In total, 118 obese MetS patients (52.7 ± 11.8 years, BMI: 38.1 ± 6.9 kg/m²) undergoing CR over 12 weeks (aim: −500 kcal deficit/day) were randomly allocated to either WB-EMS, single-set RT (1-RT), 3-set RT (3-RT) or an inactive control group (CON). Primary outcome was MetS severity (MetS z-score). Secondary outcomes were body composition, muscle strength and quality of life (QoL). All groups significantly reduced body weight (~3%) and fat mass (~2.6 kg) but only 1-RT and 3-RT preserved skeletal muscle mass (SMM). All exercise groups increased muscle strength in major muscle groups (20–103%). However, only the two RT-groups improved MetS z-score (1-RT: −1.34, p = 0.003; 3-RT: −2.06, p < 0.001) and QoL (1-RT: +6%, p = 0.027; 3-RT: +12%, p < 0.001), while WB-EMS and CON had no impact on these outcomes. We conclude that traditional RT has superior effects on cardiometabolic health, SMM and QoL in obese MetS patients undergoing CR than WB-EMS.     

面罩间歇负压辅助通气对COPD呼吸肌疲劳的治疗作用

目的　探索经面罩间歇负压通气对慢性阻塞性肺部疾病呼吸肌疲劳的治疗作用。方法　对慢性阻塞性肺部疾病 (COPD)患者进行面罩间歇负压通气 ,利用微型负压调节泵使呼气相负压值为 - 5cmH2 O ,每天通气 1h ,连续应用 7d ,观察患者的肺功能、动脉血气、呼吸肌肌力改变。结果　与对照组相比 ,治疗组COPD患者的MEP、FEV1.0 、FEV1.0 %、MVV、PaCO2 均有显著性改善 (P <0 .0 5 )。结论　面罩间歇负压通气对慢性阻塞性肺部疾病呼吸肌疲劳有较为肯定的治疗作用     

Relationship between psychosocial factors and objective physical function in special needs school staff members suffering from low back pain

Physical function impairment in patients with low back pain (LBP) occurs due to the influence of psychosocial factors. Only a few studies have objectively evaluated physical function. We aimed to objectively assess the physical functions of individuals subjects with LBP, and clarify the association between physical function and psychosocial factors. We enrolled 411 individuals with LBP working in special needs schools. We examined their degree of pain, and the psychosocial factors strength through the STarT Back Tool, which categorized them into the low-risk, medium-risk, and high-risk groups. We assessed their abdominal muscle endurance, lower limb muscle strength, and hip joint flexibility. The relationships between these physical functions and psychosocial factors were analyzed by logistic regression models. Those in the high-risk group had significantly lower abdominal muscle and lower limb muscle strength (p<0.001). After adjusting for confounding factors, the odds ratios of the high-risk compared to the low-risk group for low abdominal muscle endurance, lower limb muscle strength, and restricted right and left Straight Leg Raising were 5.47, 3.14, 2.65, and 3.12, respectively (95% CIs: 2.35–12.74, 1.43–6.89, 1.08–6.55, and 1.20–8.11, respectively). Therefore, the low physical function observed in the high-risk group was associated with their psychosocial factors.     

中老年女性盆腔器官脱垂盆底肌力特征分析

目的分析中老年女性盆腔器官脱垂(POP)患者盆底肌力、肌电值及疲劳度变化特征。方法选择2019年1-10月沈阳市妇婴医院收治的中老年POP患者70例作为观察组,另选同时期于我院就诊的其他无盆底功能障碍的妇科良性疾病患者70例作为对照组。比较两组患者的盆底肌力(收缩力和阴道横截面肌力)和电生理指标(Ⅰ类和Ⅱ类肌纤维的肌力、肌电值和疲劳度)。结果观察组盆底肌力和阴道横截面肌力均低于对照组,组间差异有统计学意义(P<0.05)。观察组Ⅰ类和Ⅱ类肌纤维肌力和肌电值均低于对照组,组间差异有统计学意义(P<0.05);观察组Ⅰ类和Ⅱ类肌纤维疲劳度均高于对照组,组间差异有统计学意义(P<0.05).结论中老年POP患者盆底支持力明显低于其他妇科良性疾病患者,这不仅表现在盆底肌力方面,即便在Ⅰ类和Ⅱ类肌纤维的电生理指标方面也有所体现。     

Kinesiological examinations and cutaneous EMG with integrated 3D UH system in adolescent idiopathic scoliosis (type: King 1-13)

The origin of idiopathic scoliosis is unknown however there are many hypothesis. One of them is the biomechanic theory. The cause of spreading the cutaneous EMG is: noninvasive, and can be used during movements. AIM: Authors find by CMS system in their earlier examination, that range of right rotation (of idiopathic scoliotic spine King 1-3 type) increased. They supposed that the change of spine motion cause change in muscle functions also. To verify this hypothesis above: they made examinations by cutaneous EMG parallel to the kinesiological examinations.(CMS system, 3D ultrasound movement analyse). METHOD: Kinesiological examinations on 25 girls with idiopathic scoliosis (King 1-3) were performed parallel to examining cutaneous bilateral EMG on eight spinal close muscles. RESULT AND CONCLUSION: They established that beside functional movements there were a so called non-functional movement however this component were small. Analysing the results, they used phase and amplitude analysis. In the course of phase- and amplitude analysis, they took only those changes into consideration which were significantly different of the two side compared with to healty groups. In the course of phase- and amplitude analysis, they found: that muscle erector spine was weakened in strength and decreased in movement range. They intend to make clear the etiology part in idiopathic scoliosis.     

Insulin levels, physical activity, and urinary catecholamine excretion of obese and non-obese rhesus monkeys

The hypothesis that spontaneous obesity in rhesus monkeys is associated with abnormalities in energy expenditure was tested. Obese (n=7) and non-obese (n=5) monkeys were described in terms of body size and composition, food intake, and physical activity. Additionally, the relationships among fasting and stimulated insulin levels in serum, C-peptide levels in serum and urine, and urinary catecholamines were examined. Obese animals had primarily abdominal deposition of excess body fat, as indicated by markedly elevated abdominal circumferences and skin-fold thicknesses. Food intake did not differ between groups. Physical activity was much lower in the obese group. Obese monkeys had markedly higher serum insulin and C-peptide levels in the fasted state and in response to an intravenous glucose challenge. Urinary excretion of C-peptide and catecholamines was measured during successive 2-day periods of ad libitum feeding, food deprivation, and refeeding in order to examine potential differences between groups in sympathoadrenal activity and their relationship to insulin secretion. C-peptide excretion was greater for obese and decreased for both groups during food deprivation. Urinary dopamine (DA), norepinephrine (NE), and epinephrine (E) levels were significantly greater for obese animals in all conditions. DA excretion was lowest during deprivation and E excretion was lowest during refeeding, whereas NE excretion was relatively unaffected by feeding condition. The overall patterns of C-peptide and catecholamine excretion were qualitatively similar for both groups, and there were no reliable differences between obese and non-obese in their responses to the feeding manipulation. The results suggest that hyperinsulinemia associated with obesity in rhesus monkeys is linked to increased catecholamine secretion and a resistance to catecholaminergic action.