K562,K562/ADM的放射敏感性

Ｋ_（５６２），Ｋ_（５６２）／ＡＤＭ的放射敏感性沈世人，邹长，苏颖，高频肿瘤患者在化疗过程中，常产生用药性，但耐药患者肿瘤细胞的放射敏感性是否也相应的发生变化，目前有关报道不多。我们利用本室建立的Ｋ。。：／ＡＤＭ＄药细胞株（ｌ），测定其耐药与非耐药细...     

精神分裂症患者IgG,IgA,IgM及C_3,C_4含量分析

目的　探讨体液免疫异常在精神分裂症发病过程中的作用。方法　利用速率散射比浊法测定 2 5例首发精神分裂症患者、30例经抗精神病药物治疗患者血清中IgG ,IgA ,IgM及补体C3,C4 含量 ,并与正常人作对照分析。结果　未治疗组血清中IgG ,IgA含量显著高于正常人及治疗组 (P <0 .0 1) ,而IgM则无显著性差异 (P >0 .0 5 ) ,治疗组及未治疗组血清C3 含量显著低于正常对照组 (P <0 .0 1)。结论　精神分裂症存在一定程度的体液免疫异常 ,在其发病机理上起到一定的直接或间接作用。     

精神分裂症患者Ig/C_3双特异性循环免疫复合物的检测及意义

目的探讨精神分裂症患者Ig/C3-TCIC水平及临床意义。方法应用捕捉法ELISA,检测65例精神分裂症患者及60例正常对照者血清Ig/C3-TCIC水平。结果精神分裂症患者血清IgG/C3-TCIC含量2.909±0.803,阳性率67.69%;IgM/C3-TCIC含量1.424±0.292,阳性率24.62%;IgA/C3-TCIC含量2.104±0.549,阳性率19.46%,均明显高于正常对照组（P〈0.01）。结论 Ig/C3-TCIC是精神分裂症免疫性脑损伤的重要介质,可作为评价患者免疫状态的重要参考指标。     

CO2激光手术治疗肛裂680例

肛裂是常见的、多发的肛肠疾病,其发生多由于解剖、感染、机械性损伤和内括约肌痉挛等因素造成肛管皮肤损伤。临床表现为大便干躁,便时或便后肛门出血,括约肌痉挛性疼痛,患者十分痛苦。我科采用CO2激光器治疗680例肛裂患者,现将方法与     

89SrCl2在治疗乳腺癌骨转移中的临床疗效

目的 评价⁸⁹SrCl₂治疗乳腺癌骨转移的临床疗效,及其血液学毒副作用。方法 51例患者接受⁸⁹SrCl₂治疗,静脉注射剂量为2.22 MBq/kg体重,观察治疗前后止痛效果,病灶变化和外周血细胞变化。结果 患者疼痛完全缓解率为37.7%(17/45),总缓解率为84.4%。病灶治疗有效率为62.7%(32/51)。治疗后1个月白细胞和血小板减少者分别为76.5%和62.7%。3个月后大多数患者经治疗血象恢复到正常。结论 ⁸⁹SrCl₂可安全、有效地治疗乳腺癌骨转移患者的疼痛,并对其生活质量有所改善。     

超脉冲CO2激光治疗尖锐湿疣合并包皮过长65例临床观察

目的:探讨CO2激光治疗尖锐湿疣合并包皮过长患者的疗效。方法:尖锐湿疣合并包皮过长患者65例,应用超脉冲CO2激光切除过长包皮。结果:65例中,58例患者未发生并发症,伤口愈合良好,术后阴茎外形美观。3例术后发生出血。1例包皮切除过多。2例包皮切除过少。1例术后7d部分切口裂开。结论:将CO激光切除过长包皮的方法用于治疗尖锐     

30例T2N0M0期非小细胞肺癌立体定向放射治疗临床疗效分析

目的 探讨利用体部立体定向放射治疗（SBRT）技术治疗T₂N₀M₀期非小细胞肺癌（NSCLC）的临床疗效及不良反应。方法 回顾性分析接受SBRT治疗的30例不适合手术T₂N₀M₀期NSCLC患者的临床资料,探讨其总生存率、无进展生存率、肿瘤特异性生存率和不良反应。结果 中位随访时间18.4个月。1、2、3年的总生存率分别为92.2%、92.2%和80.6%,肿瘤特异性生存率分别为95.7%、95.7%和83.7%,无进展生存率分别为70.2%、54.1%和40.6%,局部控制率分别为100%、94.4%和94.4%,区域控制率分别为84.2%、72.1%和54.1%,远处控制率分别为84.6%、72.4%和64.3%。20例患者出现1级放疗相关不良反应;5例患者出现≥2级的放射性肺炎;1例患者出现4级放射性肺炎。结论 SBRT治疗对不适合手术的T₂N₀M₀期NSCLC患者有较好的疗效,不良反应可耐受。     

CO2激光治疗脐部肠系膜导管息肉10例

脐部肠系膜导管息肉(umbilical omphalomesenteric ductpolyp)临床上常通俗地称为脐茸或脐息肉(umbilical polyp)。在临床较为少见,多见于婴幼儿。近三年我科收治来自儿科,皮肤科多例脐部赘生物患者,均采用激光治疗。部分行     

精神分裂症患者中透明隔腔的脑CT表现及其临床意义分析

目的：探讨精神分裂症患者中透明隔腔的脑CT表现及其临床意义。方法通过对2006年3月至2013年1月在我院进行治疗的220例精神疾病患者,按照患者病情进行划分,其中精神分裂症患者121例,其他精神疾病患者99例,比较同期的健康者为对照组。观察比较上述检查对象的脑CT表现。结果精神分裂症组透明隔腔检出率为9.9％,其他精神疾病组透明隔腔检出率为1．0％,对照组的透明隔腔检出率为0,精神分裂症组透明隔腔检出率较其他精神疾病组和对照组明显增加（P＜0．05）;精神分裂症组12例透明隔腔患者中,男性患者数为9例,女性患者数3例,男性患者较女性患者数明显增加（P＜0．05）,其中30岁以下青壮年患者数较其他年龄段检出率明显增加（P＜0．05）。结论精神分裂症患者透明隔腔的检出率较其他精神疾病患者和健康者明显提高,证实透明隔腔是为诱发精神分裂症的主要原因。透明隔腔的脑CT在精神分裂症患者检查中有着十分重要的意义,临床值得推广应用。     

Optimization of the system of medical service of students of Cadet Schools of the Ministry of Defense of the Russian Federation

One of the factors of the successful military career guidance Cadet schools students is preserving and promoting their health. Medical support of children and adolescents aged 10-17 years should include the full range of medical and preventive measures defined for this group. The state of providing outpatient care for pupils at the Cadet School in St. Petersburg was studied. These results show that full medical care in accordance with the standards can be based only on children's health clinics. It is important that the organization of medical support pupils cadet schools should be cooperate with civilian health care.     

带状疱疹83例误诊原因分析

带状疱疹是由水痘—带状疱疾病毒引起的皮肤科常见疾病。其主要的病理损害,一是受累神经的严重炎症性浸润,继而导致受侵犯神经节内神经细胞变性、坏死;二是皮肤的水泡。迅速抑制神经节和相应的感觉神经纤维的充血、水肿和坏死,防止粘连形成,达到迅速镇痛、改善皮损,缩短病程及防止后遗症的发生是治疗的关键。因而,尽早明确诊断,     

Estimation of accumulated dose of radiation by method of ESR-spectrometry of dental enamel of mammals

ESR-spectrometry was used to investigate radiation-induced paramagnetic centers in enamel of mammals: carnivores (polar bear and fox), ungulates (reindeer, European bison, moose), and man. Values at half the microwave power saturation of the radiation signal, P_1/2, evaluated at room temperature, was found to range from 16 to 26 mW for animals and man. A new approach to discrimination of the radiation induced signal from the total ESR spectrum of reindeer enamel is proposed. ‘Dose-response’ dependencies of enamel of different species mammals were measured within the dose range from 0.48 up to 10.08 Gy. Estimations of ‘radiosensitivity’ enamel of carnivores and ungulates showed good agreement with radiosensitivity enamel of man by ESR method.     

Analysis of the results of the international comparison of activity measurements of a solution of Fe

The results of an international comparison of activity measurements of a solution of ⁵⁵Fe organized by the BIPM in 2005 are reported and analysed. This exercise, which follows the procedures of the CIPM mutual recognition arrangement to update older comparisons, is a renewal of the comparison organized by the BIPM that took place in 1978. A EUROMET comparison was organized in 1996 specifically to compare activity measurements of a ⁵⁵Fe solution by means of liquid-scintillation techniques. Results of these three comparisons are presented and discussed in this paper.

The radionuclide solution was provided by the NPL, which also distributed the samples to the participants. The activity of the ampoules was measured by 16 laboratories using 12 methods producing 25 results. Some general considerations on uncertainty assessments pertaining to the different techniques used are drawn. The outcome of four different estimators is compared from which the presence of at least one outlier can be confirmed. Further measurements should be made to try to reduce the discrepancy between the results. To date the outcome of the present comparison does not show an improvement to that of the 1996 comparison.     

Evaluation of the results of various technics of non-surgical therapy of varicocele

A new method of non-surgical treatment of varicocele syndrome is described: it consists in sclerotherapy of spermatic vein by trans-femoral percutaneous catheterization with balloon-catheters. In 8 cases venous thrombosis has been induced by direct electric clotting. The techniques and a 6 months follow-up are discussed. It is pointed out that this procedure should be considered as the method of choice for tubular lesions and sub-fertility prophylaxis in young people and in childhood.     

延迟性脾破裂误漏诊原因分析

目的探讨延迟性脾破裂误漏诊原因和预防措施.方法回顾性分析总结12例延迟性脾破裂中的诊断和误漏诊的经验与教训.结果本组延迟性脾破裂的误漏诊5例(41.66%).对多发伤与脾破裂并存可能认识不足,外伤史轻微或伤员隐瞒外伤史,缺乏腹痛-缓解-突然再腹痛的典型病史,缺乏“对冲性脾破裂”力学分析和整体化诊断思路等为其误漏诊的主要原因.结论详细的外伤史和全面系统检查,重视腹以外多发伤掩盖腹内脏器伤及延迟性脾破裂可能.确立外伤-腹内脏器伤-脾破裂整体化诊断思路.不间断地辅以B超检查脾形态学变化和腹内有无积液,腹腔穿刺确定有无血腹、X线胸腹部检查观察左侧胸肋角和膈肌运动情况、必要时CT检查以尽早发现脾包膜下血肿,降低延迟性脾破裂误漏诊率.