四环素着色牙脱色治疗的效果分析

四环素着色牙脱色治疗的效果分析张洪亮１陈杰２李上农３曲燕玲４田青４１９９２～１９９５年，我们应用美国产Ｏｐａｌｅｓｃｅｎｃｅ脱色药治疗四环素着色牙病人５００例，疗效满意，现报道如下。１临床资料１．１一般资料５００例病人中，男７８例，女４２２例；年龄１...     

Electrophoresis of creatine kinase isoforms: a highly sensitive fluorescence scanning method

ＯｂｊｅｃｔｉｖｅＴｏｄｅｖｅｌｏｐａｎａｇａｒｏｓｅｅｌｅｃｔｒｏｐｈｏｒｅｔｉｃｍｅｔｈｏｄｆｏｒｃｒｅａｔｉｎｅｋｉｎａｓｅ（ＣＫ）ｉｓｏｆｏｒｍｓ,ｕｓｉｎｇｈｉｇｈｌｙｓｅｎｓｉｔｉｖｅｆｌｕｏｒｅｓｃｅｎｃｅｓｃａｎｎｉｎｇ．Ｍｅｔｈｏｄ...     

Inhibition of mesangial cell proliferation by antisense oligodeoxynucleotide targeting preproendothelin-1 mRNA in vitro

Ｏｂｊｅｃｔｉｖｅ　Ｔｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｆｅｃｔｓｏｆｅｎｄｏｔｈｅｌｉｎ１（ＥＴ１）ｏｎｍｅｓａｎｇｉａｌｃｅｌｌｐｒｏｌｉｆｅｒａｔｉｏｎｉｎｖｉｔｒｏＭｅｔｈｏｄｓ　Ａｎｔｉｓｅｎｓｅｏｌｉｇｏｄｅｏｘｙｎｕｃｌｅｏｔｉｄｅ（ＡｓＯＤＮ）ａｎｄｉｔｓｃｏｎｔｒｏｌｓｅｑｕｅｎｃｅｓ,ｓｅｎｓｅ（ＳｅＯＤＮ）ａｎｄｍｉｓｍａｔｃｈ（ＭｉｓＯＤＮ）ｏｌｉｇｏｄｅｏｘｙｎｕｃｌｅｏｔｉｄｅｓ,ｔａｒｇｅｔｉｎｇｐｒｅｐｒｏｅｎｄｏｔｈｅｌｉｎ１（ｐｐＥＴ１）ｍＲＮ…     

Endotoxic Damage to the Stria Vascularis： The Pathogenesis of Sensorineural Hearing Loss Secondary to Otitis Media

ＥｎｄｏｔｏｘｉｃＤａｍａｇｅｔｏｔｈｅＳｔｒｉａＶａｓｃｕｌａｒｉｓ：ＴｈｅＰａｔｈｏｇｅｎｅｓｉｓｏｆＳｅｎｓｏｒｉｎｅｕｒａｌＨｅａｒｉｎｇ　ＬｏｓｓＳｅｃｏｎｄａｒｙｔｏＯｔｉｔｉｓ　ＭｅｄｉａＧｕｏＹａｎｇｃｈｕｎ（郭养淳）；ＷｕＹｉｑｉｎ...     

Quantitative in vitro assessment of drug phototoxicity by a chemiluminescence method

ＯｂｊｅｃｔｉｖｅＴｏｅｓｔａｂｌｉｓｈａｔｅｓｔｍｏｄｅｌｆｏｒｐｈｏｔｏｔｏｘｉｃａｇｅｎｔｓｕｓｉｎｇｔｈｅｍｅｔｈｏｄｏｆｃｈｅｍｉｌｕｍｉｎｅｓｃｅｎｃｅＭｅｔｈｏｄｓＴｈｅｐｈｏｔｏｔｏｘｉｃｉｔｙｏｆｐｉｐｅｍｉｄｉｃａｃｉｄ,ｄｏｘ...     

STUDY ON THE INHIBITORY EFFECT OF ANTISENSE ETAR OLIGODEOXYNUCLEOTIDES ON THE PROLIFERATION OF VASCULAR SMOOTH CELLS

Ｒ啨ｓｕｍ啨　　 Ｏｂｊｅｃｔｉｆ　Ｐｏｕｒ啨ｔｕｄｉｅｒｌ ｅｆｆｅｔｉｎｈｉｂｉｔｅｕｒｄｅｓｏｌｉｇｏｄ啨ｓｏｘｙｎｕｃｌ啨ｏｔｉｄｅｓｄｅｃｏｎｔｒｅｓｅｎｓｄｅｓｒ啨ｃｅｐｔｅｕｒｓｄ ｅｎｄｏｔｈ啨ｌｉｎｅＡ (ＯＮＤｓ ＲＥＴＡ)ｓｕｒｌａｐｒｏｌｉｆ啨ｒａｔｉｏｎｄｅｓｃｅｌｌｕｌｅｓｄｅｓｍｕｓｃｌｅｓｌｉｓｓｅｓｖａｓｃｕｌａｉｒｅｓ (ＣＭ ＬＶ) .　Ｍ啨ｔｈｏｄｅｓ　ＬｅｓＯＮＤｓ ＲＥＴＡ ｄｅｓｅｎｓ ,ｄｅｃｏｎｔｒｅｓｅｎｓｅｔｎｏｎａｐｐａｒｉ啨ｓｏｎｔ啨ｔ啨ｓｙｎｔｈ啨ｔｉ…     

Antisense oligodeoxynucleotide inhibits expression of recombinant porcine follicle-stimulating hormone receptor

Ｓｙｎｔｈｅｔｉｃｏｌｉｇｏｄｅｏｘｙｎｕｃｌｅｏｔｉｄｅｓ（ＯＤＮｓ）ｒｅｐｒｅｓｅｎｔａｎｅｗｔｏｏｌｆｏｒｔｈｅｄｉｓｃｏｖｅｒｙｏｆｐｈｙｓｉｏｌｏｇｉｃａｌｍｅｃｈａｎｉｓｍｓｉｎｃｅｌｌｃｕｌｔｕｒｅｓ,ｉｎｔｉｓｓｕｅｓａｎｄｉｎｖｉｖｏ．Ｉｄｅａｌｌｙ,ａｎａｎｔｉｓｅｎｓｅＯＤＮｉｓｔａｒｇｅｔｅｄｉｎａｓｅｑｕｅｎｃｅ－ｓｐｅｃｉｆｉｃｍａｎ－ｎｅｒｔｏｎｕｃｌｅｉｃａｃｉｄｓ（ＲＮＡｏｒＤＮＡ）ｔｏｏｆｆｅｒｔｈｅｅｘｃｉｔｉｎｇｐｏｓｓｉｂｉｌｉｔｙｏｆｓｅｌｅｃｔｉｖｅ…     

Studies of needling depth in acupuncture treatment.

ＳｔｕｄｉｅｓｏｆｎｅｅｄｌｉｎｇｄｅｐｔｈｉｎａｃｕｐｕｎｃｔｕｒｅｔｒｅａｔｍｅｎｔＪａｕｎｇ－ＧｅｎｇＬｉｎ林昭庚ＯｂｊｅｃｔｉｖｅＴｏｉｎｖｅｓｔｉｇａｔｅｓａｆｅｔｙａｎｄＤｅ－ｑｉ（ｏｂｔａｉｎ－ｉｎｇｏｆｎｅｅｄｌｉｎｇｓｅｎｓａｔｉｏ...     

Effect of tripterin on concentration of free calcium and hydrogen in vascular smooth muscle cells

Ｏｂｊｅｃｔｉｖｅ：Ｔｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｆｅｃｔｓｏｆｔｒｉｐｔｅｒｉｎｅｏｎｆｒｅｅｃａｌｃｉｕｍ（Ｃａ2 ）ａｎｄｈｙｄｒｏｇｅｎ（Ｈ ）ｃｏｎｃｅｎｔｒａｔｉｏｎｉｎｖａｓｃｕｌａｒｓｍｏｏｔｈｍｕｓｃｌｅｃｅｌｌｓ（ＶＳＭＣ）．Ｍｅｔｈｏｄｓ：Ｂｙｕｓｉｎｇｆｌｕｏｒｅｓｃｅｎｃｅｓｔａｉｎｉｎｇｍｅｔｈｏｄ,ｃｈａｎｇｅｓｏｆＣａ2 ａｎｄＨ ｉｎｓｉｎｇｌｅＶＳＭＣｗｅｒｅｓｔｕｄｉｅｄａｆｔｅｒｄｉｆｆｅｒｅｎｔｃｏｎｃｅｎｔｒａｔｉｏｎｓｏｆｆｅｔａｌｃａｌｆｓｅｒｕｍ…     

Immunofluorescence study of type Ⅳ collagen α chains in epidermal base-ment membrane : application in diagnosis of X-linked Alport syndrome

ＩｍｍｕｎｏｆｌｕｏｒｅｓｃｅｎｃｅｓｔｕｄｙｏｆｔｙｐｅⅣｃｏｌａｇｅｎαｃｈａｉｎｓｉｎｅｐｉｄｅｒｍａｌｂａｓｅ┐ｍｅｎｔｍｅｍｂｒａｎｅ：ａｐｐｌｉｃａｔｉｏｎｉｎｄｉａｇｎｏｓｉｓｏｆＸ┐ｌｉｎｋｅｄＡｌｐｏｒｔｓｙｎｄｒｏｍｅＤｉｎｇＪｉ...     

Effect of integrin on procollagen synthesis by fibroblasts from scleroderma.

Ｏｂｊｅｃｔｉｖｅ　Ｔｏｉｎｖｅｓｔｉｇａｔｅｔｈｅｅｆｆｅｃｔｏｆｉｎｔｅｇｒｉｎｏｎｆｉｂｒｏｂｌａｓｔｓｆｒｏｍｓｃｌｅｒｏｄｅｒｍａｉｎｔｈｅｐｒｏｄｕｃｔｉｏｎｏｆｐｒｏｃｏｌｌａｇｅｎ－Ｍｅｔｈｏｄｓ　Ｐｈｏｓｐｈｏｒｏｔｈｉｏａｔｅｍｏｄｉｆｉｅｄａｎｔｉｓｅｎｓｅｏｌｉｇｏｎｕｃｌｅｏｔｉｄｅｓｗｅｒｅｕｓｅｄｔｏｉｎｔｅｒｆｅｒｅｗｉｔｈｔｈｅｅｘｐｒｅｓｓｉｏｎｏｆｉｎｔｅｇｒｉｎα５ｏｒβ１ｓｕｂｕｎｉｔｏｎｆｉｂｒｏｂｌａｓｔｓｆｒｏｍ１０ｃａｓｅｓｏｆｓｃｌｅｒｏｄｅｒ…     

Subclasses of warm autoantibody IgG in patients with autoimmune hemolytic anemia and their clinical implications

Ｏｂｊｅｃｔｉｖｅ　Ｔｏｅｘｐｌｏｒｅｔｈｅｍｅｃｈａｎｉｓｍｏｆａｕｔｏｉｍｍｕｎｅｈｅｍｏｌｙｓｉｓａｎｄｅｓｔａｂｌｉｓｈａｍｏｒｅｓｅｎｓｉｔｉｖｅｔｅｓｔｆｏｒａｕｔｏｉｍｍｕｎｅｈｅｍｏｌｙｔｉｃａｎｅｍｉａ（ＡＩＨＡ）Ｍｅｔｈｏｄｓ　ＩｇＧｓｕｂｃｌａｓｓｅｓｗｅｒｅｔｅｓｔｅｄｉｎ４０ｐａｔｉｅｎｔｓｗｉｔｈｉｄｉｏｐａｔｈｉｃｏｒｓｅｃｏｎｄａｒｙＡＩＨＡｂｙＣｏｏｍｂｓｔｅｓｔｗｉｔｈｍｏｎｏｃｌｏｎａｌａｎｔｉｂｏｄｉｅｓＨｂ,ＴＢｉｌ,ＲＣａｎｄＦＨｂ,ａｓｈｅｍｏｌ…     

Fluorescence spectra of human arteries usingXe－lamp as an excitation light source

ＦｌｕｏｒｅｓｃｅｎｃｅｓｐｅｃｔｒａｏｆｈｕｍａｎａｒｔｅｒｉｅｓｕｓｉｎｇＸｅ－ｌａｍｐａｓａｎｅｘｃｉｔａｔｉｏｎｌｉｇｈｔｓｏｕｒｃｅＬｕＥｒｂｉｎ，ＧｕＣｈｕｎｍｉｎｇ，ＷａｎｇＬｉｎｇｙａｎ，ＭａＪｕｎｚｈｉ（ＴｈｅＴｈｉｒｄＣｌｉｎｉｃ...     

Acute Inhalation Toxicity Study of 2-Fluoroaceta mide in Rats

ＮＴＲＯＤＵＣＴＩＯＮＯｎｅｏｆｔｈｅｍｏｓｔｐｏｔｅｎｔｒｏｄｅｎｔｉｃｉｄｅｓｉｓ2＿Ｆｌｕｏｒｏａｃｅｔａｍｉｄｅ(Ｋｌａａｓｓｅｎ,1980).Ｉｔｉｓａｎ“ｕｎｃｌａｓｓｉｆｉｅｄｒｏｄｅｎｔｉｃｉｄｅ”(ｓｔａｔｕｓＩＳＯ765)ａｎｄｌｉｓｔｅｄｕｎｄｅｒＳｃｈｅｄｕｌｅ1ｏｆＰｏｉｓｏｎｓｉｎＵＳＡ.Ｓｉｎｃｅ2＿ｆｌｕｏｒｏａｃｅｔａｍｉｄｅ(2＿ＦＡ)ａｎｄｓｏｄｉｕｍｆｌｕｏｒｏａｃｅｔａｔｅａｒｅｈｉｇｈｌｙｔｏｘｉｃｔｏｏｔｈｅｒａｎｉｍａｌｓ,ｔｈｅｉｒｕｓｅｉｓｒｅｓｔｒｉｃｔｅｄｔｏ…     

Activation of p38 mitogen-activated protein kinase by oxidized LDL in vascular smooth muscle cells: mediation via pertussis toxin-sensitive G proteins and association with oxidized LDL-Induced cytotoxicity

Ｏｘｉｄｉｚｅｄ ｌｏｗ －ｄｅｎｓｉｔｙ ｌｉｐｏｐｒｏｔｅｉｎｓ （ｏｘＬＤＬ） ｈａｖｅ ｂｅｅｎ ｓｈｏｗ ｎ ｔｏ ｐｌａｙ ａ ｃｒｕｃｉａｌｒｏｌｅ ｉｎ ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ, ｂｕｔｔｈｅ ｕｎｄｅｒｌｙｉｎｇｍ ｏｌｅｃｕｌａｒｍ ｅｃｈａｎｉｓｍ ｓ ｈａｖｅ ｎｏｔｂｅｅｎ ｆｕｌｌｙ ｕｎｄｅｒｓｔｏｏｄ． Ｔｈｅ ｐｒｅｓｅｎｔｓｔｕｄｙ ｓｈｏｗ ｅｄ ｔｈａｔｏｘＬＤＬｓｔｒｏｎｇｌｙ ｅｖｏｋｅｄ ｐｈｏｓｐｈｏｒｙｌａ－ｔｉｏｎ ａｎｄ ａｃｔｉｖａｔｉｏｎ ｏｆｐ３８ ｍ ｉｔｏｇｅｎ－ａｃｔｉｖａｔｅｄ ｐｒｏｔｅｉｎ ｋｉｎａｓｅ （ＭＡＰＫ） ｉｎ ｒａｔｖａｓｃｕｌａｒ ｓｍ ｏｏｔｈ ｍ ｕｓｃｌｅ ｃｅｌｌｓ （ＶＳＭＣｓ） ｉｎ ｃｏｎｃｅｎ－ｔｒａｔｉｏｎ－ａｎｄ ｔｉｍ ｅ－ｄｅｐｅｎｄｅｎｔｍ ａｎｎｅｒｓ, ｒｅａｃｈｉｎｇ ｔｈｅ ｍ ａｘｉｍ ａｌａｃｔｉｖａｔｉｏｎ ａｔ１００ μｇ／ｍ ｌｗｉｔｈｉｎ ５ ｍ ｉｎｕｔｅｓ． Ｔｈｅ ｒｅｓｕｌｔｓ ｆｒｏｍ ｉｍ －ｍ ｕｎｏｆｌｕｏｒｅｓｃｅｎｃｅ ｓｔａｉｎｉｎｇ ａｌｓｏ ｒｅｖｅａｌｅｄ ｔｈａｔｐ３８ ＭＡＰＫ ｗ ａｓ ａｃｔｉｖａｔｅｄ ｂｙ     

联合应用反义核酸对慢性粒细胞性白血病骨髓及外周血的净化的 …

目的：比较单独及联合应用ＢＣＲ－ＡＢＬ反义寡核苷酸（Ａｎｔｉｓｅｎｓｅ ｏｌｉｇｏｄｅｏｘｙｎｕｃｌｅｏｔｉｄｅ,ＡＳ ＯＤＮ）及Ｃ－ＭＹＢ ＡＳ ＯＤＮ对慢性粒细胞性细胞白血病（Ｃｈｒｏｎｉｃ ｍｙｅｌｏｇｅｎｏｕｓ ｌｅｕｋｅｍｉａ,ＣＭＬ）细胞及正常造血细胞的抑制作用。方法：用ＢＣＲ－ＡＢＬ ＡＳ ＯＤＮ、Ｃ－ＭＹＢ ＡＳ ＯＤＮ及错配ＯＤＮ,分别对１０例ＣＭＬ骨髓和外周血单个核细胞（Ｍｏｎ     

Experimental Study on Berberin Raised Insulin Sensitivity in Insulin Resistance Rat Models

Ｅｘｐｅｒｉｍｅｎｔａｌ　Ｓｔｕｄｙ　ｏｎ　Ｂｅｒｂｅｒｉｎ　Ｒａｉｓｅｄ　Ｉｎｓｕｌｉｎ　Ｓｅｎｓｉｔｉｖｉｔｙ　ｉｎ　Ｉｎｓｕｌｉｎ　Ｒｅｓｉｓｔａｎｃｅ　Ｒａｔ　ＭｏｄｅｌｓＧＡＯＣｏｎｇ－ｒｏｎｇ（高从容），ＺＨＡＮＧＪｉａ－ｑｉｎｇ（张家庆...     

原发性下肢浅静脉曲张氧自由基损伤及Aescuven Forte的拮抗作用

目的：探讨下肢浅静脉曲张患者氧自由基损伤及强力脉痔灵（ＡｅｓｃｕｖｅｎＦｏｒｔｅ）对其损伤指标－血清过氧化氢酶（ＳＯＤ），谷胱甘肽还原酶（ＧＳＨ）及过氧化脂质（ＬＰＯ）水平的影响。方法：对６０例原发性下肢浅静脉曲张患者进行用药前后血清ＳＯＤ、ＧＳＨ、ＬＰＯ测定。结果：该病患者血清存在高水平ＬＰＯ及低水平ＳＯＤ、ＧＳＨ；应用ＡｅｓｃｕｖｅｎＦｏｒｔｅ可有效地纠正其血清ＳＯＤ、ＧＳＨ、ＬＰＯ水平。结论：拮抗自由基损伤可能是ＡｅｓｃｕｖｅｎＦｏｒｔｅ治疗下肢浅静脉曲张及其并发症的机理之一     

Intrahepatic peripheral cholangiocarcinoma: CT features in 18 pathologically proven cases

Ｉｎｔｒａｈｅｐａｔｉｃｐｅｒｉｐｈｅｒａｌｃｈｏｌａｎｇｉｏｃａｒｃｉｎｏｍａ：ＣＴｆｅａｔｕｒｅｓｉｎ１８ｐａｔｈｏｌｏｇｉｃａｌｙｐｒｏｖｅｎｃａｓｅｓＣｈｅｎＨｕｉ’ｅｎ陈惠恩ａｎｄＨｕｉＹｕｘｉｎ回昱欣ＤｅｐａｒｔｍｅｎｔｏｆＤｉａｇｎｏｓ...     

Advances in the study on rheological behavior of leukocyte during severe shock.

ＡＤＶＡＮＣＥＳＩＮＴＨＥＳＴＵＤＹＯＮＲＨＥＯＬＯＧＩＣＡＬＢＥＨＡＶＩＯＲＯＦＬＥＵＫＯＣＹＴＥＤＵＲＩＮＧＳＥＶＥＲＥＳＨＯＣＫＺｈａｏＫｅｓｅｎ赵克森ＤｅｐａｒｔｍｅｎｔｏｆＰａｔｈｏｐｈｙｓｉｏｌｏｇｙ，ＦｉｒｓｔＭｉｌｉｔａｒｙＭｅｄｉｃ...